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| 1 | Mammalian WTAP is a regulatory subunit of the RNA N6-methyladenosine methyltransferase显示文摘包含 methyltransferase 建筑群的象 3 一样的 methyltransferase (METTL3 ) 催化 N6-methyladenosine (m6A ) 形成,一个新奇 epitranscriptomic 标记;然而,这建筑群的性质仍然保持大部分未知。这里,我们报导人的 m6A methyltransferase 建筑群, Wilm 的肿瘤 1 伙伴蛋白质(WTAP ) 和象 14 一样的 methyltransferase (METTL14 ) 的二个新部件。WTAP 与 METTL3 和 METTL14 交往,并且为他们的本地化被要求进在 vivo 与处理因素的 pre-mRNA 并且为 m6A methyltransferase 的催化活动充实的原子点缀。RNA 的多数在 vivo 由 WTAP 和 METTL3 跳了代表包含一致 m6A 主题的 mRNAs。当 WTAP 不在时, METTL3 的 RNA 有约束力的能力强烈被减少,建议 WTAP 可以工作调整到 mRNA 目标的 m6A methyltransferase 建筑群的招募。而且,在有 photoactivatable-ribonucleoside-enhanced crosslinking 和 immunoprecipitation (同等片断) 的联合的 transcriptomic 分析说明那 WTAP 和 METTL3 调整涉及抄写并且 RNA 处理的基因拼接的表示和选择。在 zebrafish 胚胎的调停 Morpholino 的击倒的指向 WTAP 或 METTL3 引起了织物区别缺点并且增加了 apoptosis。这些调查结果提供 WTAP 可以在 m6A methyltransferase 建筑群作为一个规章的子单元工作并且在 RNA 的 epitranscriptomic 规定起一个关键作用的充分证据新陈代谢。 | Xiao-Li Ping Bao-Fa Sun Lu Wang Wen Xiao Xin Yang Wen-Jia Wang Samir Adhikari Yue Shi Ying Lv Yu-Sheng Chen Xu Zhao Ang Li Ying Yang Ujwal Dahal Xiao-Min Lou Xi Liu Jun Huang Wei-Ping Yuan Xiao-Fan Zhu Tao Cheng Yong-Liang Zhao Xinquan Wang Jannie M Rendtlew Danielsen Feng Liu Yun-Gui Yang | 2014 | Cell Research2014，24，2： | 244 |
| 2 | New vacuum solar telescope and observations with high resolution显示文摘The New Vacuum Solar Telescope(NVST) is a one meter vacuum solar telescope that aims to observe fine structures on the Sun. The main goals of NVST are high resolution imaging and spectral observations, including measurements of the solar magnetic field. NVST is the primary ground-based facility used by the Chinese solar research community in this solar cycle. It is located by Fuxian Lake in southwest China, where the seeing is good enough to perform high resolution observations. We first introduce the general conditions at the Fuxian Solar Observatory and the primary science cases of NVST. Then, the basic structures of this telescope and instruments are described in detail. Finally, some typical high resolution data of the solar photosphere and chromosphere are also shown. | Zhong Liu Jun Xu Bo-Zhong Gu Sen Wang Jian-Qi You Long-Xiang Shen Ru-Wei Lu Zhen-Yu Jin Lin-Fei Chen Ke Lou Zhi Li Guang-Qian Liu Zhi Xu Chang-Hui Rao Qi-Qian Hu Ru-Feng Li Hao-Wen Fu Feng Wang Men-Xian Bao Ming-Chan Wu Bo-Rong Zhang | 2014 | Research in Astronomy and Astrophysics2014，14，6： | 37 |
| 3 | A Genetic Pathway for Tapetum Development and Function in Arabidopsis显示文摘In anther development, tapetal cells take part in complex processes, including endomitosis and apoptosis (programmed cell death). The tapetum provides many of the proteins, lipids, polysaccharides and other molecules necessary for pollen development. Several transcription factors, including DYT1, TDF1, AMS, MS188 and MS1, have been reported to be essential for tapetum development and function in Arabidopsis thaliana. Here, we present a detailed cytological analysis of knockout mutants for these genes, along with an in situ RNA hybridization experiment and double mutant analysis showing that these transcription factors form a genetic pathway in tapetum development. DYT1, TDF1 and AMS function in early tapetum development, while MS188 and MS1 are important for late tapetum development. The genetic pathway revealed in this work facilitates further investigation of the function and molecular mechanisms of tapetum development in Arabidopsis. | Jun Zhu Yue Lou Xiaofeng Xu Zhong-Nan Yang | 2011 | Journal of Integrative Plant Biology2011，53，11： | 32 |
