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| 1 | Future challenges in the in vitro and in vivo evaluation of biomaterial biocompatibility显示文摘As the science and engineering of biomaterials continues to expand with increased emphasis on the development of nanomaterials and tissue engineering scaffolds,emphasis also must be placed on appropriate and adequate approaches to the in vivo and in vitro evaluation of biomaterial biocompatibility/biological response evaluation.This article presents six topic areas that should be addressed by investigators as they move forward in the development of new systems for regenerative medicine.Most certainly,there are other areas that require attention to detail and a more complete understanding of the strengths and weaknesses of various experimental approaches to biomaterial/biological response evaluation.The small number of issues addressed in this article is only meant to bring to the attention of prospective investigators and authors,the importance of the development of adequate and appropriate evaluation techniques that address the unique features of biomaterials utilized in the development of new medical devices. | James M.Anderson | 2016 | Regenerative Biomaterials2016，3，2： | 7 |
| 2 | Patients direct costs to undergo TB diagnosis显示文摘Background:A major impediment to the treatment of TB is a diagnostic process that requires multiple visits.Descriptions of patient costs associated with diagnosis use different protocols and are not comparable.Methods:We aimed to describe the direct costs incurred by adults attending TB diagnostic centres in four countries and factors associated with expenditure for diagnosis.Surveys of 2225 adults attending smear-microscopy centres in Nigeria,Nepal,Ethiopia and Yemen.Adults>18 years with cough>2 weeks were enrolled prospectively.Direct costs were quantified using structured questionnaires.Patients with costs>75^(th) quartile were considered to have high expenditure(cases)and compared with patients with costs<75^(th) quartile to identify factors associated with high expenditure.Results:The most significant expenses were due to clinic fees and transport.Most participants attended the centres with companions.High expenditure was associated with attending with company,residing in rural areas/other towns and illiteracy.Conclusions:The costs incurred by patients are substantial and share common patterns across countries.Removing user fees,transparent charging policies and reimbursing clinic expenses would reduce the poverty-inducing effects of direct diagnostic costs.In locations with limited resources,support could be prioritised for those most at risk of high expenditure;those who are illiterate,attend the service with company and rural residents. | Rachel M.Anderson de Cuevas Lovett Lawson Najla Al-Sonboli Nasher Al-Aghbari Isabel Arbide Jeevan B.Sherchand Emenyonu E.Nnamdi Abraham Aseffa Mohammed A.Yassin Saddiq T.Abdurrahman Joshua Obasanya Oladimeji Olanrewaju Daniel Datiko Sally J.Theobald Andrew Ramsay S.Bertel Squire Luis E.Cuevas | 2016 | Infectious Diseases of Poverty2016，5，1： | 1 |
| 3 | Interrelationship of soil moisture and temperature to sylvatic plague cycle among prairie dogs in the Western United States显示文摘Plague,caused by Yersinia pestis,is a flea-borne disease that is endemic in areas throughout the world due to its successful maintenance in a sylvatic cycle,mainly in areas with temperate climates.Burrowing rodents are thought to play a key role in the enzootic maintenance as well as epizootic outbreaks of plague.In the United States,prairie dogs(Cynomys),rodents(Muridae),and ground squirrels(Spermophilus)are susceptible to infection and are parasitized by fleas that transmit plague.In particular,prairie dogs can experience outbreaks that rapidly spread,which can lead to extirpation of colonies.A number of ecological parameters,including climate,are associated with these epizootics.In this study,we asked whether soil parameters,primarily moisture and temperature,are associated with outbreaks of plague in black-tailed prairie dogs and Gunnison’s prairie dogs in the Western United States,and at what depth these associations were apparent.We collected publicly available county-level information on the occurrence of population declines or colony extirpation,while historical soil data was collected from SCAN and USCRN stations in counties and states where prairie dogs have been located.The analysis suggests that soil moisture at lower depths correlates with colony die-offs,in addition to temperature near the surface,with key differences within the landscape ecology that impact the occurrence of plague.Overall,the model suggests that the burrow environment may play a significant role in the epizootic spread of disease amongst black-tailed and Gunnison’s prairie dogs. | Cassandra D.PAULING Deborah L.FINKE Deborah M.ANDERSON | 2021 | Integrative Zoology2021，16，6： | 1 |
