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| 1 | Elastic Scattering of 7Be on Pb Target显示文摘 | Yang Yanyun Wang Jiansong Wang Qi Huang Meirong Ma Junbing Ma Peng Cao Xiguang Han Jianlong Bai Zhen Jin Shilong Hu Qiang Jin Lei Chen Jiangbo Zhang Xueying Chen Ruofu Hu Zhengguo Xu Shiwei Zhen Chuan Xu Zhiguo Xu Hushan Duan Liming Sun Zhiyu Chen Zhiqiang He Jianjun Li Songlin Lei Xiangguo Fu Fen Zhang Xueheng Yuan Xiaohua Du Chengming Yan Xinshuang Hu Jun Tang Shuwen Ye Ruiping Yang Kun Shi Fudong Zhang Wei Chen Ze Li Long Xu Xing Liu Longxiang Zhang Liyong Lin Qingyun Gou Boxing Xu Ge Zhou Xionghong Zhang Yuhu Xiao Guoqing | 2011 | IMP & HIRFL Annual Report2011，，1： | 4 |
| 2 | TWO NEW OLEANOLIC ACID SAPONINS FROM ASTER YUNNANENSIS显示文摘TWONEWOLEANOLICACIDSAPONINSFROMASTERYUNNANENSIS￥YuSHAO;BingNanZHOU;LongZeLINandGeoffreyA.Cofdell(ShanghaiinstituteofMatstheMe... | Yu SHAO Bing Nan ZHOU Long Ze LIN and Geoffrey A. Cofdell (Shanghai institute of Matsthe Medica, Academic Sinica, Shanghai 2O0031 Program for Collaborative research in the Pharmaceutical Sciences, Coilege of pharmacy,Unlversity of lllinois at Chicago, I | 1994 | Chinese Chemical Letters1994，5，10： | 2 |
| 3 | An Investigation on the Molecular Characteristics and Intracellular Growth Ability among Environmental and Clinical Isolates of Legionella pneumophila in Sichuan Province, China显示文摘Objective To investigate the molecular characteristics and intracellular growth ability of Legionella pneumophila(L. pneumophila) strains from 1989 to 2016 in Sichuan Province, China. Methods Seventy-nine isolates of L. pneumophila were collected from environmental and clinical sources, including cooling towers, hot springs, bath water, fountains, and patients, and identified with 16 S rRNA gene analysis and serum agglutination assay. The isolates were then typed by Sequence-Based Typing(SBT), and Genotyping of forty-two LP1 strains were analyzed by means of multiple-locus VNTR analysis with 8 loci(MLVA-8). All strains were further analyzed for two virulence genes: Legionella vir homologue(lvh) and repeats in structural toxin(rtx A). The intracellular growth ability of 33 selected isolates was determined by examining their interaction with J774 cells. Results All isolates were identified to L. pneumophila including 11 serogroups, among which the main serogroup were LP1, accounting for 54.43%. Thirty-three different sequence types(STs) from five main clonal groups and five singletons were identified, along with 8 different MLVA patterns. Both the lvh and rtx A loci were found in all 79 strains. Thirty isolates showed high intracellular growth ability in J774 cells. Conclusion L. pneumophila is a potential threat to public health, and effective control and prevention strategies are urgently needed. | ZENG Lin Zi LIAO Hong Yu LUO Long Ze HE Shu Sen QIN Tian ZHOU Hai Jian LI Hong Xia CHEN Da Li CHEN Jian Ping | 2019 | Biomedical and Environmental Sciences2019，32，7： | 1 |
| 4 | Exergy analysis of coal - based polygeneration system for power and chemical production 显示文摘 | GAO LIN JIN HONG - GUANG LIU ZE - LONG | 2004 | Energy2004，29，： | 1 |
| 5 | Exergy analysis of coal-based polygeneration system for power and chemical production显示文摘 | Gao Lin Jin Hong guang Liu Ze long | 2004 | Energy2004，29，： | 1 |
| 6 | ASTERYUNNANOSIDE E,A NEW TRITERPENOID SAPONIN FROM ASTER YUNNANENSIS FRANCH显示文摘ASTERYUNNANOSIDE E, A NEW TRITERPENOID SAPONIN FROM ASTER YUNNANENSIS FRANCHASTERYUNNANOSIDEE,ANEWTRITERPENOIDSAPONINFROMASTE... | Yu SHAO Bing Nan ZHOU Long Ze LIN and GeoffFey A. Cordell(Shanghai Institute of Meteria Medica, Academia Sinica, Shanghai 200031)(Program for Collaborative-Research in the Pharmaceutical Sciencec, Department of Medicinal Chemistry and Pharmacognosy, Co | 1994 | Chinese Chemical Letters1994，5，9： | 1 |
| 7 | Analysis of lignan constituents from Schisandra ehinensis by liquid chromatography - el ectroapmy mass spectrometry显示文摘 | Xian - guo He Li - zhi Lian Long - ze Lin | 1997 | Journal of Chromatography A1997，757，： | 1 |
| 8 | A Screening Method for the I- dentification of Glycosylated Flavonoids and Other Phenolic Com- pounds Using a Standard Analytical Approach for All Plant Mate- rials 显示文摘 | Lin Long - Ze Harnly James M | 2007 | Journal of Agricultural and Food Chemistry2007，55，4： | 1 |