| 4 | Epidemiological characteristics of thyroid nodules and risk factors for malignant nodules: a retrospective study from 6 304 surgical cases显示文摘 | Huan Qin Wang Kun Lou Fuchen Zhang Li Huang Qingxian Han Yunfeng Sun Hancheng Zhu Lei Lin Peng Song Jun Liu Fuqiang Wang Qian Hou Weikai | 2014 | Chinese Medical Journal2014，，12： | 20 |
| 5 | Role of gut microbiota via the gut-liver-brain axis in digestive diseases显示文摘The gut-brain axis is a bidirectional information interaction system between the central nervous system(CNS) and the gastrointestinal tract, in which gut microbiota plays a key role. The gut microbiota forms a complex network with the enteric nervous system, the autonomic nervous system, and the neuroendocrine and neuroimmunity of the CNS, which is called the microbiota-gut-brain axis. Due to the close anatomical and functional interaction of the gut-liver axis, the microbiota-gut-liver-brain axis has attracted increased attention in recent years. The microbiota-gut-liver-brain axis mediates the occurrence and development of many diseases, and it offers a direction for the research of disease treatment. In this review, we mainly discuss the role of the gut microbiota in the irritable bowel syndrome, inflammatory bowel disease, functional dyspepsia, non-alcoholic fatty liver disease, alcoholic liver disease, cirrhosis and hepatic encephalopathy via the gut-liver-brain axis, and the focus is to clarify the potential mechanisms and treatment of digestive diseases based on the further understanding of the microbiota-gut-liver-brain axis. | Jian-Hong Ding Zhe Jin Xiao-Xu Yang Jun Lou Wei-Xi Shan Yan-Xia Hu Qian Du Qiu-Shi Liao Rui Xie Jing-Yu Xu | 2020 | World Journal of Gastroenterology2020，26，40： | 13 |
| 6 | The functional analysis of OsTDF1 reveals a conserved genetic pathway for tapetal development between rice and Arabidopsis显示文摘在花药开发期间, tapetum 为花粉开发提供材料和营养素。在 Arabidopsis,几个抄写因素被识别了为 tapetal 开发和功能形成一条基因小径(DYT1TDF1AMSMS188MS1 ) 。在 TAPETAL 开发和 FUNCTION1 (TDF1 ) 的有缺陷者是 R2R3 MYB 家庭的一个成员并且为在 Arabidopsis 的早 tapetum 开发是必要的。这里,我们在米饭描绘了 Arabidopsis TDF1 的 ortholog, OsTDF1 (LOC_Os03g18480 ) 。OsTDF1 分享 69 ? 有在 N 终端区域附近的通常认为的 MYB 领域的 AtTDF1 的 % 氨基酸顺序身份。RT-PCR 并且在 situ 杂交表演,那 OsTDF1 明确地在米饭花药的 tapetal 房间被表示。在 Arabidopsis tdf1 异种的 OsTDF1 的表达式恢复它的富饶,建议这个相当或相同的事物能完成在 Arabidopsis 的 TDF1 的正常函数。ostdf1 大美人异种展出男性无菌的显型。它的 tapetal 房间展出类似于 Arabidopsis tdf1 异种的 vacuolated 和 hypertrophic 显型。终端 deoxynucleotidyl 当为 tapetum 的一个必要管理者规划了房间死亡,把试金标记的调停 transferase 的 dUTP 刻痕结束揭示了 OsTDF1 行为。qRT-PCR 分析表明 OsTDF1 UDT1 下游地行动,建议为 tapetum 开发的基因小径通常在米饭和 Arabidopsis 之间被保存并且在米饭的 TDR, EAT1, OsMYB103 和 PTC1 在上游。 | Ci-Feng Cai Jun Zhu Yue Lou Zong-Li Guo Shuang-Xi Xiong Ke Wang Zhong-Nan Yang | 2015 | Science Bulletin2015，60，12： | 13 |
