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| 1 | Alzheimer型痴呆的髓鞘素蛋白自身应答性T细胞免疫反应显示文摘通过计数分泌细胞因子γ-干扰素(IFN-γ)、辅助性T细胞(Th1),检查AD患者外周血和脑脊液(CSF)中T细胞免疫应答。方法:将单个核细胞(MNC)暴露于中枢神经系统(CNS)髓鞘素抗原髓鞘碱性蛋白(MBP)和含脂质蛋白(PLP)中进行体外短时间培养,用酶联免疫斑点试验(Elispot)检测IFN-γ分泌性Th1细胞链,同时检测急性脑血管病(CVD)和其他神经疾病(OND)患者作为对照。结果显示AD患者外周血中呈高水平MBP应答性Th1细胞链,而其CSF中尤为明显,外周血中PLP应答性Th1细胞亦显著高于OND对照组。结论认为AD患者存在高水平的髓鞘素蛋白自身应答性T细胞反应,且在与CNS紧邻的CSF中表现得尤为显著,其在AD发病机制中的作用还有待进一步深入探讨。 | 王维治 肖保国 Link H | 1996 | 中华神经科杂志1996，29，3： | 4 |
| 2 | Evolution of EV71 genogroup in Taiwan from 1998 to 2005 : An emerging of subgenogroup CA of EV71 显示文摘 | LINK H HWANG K P KEG M | 2006 | J Med Virol2006，78，2： | 1 |
| 3 | Principles of albumin and IgG analysis in neurological disorders of reference values 显示文摘 | Tibbling G Link H | 1977 | Scand J Lab Invest1977，37，5： | 1 |
| 4 | Increased IL-1 beta, IL-8 and IL-17 mRNA expression in blood mononuclear cells observed in a prospective ischemic stroke study显示文摘 | Kostulas N Pelidon SH Kivisakk P Kostulas V Link H | 1999 | Stroke1999，30，10： | 1 |
| 5 | A study on the machining characteristics of TiNi shape memory alloys 显示文摘 | LIN H C LINK M CHEN Y C | 2000 | Journal of Materials Processing Technology2000，105，： | 1 |
| 6 | Antigen-specific T cell functions are suppressed over the estrogendendritie eell-indoleamine 2,3-dioxygenase axis显示文摘 | Xiao BG Liu X Link H | 2004 | Steroids2004，69，： | 1 |
| 7 | Sn-Zn-Al Pb-free solder- an inherent barrier solder for Cu contact 显示文摘 | LINK L HSU H M | 2001 | J Electron Mater2001，30，9： | 1 |
| 8 | Vascular endothelial growth factor (VEGF) induces remodeling and enhances Th2-nlediated sensitization and inflammation in the lung 显示文摘 | Lee CG Link H Baluk P at al | 2004 | Nat Med2004，10，10： | 1 |
| 9 | Antigen-specific T cell functions are suppressed over the estrogen-dendritic eell-indoleamine 2, 3- dioxygenase axis 显示文摘 | Xiao B G Liu X Link H | 2004 | Steroids2004，69，10： | 1 |
| 10 | Action of chelators in iron-overloaded cardiac ceils: accessibility to intracellular labile iron and functional consequences 显示文摘 | Glickstein H EI RB Link G | 2006 | Blood2006，108，： | 1 |
| 11 | Transplantation of allogenic CD34+ blood cells显示文摘 | Arseniev L Bhre O | 1996 | Blood1996，87，： | 1 |
| 12 | Rapid non-separation electrochemiluminesc- scence DNA hybridization assays for PCR Product,using 3 labelled oligonucleotide probes显示文摘 | GUDIBANDE S KENTEN J H LINK J | 1992 | Mel Cell Probes1992，6，6： | 1 |
| 13 | Treatment of interstitial pneumonitis due to cytomegalovirus with ganciclovir and intravenous immunoglobulin : experience of European Bone Marrow Transplant Group 显示文摘 | Ljungman P Engelhard D Link H | 1992 | Clin Infect Dis1992，14，4： | 1 |
| 14 | Oligoclonal immunoglobulin in cerebrovascular diseases显示文摘 | Rostrom B Link H | 1981 | Neurology1981，31，： | 1 |
| 15 | Oligoclonal IgG bands in cerebrospinal fluid:Principles for demonstration and interpretation based on findings in 1114 neurological patients 显示文摘 | Kostulas VK Link H Lefvert AK | 1987 | Arch Neurol1987，44，： | 1 |
| 16 | The use of hyperbaric oxygenation in the treatment of spinal cord lesions 显示文摘 | Holbach KH Wassmann H Linke D | 1977 | Eur Neurol1977，16，16： | 1 |
| 17 | Vascular endothelial growth factor(VEGF) induces remodeling and enhances TH2-mediated sensitization and infammation in the lung显示文摘 | Lee CG Link H Boluk P | 2004 | Nat Med2004，10，10： | 1 |
| 18 | Rat model as tool to develop new immunotherapies显示文摘 | Link H Xiao BG | 2001 | Immunol Rev2001，184，： | 1 |
| 19 | Effect of glatiramer acetate(Copaxone)on CD4+CD25 high T regulatory cells and their IL-10 production in multiple sclerosis显示文摘 | PUTHETI P SODERSTROM M LINK H | 2003 | J Neuroimmunol2003，144，12： | 1 |
| 20 | Surgery of colorectal cancer: surgical morbidity and five - and ten - year results in 2400 patients - monoinstitutional experience 显示文摘 | STAIB L LINK K H BLATZ A et ai | 2002 | World jour- nal of surgery2002，26，1： | 1 |
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