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| 1 | Petawatt and exawatt class lasers worldwide显示文摘In the 2015 review paper‘Petawatt Class Lasers Worldwide’a comprehensive overview of the current status of highpower facilities of>200 TW was presented.This was largely based on facility specifications,with some description of their uses,for instance in fundamental ultra-high-intensity interactions,secondary source generation,and inertial confinement fusion(ICF).With the 2018 Nobel Prize in Physics being awarded to Professors Donna Strickland and Gerard Mourou for the development of the technique of chirped pulse amplification(CPA),which made these lasers possible,we celebrate by providing a comprehensive update of the current status of ultra-high-power lasers and demonstrate how the technology has developed.We are now in the era of multi-petawatt facilities coming online,with 100 PW lasers being proposed and even under construction.In addition to this there is a pull towards development of industrial and multi-disciplinary applications,which demands much higher repetition rates,delivering high-average powers with higher efficiencies and the use of alternative wavelengths:mid-IR facilities.So apart from a comprehensive update of the current global status,we want to look at what technologies are to be deployed to get to these new regimes,and some of the critical issues facing their development. | Colin N.Danson Constantin Haefner Jake Bromage Thomas Butcher Jean-Christophe FChanteloup Enam A.Chowdhury Almantas Galvanauskas Leonida A.Gizzi Joachim Hein David I.Hillier Nicholas W.Hopps Yoshiaki Kato Efim A.Khazanov Ryosuke Kodama Georg Korn Ruxin Li Yutong Li Jens Limpert Jingui Ma Chang Hee Nam David Neely Dimitrios Papadopoulos Rory R.Penman Liejia Qian Jorge J.Rocca andrey A.Shaykin Craig W.Siders Christopher Spindloe Sándor Szatmári Raoul M.G.M.Trines Jianqiang Zhu Ping Zhu Jonathan D.Zuegel | 2019 | High Power Laser Science and Engineering2019，7，3： | 33 |
| 2 | Inhibition of the B7-H3 immune checkpoint limits tumor growth by enhancing cytotoxic lymphocyte function显示文摘在肿瘤和免疫系统之间的相互作用仍然糟糕被理解。重要临床的回答在对 CTLA4 和 PD-1/PD-L1 检查点与抗体对待的癌症病人被完成了;然而,仅仅病人的小部分对治疗作出回应,显示需要探索为癌症治疗的另外的 co 禁止的分子。B7-H3, B7 总科的一个成员,被我们以前显示出禁止 T 房间激活和 autoimmunity。在这研究,我们在肿瘤免疫分析了 B7-H3 的功能。B7-H3 的表示在多重肿瘤线,渗入肿瘤的树枝状的房间,和巨噬细胞被发现。与对抗抗体对待到 B7-H3 的 B7-H3-deficient 老鼠或老鼠显示出多重肿瘤的减少的生长,它取决于 NK 和 CD8 + T 房间。与细胞毒素的淋巴细胞表示的通常认为的受体, B7-H3 禁止了他们的激活,并且它的缺乏在忍受肿瘤的鼠标导致了增加的细胞毒素的淋巴细胞功能。B7-H3 和 PD-1 的联合封锁导致了迟了阶段的肿瘤的进一步提高的治疗学的控制。一起拿,我们的结果显示 B7-H3 检查点可以对癌症为免疫疗法用作一个新奇目标。 | Young-hee Lee Natalia Martin-Orozco Peilin Zheng Jing Li Peng Zhang Haidong Tan Hyun Jung Park Mira Jeong Seon Hee Chang Byung-Seok Kim Wei Xiong Wenjuan Zang Li Guo Yang Liu Zhong-jun Dong Willem W Overwijk Patrick Hwu Qing Yi Larry Kwak Zhiying Yang Tak W Mak Wei-Li Laszlo G Radvanyi Ling Ni Dongfang Liu Chen Dong | 2017 | Cell Research2017，27，8： | 29 |
| 3 | Expression and regulation of IL-22 in the IL-17.producing CD4+T lymphocytes显示文摘IL-22 是在工作对感染支持纸巾的天生的免疫的 IL-10 家庭的新奇 cytokine。尽管 CD4+ 助手 T 淋巴细胞(TH ) 作为 IL-22 的来源被发现,这 cytokine 的规定糟糕被理解。这里,我们证明 IL-22 被也做 IL-17 的 TH 房间的一个新奇子集在 mRNA 和蛋白质层次表示。IL-22 和 IL-17 被发现被即时 PCR 以及 ELISA 分析被 TGFbeta 和 IL-6 并列地在 TH 区别期间调整。然而, IL-22 不调整 TH 区别;外长的 IL-22 或一个 IL-22 对手没在 TH 区别上有效果。这些数据表明 IL-17-producing T 房间表示的新奇 cytokine,并且建议在组织发炎和自体免疫的疾病表明小径的 IL-22 和 IL-17 的相互作用和协同作用。 | Yeonseok Chung Xuexian Yang Seon Hee Chang Li Ma Qiang Tian Chen Dong | 2006 | Cell Research2006，16，11： | 20 |