| 4 | Lactosylated N-Alkyl polyethylenimine coated iron oxide nanoparticles induced autophagy in mouse dendritic cells显示文摘Dendritic cell(DC)-based vaccines have shown promising therapeutic results in cancer and some immune disorders.It is critical to track in vivo migration behaviours of DCs and monitor the whole process dynamically and non-invasively.Superparamagnetic iron oxide(SPIO)nanoparticles are chosen for DC labelling under magnetic resonance imaging(MRI)because of their proven biosafety as contrast agents.However,when used for cell labelling,sensitive biological indicators such as cell autophagy may be helpful to better understand the process and improve the probe design.Here,lactosylated N-Alkyl polyethylenimine coated SPIO nanoparticles are used for DC labelling.This probe shows satisfactory cell labelling efficiency and low cytotoxicity.In this study,autophagy was used as a key factor to understand how DCs react to nanoparticles after labelling.Our results demonstrate that the nanoparticles can induce protective autophagy in DCs,as inhibition of the autophagy flux could lead to cell death.Meanwhile,the nanoparticles induced autophagy could promote DC maturation which is an essential process for its migration and antigen presentation.Autophagy induced DC maturation is known to enhance the vaccine functions of DCs,therefore,our results suggest that beyond the MRI tracking ability,this probe might enhance therapeutic immune activation as well. | Taipeng Shen Wencheng Zhu Li Yang Li Liu Rongrong Jin Jimei Duan James M.Anderson Hua Ai | 2018 | Regenerative Biomaterials2018，5，3： | 1 |
| 5 | ‘One flew over the psychiatric unit’: mental illness and the media显示文摘 | M.ANDERSON | 2003 | Journal of Psychiatric and Mental Health Nursing2003，，3： | 1 |
| 6 | Lesioning of TRPV1 expressing primary afferent neurons prevents PAR‐2 induced motility, but not mechanical hypersensitivity in the rat colon显示文摘 | S. K.Suckow E. M.Anderson R. M.Caudle | 2012 | Neurogastroenterology & Motility2012，，3： | 1 |
| 7 | Injectable rhBMP‐2‐loaded chitosan hydrogel composite: Osteoinduction at ectopic site and in segmental long bone defect显示文摘 | LudmilaLuca Anne‐LaureRougemont Beat H.Walpoth LudovicBoure AndreaTami James M.Anderson OlivierJordan RobertGurny | 2010 | J Biomed Mater Res2010，，1： | 1 |
| 8 | Temperature responses of carbon mineralization in conifer forest soils from different regional climates incubated under standard laboratory conditions显示文摘 | PanagiotisDalias Jonathan M.Anderson PierreBottner Marie‐MadeleineCo?teaux | 2008 | Global Change Biology2008，，2： | 1 |
| 9 | Clinical uses of brain natriuretic peptide in diagnosing and managing heart failure显示文摘 | Kelley M.Anderson | 2008 | Journal of the American Academy of Nurse Practitioners2008，，6： | 1 |
| 10 | 发射操作系统(LPS)航天飞机连接器分析网络(SCAN)显示文摘对于Kennedy空间中心(KSC)的一次典型着陆发射,有多至2000或者更多的轨道飞行器的电动/电子连接器要经受影响线路功能的分离、重新配接和重新测试。每一连接器分离大概要断开多至128条线路。SCAN是一种高度复杂的联机交互式软件系统,它能跟踪和及时报告全部机上连接器的当前线路状况与所设计的线路配置对比情况。经过线路连续性跟踪,就能对连接器的分离、所规划的调整工作以及LRU的调动/替换作出预先的估计。SCAN对于运载工具测试时所遇到的问题具有联机分析能力。因此,通过线路屏幕图象和联机线路扫描就能更有效地查出故障。 | D.Gerken M.Anderson 黄祥明 | 1991 | 国外导弹与航天运载器1991，，7： | 0 |
| 11 | 超临界流体的自然循环传热与流动稳定性研究显示文摘威斯康星麦迪逊大学(UW)建立了一个超临界水(SCW)环路,阿贡国家实验室(ANL)建立了一个超临界CO2(SCCO2)环路。运用实验,理论和数值分析方法来研究超临界流体的自然循环传热和流动稳定性行为。这里给出了环路的设计细节,找到了UW环路垂直和水平加热区的初步传热系数发展了一种数值运算法则,用来设计设备、计算传热和研究可能存在的自然循环不稳定性。 | R.Jain J.Licht M.Anderson M.Corradini S.Lomperski D.H.Cho 黄军 赖举 卢冬华 | 2004 | 国外核动力2004，25，4： | 0 |
| 12 | Recent investigations of shock wave effects and interactions显示文摘Despite over fifty years of research on shock wave boundary layer effects and interactions,many related technical issues continue to be controversial and debated.The present survey provides an overview of the present state of knowledge on such effects and interactions,including discussions of:(i)general features of shock wave interactions,(ii)test section configurations for investigation of shock wave boundary layer interactions,(iii)origins and sources of unsteadiness associated with the interaction region,(iv)interactions which included thermal transport and convective heat transfer,and(v)shock wave interaction control investigations.Of particular interest are origins and sources of low-frequency,large-scale shock wave unsteadiness,flow physics of shock wave boundary layer interactions,and overall structure of different types of interactions.Information is also provided in regard to shock wave investigations,where heat transfer and thermal transport were important.Also considered are investigations of shock wave interaction control strategies,which overall,indicate that no single shock wave control strategy is available,which may be successfully applied to different shock wave arrangements,over a wide range of Mach numbers.Overall,the survey highlights the need for additional understanding of fundamental transport mechanisms,as related to shock waves,which are applicable to turbomachinery,aerospace,and aeronautical academic disciplines. | P.M.Ligrani E.S.McNabb H.Collopy M.Anderson S.M.Marko | 2020 | Advances in Aerodynamics2020，2，1： | 0 |
