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| 1 | Identification of the Mamestra configurata (Lepidoptera Noctuidae) peritrophic matrix proteins and enzymes involved in peritrophic matrix chitin metabolism显示文摘peritrophic 矩阵(下午) 为昆虫是必要的它由食物粒子,病原体,和毒素保护 midgut 上皮免受损坏的伤害的消化系统生理学。下午也由于它的 per os 可接近性是为新害虫控制策略的开发的一个吸引人的目标。理解 PM 怎么执行这些函数, PM 的分子的体系结构用 genomic 被检验, proteomic 在 Mamestra configurata 来临(鳞翅目:Noctuidae ) ,饰有十字架的 oilseed 的一个主要害虫在北美洲收割。PM 的液体层析双人脚踏车团 spectrometry 分析识别了是分类的 82 蛋白质:(i) peritrophins,与一个 CBDIII 领域包括一个新班;(ii ) 酶在几丁质修正(几丁质 deacetylases ) 包含了,消化(丝氨酸朊酶, aminopeptidases, carboxypeptidases,脂肪分解酵素和 α-amylase ) 或另外的反应(β-1,3-glucanase,碱的磷酸酶, dsRNase,虾红素, pantetheinase ) ;(iii ) 没有已知的 orthologs,由 polycalin, REPAT, serpin, C 类型 lectin 和 Lsti99/Lsti201 和 3 新奇蛋白质组成的一个异质的组。编码下午蛋白质的基因在 midgut 主要被表示。cDNAs 编码几丁质 synthase-2 (McCHS-2 ) , chitinase (McCHI ) ,和 β-N-acetylglucosaminidase (McNAG ) 酶,在下午几丁质新陈代谢包含了,也被识别。McCHS-2 表示对显示它为在 PM,的几丁质合成负责的 midgut 特定在 midgut 的唯一的几丁质的材料。相反,编码 chitinolytic 酶的基因在多重纸巾被表示。McCHS-2, McCHI,和 McNAG 在喂幼虫的 midgut 被表示,并且唠叨活动在 PM 是在场的。这个信息被用来产生鳞翅类的下午建筑学的一个更新的模型。 | Umut Toprak Martin Erlandson Doug Baldwin Steve Karcz Lianglu Wan Cathy Coutu Cedric Gillott Dwayne D. Hegedus | 2016 | Insect Science2016，23，5： | 4 |
| 2 | A Methodology of Epidemiologic Study in the General Population Focusing on Food Allergy—China, 2020显示文摘Introduction:Adverse reactions to food(ARF)are a major worldwide public health and food safety problem.Among the various causes of ARF,food allergies(FA)are particularly serious as the immune response that is triggered can be fatal even at very low doses.However,the prevalence of ARF and FA in the general population in China is presently unclear.This study aims to determine the epidemiological characteristics and risk factors for ARF and FA,which can be a basis for estimating thresholds for major food allergens.Methods:This is a multicenter,cross-sectional,epidemiologic survey with a case-control study nested among a selected population in China.Random individuals were recruited using stratified cluster random sampling;ARF and FA were comprehensively assessed using modified EuroPrevall FA Project questionnaires as well as structured interviews,sensitization testing,and double-blind placebocontrolled food challenges(DBPCFC).Results:This method of epidemiologic study on ARF and FA was a pilot application in Jiangxi Province from January 2020;among the total 21,273 children and adults that completed the questionnaire,5.8%reported ARF and 4.3%reported FA.ARF were determined to be associated with age,gender,and region.Animal-derived foods were the dominant offending foods,especially shrimp,and skin symptoms were the most commonly reported ARF.Discussion:This is the first multi-center,largescale,epidemiologic study on ARF and FA using standardized methods,including DBPCFC,in the Chinese general population.This study presents an important approach to assessing ARF and FA,provides significant insights about the prevalence of ARF and FA,and facilitates support for updating the list of allergenic food labels:which will be essential for improving ARF prevention and management in China. | Hua Feng Yan Chen Hongbing Chen Chengwei Liu Wei Zhou Lianglu Wang Yongning Wu | 2022 | China CDC weekly2022，4，34： | 2 |
| 3 | Effect of calcium malonate on the formation of β crystalline form in isotactic poly(propylene)显示文摘 | QiangDou Qu‐LiangLu | 2008 | Polym. Adv. Technol2008，，11： | 1 |
| 4 | Effect of a calcium channel blocker and antispasmodic in diarrhoea‐predominant irritable bowel syndrome显示文摘 | Ching‐LiangLu Chih‐YenChen Full‐YoungChang Shen‐ShongChang Lih‐JiunKang Rei‐HwaLu Shou‐DongLee | 2001 | Journal of Gastroenterology and Hepatology2001，，8： | 1 |
