|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | Effectsofenvironmenttemperatureoneggproductionandphysiologicalindicesofhens(环境温度对产蛋母鸡性能及某些生理指标的影响)显示文摘 | LIZZ(李震钟) | 1986 | 畜牧与兽医1986,3,: | 1 |
| 2 | Primarystudyoncorre-lationbetweenwheatgrainproteincon-tentandseveralagronomictraits(小麦籽粒蛋白质含量与几个农艺性状相关性的初步研究)[J]显示文摘 | LIZZ(李宗智) | | 河南农业科技0,,: | 1 |
| 3 | Two new species of Stenatkina Young,1986 from China with comparative notes on the female genitalia (Hemiptera:Cicadellidae:Cicadellini)显示文摘 | MengZ H Yang M F LiZZ | 2012 | Zootaxa2012,3231,: | 1 |
| 4 | Local RAS and inflammatory factors are involved in cardiovascular hypertrophy in spontaneously hypertensive rats显示文摘 | Li L Yi-Ming W LiZZ | 2008 | Pharmacol Res2008,58,34: | 1 |
| 5 | Comparisonofclinicalfea-turesandoutcomesofpatientswithacutemyocardialinfarc-tion youngerthan 35 years with those olderthan 65years显示文摘 | HuangJ QianHY LiZZ etal | 2013 | AmJMedSci2013,346,1: | 1 |
| 6 | Flammability characterization and synergistic effects of expandable graphite with magnesium hydroxide in halogen free flame retardant EVA blends显示文摘 | Lizz Qubj | 2003 | Polymer Degradation and Stability2003,81,3: | 1 |
| 7 | Cohort study to assess geographical variation in cholangiocarcinoma treatment in England显示文摘BACKGROUND Outcomes for cholangiocarcinoma(CCA)are extremely poor owing to the complexities in diagnosing and managing a rare disease with heterogenous sub-types.Beyond curative surgery,which is only an option for a minority of patients diagnosed at an early stage,few systemic therapy options are currently recommended to relieve symptoms and prolong life.Stent insertion to manage disease complications requires highly specialised expertise.Evidence is lacking as to how CCA patients are managed in a real-world setting and whether there is any variation in treatments received by CCA patients.AIM To assess geographic variation in treatments received amongst CCA patients in England.METHODS Data used in this cohort study were drawn from the National Cancer Registration Dataset(NCRD),Hospital Episode Statistics and the Systemic Anti-Cancer Therapy Dataset.A cohort of 8853 CCA patients diagnosed between 2014-2017 in the National Health Service in England was identified from the NCRD.Potentially curative surgery for all patients and systemic therapy and stent insertion for 7751 individuals who did not receive surgery were identified as three end-points of interest.Linear probability models assessed variation in each of the three treatment modalities according to Cancer Alliance of residence at diagnosis,and for socio-demographic and clinical characteristics at diagnosis.RESULTS Of 8853 CCA patients,1102(12.4%)received potentially curative surgery.The mean[95%confidence interval(CI)]percentage-point difference from the population average ranged from-3.96(-6.34 to-1.59)%to 3.77(0.54 to 6.99)%across Cancer Alliances in England after adjustment for patient sociodemographic and clinical characteristics,showing statistically significant variation.Amongst 7751 who did not receive surgery,1542(19.9%)received systemic therapy,with mean[95%CI]percentage-point difference from the population average between-3.84(-8.04 to 0.35)%to 9.28(1.76 to 16.80)%across Cancer Alliances after adjustment,again showing the presence of statistically significant variation for some regions.Stent insertion was received by 2156(27.8%),with mean[95%CI]percentage-point difference from the population average between-10.54(-12.88 to-8.20)%to 13.64(9.22 to 18.06)%across Cancer Alliances after adjustment,showing wide and statistically significant variation from the population average.Half of 8853 patients(n=4468)received no treatment with either surgery,systemic therapy or stent insertion.CONCLUSION Substantial regional variation in treatments received by CCA patients was observed in England.Such variation could be due to differences in case-mix,clinical practice or access to specialist expertise. | Sophie Jose Amy Zalin-Miller Craig Knott Lizz Paley Daniela Tataru Helen Morement Mireille B Toledano Shahid A Khan | 2023 | World Journal of Gastrointestinal Oncology2023,15,12: | 0 |
| 8 | Regional variation in routes to diagnosis of cholangiocarcinoma in England from 2006 to 2017显示文摘BACKGROUND Incidence of cholangiocarcinoma(CCA)is rising,with overall prognosis remaining very poor.Reasons for the high mortality of CCA include its late presentation in most patients,when curative options are no longer feasible,and poor response to systemic therapies for advanced disease.Late presentation presents a large barrier to improving outcomes and is often associated with diagnosis via mergency presentation(EP).Earlier diagnoses may be made by Two Week Wait(TWW)referrals through General practitioner(GP).We hypothesise that TWW referrals and EP routes to diagnosis differ across regions in England.AIM To investigate routes to diagnosis of CCA over time,regional variation and influencing factors.METHODS We linked patient records from the National Cancer Registration Dataset to Hospital Episode Statistics,Cancer Waiting Times and Cancer Screening Programme datasets to define routes to diagnosis and certain patient characteristics for patients diagnosed 2006-2017 in England.We used linear probability models to investigate geographic variation by assessing the proportions of patients diagnosed via TWW referral or EP across Cancer Alliances in England,adjusting for potential confounders.Correlation between the proportion of people diagnosed by TWW referral and EP was investigated with Spearman’s correlation coefficient.RESULTS Of 23632 patients diagnosed between 2006-2017 in England,the most common route to diagnosis was EP(49.6%).Non-TWW GP referrals accounted for 20.5%of diagnosis routes,13.8%were diagnosed by TWW referral,and the remainder 16.2%were diagnosed via an‘other’or Unknown route.The proportion diagnosed via a TWW referral doubled between 2006-2017 rising from 9.9%to 19.8%,conversely EP diagnosis route declined,falling from 51.3%to 46.0%.Statistically significant variation in both the TWW referral and EP proportions was found across Cancer Alliances.Age,presence of comorbidity and underlying liver disease were independently associated with both a lower proportion of patients diagnosed via TWW referral,and a higher proportion diagnosed by EP after adjusting for other potential confounders.CONCLUSION There is significant geographic and socio-demographic variation in routes to diagnosis of CCA in England.Knowledge sharing of best practice may improve diagnostic pathways and reduce unwarranted variation. | Amy Zalin-Miller Sophie Jose Craig Knott Lizz Paley Daniela Tataru Helen Morement Mireille B Toledano Shahid A Khan | 2023 | World Journal of Gastroenterology2023,29,24: | 0 |
| 9 | 最后的欢笑显示文摘那是他们最后一次送爸爸去医院,他从病房里打电话给我:“莉莎,医护人员问我有没有在吃什么药。除了伟哥,其他药我都告诉他们了。然后他们就把氧气面罩扣我脸上了。” | Lizz Winstead 张玲 | 2014 | 新东方英语(中英文版)2014,,7: | 0 |