| 7 | Arabidopsis AT-hook Protein TEK Positively Regulates the Expression of Arabinogalactan Proteins for Nexine Formation显示文摘Nexine 是花粉墙的保存的层。我们以前报导 nexine 层在经由在钩(TEK ) 基因的 Arabidopsis TRANSPOSABLE 元素 SILENCING 的猛烈异种是不在的。在这研究,我们在花粉开发调查了 TEK 的分子的规章的功能并且识别了作为 TEK 的直接目标编码 Arabinogalactan 蛋白质(AGP ) 的基因,它为 nexine 形成是必要的。tek 和 TEK-SRDX 的 Phenotypic 类似转基因的线建议 TEK 在花药开发在 transcriptional 激活起一个作用。Microarray 分析在 tek 识别了 661 基因 downregulated 的一个总数,包括编码 AGP, AGP6, AGP11, AGP23,和 AGP40 的四基因。Electrophoretic 活动性移动试金证明 TEK 能直接绑原子矩阵附件区域(3 月) 和 AGP6 的倡导者。PCR 分析跟随的染色质 immunoprecipitation 证明 TEK 在四 AGP 基因的倡导者被充实。TEK 倡导者在 tek 驾驶的 AGP6 的表示部分救了 nexine 形成和植物富饶。这些结果显示 TEK 直接在花药调整 AGP 表示控制 nexine 层形成。我们也建议 glycoproteins 可能是在花粉墙中的 nexine 层的必要部件。 | Qi-Shi dia Jun Zhu Xiao-Feng Xu Yue Lou Zhan-Lin Zhang Zhi-Ping Zhang Zhong-Nan Yang | 2015 | Molecular Plant2015，8，2： | 10 |
| 8 | Downregulation of lncRNA AFAP1-AS1 by oridonin inhibits the epithelial-to-mesenchymal transition and proliferation of pancreatic cancer cells显示文摘Recent studies have demonstrated that the expression of the long non-coding RNA(lncRNA)AFAP1-AS1 in pancreatic cancer is negatively correlated with survival and prognosis.However,the effects of oridonin and lncRNA AFAP1-AS1 on the epithelial-to-mesenchymal transition(EMT)and migration of pancreatic cancer cells have not been fully elucidated.Surgery is the only potentially curative method for pancreatic cancer,but postoperative recurrence and metastasis are common.The aim of the present study was to assess the effect of oridonin and lncRNA AFAP1-AS1 silencing on pancreatic cancer cells.The pancreatic cancer cell lines BxPC-3 and PANC-1 cells were transfected with siAFAP1-AS1 and its negative control(siNC).After that,oridonin was used to treat the siAFAP1-AS1-transfected cells.The expression of lncRNA AFAP1-AS1 was downregulated in the pancreatic cancer cell lines BxPC-3 and PANC-1.The apoptosis and cell cycle progression of pancreatic cancer cells were evaluated by flow cytometry and Hoechst 33258 staining.Metastasis and invasion of BxPC-3 and PANC-1 cells were detected by transwell migration assay,real-time cell analysis,and western blot analysis.Cells were transfected with the lentiviral siAFAP1-AS1 and siNC,and tumorigenesis was evaluated in BALB/C nude mice.Immunohistochemical examination was used to verify the effects of oridonin and siAFAP1-AS1 on pancreatic cancer.The results demonstrated that the combination of oridonin and siAFAP1-AS1 inhibited pancreatic cancer cell proliferation,induced apoptosis,arrested cell cycle progression,prevented the migration,regulated EMT-related protein expression in BxPC-3 and PANC-1 cells,and inhibited pancreatic cancer cell tumorigenicity and EMT in nude mice. | Songmei Lou Jian Xu Bili Wang Shuquan Li Jun Ren Zhengjun Hu Bin Xu Feng Luo | 2019 | Acta Biochimica et Biophysica Sinica2019，51，8： | 10 |
| 9 | THE HAUSDORFF MEASURE OF GENERALIZED SIERPINSKI CARPETS显示文摘Let 0 | Zhu Yucan Lou Jun | 2000 | Analysis in Theory and Applications2000，16，2： | 9 |