| 4 | Modeling hot deformation behavior of low-cost Ti-2Al-9.2Mo-2Fe beta titanium alloy using a deep neural network显示文摘Ti-2 Al-9.2 Mo-2 Fe is a low-cost β titanium alloy with well-balanced strength and ductility, but hot working of this alloy is complex and unfamiliar. Understanding the nonlinear relationships among the strain,strain rate, temperature, and flow stress of this alloy is essential to optimize the hot working process.In this study, a deep neural network(DNN) model was developed to correlate flow stress with a wide range of strains(0.025–0.6), strain rates(0.01–10 s^-1) and temperatures(750–1000℃). The model, which was tested with 96 unseen datasets, showed better performance than existing models, with a correlation coefficient of 0.999. The processing map constructed using the DNN model was effective in predicting the microstructural evolution of the alloy. Moreover, it led to the optimization of hot-working conditions to avoid the formation of brittle precipitates(temperatures of 820–1000℃ and strain rates of 0.01-0.1 s^-1). | Cheng-Lin Li P.L.Narayana N.S.Reddy Seong-Woo Choi Jong-Taek Yeom Jae-Keun Hong Chan Hee Park | 2019 | Journal of Materials Science & Technology2019，35，5： | 7 |
| 5 | Activation-Tagged Suppressors of a Weak Brassinosteroid Receptor Mutant显示文摘Brassinosteroids (BR ) 是与植物生长素 synergistically 行动调整的重要植物荷尔蒙许多植物发展、生理的过程。在过去的十年,基因、生物化学的研究揭示了依靠蛋白质 phosphorylation 播送 BR 信号进原子核的一条线性发信号小径,改变支持植物生长的几百基因的表示。我们进行了一幅标注激活的基于的 suppressor 屏幕寻找 Arabidopsis 基因由插入的 35S enhancer 元素的 overexpressed,能压制弱 BR 受体异种 bri1-301 的矮子显型。这幅屏幕识别了六主导的标注激活的 bri1 suppressors (atbs-Ds ) 的一个总数。用一条 plasmid 营救途径,我们发现在四 atbs-D 异种(到 atbs6-D 的 atbs3-D ) 的 bri1-301 抑制效果被涉及色氨酸依赖者植物生长素生合成的一个丝兰属植物基因想法的 overexpression 引起。有趣地,三标注激活的丝兰属植物基因属于从 11 已知的 Arabidopsis 丝兰属植物基因包括二个另外的成员的丝兰属植物 IIA 亚科。另外,我们的分子的研究在在 atbs2-D 带 BR biosynthetic 基因的一个区域在 atbs1-D 和 T-DNA 插入在基本 helix-loop-helix 基因附近揭示了 T-DNA 插入。这些 atbs-D 异种的进一步的研究能导致表明过程和 BRauxin 相互作用的 BR 的更好的理解。 | Bin Kang Hao Wang Kyoung Hee Nam Jiayang Li Jianming Li | 2010 | Molecular Plant2010，3，1： | 5 |
| 6 | Effects of water-based binders on electrochemical performance of manganese dioxide cathode in mild aqueous zinc batteries显示文摘In the majority of rechargeable batteries including lithium-ion batteries,polyvinylidene fluoride(PVdF)binders are the most commonly used binder for both anode and cathode.However,using PVdF binder requires the organic solvent of N-methyl-2-pyrrolidone which is expensive,volatile,combustible,toxic,and has poor recyclability.Therefore,switching to aqueous electrode processing routes with non-toxic binders would provide a great leap forward towards the realization of ideally fully sustainable and environmentally friendly electrochemical energy storage devices.Various water-soluble binders(aqueous binders)were characterized and compared to the performance of conventional PVdF.Our study demonstrates that the electrochemical performance of Zn/MnO_(2) aqueous batteries is significantly improved by using sodium carboxymethyl cellulose(CMC)binder.In addition,CMC binders offer desirable adhesion,good wettability,homogeneous material distribution,and strong chemical stability at certain pH levels(3.5-5)without any decomposition for long-cycle life. | Hee Jung Chang Ismael A.Rodriguez-Pere Matthew Fayette Nathan L.Canfield Huilin Pan Daiwon Choi Xiaolin Li David Reed | 2021 | Carbon Energy2021，3，3： | 5 |