| 9 | Autophagy inhibitors increase the susceptibility of KRAS-mutant human colorectal cancer cells to a combined treatment of 2-deoxy-D-glucose and lovastatin显示文摘RAS-driven colorectal cancer relies on glucose metabolism to support uncontrolled growth.However,monotherapy with glycolysis inhibitors like 2-deoxy-D-glucose causes limited effectiveness.Recent studies suggest that anti-tumor effects of glycolysis inhibition could be improved by combination treatment with inhibitors of oxidative phosphorylation.In this study we investigated the effect of a combination of 2-deoxy-D-glucose with lovastatin(a known inhibitor of mevalonate pathway and oxidative phosphorylation)on growth of KRAS-mutant human colorectal cancer cell lines HCT116 and LoVo.A combination of lovastatin(>3.75μM)and 2-deoxy-D-glucose(>1.25 mM)synergistically reduced cell viability,arrested cells in the G2/M phase,and induced apoptosis.The combined treatment also reduced cellular oxygen consumption and extracellular acidification rate,resulting in decreased production of ATP and lower steady-state ATP levels.Energy depletion markedly activated AMPK,inhibited mTOR and RAS signaling pathways,eventually inducing autophagy,the cellular pro-survival process under metabolic stress,whereas inhibition of autophagy by chloroquine(6.25μM)enhanced the cytotoxic effect of the combination of lovastatin and 2-deoxy-D-glucose.These in vitro experiment results were reproduced in a nude mouse xenograft model of HCT116 cells.Our findings suggest that concurrently targeting glycolysis,oxidative phosphorylation,and autophagy may be a promising regimen for the management of RAS-driven colorectal cancers. | Xiao-ming Huang Jia-jun Huang Jing-jing Du Na Zhang Ze Long You Yang Fang-fang Zhong Bo-wen Zheng Yun-fu Shen Zhe Huang Xiang Qin Jun-he Chen Qian-yu Lin Wan-jun Lin Wen-zhe Ma | 2021 | Acta Pharmacologica Sinica2021，42，11： | 1 |
| 10 | Analysis of flavonoids from red clover by liquid chromatography2electrospray mass spectrometry显示文摘 | Xian guo He Long ze Lin Li zhi Lian | 1996 | Journal of Chromatography A1996，755，： | 1 |
| 11 | Quinoline alkaloids from Camptotheca acuminata显示文摘 | Long Ze Lin Geoffrey A Cor Dell | 1989 | Phytochemistry1989，28，4： | 1 |
| 12 | Chromatographicprofiles and identification of new phenolic components of Ginkgo bilo-bal leaves and selected products 显示文摘 | LIN Long - Ze CHEN Pei OZCAN Mustafa | 2008 | Agric Food Chem2008，56，15： | 1 |
| 13 | Advances in nuclear detection and readout techniques显示文摘“A Craftsman Must Sharpen His Tools to Do His Job,”said Confucius.Nuclear detection and readout techniques are the foundation of particle physics,nuclear physics,and particle astrophysics to reveal the nature of the universe.Also,they are being increasingly used in other disciplines like nuclear power generation,life sciences,environmental sciences,medical sciences,etc.The article reviews the short history,recent development,and trend of nuclear detection and readout techniques,covering Semiconductor Detector,Gaseous Detector,Scintillation Detector,Cherenkov Detector,Transition Radiation Detector,and Readout Techniques.By explaining the principle and using examples,we hope to help the interested reader underst and this research field and bring exciting information to the community. | Rui He Xiao‑Yang Niu Yi Wang Hong‑Wei Liang Hong‑Bang Liu Ye Tian Hong‑Lin Zhang Chao‑Jie Zou Zhi‑Yi Liu Yun‑Long Zhang Hai‑Bo Yang Ju Huang Hong‑Kai Wang Wei‑Jia Han Bei Cao Gang Chen Cong Dai Li‑Min Duan Rui‑Rui Fan Fang‑Fa Fu Jian‑Hua Guo Dong Han Wei Jiang Xian‑Qin Li Xin Li Zhuo‑Dai Li Yu‑Tie Liang Shun Liao De‑Xu Lin Cheng‑Ming Liu Guo‑Rui Liu Jun‑Tao Liu Ze Long Meng‑Chen Niu Hao Qiu Hu Ran Xiang‑Ming Sun Bo‑Tan Wang Jia Wang Jin‑Xiang Wang Qi‑Lin Wang Yong‑Sheng Wang Xiao‑Chuan Xia Hao‑Qing Xie He‑Run Yang Hong Yin Hong Yuan Chun‑Hui Zhang Rui‑Guang Zhao Ran Zheng Cheng‑Xin Zhao | 2023 | Nuclear Science and Techniques2023，34，12： | 0 |
| 14 | Author Correction:Autophagy inhibitors increase the susceptibility of KRAS-mutant human colorectal cancer cells to a combined treatment of 2-deoxy-D-glucose and lovastatin显示文摘The authors apologize that in Fig.5d,the western blotting bands of HCT116 cells treated with 2DG(5 mM)and different concentrations of lovastatin were the same as cells treated with lovastatin(10μM)and different concentrations of 2DG,which was misplaced inadvertently.The correct figure is reproduced and presented.The conclusions are not affected by this correction.We sincerely apologize for our mistakes and any inconvenience this might have caused. | Xiao-ming Huang Jia-jun Huang Jing-jing Du Na Zhang Ze Long You Yang Fang-fang Zhong Bo-wen Zheng Yun-fu Shen Zhe Huang Xiang Qin Jun-he Chen Qian-yu Lin Wan-jun Lin Wen-zhe Ma | 2022 | Acta Pharmacologica Sinica2022，43，7： | 0 |
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