| 10 | Analysis of Health Service Utilization and its Influencing Factors among Patients with Pneumoconiosis in China显示文摘Pneumoconiosis,an interstitial lung disease that occurs from breathing in certain kinds of damaging dust particles,is a major occupational disease in China.Patients diagnosed with occupational pneumoconiosis can avail of free medical treatment,whereas patients without a diagnosis of occupational diseases cannot not claim free medical treatment in most provinces from the government before 2019.This study aimed to analyze the priority of medical facility selection and its influencing factors among patients with pneumoconiosis. | WANG Huan Qiang JIA Jun Lin JIANG Zhao Qiang JIN Qi LI Dong Xia LING Rui Jie LI Ying CUI Ping CHEN Gang ZHAO Hong Yu LI Yan WEN Ke LYU Xiang Pei LOU Jian Lin LI Tao | 2021 | Biomedical and Environmental Sciences2021，34，1： | 9 |
| 11 | Analysis of ESTs and gene expression patterns of the posterior silkgland in the fifth instar larvae of silkworm, Bombyx mori L.显示文摘The fibroin gene expression pattern and regulation of the posterior silkgland were studied by means of expressed sequence tags (ESTs) using the first and fifth day larvae of the fifth instar of silkworm, Bombyx mori L (strain: C 108). The results showed that there were 911 repetitive ESTs and 1950 single sequences (Singlets) among total 2861 consentient sequences, which were spliced. 1335 sequences were identified and the other 1526 were unknown. 5560 sequences (55.89%) in the posterior silkgland cell of the silkworm were new ESTs without homology with EST data published by Mita et al. The number of repetitive ESTs and single sequences from the first day larvae of the fifth instar was double more than that of the fifth day of the same instar in the silkworms. The unigenes which were more than 50 in repetitive EST size (contig size) came to only about 0.5% in total consentient sequences. There were significant differences between gene expression frequencies, and expressed genes were related to fibroin synthesis and its secretion and fibroin composition. Comparing the fifth day with the first day of the fifth instar, the genes-expressed quantity of fibroin heavy-chain gene was 18 fold higher, fibroin light-chain gene 9 fold and fibroin P52 gene 8 fold. 508 genes functioned for cellular component and 315 for enzyme after function tracing. These results implied that the gene expression of the first day was mainly for preparation for fibroin synthesis except for the growth of silkgland cells, and the gene expression of the fifth day of the fifth instar was mainly for synthesizing and excreting fibroin. Because the ratio of heavy chain, light chain and p25 of fibroin was not 6:6:1 as theoretically expected, or its special H-chain structure, the H-chain gene was not easy to detect through EST technique. Most of genes among total 2861 consentient sequences functioned for fibroin synthesis and secretion. This suggested the fibroin synthesis and secretion procedure of the posterior silkgland was more complex than the knowledge we have. | ZHONG Boxiong, YU Yingpo, XU Yusong, YU Hong, LU Xingmeng, MIAO Yungen, YANG Jun, XU Hao, HU Songnian & LOU Chengfu College of Animal Sciences, Zhejiang University, Hangzhou 310029, China Hangzhou Huada Gene Research and Development Center, Southern Base of Genomic Information, Chinese Academy of Sciences, Hangzhou 310007, China | 2005 | Science China(Life Sciences)2005，48，1： | 8 |
