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27篇 您的检索式：作者名="Luo WC"

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	题名	作者	年代	出处	被引量
1	Inhibition of angiogenesis and HCT-116 xenograft tumor growth in mice by kallistatin显示文摘AIM: To investigate the inhibitory effect of kallistatin (KAL) on angiogenesis and HCT-116 xenograft tumor growth. METHODS: Heterotopic tumors were induced by subcutaneous injection of 2 × 106 HCT-11 cells in mice. Seven days later, 2 × 1011 rAAV-GFP or rAAV-KAL was injected intratumorally (n = 5 for each group). The mice were sacrificed at d 28, by which time the tumors in the rAAV-GFP group had grown to beyond 5% of the total body weight. Tumor growth was measured by calipers in two dimensions. Tumor angiogenesis was determined with tumor microvessel density (MVD) by immunohistology. Tumor cell proliferation was assessed by Ki-67 staining. RESULTS: Intratumor injection of rAAV-KAL inhibited tumor growth in the treatment group by 78% (171 ± 52 mm3) at d 21 after virus infection compared to the control group (776 ± 241 mm3). Microvessel density was significantly inhibited in tumor tissues treated with rAAV-KAL. rAAV-KAL also decreased the proportion of proliferating cells (Ki-67 positive cells) in tumors compared with the control group.CONCLUSION: rAAV-mediated expression of KAL inhibits the growth of colon cancer by reducing angiogenesis and proliferation of tumor cells, and may provide a promising anti-angiogenesis-based approach to the treatment of metastatic colorectal cancer.	Yong Diao Jian Ma Wei-Dong Xiao Jia Luo Xin-Yan Li Kin-Wah Chu Peter WC Fung Nagy Habib Farzin Farzaneh Rui-An Xu	2007	World Journal of Gastroenterology2007，13，34：	15
2	RGD- conjugated Gold nanorods induce radiosensitization in melanoma cancer cells by downregu- lating alpha(v)beta(3) expression显示文摘	Xu WC Luo T Li P	2012	Int J Nanomedicine2012，7，：	1
3	HBeAg and hepatitis B virus DNA as outcome predictors during therapy with peginterferon alfa-2a forHBeAg-positive chronic hepatitis B 显示文摘	Fried MW Piratvisuth T Lau GK Marcellin P Chow WC Cooksley G Luo KX Paik SW Liaw YF Button P Popescu M	2008	Hepatology2008，47，2：	1
4	Segmental ureterec- tomy does not compromise the oncologic outcome compared with nephroureterectomy for pure ureter cancer显示文摘	HUNG SY YANG WC LUO HL	2014	Int Urol Neph- rol2014，46，：	1
5	3D-QSAR and molecular do-cking studies of benzaldehyde thiosemicarbazone,benzaldehyde,benzoic acid,and their derivatives as phenoloxidase inhibitors显示文摘	Xue CB Zhang L Luo WC	2007	Bioorgan Med Chem2007，15，5：	1
6	Toxicity of cytosine against themustard aphid Lipaphis erysimi Kaltenbach (Homoptera:Aphididae) and its effect on esterase显示文摘	Luo WC Li YS Chiu SF	1999	Pesticide Biochemistry and Physiology1999，65，1：	1
7	High - resolution structure of the p53 core domain: implications for binding small -molecule stabilizing compounds显示文摘	Ho WC Luo C Zhao K	2005	Acta Crystallogr D Biol Crystallogr2005，62，12：	1
8	Design and application of a new series of gallbladder endoscopes that facilitate gallstone re- moval without gallbladder excision显示文摘	Qiao T Huang WC Luo XB	2012	Rev Sci Instrum2012，83，1：	1
9	Preparation and dielectric properties of B-doped SiC powders by combustion synthesis 显示文摘	SU X L ZHOU WC LI Z M LUO F DU H L ZHU D M	2009	Mater Res Bull2009，42，：	1
10	In situ reconstruction of septic aortic pseudoaneurysm due to Salmonella or Streptococcus microbial aortitis: long-term follow-up显示文摘	Luo CY Ko WC Kan CD	2003	J Vasc Surg2003，38，5：	1
11	The HMG-CoA reductase inhibitor simvastatin activates the protein kinase Akt and promotes angiogenesis in normocholesterolemic animals显示文摘	Luo Z Shiojima I Bialik A Fulton D Lefer DJ Sessa WC	2000	Nat Med2000，6，9：	1
12	Design and application of a new series of gallbladder endoscopes that faciiitate gallstone removal without gallbladder excision显示文摘	Qiao T Huang WC Luo XB	2012	Rev Sci Instum2012，83，1：	1
13	Design and applica- tion of a new series of gallbladder endoscopes that facili- tate gallstone removal without gallbladder excision 显示文摘	Qiao T Huang WC Luo XB	2012	Review of Scientific Instruments2012，83，15：	1
14	WW domain containing E3 ubiquitin protein ligase 1 (WWP1) negatively regulates TLR4- mediated TNF a and IL-6 production by proteasomal degrada- tion of TNF receptor associated {actor 6 (TRAF6)显示文摘	Lin XW Xu WC Luo JG	2013	PLoS One2013，8，67：	1
15	Segmental ureterectomy does not compromise the oncologic outcome compared with nephroureterectomy for pure ureter cancer显示文摘	Hung SH Yang WC Luo HL	2014	Int Urol Nephrol2014，46，5：	1
16	WW domain containing E3 ubiquitin protein ligase 1 ( WWP1 ) negatively regulates TLR4-mediated TNF-et and I1,-6 production by proteasomal degradation of TNF receptor associated factor 6 ( TRAF6 )显示文摘	Lin XW Xu WC Luo JG	2013	PLoS One2013，8，67：	1
17	High-resolution structure of the p53 core domain,, implications for binding small-molecule stabilizing compounds显示文摘	Ho WC Luo C Zhao K	2006	Acta Crystallogr D Biol Crystallogr2006，62，12：	1
18	Design and applica- tion of a new series of gallbladder endoscopes that facili- tate gallstone removal without gallbladder excision 显示文摘	Chiao T Huang WC Luo XB	2012	Review of Scientific Instruments2012，83，1：	1
19	Analgesic and anti-inflammatory activities of[6]-gingerol显示文摘	Young HY Luo YL Cheng HY Hsieh WC Liao JC Peng WH		0，，1：	1
20	Summary of mucosolvin clinical effects显示文摘	Luo WC Zhuo YJ	1992	Chinese New Drugs Joumal1992，1，5：	1

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