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| 1 | Function of apoptosis and expression of the proteins Bcl-2,p53 and C-myc in the development of gastric cancer显示文摘INTRODUCTIONIn China ,the incidence and mortality of gastric cancer rank the second among all cancers. Recent development of cancer [1-20].The aim of this study was investigat the insight of apoptosis and bcl-2, p53 and C-myc protein expression in the development of gastric cancer . | An Gao Xu Shao Guang Li Ji Hong Liu Ai Hua Gan Research Laboratory of Digestive Disease,Huizhou Central People’s Hospital,Huizhou 516001,Guangdong Province,ChinaDr.An Gao Xu graduated from Guangdong Medical College in 1984.He is an associate physician-in-chief,specializing in the research and treatment of gastrointestinal and liver tumors.He has published 24 papers and 1 book. | 2001 | World Journal of Gastroenterology2001，7，3： | 91 |
| 2 | Mycoplasma infections and different human carcinomas显示文摘AIM To explore relationships between human carcinomas and mycoplasma infection.METHODS Monoclonal antibody PD4, which specifically recognizes a distinct protein from mycoplasma hyorhinis, was used to detect mycoplasma infection in different paraffinembedded carcinoma tissues with immunohistochemistry. PCR was applied to amplify the mycoplasma DNA from the positive samples for confirming immunohistochemistry.RESULTS Fifty of 90 cases (56%) of gastric carcinoma were positive for mycoplasma hyorhinis. In other gastric diseases, the mycoplasma infection ratio was 28% (18/49) in chronic superficial gastritis, 30% (14/ 46) in gastric ulcer and 37% (18/ 49) in intestinal metaplasia. The difference is significant with gastric cancer (X2=12.06, P<0.05). In colon carcinoma, the mycoplasma infection ratio was 55.1% (32/58), but it was 20.9% (10/49) in adenomarous polyp (X2=13.46, P<0.005).Gastric and colon cancers with high differentiation had a higher mycoplasma infection ratio than those with low differentiation (P< 0.05). Mycoplasma infection in esophageal cancer, lung cancer, breast cancer and glioma was 50.9% (27/53), 52.6% (31/ 59), 39.7%(25/63) and 41% (38/91), respectively. The mycoplasma DNA was successfully amplified with the DNA extracted from the cancer tissues that were positive for mycoplasma infection (detected with antibody PD4).CONCLUSION There was high correlation between mycoplasma infection and different cancers, which suggests the possibility of an association between the two. The mechanism involved in oncogenesis by mycoplasma remains unknown. | Su Huang Ji You Li Jan Wu Lin Meng Cheng Chao Shou Beijing Institute for Cancer Research, Peking University School of Oncology, Beijing 100034. ChinaSu Huang, received B. A from Jiangxi Medical College of China in 1994. Now she is a graduate student pursuing a Ph. D degree at the Peking University School of Oncology. | 2001 | World Journal of Gastroenterology2001，7，2： | 18 |
| 3 | A new rat model of portal hypertension induced by intraportal injection of microspheres显示文摘AnewratmodelofportalhypertensioninducedbyintraportalinjectionofmicrospheresLIXiangNong1,ISBenjamin2andBAlexander2Subjecthead... | LI Xiang-Nong IS Benjamin B Alexander | 1998 | World Journal of Gastroenterology1998，4，1： | 4 |
| 4 | “Color Revolutions” and Beyond显示文摘“Color revolutions” (or “orange revolutions”) broke out in some of the Commonwealth of Independent States in the past couple of years, reminiscent of the drama of disintegration of the former Soviet bloc at the turn of the 1990s. Why those upheavals came hot on the heels of the Soviet collapses merely a dozen or so years ago? Are we expecting more domino effects down the road? What geographical repercussions will they spark? A panel discussion was held on the topic and their views published in the journal. | Dr. Ji Zhiye is Research Professor and Assistant President of China Institutes of Contemporary International Relations (CICIR), and Director of the Institute of Russian Studies concurrently. He is editor and coauthor of many books including Russian Think-Tanks on Foreign Affairs and The Shanghai Cooperation Organization——New Security and New Mechanism. Dr. Xu Tao is Research Professor and Deputy Director of the Institute of Russan Studies, CICIR. Jiang Li is Associate Research Professor of the Institute of Russian Studies, CICIR. Da Wei is Assistant Director of the Institute of American Studies, CICIR. Dr. Chen Xiangyang is Deputy Director of the Center for Strategic Studies, CICIR. Ding Xiaoxing is Assistant Research Professor of the Institute of Russian Studies, CICIR. | 2005 | Contemporary International Relations2005，15，6： | 3 |
| 5 | Safety and efficacy of leflunomide in the treatment of lupus nephritis refractory or intolerant to traditional immunosuppressive therapy: an open label trial 显示文摘 | Tam IS Li EK Wong CK | 2006 | Ann Rheum Dis2006，65，3： | 1 |