| 12 | Stress area of the mandibular alveolar mucosa under complete denture with linear occlusion at lateral excursion显示文摘背景在侧面的旅行还原剂期间摇和一颗装载完全的假牙(CD ) 的不稳定性在假牙底下面的适用的区域,引起局部性的高应力集中。这能导致 mucosal 温柔,溃疡,和牙槽的骨头再吞,并且线性吸藏设计到侧面的力量在假牙上并且到施加了的减少保证假牙稳定性。但是线性 occlusal CD (LOCD ) 和解剖 occlusal CD (AOCD ) 的适用的区域怎么不同,不被知道。学习是在侧面的 excursion.Methods 在 LOCD 和 AOCD 下面在 mandible 的牙槽的 mucosa 分析并且比较高、低的垂直忍受压力的区域的分布的这的目的计算机化断层摄影术( CT ),有限元素分析被用来与严重剩余建立一个无齿的下颚和上颚的三维的模型山脉再吞。这些模型由颚、 mandible 的骨头结构, mucosa,和 LOCD 或 AOCD 组成。上颚的侧面的旅行运动被模仿,在在两 mandible 的 CD 下面的 mucosa 的垂直忍受压力的区域在工作方面上用 ANSYS 7.0 .Results 被分析,高度忍受压力(到 -0.1 Mpa 的 -0.07 )在 LOCD 下面的区域在 AOCD 下面在侧面的旅行期间是比那小的,当时媒介忍受压力(到 -0.07 Mpa 的 -0.03 )在 LOCD 下面的区域是1.33褶层那在 AOCD 下面。在 LOCD 下面的非工作的方面上的中等忍受压力的区域是 2.4 褶层那在 AOCD 下面。因此,在 LOCD 下面的全面中等垂直忍受压力的区域是 20% 比那大在 AOCD.Conclusions 下面在侧面的旅行期间,在 mandible 的 LOCD 下面的中等垂直忍受压力的区域更大,高垂直的忍受压力的区域在 AOCD 下面是比那小的。因此,在 LOCD 下面的垂直压力在 AOCD 下面比那更均匀地并且在一个更宽的区域上被散布,从而改善的假牙稳定性。 | LU Ya-lin LOU Hang-di RONG Qi-guo DONG Jian XU Jun | 2010 | Chinese Medical Journal2010，，7： | 8 |
| 13 | Do vehicular emissions dominate the source of C6–C8 aromatics in the megacity Shanghai of eastern China?显示文摘The characteristic ratios of volatile organic compounds(VOCs) to i-pentane, the indicator of vehicular emissions, were employed to apportion the vehicular and non-vehicular contributions to reactive species in urban Shanghai. Two kinds of tunnel experiments, one tunnel with more than 90% light duty gasoline vehicles and the other with more than 60% light duty diesel vehicles, were carried out to study the characteristic ratios of vehicle-related emissions from December 2009 to January 2010. Based on the experiments, the characteristic ratios of C6–C8aromatics to i-pentane of vehicular emissions were 0.53 ± 0.08(benzene), 0.70 ± 0.12(toluene),0.41 ± 0.09(m,p-xylenes), 0.16 ± 0.04(o-xylene), 0.023 ± 0.011(styrene), and 0.15 ± 0.02(ethylbenzene), respectively. The source apportionment results showed that around 23.3% of C6–C8 aromatics in urban Shanghai were from vehicular emissions, which meant that the non-vehicular emissions had more importance. These findings suggested that emission control of non-vehicular sources, i.e. industrial emissions, should also receive attention in addition to the control of vehicle-related emissions in Shanghai. The chemical removal of VOCs during the transport from emissions to the receptor site had a large impact on the apportionment results. Generally, the overestimation of vehicular contributions would occur when the VOC reaction rate constant with OH radicals(k OH) was larger than that of the vehicular indicator, while for species with smaller k OH than the vehicular indicator, the vehicular contribution would be underestimated by the method of characteristic ratios. | Hongli Wang Qian Wang Jianmin Chen Changhong Chen Cheng Huang Liping Qiao Shengrong Lou Jun Lu | 2015 | Journal of Environmental Sciences2015，27，1： | 7 |
