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您的检索式：作者名="M.Cunningham"
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| 1 | Systematic review: outcome of compensated cirrhosis due to chronic hepatitis C infection显示文摘 | W.Alazawi M.Cunningham J.Dearden G. R.Foster | 2010 | Alimentary Pharmacology & Therapeutics2010，，3： | 3 |
| 2 | 带可变几何涡轮增压器柴油机的双回路废气再循环多变量控制显示文摘研究双回路废气再循环(EGR)柴油机采用多变量控制器的设计问题。发动机需控制2个EGR阀(高压阀和低压阀)、1个排气节流阀和1个可变几何涡轮增压器。提出了一种利用模型预测控制(MPC)方法,对柴油机进行适用于生产的空气管理控制。此外,概述了所提出设计的调整过程。在1台2.8L轻型柴油机上获得了设计的性能试验结果。控制器闭环性能的LA-4循环瞬态数据验证了设计过程的有效性。在整个瞬态行驶循环控制器的标定过程中,MPC从数据采集开始到建立发动机标定模型仅用10天时间。 | N.Khaled M.Cunningham J.Pekar A.Fuxman O.Santin 王晓滕 李研芳 | 2015 | 国外内燃机2015，47，4： | 1 |
| 3 | Genome-wide methylation profiling reveals differentially methylated genes in blood DNA of small-cell lung cancer patients显示文摘Dear Editor,Small-cell lung cancer(SCLC),one of the most-deadly malignant tumors,accounts for∼15%of all lung cancers.1,2 Although highly responsive to the standard chemoradiotherapy,the recurrence rate of SCLC is nearly unity,with median survival time ranging from 2–6 months.Almost all SCLC patients are inoperable,leading to the difficulty in obtaining adequate biopsy tissue for research.3 Consequently,there is an urgent need to find noninvasive biomarkers to predict the risk and provide early diagnosis of SCLC.We aimed to identify potential epigenomic markers for SCLC development in blood DNA and reveal differentially methylated genes through a multi-omics approach,from genome-wide DNA methylation profiling,followed by pathway enrichment analyses and target gene validation utilizing Gene Expression Omnibus(GEO)and Oncomine microarray databases,to TCGA PanCancer cohorts.It is known that virtually all patients with SCLC are victims of tobacco smoking,4 but it is unknown whether stopping smoking before SCLC diagnosis would influence the epigenetic biomarkers under investigation.We here report a study that identified aberrantly methylated genes between current and former smokers among SCLC patients,revealing a set of candidate biomarkers in peripheral blood DNA for better stratifying patients with high risk. | Yanqi He Calvin Wei Zhifu Sun Julie M.Cunningham Liang Wang Zong Wei Ping Yang | 2022 | Precision Clinical Medicine2022，5，3： | 0 |
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