| 7 | Spatially Bandgap-Graded Mo S2(1-x)Se2x Homojunctions for Self-Powered Visible–Near-Infrared Phototransistors显示文摘Ternary transition metal dichalcogenide alloys with spatially graded bandgaps are an emerging class of two-dimensional materials with unique features,which opens up new potential for device applications.Here,visible–near-infrared and self-powered phototransistors based on spatially bandgap-graded MoS2(1−x)Se2x alloys,synthesized by a simple and controllable chemical solution deposition method,are reported.The graded bandgaps,arising from the spatial grading of Se composition and thickness within a single domain,are tuned from 1.83 to 1.73 eV,leading to the formation of a homojunction with a builtin electric field.Consequently,a strong and sensitive gate-modulated photovoltaic effect is demonstrated,enabling the homojunction phototransistors at zero bias to deliver a photoresponsivity of 311 mA W−1,a specific detectivity up to^10^11 Jones,and an on/off ratio up to^10^4.Remarkably,when illuminated by the lights ranging from 405 to 808 nm,the biased devices yield a champion photoresponsivity of 191.5 A W−1,a specific detectivity up to^1012 Jones,a photoconductive gain of 10^6–10^7,and a photoresponsive time in the order of^50 ms.These results provide a simple and competitive solution to the bandgap engineering of two-dimensional materials for device applications without the need for p–n junctions. | Hao Xu Juntong Zhu Guifu Zou Wei Liu Xiao Li Caihong Li Gyeong Hee Ryu Wenshuo Xu Xiaoyu Han Zhengxiao Guo Jamie HWarner Jiang Wu Huiyun Liu | 2020 | Nano-Micro Letters2020，12，2： | 4 |
| 8 | Uric Acid Stimulates Monocyte Chemoattractant Protein-1 Production in Vascular Smooth Muscle Cells Via Mitogen-Activated Protein Kinase and Cyclooxygenase-2显示文摘 | John Kanellis Susumu Watanabe Jin H. Li Duk Hee Kang Ping Li Takahiko Nakagawa Ann Wamsley David Sheikh-Hamad Hui Y. Lan Lili Feng Richard J. Johnson | 2003 | Hypertension: Journal of the American Heart Association2003，，6： | 2 |
| 9 | Histone deacetylase 6 plays a roleas a distinct regulator of diverse celluar processes 显示文摘 | Li YX Don^iee S So Hee K | 2012 | FEBS Journal2012，280，3： | 1 |
| 10 | A cross -sectional and diurnal study of thrombogenesis among patients with chronic atrial fibrillation 显示文摘 | Li -Saw- Hee FL blann AD Lip GY | 2000 | J Am Coil Cardiol2000，35，： | 1 |
| 11 | Weak - base anion exchange membranes by amination of chlorinated polypropylene with polyethyleneimine at low temperatures 显示文摘 | Joo - Hee Hong Dan Li Huanting Wang | 2008 | Journal of Membrane Science2008，，318： | 1 |
| 12 | Collective Consulta- tion and Industrial Relations in China 显示文摘 | Clarke Simon Chang -Hee Lee and Qi Li | 2004 | British Journal of In- dustrial Relations2004，42，2： | 1 |