| 14 | An-Luo-Hua-Xian Pill Improves the Regression of Liver Fibrosis in Chronic Hepatitis B Patients Treated with Entecavir显示文摘Background and Aims:Chronic hepatitis B(CHB)can cause liver fibrosis and lead to cirrhosis and cancer.As the effectiveness of antiviral therapy to reverse liver fibrosis is limited,We aimed to evaluate the effect of An-Luo-Hua-Xian pill(ALHX)on fibrosis regression in CHB patients treated with entecavir(ETV).Methods:Treatment-naïve patients with CHB were randomly treated with ETV alone or combined with ALHX(ETV+ALHX)between October 1,2013 and December 31,2020.Demographic,laboratory,and liver histology data before and after 78 weeks of treatment were collected.The Ishak fibrosis score(F)was used and fibrosis regression required a decrease in F of≥1 after treatment.Results:A total of 780 patients were enrolled,and 394 with a second liver biopsy after treatment were included in the per-protocol population,132 in ETV group and 262 in ETV+ALHX group.After 78 weeks of treatment,the fibrosis regression rate in the ETV+ALHX group was significantly higher than that of the ETV group at baseline F≥3 patients:124/211(58.8%)vs.45/98(45.9%),p=0.035.The percentage of patients with a decreased liver stiffness measurement(LSM)was higher in the ETV+ALHX group:156/211(73.9%)vs.62/98(63.%),p=0.056.Logistic regression analysis showed that ETV combined with ALHX was associated with fibrosis regression[odds ratio(OR)=1.94,p=0.018],and a family history of hepatocellular carcinoma was on the contrary.(OR=0.41,p=0.031).Conclusions:ETV combined with ALHX increased liver fibrosis regression in CHB patients. | Yi-Qi Liu Chi Zhang Jia-Wen Li Li-Hua Cao Zhan-Qing Zhang Wei-Feng Zhao Qing-Hua Shang Da-Zhi Zhang An-Lin Ma Qing Xie Hong-Lian Gui Guo Zhang Ying-Xia Liu Jia Shang Shi-Bin Xie Jun Li Xu-Qing Zhang Zhi-Qiang Zou Yu-Ping Chen Zong Zhang Ming-Xiang Zhang Jun Cheng Fu-Chun Zhang Li-Hua Huang Jia-Bin Li Qing-Hua Meng Hai-Bin Yu Yu-Qiang Mi Yan-Zhong Peng Zhi-Jin Wang Li-Ming Chen Fan-Ping Meng Wan-Hua Ren Lang Bai Yi-Lan Zeng Rong Fan Xian-Zhi Lou Wei-Feng Liang Hui Liu Hui Zhuang Hong Zhao Gui-Qiang Wang | 2023 | Journal of Clinical and Translational Hepatology2023，11，2： | 7 |
| 15 | Elimination of misrun and gas hole defects of investment casting TiAl alloy turbocharger based on numerical simulation and experimental study显示文摘Casting technology of thin-wall TiAl alloy turbochargers was studied by investment casting and numerical simulation.Misruns and gas holes were the main defects observed in preliminary work due to the poor fluidity of alloy,and to gas entrapment.In order to eliminate these defects,cast parameters,such as centrifugal rotation rate and mould preheating temperature,were optimized by numerical simulation,meanwhile,the structure of the shell mould was optimized to improve the filling capacity of TiAl alloy.Pouring experiments were carried out by vacuum induction melting furnace equipped with a water-cooled copper crucible based on the above optimization.The quality of the TiAl alloy casting was analyzed by fluorescent penetrant inspection and X-ray detection.The results show that a centrifugal rotation rate of 200 rpm,mould preheating temperature of 600°C,shell preparation through organic fiber addition can dramatically improve the mould filling capacity,and integrated turbochargers were finally prepared. | Jun Zhao Zhi-yong Zhang Shi-bing Liu Kun Shi Chun-ling Bao Zhao-sheng Ning Ping Yan Lei Wang Yan-chun Lou | 2020 | China Foundry2020，17，1： | 6 |
| 16 | Efficacy of structured education in patients with type 2 diabetes mellitus receiving insulin treatment (结构化教育对接受胰岛素治疗的2型糖尿病患者的效果)显示文摘 | Xiao Hui Guo Li Nong Ji Ju Ming Lu Jie Liu Qing Qing Lou Jing Liu Li Shen Ming Xia Zhang Xiao Feng Lv Ming Jun Gu | 2014 | Journal of Diabetes2014，，4： | 5 |