| 5 | Characteristics of cow’s milk allergy and sensitization in Chinese patients显示文摘Globally,the prevalence of food allergy in children is estimated to be approximately 4%to 10%.[1]Food allergy usually begins early in the allergic march,and cow's milk allergy(CMA)is one of the most common food allergens in infants and children.In Europe,the overall incidence of challenge-proven CMA is 0.54%,and in the United States,the overall prevalence is 0.4%and pediatric prevalence is 1.9%.[2–4]In China,the prevalence of oral food challenge(OFC)-confirmed CMA is 0.83%to 3.5%in various cities.[5]Double-blind placebo-controlled food challenge is not applied widely in clinical practice because of its complex process and the risk of anaphylaxis for patients that receive the test.Allergen-specific IgE(sIgE)is usually used as a critical assessment method for food allergy. | Sainan Bian Ruiqi Wang Tao Xu Kai Guan Liping Wen Lianglu Wang- Jjanqing Gu Jinlyu Sun Rui Tang Yuxiang Zhi Hong Li Jia Yin | 2022 | Chinese Medical Journal2022，135，22： | 1 |
| 6 | Zingiber officinale (ginger) compounds have tetracycline‐resistance modifying effects against clinical extensively drug‐resistant Acinetobacter baumannii显示文摘 | Hui‐MinWang Chung‐YiChen Hsi‐AnChen Wan‐ChunHuang Wei‐RuLin Tun‐ChiehChen Chun‐YuLin Hsin‐JuChien Po‐LiangLu Chiu‐MeiLin Yen‐HsuChen | 2010 | Phytother Res2010，，12： | 1 |
| 7 | Effect of a calcium channel blocker and antispasmodic in diarrhoea‐predominant irritable bowel syndrome显示文摘 | Ching‐LiangLu Chih‐YenChen Full‐YoungChang Shen‐ShongChang Lih‐JiunKang Rei‐HwaLu Shou‐DongLee | 2001 | Journal of Gastroenterology and Hepatology2001，，8： | 1 |
| 8 | EEG-based vigilance estimation using extreme learning machines显示文摘 | SHI Lichen BAO Lianglu | 2013 | Neurocomputing2013，102，： | 1 |
| 9 | Silicone rubber/graphite nanosheet electrically conducting nanocomposite with a low percolation threshold显示文摘 | LingChen LiangLu DajunWu GuohuaChen | 2007 | Polym Compos2007，，4： | 1 |
| 10 | One-step Synthesis of Dipyrromethanes in the Presence of Ionic Liquid [Hmim]BF_4显示文摘Dipyrromethanes were obtained in moderate yields by the condensation of ketone and pyrrole in the presence of ionic liquid [Hmim]BF4 without using any strong acid and other organic solvent. | GuoHuaGAO LiangLU JinBaoGAO WenJuanZHOU JianGuoYANG XinYuYU MingYuanHE | 2005 | Chinese Chemical Letters2005，16，7： | 0 |
| 11 | Diagnostic accuracy and safety of Dermatophagoides pteronyssinus extracts used for skin prick test显示文摘Background:Dermatophagoides pteronyssinus is a common allergen causing allergic diseases in China.The aim of this study was to evaluate the efficacy and safety of D.pteronyssinus extracts produced by Peking Union Medical College Hospital(PUMCH)for the skin prick test(SPT)in the diagnosis of D.pteronyssinus allergy.Methods:A total of 910 subjects with allergic diseases were prescribed D.pteronyssinus SPT and specific sIgE(sIgE)test among the Outpatients of Department of Allergy,PUMCH from August 10,2015 to August 30,2017.Receiver operating characteristic curve(ROC)analysis was performed according to the results of D.pteronyssinus-sIgE detection.The accuracy of D.pteronyssinus extracts used for SPT in the diagnosis of D.pteronyssinus allergy was evaluated under different cutoff values.Adverse events after SPT were recorded to evaluate safety.Results:There were 796 and 618 subjects in the full analysis set(FAS)and the per protocol set(PPS),respectively.The areas under the curve of FAS and PPS were 0.871 and 0.873,respectively.According to the ROC of PPS,the optimal and 95%specificity diagnostic cutoff values of D.pteronyssinus SPT mean wheal diameter were 3.25 and 3.75 mm,respectively.No adverse events occurred.Conclusion:The extracts of D.pteronyssinus for SPT were simple,highly accurate,and safe and should be considered for recommendation in the clinical diagnosis of D.pteronyssinus allergy. | Rui Tang Xiaohong Lyu Yuxi Liu Ruiqi Wang Lianglu Wang Hong Li Jinlyu Sun Yuxiang Zhi Jianqing Gu Kai Guan Liping Wen Zixi Wang Lisha Li Le Cui Yingyang Xu Junxiong Zhou Tao Xu Jia Yin | 2022 | Chinese Medical Journal2022，135，21： | 0 |
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