| 6 | Epidemiologic data of renal diseases from a single unit in China : analysis basedon 13,519 renal biopsies 显示文摘 | Li IS Liu ZH | 2004 | Kidney Int2004，66，3： | 1 |
| 7 | Association between interleukin-l jj C (3953/4)T polymorphism and chronic periodontitis: evidence from a meta-analysis显示文摘 | Deng IS Qin P Li XX | 2013 | Hum Immunol2013，74，3： | 1 |
| 8 | Pharmacological preconditioning with low-dose cyclosporine or FK506 red uces subsequent ischemia/reperfusion injury in rat kidney 显示文摘 | Ahn HJ Han HJ Kim WY Li C Shin MJ Kim SK Park JH Kim YS Moon IS Bang BK | 2001 | Transplantation2001，72，11： | 1 |
| 9 | Acrylic Acid-RGD as a Biomimetic Surface Modifier for Poly(ethylene terephthalate)显示文摘The development of the blood compatibility is important to biomaterials.The attachment of human umbilical vein endothelial cells (HUVECs) on substrates that had been covalently grafted with the cell adhesion peptides Arg Gly Asp(RGD) was investigated. The immobilization of the peptide sequences at the surfaces of biomaterials, such as poly(ethylene terephthalate) (PET), is difficult due to an absence of functional groups to support covalent attachment. It is demonstrated a novel method to overcome this problem, by attach the RGD to acrylic acid(AAC), which immobilizes the sequence through adsorption at the PET surface. When coated by AAC RGD, the human umbilical vein endothelial cells (HUVECs) seeded upon the modified PET showed a marked increase in spreading over unmodified PET. The peptides were grafted using two steps: conjugation of AAC with PET film; reaction with PET AAC and immobilization of cell binding peptides RGD. The RGD grafted surface was characterized by X ray photoelectron spectroscopy(XPS) and contact angle measurements. Cell spreading is observed by optional microscopy and scanning electron microscope(SEM). Potentially, this is a feasible method of surface modification that can design many different types of biomaterials with a variety of biomolecules. | QIU Kai 1 , WAN Chang xiu 1 , CHEN Xin 1,LI Tian quan 2 This materials is based upon the work supported under the National Nature Science Fund project of China(29874022) 1 Department of Polymer Science and Engneering, Sichuan University,Chengdu 610065,China 2 Department of Chemistry, Sichuan University,Chengdu 610065,China | 2003 | Chinese Journal of Biomedical Engineering(English Edition)2003，12，1： | 1 |
| 10 | Epidemiologic data of renal diseases from a single unit in China: analysis based on 13,519 renal biopsies显示文摘 | Li IS Liu ZH | 2004 | Kid- ney Int2004，66，3： | 1 |
| 11 | The relationship between intrahepatic portal systemic shunts and microsphere induced portal hypertension in the rat liver显示文摘 | Li X Benjamin IS Alexander B | 1998 | Gut1998，42，1： | 1 |
| 12 | The relationship between intrahepatic portal systemic shunts and microsphere induced portal hypertention in the rat liver显示文摘 | X Li IS Benjamin B Alexander | 1998 | Gut1998，42，： | 1 |
| 13 | Location and function of intrahepatic shunts in anaesthetized rats显示文摘 | X Li IS Benjamin R Naftalin | 2003 | Gut2003，52，9： | 1 |
| 14 | The rela-tionship between intrahepatic portal systemic shunts and microsphere induced portal hypertension in the rat liver显示文摘 | LI X BENJAMIN IS ALEXANDER B | 1998 | Gut1998，42，2： | 1 |
| 15 | Reproducible production of thioacetamide-induced macronodular cirrhosis in the rat with no mortality显示文摘 | Li X Benjamin IS Alexander B | 2002 | J Hepatol2002，36，4： | 1 |
| 16 | HIV-1 Tat-mediated protein transduction of Cu, Zn-superoxide dismutase into pancreatic β cells in vitro and in vivo 显示文摘 | Eum WS Choung IS LI MZ | 2004 | Free Radic Biol Med2004，37，3： | 1 |
| 17 | Clinical application prospects of gastric pacing for treating postoperative gastric motility disorders 显示文摘 | Li FY Jiang IS Cheng JQ | 2007 | J Gastroenterol Hepatol2007，22，12： | 1 |
| 18 | Increased adrenomedullin expression in lungs in endotoxaemia 显示文摘 | Cheung BM Hwang IS Li CY | 2004 | J Endocrin2004，181，2： | 1 |
| 19 | Epidemiologic data of Renal diseases from a single unit in China:Analysis based on 13519 renal bi- opsies 显示文摘 | Li IS Liu ZH | 2004 | Kidney Int2004，66，3： | 1 |
| 20 | Soft Power Building and China's Peaceful Development显示文摘In today’s world, competition bolls down to that of overall National strength. A country’s development and strength are reflected not only in hard power including economic growth, scientific and technological advancement and military power enhancement but also in soft power including culture and ideology, spiritual pursuit and moral strength. In recent years, major powers | Li Jie is Deputy Director of the Department of Policy Planning of the Ministry of Foreign Affairs of China. | 2006 | China International Studies2006，26，4： | 1 |
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