| 17 | Preparation of a novel PAN/cellulose acetate-Ag based activated carbon nanofiber and its adsorption performance for low-concentration SO_2显示文摘Polyacrylonitrile(PAN), PAN/cellulose acetate(CA), and PAN/CA-Ag based activated carbon nanofiber(ACNF) were prepared using electrostatic spinning and further heat treatment. Thermogravimetry–differential scanning calorimetry(TG–DSC) analysis indicated that the addition of CA or Ag did not have a significant impact on the thermal decomposition of PAN materials but the yields of fibers could be improved. Scanning electron microscopy(SEM) analysis showed that the micromorphologies of produced fibers were greatly influenced by the viscosity and conductivity of precursor solutions. Fourier transform infrared spectroscopy(FT-IR) analysis proved that a cyclized or trapezoidal structure could form and the carbon scaffold composed of C=C bonds appeared in the PAN-based ACNFs. The characteristic diffraction peaks in X-ray diffraction(XRD) spectra were the evidence of a turbostratic structure and silver existed in the PAN/CA-Ag based ACNF. Brunner–Emmett–Teller(BET) analysis showed that the doping of CA and Ag increased surface area and micropore volume of fibers; particularly, PAN/CA-Ag based ACNF exhibited the best porosity feature. Furthermore, SO2 adsorption experiments indicated that all the three fibers had good adsorption effects on lower concentrations of SO2 at room temperature; especially, the PAN/CA-Ag based ACNF showed the best adsorption performance, and it may be one of the most promising adsorbents used in the fields of chemical industry and environment protection. | Yan-bo Wu Jun Bi Ting Lou Tie-ben Song Hong-quan Yu | 2015 | International Journal of Minerals,Metallurgy and Materials2015，22，4： | 5 |
| 18 | Synthesis of large-scale atomic-layer SnS2 through chemical vapor deposition显示文摘因为他们的 ultrathin 厚度和潜在的应用,金属 dichalcogenides 的二维的层在电子学和光电子吸引了许多注意。有 ~ 的乐队差距的单层 SnS 2, 2.6 eV,有用硫的二原子层和锡的一原子层做的一个八面的格子。到日期为止,在那里被限制了作为一个半导体在大规模、高质量的 SnS 2 的生长上报导原子层和他们的性质的调查。这里,我们与一种大水晶尺寸和一致性报导原子层的 SnS 2 的化学蒸汽免职(CVD ) 生长。另外,层的数字能被改变生长时间从单层改变到很少层并且到体积。扫描传播电子显微镜学被用来分析原子结构并且表明叠不同的层的 poly 类型的 2H。结果的 SnS 2 晶体象 150% 一样高与外部量效率被用作一个光电探测器,建议为 optoelectronic 应用的诺言。 | Gonglan Ye Yongji Gong Sidong Lei Yongmin He Bo Li Xiang Zhang Zehua Jin Liangliang Dong Jun Lou Robert Vajtai Wu Zhou Pulickel M. Ajayan | 2017 | Nano Research2017，10，7： | 4 |
| 19 | De novo assembly of a Tibetan genome and identification of novel structural variants associated with high-altitude adaptation显示文摘Structural variants(SVs) may play important roles in human adaptation to extreme environments such as high altitude but have been under-investigated. Here, combining long-read sequencing with multiple scaffolding techniques, we assembled a high-quality Tibetan genome(ZF1), with a contig N50 length of 24.57 mega-base pairs(Mb) and a scaffold N50 length of 58.80 Mb. The ZF1 assembly filled 80 remaining N-gaps(0.25 Mb in total length) in the reference human genome(GRCh38). Markedly, we detected17 900 SVs, among which the ZF1-specific SVs are enriched in GTPase activity that is required