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| 1 | Structure and Mechanical Properties of Magnesium Alloy Treated by Plasma Electrolysis Oxidation Using Direct Current and High-frequency Bipolar Pulsing Modes显示文摘 | JIN Fanya Chu Paul K. XU Guidong ZHAO Jun SHEN Liru TONG Honghui | 2006 | Southwestern Institute of Physics Annual Report2006，，1： | 29 |
| 2 | Clinical characterization and diagnosis of cystic fibrosis throughexome sequencing in Chinese infants with Bartter-syndrome-like hypokalemia alkalosis显示文摘Cystic fibrosis (CF) is a fatal autosomal-recessive disease caused by mutations in the CFtransmembrane conductance regulator (CFTR) gene. CF is characterized by recurrent pulmonary infectionwith obstructive pulmonary disease. CF is common in the Caucasian population but is rare in the Chinesepopulation. The symptoms of early-stage CF are often untypical and may sometimes manifest as Bartter syndrome(BS)-like hypokalemic alkalosis. Therefore, the ability of doctors to differentiate CF from BS-like hypokalemicalkalosis in Chinese infants is a great challenge in the timely and accurate diagnosis of CF. In China, sporadic CFhas not been diagnosed in children younger than three years of age to date. Three infants, who were initiallyadmitted to our hospital over the period of June 2013 to September 2014 with BS-like hypokalemic alkalosis, werediagnosed with CF through exome sequencing and sweat chloride measurement. The compound heterozygousmutations of the CFTR gene were detected in two infants, and a homozygous missense mutation was found in oneinfant. Among the six identified mutations, two are novel point mutations (c.1526G 〉 C and c.3062C 〉 T) that arepossibly pathogenic. The three infants are the youngest Chinese patients to have been diagnosed with sporadic CFat a very early stage. Follow-up examination showed that all of the cases remained symptom-free after earlyintervention, indicating the potential benefit of very early diagnosis and timely intervention in children with CF.Our results demonstrate the necessity of distinguishing CF from BS in Chinese infants with hypokalemic alkalosisand the significant diagnostic value of powerful exome sequencing for rare genetic diseases. Furthermore, ourfindings expand the CFTR mutation spectrum associated with CF. | Liru Qiu Fengjie Yang Yonghua He Huiqing Yuan Jianhua Zhou | 2018 | Frontiers of Medicine2018，12，5： | 7 |
| 3 | Structure and Microwave Absorbing Properties of Fe Particle Containing Alumina Prepared by Micro-arc Oxidation显示文摘 | JIN Fanya TONG Honghui LI Jiong SHEN Liru Chu Paul K. | 2006 | Southwestern Institute of Physics Annual Report2006，，1： | 6 |
| 4 | Composition Optimization and Microstructure Design in MOFs-Derived Magnetic Carbon-Based Microwave Absorbers:A Review显示文摘Magnetic carbon-based composites are the most attractive candidates for electromagnetic(EM)absorption because they can terminate the propagation of surplus EM waves in space by interacting with both electric and magnetic branches.Metal-organic frameworks(MOFs)have demonstrated their great potential as sacrificing precursors of magnetic metals/carbon composites,because they provide a good platform to achieve high dispersion of magnetic nanoparticles in carbon matrix.Nevertheless,the chemical composition and microstructure of these composites are always highly dependent on their precursors and cannot promise an optimal EM state favorable for EM absorption,which more or less discount the superiority of MOFs-derived strategy.It is hence of great importance to develop some accompanied methods that can regulate EM properties of MOFs-derived magnetic carbon-based composites e ectively.This review comprehensively introduces recent advancements on EM absorption enhancement in MOFs-derived magnetic carbon-based composites and some available strategies therein.In addition,some challenges and prospects are also proposed to indicate the pending issues on performance breakthrough and mechanism exploration in the related field. | Honghong Zhao Fengyuan Wang Liru Cui Xianzhu Xu Xijiang Han Yunchen Du | 2021 | Nano-Micro Letters2021，13，12： | 6 |
| 5 | Experimental study of the wake characteristics of a two-blade horizontal axis wind turbine by time-resolved PIV显示文摘Wind tunnel experiments of the wake characteristics of a two-blade wind turbine, in the downstream region of 0 | ZHANG LiRu XING JiangKuan WANG JianWen YUAN RenYu DONG XueQing MA JianLong LUO Kun QIU KunZan NI MingJiang CEN KeFa | 2017 | Science China(Technological Sciences)2017，60，4： | 4 |
