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1024篇 您的检索式:作者名="Lou M"
    题名 作者 年代 出处 被引量
1Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase显示文摘包含 methyltransferase 建筑群的象 3 一样的 methyltransferase (METTL3 ) 催化 N6-methyladenosine (m6A ) 形成,一个新奇 epitranscriptomic 标记;然而,这建筑群的性质仍然保持大部分未知。这里,我们报导人的 m6A methyltransferase 建筑群, Wilm 的肿瘤 1 伙伴蛋白质(WTAP ) 和象 14 一样的 methyltransferase (METTL14 ) 的二个新部件。WTAP 与 METTL3 和 METTL14 交往,并且为他们的本地化被要求进在 vivo 与处理因素的 pre-mRNA 并且为 m6A methyltransferase 的催化活动充实的原子点缀。RNA 的多数在 vivo 由 WTAP 和 METTL3 跳了代表包含一致 m6A 主题的 mRNAs。当 WTAP 不在时, METTL3 的 RNA 有约束力的能力强烈被减少,建议 WTAP 可以工作调整到 mRNA 目标的 m6A methyltransferase 建筑群的招募。而且,在有 photoactivatable-ribonucleoside-enhanced crosslinking 和 immunoprecipitation (同等片断) 的联合的 transcriptomic 分析说明那 WTAP 和 METTL3 调整涉及抄写并且 RNA 处理的基因拼接的表示和选择。在 zebrafish 胚胎的调停 Morpholino 的击倒的指向 WTAP 或 METTL3 引起了织物区别缺点并且增加了 apoptosis。这些调查结果提供 WTAP 可以在 m6A methyltransferase 建筑群作为一个规章的子单元工作并且在 RNA 的 epitranscriptomic 规定起一个关键作用的充分证据新陈代谢。Xiao-Li Ping Bao-Fa Sun Lu Wang Wen Xiao Xin Yang Wen-Jia Wang Samir Adhikari Yue Shi Ying Lv Yu-Sheng Chen Xu Zhao Ang Li Ying Yang Ujwal Dahal Xiao-Min Lou Xi Liu Jun Huang Wei-Ping Yuan Xiao-Fan Zhu Tao Cheng Yong-Liang Zhao Xinquan Wang Jannie M Rendtlew Danielsen Feng Liu Yun-Gui Yang 2014Cell Research2014,24,2:244
2Biodiesel production from transesteritication of rapeseed oil using KF/Eu2 O3 as a catalyst 显示文摘Sun H Hu K Lou H Zheng X M 2008Energy Fuels2008,22,:1
3Asymptotic profile of thesteady states for an SIS epidemic patch model显示文摘Allen L J S Bolker B M Lou Y Nevai A L 2007SIAM J Appl Math2007,,67:1
4C-fos-deficient mouse hippocampal CA3 pyramidal neurons exhibit both enhanced basal and kainic acid-induced excitability显示文摘 Zhang J Lou D Chavkin C Xu M 2002Neurosci Lett2002,331,3:1
5Hyperbaric oxygentreatment attenuated the decrease in regional emission tomo-graphy study 显示文摘Lou M Zhang H Wang J 2007Neuroscience2007,146,2:1
6Soy isoflvonoids exhibit in vitro biological acticities of loop diuretics显示文摘Martínez R M Giménez I Lou JM 1998Am J Clin Nutr1998,68,1:1
7Therapeutic window for use of hyperbaric oxygenation in focal transient ischemia in rats显示文摘Lou M Eschenfelder CC Herdegen T 2004Stroke2004,35,2:1
8Highly sensitive WO3 hollow-sphere gas sensors显示文摘Li X L Lou T J Sun X M 2004Inorg Chem2004,43,17:1
9Clinical significance of detecting sur- vivin- expressing circulating cancer ceils in patients with non - small cell lung cancer显示文摘YIE S M LOU B YE S R 2009Lung Cancer2009,63,2:1
10Static and dynamic analysis for contactor with a new type of permanent magnet actuator显示文摘Rong M Z Lou J Y Liu Y Y 2006IEICE Transactions on Electronics2006,89,8:1
11Asymptotic profile of thesteady states ibr an SI~ epidemic reaction-diffusion model显示文摘Allen L J S Bolker B M Lou Y Nevai A L 2008Discr Cont Dyn Sys A2008,,21:1
12In vivo Bcl-2 onlogene neuronal expression in the rat spinal cord显示文摘 Lenke LG Obrien M 1998Spine1998,23,5:1
13The opposing effect of hypoxia- inducible factor-2alpha on expression of telomerase reverse transcriptase 显示文摘Lou F Chen X Jalink M 2007Mol Cancer Res2007,5,8:1
14Dynamic Multi-sensor Data Fusion System for Intelligent Robots 显示文摘Lou R C Lin M Scherp P S 1988IEEE Journal of Robotics and Automation1988,4,4:1
15Local Phase Decomposi- tion as a Cause of Polarization Fatigue in Ferroelectrie Thin Film 显示文摘Lou X J Zhang M Redfern SAT 2006Physical Review Letters2006,97,17:1
16Vertebrobasilar dilatative arteriopathy dolichoectasia显示文摘Lou M Caplan LR 2010Ann N Y Acad Sci2010,1184,:1
17Innovative Soft Soil Sta- bilization Using Simultaneous High-Vacuum Dewatering and Dy- namic Compaction 显示文摘Chang D T T Lou X M Xu S L 2010Transportation Research Record : Journal of the Transportation Research Board2010,,1:1
18Numerical simulation of steady and unsteady aluminum profile extrusion processes using fi- nite volume method 显示文摘Lou S M Zhao G Q Wang R 2008Engineering Computations2008,25,6:1
19Alkali and alkaline earth metallic (AAEM) species leaching and Cu( II ) sorption by biochar 显示文摘LI M LOU Z WANG Y 2015Chemosphere2015,119,1:1
20Adenovirus-mediated gene trans- fer into tendon and tendon sheath显示文摘Lou J Manske PR Aoki M et a l 1996J Orthop Res1996,14,4:1
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