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| 1 | 非诺贝特治疗与2型糖尿病患者长期心血管病风险的关系显示文摘2型糖尿病患者心血管病风险高,部分原因在于高三酰甘油和低高密度脂蛋白胆固醇血症。而在他汀类药物治疗基础上,加强降低三酰甘油治疗,能否降低这种风险尚不清楚。该研究的目的是在使用他汀类药物治疗的2型糖尿病患者中,确定非诺贝特能否降低心血管病风险。 | 刘莉 叶鹏 Elam MB Ginsberg HN Lovato LC Corson M Largay J Leiter LA Lopez C O'Connor PJ Sweeney ME Weiss D Friedewald WT Buse JB Gerstein HC Probstfield J Grimm R Ismail-Beigi F Goff DC Jr Fleg JL Rosenberg Y Byington RP ACCORDION study investigators | 2017 | 中华高血压杂志2017,25,6: | 7 |
| 2 | Multimodality functional imaging using DW-MRI and 18F-FDG-PET/CT during radiation therapy for human papillomavirus negative head and neck squamous cell carcinoma: Meixoeiro Hospital of Vigo Experience显示文摘AIM To noninvasively investigate tumor cellularity measured using diffusion-weighted magnetic resonance imaging(DW-MRI) and glucose metabolism measured by 18 Flabeled fluorodeoxyglucose positron emission tomography/computed tomography(18F-FDG-PET/CT) during radiation therapy(RT) for human papillomavirus negative(HPV-) head and neck squamous cell carcinoma(HNSCC).METHODS In this prospective study, 6 HPV- HNSCC patients underwent a total of 34 multimodality imaging examinations(DW-MRI at 1.5 T Philips MRI scanner [(n = 24) pre-, during-(2-3 wk), and post-treatment(Tx), and 18F-FDG PET/CT pre- and post-Tx(n = 10)]. All patients received RT. Monoexponential modeling of the DW-MRI data yielded the imaging metric apparent diffusion coefficient(ADC) and the mean of standardized uptake value(SUV) was measured from 18F-FDG PET uptake. All patients had a clinical follow-up as the standard of care and survival status was documented at 1 year.RESULTS There was a strong negative correlation between the mean of pretreatment ADC(ρ =-0.67, P = 0.01) and the pretreatment 18F-FDG PET SUV. The percentage(%) change in delta(?) ADC for primary tumors and neck nodal metastases between pre- and Wk2-3 Tx were as follows: 75.4% and 61.6%, respectively, for the patient with no evidence of disease, 27.5% and 32.7%, respectively, for those patients who were alive with disease, and 26.9% and 7.31%, respectively, for those who were dead with disease.CONCLUSION These results are preliminary in nature and are indicative, and not definitive, trends rendered by the imaging metrics due to the small sample size of HPV- HNSCC patients in a Meixoeiro Hospital of Vigo Experience. | David Aramburu Núnez Antonio Lopez Medina Moisés Mera Iglesias Francisco Salvador Gomez Abhay Dave Vaios Hatzoglou Ramesh Paudyal Alfonso Calzado Joseph O Deasy Amita Shukla-Dave Victor M Munoz | 2017 | World Journal of Radiology2017,9,1: | 2 |
| 3 | Global kinetic evaluation during the reduction of C0WO4with methane for the production of hydrogen显示文摘 | De Los Rios Castillo T Salinas G J Lopez O A | 2013 | International Journal of Hydrogen Energy2013,38,12: | 1 |
| 4 | He- patic angiosarcoma: case report and review of literature 显示文摘 | Poggi Maehuca L Ibarra Chirinos O Lopez Del Aguila J | 2012 | Rev Gastroenterol Peru2012,32,3: | 1 |
| 5 | The relationship a- mong cardiovascular risk factors, diet patterns, alcohol consump- tion, and ethnicity among women aged 50 years and older显示文摘 | LOPEZ E P RICE C WEDDLE D O | 2008 | J Am Diet Assoe2008,108,2: | 1 |
| 6 | CVD growth of carbon nanotubes on catalyst patterns generated with AFM lithography显示文摘 | Cervantez G O Morales G R Lopez J O | 2007 | Journal of Materials Sceiece: Materials in Electronics2007,18,11: | 1 |
| 7 | Suppressors of cytokine signalin regulate angiotensin II-activated Janus kinase-signal transducers and activators of transcription pathway in renal cells显示文摘 | HEMANDEZ VARGAS P LOPEZ FRANCO O SANJUAN G | 2005 | J Am Soc Nephrol2005,16,6: | 1 |
| 8 | Use of nisin and other baeteriocins for preservation of dairy products 显示文摘 | Sobrino Lopez A Martm-Belloso O | 2008 | International Dairy Journal2008,18,: | 1 |
| 9 | Genetic factors influencing high oleic acid content in spanish market-type peanut cultivars 显示文摘 | Lopez Y Nadaf H L Smith O D | 2000 | Crop Sci2000,41,: | 1 |
| 10 | Real-time DeformableModels for Surgery Simulation: A Survey显示文摘 | Meier U Lopez O Monserrat C | 2005 | Computer Methods and Programs in Biomedicine2005,77,3: | 1 |
| 11 | The Denavit and Hartenberg approach applied to evaluate the consequences in the tool tip position of geometrical errors in five-axis milling centres 显示文摘 | LAMIKIZ A LOPEZ DE LACALLE L N OCERIN O | 2008 | Int J Adv Manuf Technol2008,37,: | 1 |
| 12 | Prediction of psychosis onset in Alzheimer disease: the role of cognitive impairment, depressive symptoms, and further evidence for psychosis subtypes 显示文摘 | Wilkosz P Miyahara S Lopez O | 2006 | Am J Geriatr Psychiatry2006,14,: | 1 |
| 13 | Quality prediction nf resistance spot welding joints of 304 austenitic stainless steel 显示文摘 | MARTIN O DE TIEDRA P LOPEZ M | 2009 | Materials & Design2009,30,1: | 1 |
| 14 | Variability of a three-dimensional finite element model constructed using magnetic resonance images of a knee for joint contact stress analysis显示文摘 | Li G Lopez O Rubash H | 2001 | J Biomech Eng2001,123,4: | 1 |
| 15 | The influence of temperature and seawater composition on calcite crystal growth mechanisms and kinetics: Implications for Mg incorporation in calcite lattice 显示文摘 | Lopez O Zuddas P Faivre D | 2009 | Geochimica et Cosmochimica Acta2009,73,2: | 1 |
| 16 | Utilization of oxygen uptake rate to assess the role of glucose and glutamine in the metabolism of infected insect cell cultures显示文摘 | Palomares L A Lopez S Ramirez O T | 2004 | Biochemical Engineering Journal2004,19,1: | 1 |
| 17 | Role of neutralizing antibodies in PRRSV protective immunity显示文摘 | Lopez O J Osorio F A | 2004 | Veterinary Immunology and Immunopathology2004,,102: | 1 |
| 18 | Phylogeny and classification of Pinus 显示文摘 | Gernandt D S Lopez G G Garcia S O | 2005 | Taxon2005,54,1: | 1 |
| 19 | Different configurations for the early description of Escherichia coli activity through dynamic speckles显示文摘 | Miquet E E R Lopez L M Alarcon O R C | 2011 | Rev Mex Fis2011,57,5: | 1 |
| 20 | Real-time deformable models for surgery simulation:a survey显示文摘 | MEUER U LOPEZ O MONSEERRANT C | | 0,,03: | 1 |