| 13 | 《名称词的语法》介绍显示文摘《名称词的语法》(The Grammar of Names)一书2007年由英国牛津大学出版社出版。作者John M.Anderson是爱丁堡大学名誉教授。全书分为3部分,9个章节。 | John M.Anderson 马军 | 2012 | 当代语言学2012，14，2： | 0 |
| 14 | Impact of single annual treatment and four-monthly treatment for hookworm and Ascaris lumbricoides,and factors associated with residual infection among Kenyan school children显示文摘Background:School-based deworming is widely implemented in various countries to reduce the burden of soil-transmitted helminths(STHs),however,the frequency of drug administration varies in different settings.In this study,we compared the impact of a single annual treatment and 4-monthly treatment over a follow-up among Kenyan school children,and investigated the factors associated with residual infection.Methods:We performed a secondary analysis of data from a randomized trial investigating whether deworming for STHs alters risk of acquiring malaria.Children received either a single treatment or 4-monthly albendazole treatments were followed longitudinally from February 2014 to October 2014.The relative impact of treatment and factors associated with residual infections were investigated using mixed-effects regression models.Predisposition to infection was assessed based on Spearman’s rank and Kendall’s Tau correlation coefficients.Results:In the 4-monthly treatment group,the proportion of children infected with hookworm decreased from 59.9 to 5.7%,while Ascaris lumbricoides infections dropped from 55.7 to 6.2%.In the single treatment group,hookworm infections decreased over the same time period from 58.7 to 18.3%(12.6%absolute difference in reduction,95%CI:8.9-16.3%),and A.lumbricoides from 56.7 to 23.3%(17.1%absolute difference in reduction,95%CI:13.1-21.1%).There was strong evidence for predisposition to both STH types.Residual hookworm infection among children on 4-monthly treatment were associated with male sex and baseline nutritional status,whereas A.lumbricoides infection was associated with individual and school-level infection at baseline,latrine cleanliness at schools.Conclusions:This study found that 4-monthly treatment w more effective than single annual treatment.Repeated treatments led to dramatic reductions in the intensities of STHs,but did not completely clear infections among school children in Kenya,a presumed reflection of reinfection in a setting where there is ongoing transmission. | Stella Kepha Charles S.Mwandawiro Roy M.Anderson Rachel L.Pullan Fred Nuwaha Jorge Cano Sammy M.Njenga Maurice R.Odiere Elizabeth Allen Simon J.Brooker Birgit Nikolay | 2017 | Infectious Diseases of Poverty2017，6，1： | 0 |
| 15 | Foreword显示文摘This special issue of Regenerative Biomaterials presents 13 manuscriptsprovided by participants of the China–US Forum on GrandChallenges for Biomaterials in the 21st Century. This forum washeld on November 17, 2015, in Chengdu, China and was chaired bythe Editor of Regenerative Biomaterials, Professor Xingdong Zhangand Professor Nicholas Peppas. The participants of this forum wereinternationally recognized experts from the United States ofAmerica and the Peoples Republic of China. It is noteworthy thatthe United States speakers were members of the National Academyof Engineering, Section 2. Bioengineering, and most of the Chinesespeakers were members of the Chinese Academy of Engineering orthe Chinese Academy of Sciences. The overlying theme of this forumand this resultant special issue is the impact that the biological environmentin which biomaterials will be utilized is now recognized asproviding a wide variety of significant and impactful challenges thatmust be overcome if biomaterials are to achieve clinical application. | James M.Anderson | 2016 | Regenerative Biomaterials2016，3，2： | 0 |
| 16 | 爱尔夏公牛体内GnRH诱发的睾酮高峰及精子活力与受精力之间的关系显示文摘研究了58头芬兰爱尔夏公牛促性腺激素释放激素(GnRH)诱发的睾酮高峰、受精力和精子活力之间的关系。试验公牛选自6个人工授精(AI)中心的约420头公牛。从58头试验公牛中随机选出精子活力好的公牛,其他41头公牛精子活力低,其中7头公牛的精液质量低劣到不能用于人工授精。于采血前2.5小时肌肉注射促性腺激素释放激素,精子活力好的17头公牛血清睾酮浓度均值最高。本研究中,精子活力好的公牛GnRH诱发的血清睾酮高峰显著地高于精子活力低的公牛。本研究中(包括精子活力差的公牛)观察到睾酮浓度与受精力(NR%)之间呈正相关关系。 | M.Anderson 康文彪 | 1992 | 国外畜牧学(草食家畜)1992，，5： | 0 |
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