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| 1 | 我们需要什么研究来支持将结合医学运用于临床的决策?--效益比较研究可以填补其间的沟壑吗?显示文摘在补充和结合医学临床研究中,专家和科研工作者往往片面地追求研究纲领而没有充分考虑到最终服务对象,即患者的需求。因此,以往大多数的临床研究都集中在评价治疗措施的效力,却缺乏关于其临床效果的研究数据。效益比较研究(comparative effectivenesresearch,CER)旨在通过提供对可能的最佳治疗方案利弊的比较证据,使决策者能明智选择最佳治疗方案。这种证据,较之传统意义上的RCT研究证据更普遍,更适用于对实际医疗方案的决策。重视CER将为临床循证医学的发展及政策制定提供支持。诚然,在补充和结合医学的大多数领域中,CER的数据还很匮乏,针灸研究已为CER提供了一定的证据。笔者将重点介绍CER,并对将来的研究方向提供建议。 | Claudia M.Witt 黄文静 劳力行 Brian M.Berman | 2013 | 中国中西医结合杂志2013，33，8： | 6 |
| 2 | Control of autoimmune arthritis by herbal extracts and their bioactive components显示文摘Autoimmune diseases such as rheumatoid arthritis (RA) cause significant morbidity and loss of productivity. Many potent conventionally used drugs are available for these diseases, but their prolonged use is accompanied by severe adverse effects besides a high cost.Therefore, there is an unmet need for effective but less expensive medications for RA and other autoimmune diseases. Natural plant products belonging to the traditional systems of medicine, such as the traditional Chinese medicine and Indian Ayurvedic medicine, offer a vast and promising resource in this regard. However, herbal medicinal products are often poorly characterized for their composition as well as mechanisms of action. We review here the results of our systematically performed studies aimed at defining the anti-arthritic activity of three herbal extracts, namely, modified Huo-luo-xiao-ling dan (HLXL), Celastrus aculeatus Merr., and polyphenolic fraction of green tea (Camellia sinensis), as well as a purifiedcompound Celastrol, a bioactive component of Celastrus. Specifically, we examined the effects of these herbal products on the immunological, biochemical and molecular biological effector pathways in autoimmune arthritis. We have also reviewed here related studies on these herbal products by other investigators. Taken together, we suggest further testing of these herbal products in RA patients. | Shivaprasad H.Venkatesha Brian Astry Siddaraju M.Nanjundaiah Hong R.Kim Rajesh Rajaiah Yinghua Yang Li Tong Hua Yu Brian M.Berman Kamal D.Moudgil | 2016 | Asian Journal of Pharmaceutical Sciences2016，11，2： | 2 |
| 3 | Effect of Using Photos from Authentic Video as Advance Organizers on Listening Comprehension in an FLES Chinese Class显示文摘 | LeeWilberschied Peiyan M.Berman | 2008 | Foreign Language Annals2008，，4： | 1 |
| 4 | Neural and psychological predictors of treatment response in irritable bowel syndrome patients with a 5‐HT<sub>3</sub> receptor antagonist: a pilot study显示文摘 | J. M.JARCHO L.CHANG S. M.BERMAN B.SUYENOBU B. D.NALIBOFF M. D.LIEBERMAN V. Z.AMEEN M. A.MANDELKERN E. A.MAYER | 2008 | Alimentary Pharmacology & Therapeutics2008，，3： | 1 |
| 5 | Female preferences for male golden snub-nosed monkeys vary with male age and social context显示文摘Age is a key factor affecting sexual selection,as many physical and social traits are age-related.Although studies of primate mate choice often consider particular age-related traits,few consider the collective effects of male age.We tested the hypothesis that female golden snub-nosed monkeys Rhinopithecus roxellana prefer prime aged males(10-15 years)over younger and older males.We examined a habituated,provisioned troop during a 3-year study in the Qinling Mountains,China.Prime age males were more likely to be resident males of 1-male units(OMUs)than males of other ages.Since females are free to transfer between OMUs,the number of females per OMU can be indicative of female preferences.We examined the number of females per OMU,and found that it increased with resident male age up to 7-8 years,and declined after 12 years,such that prime age resident males had more females than other resident males.Females also initiated extra-unit copulations with high-ranking prime age males at significantly higher rates than with other males.Nevertheless,females tended to transfer from OMUs with high-ranking,older resident males to those with low-ranking,younger resident males.Thus,females appear to use different strategies when choosing social mates and extra-unit mates(i.e.,different social contexts).We speculate that females may perceive early signs of aging in males and trade off the benefits and costs of high rank versus male senescence.This study lays the groundwork for future studies that examine possible direct and indirect benefits of such strategies. | Xi YANG Carol M.BERMAN Hanyu Hu Rong Hou Kang HUANG Xiaowei Wang Haitao ZHAO Chengliang WANG Baoguo Li Pei ZHANG | 2022 | Current Zoology2022，68，2： | 0 |
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