| 6 | The role of personality,social economic and prevention strategy effects on health-related quality of life among people living with HIV/AIDS显示文摘Background::HIV/AIDS has transformed into a chronic controllable but not yet curable infectious disease as other chronic diseases to some extent.The additional of so called fourth 90%that included the improved health-related quality of life(HRQoL)for people living with HIV(PLWHIV)required solutions beyond antiretroviral therapy and viral load suppression.This study will explore the role of personality,social economic and prevention strategy effection on HRQoL among people living with HIV/AIDS.Methods::A cross-sectional study was conducted among PLWHIV aged more than 16 years old in the 10 municipalities in Yunnan Province,China from October 2019 to May 2020,enrolling total 1997 participants.Individual-level HRQoL data were measured by 12-item Short Form Health Survey(SF-12)and EuroQol Five Dimensions Questionnaire(EQ-5D-5L).We assembled municipal-level data about social economic from Yunnan Statistical Yearbook in 2020 and strategy practice information from the self-evaluation system.We used the principal component analysis to build the social economic and strategy effect on each area respectively and one-way ANOVA was used to perform univariate analysis to identify the predictors with significant differences.Finally we used multi-level model(MLM)to explore the personality,social economic and strategy effects in health-related quality of life among PLWHIV.Results::The global score for quality of life measured using EQ-5D-5L had an estimated mean score(standard deviation,SD)of 0.901±0.146.The HRQoL score measured using PCS-12 had an estimated mean score(SD)of 46.62±8.55.The mean MCS-12 score(SD)was estimated to be 47.80±9.71.The area-level predictors explained a proportion of 13.6-17.2%for the between-area variation of the HRQoL scores,regardless of the total HRQoL,physical component and mental component.The impacts of stigma(P<0.01),social support(P<0.001),anxiety(P<0.001),depression(P<0.05)and social economic status(P<0.05)on HRQoL at the individual-level were significantly different.The plots visualized the impact of individual-level factors on a respondent’s HRQoL was modified by the area-level characteristics.Conclusions::The study identified the possible strategy determinant of individual HRQoL of PLWHIV and also the area effect on HRQoL.Stigma,social support,anxiety,depression and social economic status were the individual-level determinants on HRQoL.These could be a valuable resource for evaluating the overall health of the areas and help improve local decision making. | Xiaowen Wang Hongbing Luo Enlong Yao RenhaiTang Wenbin Dong Fuyong Liu Jun Liang Huilan Li Minyang Xiao Zuyang Zhang Jin Niu Lijun Song Liru Fu Xuehua Li Shicong Qian Qing Guo Zhizhong Song | 2021 | Infectious Diseases of Poverty2021，10，4： | 3 |
| 7 | Micro-structural and Dielectric Properties of Porous TiO2 Films Synthesized on Titanium Alloys by Micro-arc Discharge Oxidization显示文摘 | JIN Fanya TONG Honghui SHEN Liru WANG Ke Chu Paul K. | 2006 | Southwestern Institute of Physics Annual Report2006，，1： | 3 |
| 8 | Characterization of micro-arc ceramic coatings on Ti-2Al-2.5Zr alloy substrates显示文摘Titanium oxide coatings were synthesized on Ti-2Al-2.5Zr alloy substrates by micro-arc oxidation (MAO) tech-nique. The surface features of the coatings were studied by scanning electron microscopy. The micro-arc discharge channels of the Ti-2Al-2.5Zr alloy decrease while the discharge channel size increases clearly with an increase in treating time. With an increase of the coating thickness the porous layer thickness increases apparently. Phase composition of the surface layers of the coatings was evaluated by X-ray diffraction and X-ray photoelectron spectroscopy. The results of XRD and XPS analysis show that the MAO coating mainly consists of anatase and rutile TiO2. | HE Xiao WU Jihong SHEN Liru | 2007 | Rare Metals2007，26，5： | 2 |
| 9 | QTL mapping of agronomic and economic traits for four F_(2)populations of upland cotton显示文摘Background:Upland cotton(Gossypium hirsutum)accounts for more than 90%of the annual world cotton output because of its high yield potential.However,yield and fiber quality traits often show negative correlations.We constructed four F_(2)populations of upland cotton,using two normal lines(4133B and SGK9708)with high yield potential but moderate fiber quality and two introgression lines(Suyuan04–3 and J02–247)with superior fiber quality,and used them to investigate the genetic basis underlying complex traits such as yield and fiber quality in upland cotton.We also phenotyped eight agronomic and economic traits and mapped quantitative trait loci(QTLs).Results:Extensive phenotype variations and transgressive segregation were found across the segregation populations.We