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| 1 | X-ray imaging of 30 year old wine grape wood reveals cumulative impacts of rootstocks on scion secondary growth and Ravaz index显示文摘Annual rings from 30 year old vines in a California rootstock trial were measured to determine the effects of 15 different rootstocks on Chardonnay and Cabernet Sauvignon scions.Viticultural traits measuring vegetative growth,yield,berry quality,and nutrient uptake were collected at the beginning(1995 to 1999)and end(2017 to 2020)of the lifetime of a vineyard initially planted in 1991 and removed in 2021.X-ray Computed Tomography(CT)was used to measure ring widths in 103 vines.Ring width was modeled as a function of ring number using a negative exponential model.Early and late wood ring widths,cambium width,and scion trunk radius were correlated with 27 traits.Modeling of annual ring width shows that scions alter the width of the first rings but that rootstocks alter the decay of later rings,consistently shortening ring width throughout the lifetime of the vine.Ravaz index,juice pH,photosynthetic assimilation and transpiration rates,and instantaneous water use efficiency are correlated with scion trunk radius.Ultimately,our research indicates that rootstocks modulate secondary growth over years,altering physiology and agronomic traits.Rootstocks act in similar but distinct ways from climate to modulate ring width,which borrowing techniques from dendrochronology,can be used to monitor both genetic and environmental effects in woody perennial crop species. | ZoëMigicovsky Michelle Y.Quigley Joey Mullins Tahira Ali Joel F.Swift Anita Rose Agasaveeran Joseph D.Dougherty Brendan Michael Grant Ilayda Korkmaz Maneesh Reddy Malpeddi Emily L.McNichol Andrew W.Sharp Jackie L.Harris Danielle R.Hopkins Lindsay M.Jordan Misha T.Kwasniewski R.Keith Striegler Asia L.Dowtin Stephanie Stotts Peter Cousins Daniel H.Chitwood | 2023 | Horticulture Research2023，10，1： | 1 |
| 2 | From Vietnamese plants to a biflavonoid that relieves inflammation by triggering the lipid mediator class switch to resolution显示文摘Chronic inflammation results from excessive pro-inflammatory signaling and the failure to resolve the inflammatory reaction.Lipid mediators orchestrate both the initiation and resolution of inflammation.Switching from pro-inflammatory to pro-resolving lipid mediator biosynthesis is considered as efficient strategy to relieve chronic inflammation,though drug candidates exhibiting such features are unknown.Starting from a library of Vietnamese medical plant extracts,we identified isomers of the biflavanoid 8-methylsocotrin-4’-ol from Dracaena cambodiana,which limit inflammation by targeting 5-lipoxygenase and switching the lipid mediator profile from leukotrienes to specialized pro-resolving mediators(SPM).Elucidation of the absolute configurations of 8-methylsocotrin-4’-ol revealed the 2 S,γSisomer being most active,and molecular docking studies suggest that the compound binds to an allosteric site between the 5-lipoxygenase subdomains.We identified additional subordinate targets within lipid mediator biosynthesis,including microsomal prostaglandin E2 synthase-1.Leukotriene production is efficiently suppressed in activated human neutrophils,macrophages,and blood,while the induction of SPM biosynthesis is restricted to M2 macrophages.The shift from leukotrienes to SPM was also evident in mouse peritonitis in vivo and accompanied by a substantial decrease in immune cell infiltration.In summary,we disclose a promising drug candidate that combines potent 5-lipoxygenase inhibition with the favorable reprogramming of lipid mediator profiles. | Tran Thi Van Anh Alilou Mostafa Zhigang Rao Simona Pace Stefan Schwaiger Christian Kretzer Veronika Temml Carsten Giesel Paul M.Jordan Rossella Bilancia Christina Weinigel Silke Rummler Birgit Waltenberger Tran Hung Antonietta Rossi Hermann Stuppner Oliver Werz Andreas Koeberle | 2021 | Acta Pharmaceutica Sinica B2021，11，6： | 1 |
| 3 | Estimates of the prevalence of arthritis and other rheumatic conditions in the United States: Part II显示文摘 | Reva C.Lawrence David T.Felson Charles G.Helmick Lesley M.Arnold HyonChoi Richard A.Deyo SherineGabriel RosemarieHirsch Marc C.Hochberg Gene G.Hunder Joanne M.Jordan Jeffrey N.Katz Hilal MaraditKremers FrederickWolfe | 2007 | Arthritis & Rheumatism2007，，1： | 1 |
| 4 | 用于ECR离子源的超导磁体——设计与制造(英文)显示文摘Superconducting magnets are widely used in ECR ion sources.The intensity and form of the magnetic field plays an important role in the way towards higher performance sources.During the development steps,the design principles and geometries had to be adapted to reach higher fields using state-of-the-art technologies and design tools.Production,assembly,and tests of these superconducting magnets are presented and a short outlook on possible future developments is given. | A.Hobl B.Fischer C.Radermacher D.Krischel M.Jordan M.M.Reumers | 2007 | Chinese Physics C2007，31，S1： | 0 |
| 5 | 不依赖于Dicer的新型siRNA介导拟南芥DNA甲基化显示文摘DNA甲基化在转座子沉默和基因表达调控等方面有重要作用。普遍认为,在植物中,从头建立DNA甲基化由一类Dicer-like3(DCL3)加工生成的长siRNA所介导。 | Ruiqiang Ye Zulong Chen Bi Lian M.Jordan Rowley Ning Xia Jijie Chai Yan Li Xin-Jian He Andrzej T.Wierzbicki 戚益军 | 2017 | 科学新闻2017，19，4： | 0 |
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