for activation of the hypoxic pathway. Further population analysis uncovered a 163-bp intronic deletion in the MKL1 gene showing large divergence between highland Tibetans and lowland Han Chinese. This deletion is significantly associated with lower systolic pulmonary arterial pressure, one of the key adaptive physiological traits in Tibetans. Moreover, with the use of the high-quality de novo assembly, we observed a much higher rate of genome-wide archaic hominid(Altai Neanderthal and Denisovan) shared non-reference sequences in ZF1(1.32%–1.53%) compared to other East Asian genomes(0.70%–0.98%),reflecting a unique genomic composition of Tibetans. One such archaic hominid shared sequence-a662-bp intronic insertion in the SCUBE2 gene-is enriched and associated with better lung function(the FEV1/FVC ratio) in Tibetans. Collectively, we generated the first high-resolution Tibetan reference genome, and the identified SVs may serve as valuable resources for future evolutionary and medical studies. | Ouzhuluobu Yaoxi He Haiyi Lou Chaoying Cui Lian Deng Yang Gao Wangshan Zheng Yongbo Guo Xiaoji Wang Zhilin Ning Jun Li Bin Li Caijuan Bai Baimakangzhuo Gonggalanzi Dejiquzong Bianba Duojizhuoma Shiming Liu Tianyi Wu Shuhua Xu Xuebin Qi Bing Su | 2020 | National Science Review2020，7，2： | 4 |
| 20 | Lijiang 2.4-meter Telescope and its instruments显示文摘The Lijiang 2.4-meter Telescope(LJT), the largest common-purpose optical telescope in China,has been available to the worldwide astronomical community since 2008. It is located at the Gaomeigu site,Lijiang Observatory(LJO), in the southwest of China. The site has very good observational conditions.During its 10-year operation, several instruments have been equipped on the LJT. Astronomers can perform both photometric and spectral observations. The main scientific goals of LJT include recording photometric and spectral evolution of supernovae, reverberation mapping of active galactic nuclei, investigating the physical properties of binary stars and near-earth objects(comets and asteroids), and identification of exoplanets and all kinds of transients. Until now, the masses of 41 high accretion rate black holes have been measured, and more than 168 supernovae have been identified by the LJT. More than 190 papers related to the LJT have been published. In this paper, the general observation conditions of the Gaomeigu site is introduced at first. Then, the structure of the LJT is described in detail, including the optical, mechanical, motion and control system. The specification of all the instruments and some detailed parameters of the YFOSC is also presented. Finally, some important scientific results and future expectations are summarized. | Chuan-Jun Wang Jin-Ming Bai Yu-Feng Fan Ji-Rong Mao Liang Chang Yu-Xin Xin Ju-Jia Zhang Bao-Li Lun Jian-Guo Wang Xi-Liang Zhang Mei Ying Kai-Xing Lu Xiao-Li Wang Kai-Fan Ji Ding-Rong Xiong Xiao-Guang Yu Xu Ding Kai Ye Li-Feng Xing Wei-Min Yi Liang Xu Xiang-Ming Zheng Yuan-Jie Feng Shou-Sheng He Xue-Li Wang Zhong Liu Dong Chen Jun Xu Song-Nian Qin Rui-Long Zhang Hui-Song Tan Zhi Li Ke Lou Jian Li Wei-Wei Liu | 2019 | Research in Astronomy and Astrophysics2019，19，10： | 4 |
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