|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Practice of breast self-examination among high risk Chinese women in Hong Kong显示文摘The incidence of breast cancer in Hong Kong is increasing and breast self examination (BSE) as a screening tool is becoming more popular, especially among first degree relatives (FDR) of breast cancer victims BSE may be more applicable to Chinese women as their breast size is smaller This study explores the BSE practice in this group of women Methods A cross sectional study was conducted by sending questionnaires to 330 FDR of breast cancer patients treated in the Department of Surgery, University of Hong Kong BSE behavior was studied with respect to its frequency, awareness, completeness and confidence of practice Results 110 subjects returned the questionnaires with a response rate of 33% The mean age of the respondent was 37 years Only 57 women (52%) were practicers The practicers have a stronger BSE awareness ( P <0 01) and a lower mean score on thought barriers ( P =0 002) than the non practicers 40% of the practicers gain their BSE knowledge through clinicians and their mean period of practice was 3 2 years 68% of the practicers performed BSE completely The overall confidence rate was 35%, but the rate was 43% among those who performed complete BSE Thirteen factors possibly related to the completeness and rate of confidence of BSE examination were studied The only factor that significantly determined completeness was the time spent for each examination ( P =0 002) The complete practicers required a longer time than the incomplete practicers (6 60 and 2 96?min, respectively) Women with a stronger BSE intention ( P =0 001) and a lower mean score on thought barriers ( P =0 001) performed the examination confidently Conclusions Slightly over half of the FDR practice BSE The majority perform a complete BSE but they are not confident in finding abnormalities Women spending more time on BSE are associated with a higher rate of completeness However, only those with a stronger BSE intention and lesser thought barriers are more confident in their | Kelvin K C Ng, Fung S Y and Louis W C Chow DepartmentofSurgery (NgKKCandChowLWC)&NursingStudies (FungSY ) ,TheUniversityofHongKong ,QueenMaryHospital ,HongKong ,China | 2000 | Chinese Medical Journal2000，，12： | 4 |
| 2 | Ron receptor-dependent gene regulation in a mouse model of endotoxin-induced acute liver failure显示文摘BACKGROUND:Prior experimentation has shown that loss of the tyrosine kinase(TK) signaling domain of the Ron receptor leads to marked hepatocyte protection in a model of lipopolysaccharideinduced acute liver failure(ALF) in D-galactosamine(GalN)sensitized mice.The aim of this study was to identify the role of Ron in the regulation of hepatic gene expression.METHODS:Microarray analyses were performed on liver RNA isolated sequentially from wild-type(WT) and TK-/mice during the progression of ALF.Gene array data were validated using Western and immunohistochemistry analyses as well as with ex vivo culture systems.RESULTS:At baseline,101 genes were differentially expressed between WT and TK-/-livers,which regulate processes involved in hypoxia,proliferation,apoptosis and metabolism.One hour after ALF induction,WT livers exhibited increased cytokine expression compared to TK-/-livers,and after 4 hours,an induction of suppressor of cytokine signaling(SOCS) genes as well as JAK-STAT pathway activation were prominent in TK-/livers compared to controls.CONCLUSION:Our studies suggest a novel hepato-protective mechanism in Ron TK-/-mice wherein increased and sustained SOCS production and JAK-STAT activation in the hepatocyte may inhibit the destructive proinflammatory milieu and promote survival factors which blunt hepatic death and the ensuing development of ALF. | Rishikesh M Kulkarni Louis W Kutcher William D Stuart Daniel J Carson Mike A Leonis Susan E Waltz | 2012 | Hepatobiliary & Pancreatic Diseases International2012，11，4： | 3 |
| 3 | Tei指数评价Duchenne进行性肌营养不良症患者心功能显示文摘 | 吴进 Louis I Bezold Ricardo H Pignatelli Benjamin W Eidem | 2005 | 中华超声影像学杂志2005，14，5： | 2 |
| 4 | Potential des zusammenwirkens von modernen kraftstoffen und kunftigen antriebskonzepten 显示文摘 | Steiger W Warnecke W Louis J | 2003 | ATZ edition2003，03，： | 1 |
| 5 | Time-splitting methods for elastic models using forward time schemes显示文摘 | Louis J W William C S | 2002 | Mon Wea Rev2002，130，22： | 1 |
| 6 | Understanding the new allele prob-lem显示文摘 | Klitz W Hedrick P Louis E | 2011 | Tissue Antigens2011，77，5： | 1 |
| 7 | Interleukin 10 controls neutrophilic infiltration,hepatocyte proliferation and liver inflammation and fibrosis显示文摘 | Louis H Vanlaethem JL Wa W | 1998 | Hepatol1998，28，6： | 1 |
| 8 | Importance of the forest canopy to flux of methylmercury and total mercury to boreal ecosystems显示文摘 | Vincent L Louis S T John W M Kelly C A | 2001 | Environmental Science and Technology2001，35，： | 1 |
| 9 | Effect of Carvedilol in comparison with metoprolol on myocardial collagen postinfarction 显示文摘 | Shan W Louis C John ES | 2000 | J Am Coil Cardio2000，36，： | 1 |
| 10 | Recent trends in the de- velopment of health management 显示文摘 | Edingtond W Louis Y Ku KulI | 2001 | Health Management Re- search2001，76，103： | 1 |
| 11 | Inhibition of the mammalian β-lactamase renal dipeptidase(Dehydropeptiolase-Ⅰ)by(Z)-2-(aeylamino)-3-substituted-propenonie acids显示文摘 | Donald W G Wallace T A Louis B | 1987 | J Med Chem1987，30，6： | 1 |
| 12 | Preparation of glycyrrhizinic acid, the electrolyte-active principle of liquorice: its effects upon metabolism and upon pituitary-adrenal function in man 显示文摘 | Louis L H Conn J W | 1956 | J Lab Clin Med1956，106，1： | 1 |
| 13 | Grain size dependence of sliding wear in tetragonal zirconia polycrystals 显示文摘 | H Yingjie W Louis J B Anthonie | 1996 | J Am Ceram Soc1996，79，12： | 1 |
| 14 | The 2007 WHO classification oftumours of the central nervous system显示文摘 | Louis DN Ohgaki H W iestlerOD etal | 2007 | Acta Neuropathol2007，114，2： | 1 |
| 15 | Recent trends in the de- velopment of health management 显示文摘 | Edingtond W Louis Y KuKu II | 2001 | Health Management Re- search2001，76，103： | 1 |
| 16 | Investigation of skull formation in a blast furnace hearth 显示文摘 | ZHAO Yongfu FU Dong LHERBIER LOUIS W | 2014 | Steel Research Int2014，85，5： | 1 |
| 17 | Assessing Reseller Performance from the Perspective of the Supplier显示文摘 | Kumar Nirmalya Louis W Stern Ravi S Achrol | 1992 | Journal of Marketing Research1992，29，5： | 1 |
| 18 | Ischemia reduce CGRP-induced cerebral vaschlar dilatian in piglegts显示文摘 | Louis TM Meng W Bad F | 1996 | Stroke1996，27，1： | 1 |
| 19 | Trimalleolar Fractures显示文摘 | W C WARNER LOUIS A. FARBER | 1965 | Southern Medical Journal1965，，10： | 1 |
| 20 | Replacement of alfalfa neutral detergent fiber with a combination of nonforage fiber sources显示文摘 | PERRY W CLARK S LOUIS E | 1997 | Journal of Dairy Science1997，80，： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员