constructed four genetic maps of 585.97 centiMorgan(cM),752.45 cM,752.45 cM,and 1163.66 cM,one for each of the four F_(2)populations.Fifty QTLs were identified across the four populations(7 for plant height,27 for fiber quality and 16 for yield).The same QTLs were identified in different populations,including qBW4 and qBW2,which were linked to a common simple sequence repeat(SSR)marker,NAU1255.A QTL cluster containing eight QTLs for six different traits was characterized on linkage group 9 of the 4133B×Suyuan04–3 population.Conclusions:These findings will provide insights into the genetic basis of simultaneous improvement of yield and fiber quality in upland cotton breeding. | LI Hongge PAN Zhaoe HE Shoupu JIA Yinhua GENG Xiaoli CHEN Baojun WANG Liru PANG Baoyin DU Xiongming | 2021 | Journal of Cotton Research2021，4，1： | 2 |
| 10 | Overexpression of amplified in breast cancer 1 (AIB1) gene promotes lung adenocarcinoma aggressiveness in vitro and in vivo by upregulating C-X-C motif chemokine receptor 4显示文摘Background:We previously found that overexpression of the gene known as amplified in breast cancer 1(AIB1)was associated with lymph node metastasis and poor prognosis in patients with lung adenocarcinoma.However,the role of AIB1 in that malignancy remains unknown.The present study aimed to investigate the function of AIB1 in the process of lung adenocarcinoma cell metastasis.Methods:A series of in vivo and in vitro assays were performed to elucidate the function of AIB1,while real-time PCR and Western blotting were utilized to identify the potential downstream targets of AIB1 in the process of lung adenocarcinoma metastasis.Rescue experiments and in vitro assays were performed to investigate whether the invasive-ness of AIB1-induced lung adenocarcinoma was mediated by C-X-C motif chemokine receptor 4(CXCR4).Results:The ectopic overexpression of AIB1 in lung adenocarcinoma cells substantially enhanced cell migration and invasive abilities in vitro and tumor metastasis in vivo,whereas the depletion of AIB1 expression substantially inhibited lung adenocarcinoma cell migration and invasion.CXCR4 was identified as a potential downstream target of AIB1 in lung adenocarcinoma.The knockdown of AIB1 greatly reduced CXCR4 gene expression at both the transcription and protein levels,whereas the knockdown of CXCR4 in cells with AIB1 ectopic overexpression diminished AIB1-induced migration and invasion in vitro and tumor metastasis in vivo.Furthermore,we found a significant positive association between the expression of AIB1 and CXCR4 in lung adenocarcinoma patients(183 cases),and the co-overexpression of AIB1 and CXCR4 predicted the poorest prognosis.Conclusions:These findings suggest that AIB1 promotes the aggressiveness of lung adenocarcinoma in vitro and in vivo by upregulating CXCR4 and that it might be usable as a novel prognostic marker and/or therapeutic target for this disease. | Liru He Haixia Deng Shiliang Liu Jiewei Chen Binkui Li Chenyuan Wang Xin Wang Yiguo Jiang Ningfang Ma Mengzhong Liu Dan Xie | 2018 | Cancer Communications2018，38，1： | 2 |
| 11 | Analysis of the overall energy intensity of alumina refinery process using unit process energy intensity and product ratio method显示文摘 | LIU Liru LU Aye LU Zhongwu | | 0，，8： | 1 |
| 12 | Study on Ceramsite 显示文摘 | Ding Peixi Yin Liru | 2012 | Advaneed Materials Research2012，，374377： | 1 |
| 13 | The developing strategy of environmental logistics显示文摘 | Zhang Liru | | 0，，： | 1 |
| 14 | Enhanced stability of Pt/Al_(2)O_(3) modified by Zn promoter for catalytic dehydrogenation of ethane显示文摘Catalytic ethane dehydrogenation(EDH) to ethylene over Pt-based catalysts has received increasing interests in recent years as it is a potential alternative route to conventional steam cracking. However, the catalysts used in this reaction often suffer from rapid deactivation due to serious coke deposition and metal sintering. Herein, we reported the effects of Zn modification on the stability of Pt/Al2 O3 for EDH.The Zn-modified sample(PtZn2/Al2 O3) exhibits stable ethane conversion(20%) with over 95% ethylene selectivity. More importantly, it exhibits a significantly low deactivation rate of only 0.003 h-1 at 600 °C for70 h, which surpasses most of previously reported catalysts. Detailed characterizations including in situ FT-IR, ethylene adsorption microcalorimetry, and HAADF-STEM etc. reveal that Zn modifier reduces the number of Lewis acid sites on the catalyst surface. Moreover, it could modify Pt sites and preferentially cover the step sites, which decrease surface energy and retard the sintering of Pt particle, then prohibiting the further dehydrogenation of ethylene to ethylidyne. Consequently, the good stability is realized due to anti-sintering and the decrease of coke formation on the Pt Zn2/Al2 O3 catalyst. | Xiaoyu Li Yanliang Zhou Botao Qiao Xiaoli Pan Chaojie Wang Liru Cao Lin Li Jian Lin Xiaodong Wang | 2020 | Journal of Energy Chemistry2020，29，12： | 1 |
