|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | On strongest necessary and weakest sufficient conditions 显示文摘 | LIN FANGZHEN | 2001 | Artificial Intelligence2001，128，1： | 1 |
| 2 | On Strongest Necessary and Weakest Sufficient Conditions显示文摘 | Lin Fangzhen | 2001 | Artificial Intelligence2001，128，12： | 1 |
| 3 | ASSAT:computing answer sets of a logic program by sat solved显示文摘 | Fangzhen Lin Yuting Zhao | 2004 | Artificial Intelligence2004，157，12： | 1 |
| 4 | ASSAT: computing answer sets of a logic program by SAT solvers 显示文摘 | Fangzhen Lin and Yuting Zhao | 2004 | Artificial Intelligence2004，157，12： | 1 |
| 5 | Effect of Roucongrong(Herba Cistanches Deserticolae) decoction on the substantia nigra through Wnt/β-catenin signaling pathway in rats with Parkinson's disease induced by 6-hydroxydopamine hydrochloride显示文摘OBJECTIVE:To investigate the effect of Roucongrong(Herba Cistanches Deserticolae)decoction on the substantia nigra in rats with Parkinson’s disease(PD)induced by 6-hydroxydopamine hydrochloride(6-OHDA).To further determine whether the Wnt/β-catenin signaling pathway is involved in the action.METHODS:A rat model of PD was established by intracranial injection of 6-OHDA.Subsequently,three concentrations of Roucongrong(Herba Cistanches Deserticolae)decoction were prepared and administered to rats by gavage therapy for 14 d.Behavioral changes were measured in PD rats.In vivo tyrosine hydroxylase(TH)levels in the substantia nigra were examined by immunohistochemistry.Additionally,gene and protein expression levels of members of the Wnt/β-catenin signaling pathway were examined by Western blotting and polymerase chain reaction.Lastly,a Wnt/β-catenin inhibitor was used to investigate the mechanism of action in 1-methyl-4-phenylpyridinium(MPP+)-treated MES23.5 cells in vitro.RESULTS:Roucongrong(Herba Cistanches Deserticolae)decoction improved performance in the stride and gait adjustment tests in PD rats.It also increased TH in the substantia nigra and altered the expression of genes and proteins in the Wnt/β-catenin signaling pathway.Wnt/β-catenin inhibitor reduced the effect of Roucongrong(Herba Cistanches Deserticolae)decoction in MPP+-treated MES23.5 cells.CONCLUSION:Roucongrong(Herba Cistanches Deserticolae)decoction may promote neuronal survival in PD in vivo and in vitro by increasing TH content in the substantia nigra and by activating the Wnt/β-catenin signaling pathway. | XU Qian QIN Wei WU Fangzhen LIN Yao HONG Liting CHEN Dan HU Xuefeng CAI Jing | 2021 | Journal of Traditional Chinese Medicine2021，41，5： | 1 |
| 6 | A characterization of answer sets for logic programs显示文摘Checking if a program has an answer set, and if so, compute its answer sets are just some of the important problems in answer set logic programming. Solving these problems using Gelfond and Lifschitz's original definition of answer sets is not an easy task. Alternative characterizations of answer sets for nested logic pro- grams by Erdem and Lifschitz, Lee and Lifschitz, and You et al. are based on the completion semantics and various notions of tightness. However, the notion of tightness is a local notion in the sense that for different answer sets there are, in general, different level mappings capturing their tightness. This makes it hard to be used in the design of algorithms for computing answer sets. This paper proposes a characterization of answer sets based on sets of generating rules. From this char- acterization new algorithms are derived for computing answer sets and for per- forming some other reasoning tasks. As an application of the characterization a sufficient and necessary condition for the equivalence between answer set seman- tics and completion semantics has been proven, and a basic theorem is shown on computing answer sets for nested logic programs based on an extended notion of loop formulas. These results on tightness and loop formulas are more general than that in You and Lin's work. | ZHANG MingYi ZHANG Ying FangZhen LiN | 2007 | Science in China(Series F)2007，50，1： | 1 |
| 7 | On strongest necessary and weakest su_cient condi- tions 显示文摘 | Fangzhen Lin | 2001 | Artificial Intelligence2001，128，12： | 1 |
| 8 | On strongest necessary and weakest sufficient conditions 显示文摘 | Lin Fangzhen | 2001 | Artificial Intelligence2001，128，12： | 1 |
| 9 | Bcl-2shRNA转染联合塞莱昔布对胃癌细胞株SGC-7901的影响(英文)显示文摘Objective:The aim of this study was to study the changes of SGC-7901 cells transfecting small hairpin RNA(shRNA) targeted Bcl-2 and celecoxib in vitro.Methods:To use the effective siRNA targeted to Bcl-2 by Lipofectamine 2000,the rate of cell growth inhibition of all groups was detected by multiply-table tournament(MTT) method,apoptosis rate was examined by flow cytometry and the expression of Bcl-2 was assayed by Elisa.Results:After siRNA was transfected to SGC-7901 cells,the rate of cell growth inhibition was increased,the joint group was higher by flow cytometry and the expression of Bcl-2 was lower by Elisa.Conclusion:The growth of SGC-7901 cells which was transfected siRNA has been inhibited,and the sensitivity to celecoxib has been increased. | Weiwei Liu Aiqin Wang Wenjing Xiao Fangzhen Shen Minggang Lin Ruyong Yao | 2012 | The Chinese-German Journal of Clinical Oncology2012，11，2： | 0 |
您所在的机构暂未开通此部分的功能，请联系管理员