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| 1 | 1 Effects ofpotassium supplemen-tmion on the recovery of thyrotoxic periodic paralysis显示文摘 | Lu KC Hsu YJ Chiu JS eta | 2004 | Am JEmergMed2004，22，7： | 1 |
| 2 | Regulation of C-C chemokine production by routine T cells by CD28/B7 costimulation显示文摘 | Herold KC Lu J Rulifson I | 1997 | J Immunol1997，159，： | 1 |
| 3 | Bone Turnover markers predict changes in bone mineral density after parathyroidectomy in patients with renal hyperparathyroidism显示文摘 | Lu KC Ma WY Yu JC | 2012 | Clin Endocrinoi (Oxf)2012，76，6： | 1 |
| 4 | 显示文摘 | Yucan Zhu Junguang Lu | 1991 | Phys Lett B1991，265，： | 1 |
| 5 | Pluronic L-81 ameliorates diabetic symptoms in db/db mice through transcriptional regulation of microsomal triglyceride transfer protein显示文摘AIM: To test whether oral L-81 treatment could im-prove the condition of mice with diabetes and to investigate how L-81 regulates microsomal triglyceride transfer protein (MTP) activity in the liver. METHODS: Genetically diabetic (db/db) mice were fed on chow supplemented with or without L-81 for 4 wk. The body weight, plasma glucose level, plasma lipid profile, and adipocyte volume of the db/db mice were assessed after treatment. Toxicity of L-81 was also evaluated. To understand the molecular mecha-nism, HepG2 cells were treated with L-81 and the effects on apolipoprotein B (apoB) secretion and mRNA level of the MTP gene were assessed.RESULTS: Treatment of db/db mice with L-81 sig-nificantly reduced and nearly normalized their body weight, hyperphagia and polydipsia. L-81 also markedly decreased the fasting plasma glucose level, improved glucose tolerance, and attenuated the elevated levels of plasma cholesterol and triglyceride. At the effective dosage, little toxicity was observed. Treatment of HepG2 cells with L-81 not only inhibited apoB secretion, but also signif icantly decreased the mRNA level of the MTP gene. Similar to the action of insulin, L-81 exerted its effect on the MTP promoter. CONCLUSION: L-81 represents a promising candidate in the development of a selective insulin-mimetic mol-ecule and an anti-diabetic agent. | Wo-Shing Au Li-Wei Lu Sidney Tam Otis King Hung Ko Billy KC Chow Ming-Liang He Samuel S Ng Chung-Man Yeung Ching-Chiu Liu Hsiang-Fu Kung Marie C Lin | 2009 | World Journal of Gastroenterology2009，15，24： | 1 |
| 6 | Gefitinib-indnced epidermal growth factor receptor-independent keratinocyte apoptosis is mediated by the JNK activation pathway 显示文摘 | Lu PH Kuo TC Chang KC | 2011 | Br J Dermatol2011，164，1： | 1 |
| 7 | Does the multidimensional grad- ing system (BODE) correspond to differences in health status of patients with COPD? 显示文摘 | Ong KC Lu SJ SohCS | 2006 | Int J Chron Obstruct Pulmon Dis2006，1，1： | 1 |
| 8 | Role of T cells in type 2diabetic nephropathy显示文摘 | Wu CC Sytwu HK Lu KC | 2011 | Exp Diabetes Res2011，2011，51： | 1 |
| 9 | Molecular Techniques in the Diagnosis of Central Nervous System Infection显示文摘 | Lu HZ Bloch KC Tang YW | 2002 | Curr Infect Dis Rep2002，4，4： | 1 |
| 10 | The Effects of Music asTherapy on the Overall Well - Being of Elderly Patients onMaintenance Hemodialysis显示文摘 | Lin YJ Lu KC Chen CM | 2012 | Biological research for nurs-ing2012，14，3： | 1 |
| 11 | Safety and efficacy of twice-daily exenatide in Taiwanese patients with inadequately controlled type 2diabetes mellitus显示文摘 | Lu CH Wu TJ Shih KC | 2013 | J Formos Med Assoc2013，112，3： | 1 |
| 12 | Does the multidimensional grading system (BODE) correspond to differences in health status of patients with COPD?显示文摘 | Ong KC Lu SJ Soh CS | 2006 | lnt J Chron Obstruct Pulmon Dis2006，1，1： | 1 |
| 13 | Comparison of biochemical aromatase activity with aromatase immunohistochemistry in human breast carcinoma显示文摘 | Shenton KC Dowsett M Lu Q | 1998 | Breast Cancer Res Treat1998，49，1： | 1 |
| 14 | Role of ereatine phosphokinase in predicting acute renal failure in hypocaleemic exertional heat stroke显示文摘 | Shieh SD Un YF Lu KC | 1992 | Am J Nephrol1992，12，： | 1 |
| 15 | Stage IIl & IV colon and rectal cancers share a similar genetic profile : a review of the Oregon Coloreetal Cancer Registry显示文摘 | Gawlick U Lu KC Douthit MA | 2013 | Am J Surg2013，205，5： | 1 |
| 16 | Energy netabolism in exertional heat stroke with acute renal failure 显示文摘 | Lu KC lin SH | 1997 | Nephrol Dial Transplant1997，12，： | 1 |
| 17 | The pre-emptive analgesic effect of a cyclooxygenase-2 inhibitor in a rat model of acute postoperative pain显示文摘 | Chen JJ Hung KC Lu K | 2012 | Anaesthesia2012，67，11： | 1 |
| 18 | Role of creatine phosphokinase in predicting acute renal failure in hypocalcemic exertional heat stroke显示文摘 | Shieh SD Un YF Lu KC | 1992 | Am J Nephrol1992，12，4： | 1 |
| 19 | Role of circulating cytokines and chemokines in exertional heat stroke显示文摘 | Lu KC Wang JY Lin SH | 2004 | Crit Care Med2004，32，2： | 1 |
| 20 | Bone turnover markers predict changes in bone mineral density after parathyroidectomy in patients with renal hyperparathyroidism 显示文摘 | Lu KC Ma IV Yu JC | 2012 | Clin Endocrinol (Oxf)2012，76，： | 1 |
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