| 15 | Polymer-bubbling for one-step synthesis of three-dimensional cobalt/carbon foams against electromagnetic pollution显示文摘Constructing three-dimensional(3D)foam-like structure in magnetic metal/carbon composites is regarded as a promising pathway to reinforce their electromagnetic(EM)functions.Herein,a nitrateassisted polymer-bubbling strategy is reported for the synthesis of Co/carbon foams,which is simply accomplished by direct pyrolyzing the mixture of polyvinylpyrrolidone(PVP)and cobalt nitrate hexahydrate(Co(NO_(3))_(2)·6 H_(2) O).Co(NO_(3))_(2)·6H_(2)O not only plays as the source of Co nanoparticles,but also accounts for the formation of 3D microstructure through releasing gas.By manipulating the weight ratio of Co(NO_(3))_(2)·6H_(2)O to PVP,the chemical composition,microstructure,and EM properties of these composites can be easily regulated.When the weight ratio reaches 1.5,the resultant composite displays good microwave absorption performance,whose reflection loss intensity and effective absorption bandwidth are superior to those of many common Co/C composites.EM analysis reveals that such architecture is greatly helpful to establish cross-linked conductive networks in the wax matrix,resulting in powerful dielectric loss under low absorber loading.Meanwhile,3D microstructure is also beneficial for multiple reflections that equal to extend the transmission path of incident EM waves.Simple synthesis strategy and desirable properties of these magnetic carbon foams may render them as the low-cost substitute of 3D graphene for the application against EM pollution. | Fengyuan Wang Ping Xu Ning Shi Liru Cui Yahui Wang Dawei Liu Honghong Zhao Xijiang Han Yunchen Du | 2021 | Journal of Materials Science & Technology2021，，34： | 1 |
| 16 | Analysis of the overall energy intensity of alumina refinery process using unit process energy intensity and product ratio method显示文摘 | Liru Liu Lu Aye Zhongwu Lu Peihong Zhang | 2005 | Energy2005，，8： | 1 |
| 17 | Effect of material flows on energy intensity in process industries显示文摘 | Liru Liu Lu Aye Zhongwu Lu Peihong Zhang | 2005 | Energy2005，，12： | 1 |
| 18 | Human bone marrow stem cells exhibit neural phenotypes and ameliorate neurological deficits after graftiong int the ischemix brain of rats显示文摘 | ZHAO Liru DUAN Weiming REYES M | 2002 | Exp Neurol2002，174，： | 1 |
| 19 | Red blood cell membrane-camouflaged nanoparticles loaded with AIEgen and Poly(I: C) for enhanced tumoral photodynamic-immunotherapy显示文摘Red blood cell(RBC)-mimicking nanoparticles(NPs) offer a promising platform for drug delivery because of their prolonged circulation time, reduced immunogenicity and specific targeting ability. Herein, we report the design and preparation of RBC membrane-bound NPs(M@AP), for tumoral photodynamic-immunotherapy. The M@AP is formed by self-assembly of the positively charged aggregation-induced emission luminogen(AIEgen)(named P2-PPh3) and the negatively charged polyinosinic : polycytidylic acid(Poly(I : C)), followed by RBC membrane encapsulation. P2-PPh3 is an AIE-active conjugated polyelectrolyte with additional photosensitizing ability for photodynamic therapy(PDT), while Poly(I : C) serves as an immune-stimulant to stimulate both tumor and immune cells to activate immunity, and thus reduces tumor cell viability. When applied in tumor-bearing mice, the M@AP NPs are enriched in both the tumor region as a result of an enhanced permeability and retention(EPR)effect, and the spleen because of the homing effect of the RBC-mimicking shell. Upon light irradiation,P2-PPh3 promotes strong ROS generation in tumor cells, inducing the release of tumor antigens(TA). The anti-tumor immunity is further enhanced by the presence of Poly(I : C) in M@AP. Thus, this strategy combines the PDT properties of the AIE-active polyelectrolyte and immunotherapy properties of Poly(I : C) to achieve synergistic activation of the immune system for anti-tumor activity, providing a novel strategy for tumor treatment. | Jun Dai Meng Wu Quan Wang Siyang Ding Xiaoqi Dong Liru Xue Qingqing Zhu Jian Zhou Fan Xia Shixuan Wang Yuning Hong | 2021 | National Science Review2021，8，6： | 1 |
| 20 | Control of growth,secondary metabolism and sporulation in streptomyces venezuelae ISP5230 by jadW1,a member of the afsA family of c-butyrolactone regulatory genes显示文摘 | Liru W Leo C V | 2003 | Microbiology2003，，149： | 1 |
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