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| 1 | Estimation of Undrained Bearing Capacity for Offshore Soft Foundations with Cyclic Load显示文摘The degradation strength of soils under cyclic loading is studied and a method for deter-mining the cyclic degradation strength with cyclic triaxial tests is given in the paper.Furthermore,a dum-my static method for estimating the undrained bearing capacity for offshore soft foundation under waveloads is developed.It can consider the effect of the difference of cyclic stress for different parts of the foun-dation on both the degradation strength of the foundation soil and the bearing capacity so that the esti-mated result can better reflect the real condition of foundation under cyclic loading.The method can be ap-plied to plane and space problem. | Wang, JH Liu, YF Xing, Y Di, HM | 1998 | China Ocean Engineering1998，13，2： | 18 |
| 2 | Mitochondrial neuronal uncoupling proteins:a target for potential disease-modification in Parkinson’s disease Philip显示文摘This review gives a brief insight into the role of mitochondrial dysfunction and oxidative stress in the converging pathogenic processes involved in Parkinson’s disease(PD).Mitochondria provide cellular energy in the form of ATP via oxidative phosphorylation,but as an integral part of this process,superoxides and other reactive oxygen species are also produced.Excessive free radical production contributes to oxidative stress.Cells have evolved to handle such stress via various endogenous anti-oxidant proteins.One such family of proteins is the mitochondrial uncoupling proteins(UCPs),which are anion carriers located in the mitochondrial inner membrane.There are five known homologues(UCP1 to 5),of which UCP4 and 5 are predominantly expressed in neural cells.In a series of previous publications,we have shown how these neuronal UCPs respond to 1-methyl-4-phenylpyridinium(MPP+;toxic metabolite of MPTP)and dopamine-induced toxicity to alleviate neuronal cell death by preserving ATP levels and mitochondrial membrane potential,and reducing oxidative stress.We also showed how their expression can be influenced by nuclear factor kappa-B(NF-B)signaling pathway specifically in UCP4.Furthermore,we previously reported an interesting link between PD and metabolic processes through the protective effects of leptin(hormone produced by adipocytes)acting via UCP2 against MPP+-induced toxicity.There is increasing evidence that these endogenous neuronal UCPs can play a vital role to protect neurons against various pathogenic stresses including those associated with PD.Their expression,which can be induced,may well be a potential therapeutic target for various drugs to alleviate the harmful effects of pathogenic processes in PD and hence modify the progression of this disease. | WL Ho Jessica WM Ho Hui-Fang Liu Danny HF So Zero HM Tse Koon-Ho Chan David B Ramsden Shu-Leong Ho | 2012 | Translational Neurodegeneration2012，1，1： | 3 |
| 3 | Evaluation of gross tumor size using CT, laF-FDG PET, integrated lSF FDG analysis in non-small cell lung cancer 显示文摘 | Yu HM Liu YF Hou M | 2009 | Eur J Radiol2009，72，10： | 1 |
| 4 | Role of nitric oxide in inflammation mediated neurodegeneration 显示文摘 | Liu B Gao HM Wang JY | 2002 | Annals of the New York Academy of Sciences2002，962，： | 1 |
| 5 | A new strategy to resume p53 in leukemia cell lines retaining wild-type p53显示文摘 | Liu ZJ Xin HM Chen J | 2007 | Leuk Res2007，31，8： | 1 |
| 6 | 显示文摘 | Li LY Shih HM Liu MY | 2001 | J Biol Chem2001，276，27： | 1 |
| 7 | Methodological study of the TdR labelled autoradilgraphy in the arti - cular cavity 显示文摘 | Wang L Liu HM | 1990 | Academic Journal of Second Military Medical Univeusity1990，11，： | 1 |
| 8 | Evaluation of gross tumor size using CT, ^18F-FDG PET, integrated ^18F-FDG PET/CT and pathological analysis in non-small cell lung cancer显示文摘 | Yu HM Liu YF Hou M | 2009 | Eur J Radiol2009，72，1： | 1 |
| 9 | Transarterial embolization of complex cavernous sinus dural arteriovenous fistulae with low- concentration cyanoacrylate 显示文摘 | Liu HM Huang YC Wang YH | 2000 | Neuroradiology2000，42，： | 1 |
| 10 | Computerized classification study on 680 clinical confirmed SARS patients in Xiao Tang Shan Hospital 显示文摘 | Dong J Cao XT Liu ZM Xu HM Li YP Sun X Wang L Zhou YC | 2004 | Chinese Journal of Evidence-Based Medicine2004，4，5： | 1 |
| 11 | Chromosomal aberrations, DNA strand breaks and gene mutations in nasopharyngeal cancer patients undergoing radiation therapy显示文摘 | Cao J Liu Y Sun HM | 2002 | Murat Res2002，504，： | 1 |
| 12 | Gamma knife surgery for cav- ernous hemangiomas: an analysis of 125 patients 显示文摘 | Liu KD Chung WY Wu HM | 2005 | J Neurosurg2005，102，1： | 1 |
| 13 | Cytotoxic activity of gypenosides and gynogenin against non-small cell lung carcinoma A549 cells显示文摘 | Chen OJ Liu HM Xing SF | 2014 | Bioorg Med Chern Lett2014，24，1： | 1 |
| 14 | Co-detection in the pathogenesis of severe hand-foot-mouth disease 显示文摘 | Liu LJ Xu HM Li XJ | 2012 | Arch Virol2012，157，11： | 1 |
| 15 | Hyperperfusion syndrome with hemorrhage after angioplasty for middle cerebral artery stenosis显示文摘 | Do HM Albers GW | 2001 | AJNR Am J Neuroradiol2001，22，： | 1 |
| 16 | The Chinese diagnostic criteriafor osteoporosis suggested(second draft)显示文摘 | LIU ZH YANG D ZH ZHU HM | 2000 | Chinese Journal of Osteo-porosis2000，6，1： | 1 |
| 17 | BAFF-an essential survival factor for B cells:Links to genesis of ITP and may be of therapeutic target显示文摘 | Yu HM Liu YF Hou M | 2008 | Med Hypotheses2008，70，1： | 1 |
| 18 | Evaluation of inracranial and extracranial carotid steno-occlussive diseases in Taiwan Chinese patients with MR angiography显示文摘 | Liu HM Tu YK | 1996 | Stroke1996，27，： | 1 |
| 19 | Antidepressive effect of sodium val- proate involving suppression of corticotmpin-releasing factor expression and elevation of BDNF expression in rats exposed to chronic unprediet- ed stress显示文摘 | Qiu HM Yang JX Liu D | 2014 | Neuroreport2014，25，4： | 1 |
| 20 | Podoeyte lesions in patients with obesity related glomerulopathy显示文摘 | Chen HM Liu ZH Zeng CH | 2006 | Am J Kidney Dis2006，48，5： | 1 |
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