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| 1 | 中国成人糖尿病、血糖与结直肠癌发病率:针对50万人的前瞻性研究显示文摘背景糖尿病可致结直肠癌(CRC)的发病风险升高。糖尿病病程和非糖尿病患者的血糖与CRC发病风险之间的相关性仍不清楚。方法2004至2008年前瞻性中国Kadoofe Biobank研究从10个不同地区纳入了512 713名受试者。在10年随访期间,在基线无癌症史的510 136名受试者中共记录有3 024例新发CRC病例(1 745例结肠癌,1 716例直肠癌)。应用Cox回归分析对糖尿病(入组前诊断或筛查发现的)或无糖尿病病史者随机血糖(RPG)水平与CRC发病相关性的校正风险比(HR)进行估计。结果基线时,共有5.8%的受试者患有糖尿病。糖尿病患者发生CRC的校正HR为1.18(95%可信区间1.04~1.33),且发生结肠癌与直肠癌的风险相当[1.19(1.01~1.39)比1.14(0.96~1135)]。这些患者发生CRC的HR随糖尿病病程的延长而下降(趋势P值为0.03)。在入组前无糖尿病的受试者中,其RPG水平与CRC发病呈正相关,基线RPG每升高1 mmol/L其发生CRC的校正HR为1.04(1.02~1.05),且发生结肠癌与直肠癌的风险亦相当[1.03(1.01~1.05)比1.04(1.02~1.06)]。在男性中,糖尿病和RPG与CRC发病风险的相关性高于女性,但其差异无统计学意义(异质性检验的P值分别为0.3和0.2)。讨论在中国成年人中,未诊断糖尿病者其糖尿病和升高的血糖水平与CRC发病风险升高相关。 | Yuanjie Pang Christiana Kartsonak yu Guo Yiping Chen Ling Yang Zheng Bian Fiona Bragg Iona Y Millwood Leijia Shen Songgen Zhou Jiben Liu Junshi Chen Liming Li Michael V Holmes Zhengming Ghen 霍永丰(译) | 2019 | 英国医学杂志中文版2019，22，1： | 6 |
| 2 | On strategies for imbalanced text classification using SVM: a comparative study显示文摘 | SUN A X LIME E LIU Y | 2009 | Decision Support Systems2009，48，1： | 1 |
| 3 | MDM2, P53P21WAF1 and pAKT protein levels in genesis and behaviour of adenoid cystic carcinoma 显示文摘 | De lime Mde D Marques Y M Alves sde M Jr | 2009 | Cancer Epidemiology2009，33，2： | 1 |
| 4 | On strategies for imbalanced text classification using SVM: a comparative study 显示文摘 | SUN A LIME P LIU Y | 2009 | Decision Support Systems2009，48，1： | 1 |
| 5 | Muhicomponent induction response in a borehole environment显示文摘 | Tsili W Liming Y Fanini O | 2003 | Geophysics2003，68，4： | 1 |
| 6 | Chan- ges in vegetation net primary productivity from 1982 to 1999 in China 显示文摘 | Piao Shirong Fang Jingyun Y Zhou Liming | 2005 | Global Biogeochemical Cycles2005，19，2： | 1 |
| 7 | Myriad design and implementation of a federated database prototype显示文摘 | LIME P HWANG S Y JAIDEEP S | 1995 | Software-Practice & Exper1995，25，5： | 1 |
| 8 | Natural mechanism of the broadened ShOCk relaxation profile in ternary body-centeredcubic alloys 显示文摘 | Liming Y Puxing Y Dehai P | 2007 | Physical Review B Condensed Matter and Materials Physics2007，75，17： | 1 |
| 9 | Effect soils显示文摘 | KAMON M YING C Y KATSUMI on lime and cement stabilized Foundations 1996 36(4): 91 - 99 T | 1996 | of acid rain Soils and1996，，： | 1 |
| 10 | Image shadow removal using pulse coupled neural network 显示文摘 | Xiaodong G Daoheng Y Liming Z | 2005 | IEEE Trans Neural Networks2005，16，3： | 1 |
| 11 | Translation and validation of a Chinese version of the 8-item Morisky medication adherence scale in myocardial infarction patients 显示文摘 | Jun Y Liming Y Qiaohong Y | 2014 | J Eval Clin Pract2014，20，4： | 1 |
| 12 | Efficient algorithms for mining maximal valid groups 显示文摘 | WANG Y LIME P HWANG S Y | 2008 | The international journal on very large data bases2008，17，3： | 1 |
| 13 | Bidirectional field-flow particle separation methodin a dielectrophoretic chip with3D electrodes显示文摘 | CIPRIAN I LIMING Y FRANCIS E H T | 2008 | Sensors and Actuators:B2008，129，1： | 1 |
| 14 | Analysis of interannual changes in northern vegetation activity observed in AVHRR data from 1981 to 1994显示文摘 | Shabanov N V Zhou Liming Knyazikhin Y | 2002 | IEEE Transactions on Geoscience and Remote Sensing2002，40，1： | 1 |
| 15 | Differential proteomic analysis of proteins in wheat spikes induced by Fusarium graminearum显示文摘 | Yun W Liming Y Haibin X Qifu L Zhengqiang M Chenggen C | 2005 | Proteomics2005，5，： | 1 |
| 16 | Image thinning using pulse coupled neural network 显示文摘 | XIAODONG G DAOHENG Y LIMING Z | 2004 | Pattern Recognition Letters2004，25，： | 1 |
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