| 13 | Bio-inspired untethered fully soft robots in liquid actuated by induced energy gradients显示文摘Soft robotics with new designs,fabrication technologies and control strategies inspired by nature have been totally changing our view on robotics.To fully exploit their potential in practical applications,untethered designs are preferred in implementation.However,hindered by the limited thermal/mechanical performance of soft materials,it has been always challenging for researchers to implement untethered solutions,which generally involve rigid forms of high energy-density power sources or high energy-density processes.A number of insects in nature,such as rove beetles,can gain a burst of kinetic energy from the induced surface-energy gradient on water to return to their familiar habitats,which is generally known as Marangoni propulsion.Inspired by such a behavior,we report the agile untethered mobility of a fully soft robot in liquid based on induced energy gradients and also develop corresponding fabrication and maneuvering strategies.The robot can reach a speed of 5.5 body lengths per second,which is 7-fold more than the best reported,0.69(body length per second),in the previous work on untethered soft robots in liquid by far.Further controlling the robots,we demonstrate a soft-robot swarm that can approach a target simultaneously to assure a hit with high accuracy.Without employing any high energy-density power sources or processes,our robot exhibits many attractive merits,such as quietness,no mechanical wear,no thermal fatigue,invisibility and ease of robot fabrication,which may potentially impact many fields in the future. | Liang Xiong Lyu Fen Li Kang Wu Pan Deng Seung Hee Jeong Zhigang Wu Han Ding | 2019 | National Science Review2019，6，5： | 1 |
| 14 | Biocompatibility of titanium implants modified bymicroarc oxidation and hydroxyapatite coating显示文摘 | Li Long Hao Kim Hae Wom Lee Su Hee | 2004 | Journal of biomedical Materials Research Part A2004，73，： | 1 |
| 15 | BRI1/BAK1, a Receptor Kinase Pair Mediating Brassinosteroid Signaling显示文摘 | Kyoung Hee Nam Jianming Li | 2002 | Cell2002，，2： | 1 |
| 16 | Proteasome inhibition improves diaphragm function in congestive heart failure rats显示文摘 | van Hees H W Li Y P Ottenheijm C A | 2008 | Am J Physiol Lung Cell Mol Physiol2008，294，6： | 1 |
| 17 | Bioactivity guided isolation of cytotoxic constituents of Brucea javanica collected in Vietnam显示文摘 | Li Pan Young WC Hee BC | 2009 | Bioorg & Medicinal Chem2009，17，6： | 1 |
| 18 | Uric Acid Stimulates Monocyte Chemoattractant Protein-1 Production in Vascular Smooth Muscle Cells Via Mitogen-Activated Protein Kinase and Cyclooxygenase-2显示文摘 | John Kanellis Susumu Watanabe Jin H. Li Duk Hee Kang Ping Li Takahiko Nakagawa Ann Wamsley David Sheikh-Hamad Hui Y. Lan Lili Feng Richard J. Johnson | 2003 | Hypertension: Journal of the American Heart Association2003，，6： | 1 |
| 19 | The impact of parental migration on health status and health behaviours among left be- hind adolescent school children in China显示文摘 | Yang Gao Li Ping Li Jean Hee Kim | 2010 | BMC Public Health2010，，10： | 1 |
| 20 | Effects of dual component microcapsules of resin and curi-ng agent on the self-healing efficiency of epoxy 显示文摘 | Qi Li Siddaramaiah Nam Hoon Kim David Huid Joong Hee Lee | 2013 | CompositesPart B: Engineering2013，55，： | 1 |
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