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62篇 您的检索式:作者名="Lewis TM"
    题名 作者 年代 出处 被引量
1应用Rho激酶抑制剂对大鼠阴茎勃起的作用显示文摘目的 :探讨将RhoA/Rho激酶抑制剂Y 2 76 32涂抹于阴茎白膜表面以及阴茎龟头皮肤表面有无促进阴茎勃起的作用及其对体循环的影响。 方法 :2 0只成年雄性SD大鼠 ,体重为 2 5 0~ 30 0g ,随机分为实验组和对照组。全身麻醉后颈动脉和海绵体插管连续监测平均动脉压 (MAP)和阴茎海绵体内压 (CCP)的变化。寻找盆腔星状神经节(MPG)并以系列电刺激诱发勃起。向海绵体白膜表面及阴茎龟头皮肤表面涂抹Y 2 76 32 ,观察用药前后阴茎勃起的改变及MAP的改变。 结果 :将Rho激酶抑制剂Y 2 76 32涂抹于大鼠阴茎白膜表面和阴茎龟头皮肤表面均可促进在无阴茎支配神经电刺激下发生勃起 (ICP/MAP明显升高 ) ,在系列电刺激MPG时用药后发生的勃起反应较用药前亦明显增强。表面用药后还发现大鼠体循环血压有不同程度的降低。 结论 :阴茎皮肤表面应用Rho激酶抑制剂是一种安全有效的ED治疗方法 。戴玉田 孙则禹 Chitaley K Webb RC Mills TM Lewis RW 2004中华男科学杂志2004,10,8:5
2Mechanisms of disease in hemorrhagic fever with renal syndrome 显示文摘Cosgriff TM Lewis RM 1991Kidney Int1991,35,:1
3Vasoconstriction,RhoA/Rho-kinase and the erectile response显示文摘Mills TM Lewis RW Wingard CJ 2003Int J Impot Res2003,15,5:1
4Vasoconstrictors in erectile physiology显示文摘Mills TM Chitaley K Lewis RW 2001Int J Impot Res2001,13,5:1
5Nitric oxide inhibits RhoA/Rho-kinase signaling to cause penile erection显示文摘Mills TM Chitaley K Lewis RW 2002Eur J Pharmacol2002,439,13:1
6Anterior proliferative vitreoretinopathy显示文摘Lewis H Aaberg TM 1988Am J Ophthalmol1988,105,3:1
7Causes of failure after initial vitreoretinal surgery for severe proliferative vitreoretinopathy 显示文摘Lewis H Aaberg TM Abrams GW 1991Am J Ophthalmol1991,111,:1
8Anterior proliferative vitreoretinopathy显示文摘Lewis H Aaberg TM 1988Am J Ophthalmol1988,105,3:1
9A comparison of skill acquisition and transfer in single incision and multi-port laparoscopic surgery显示文摘Kwasnicki RM Aggarwal R Lewis TM 0,,2:1
10Causes of failure after repeat vitreoretinal surgery for recurrent proliferative vitreoretinopathy 显示文摘Lewis H Aaberg TM 1991Am J Ophthalmol1991,111,:1
11A multivariate analysis of serum nutrient levels and lung function显示文摘McKeever TM Lewis SA Smit HA 2008Respir Res2008,29,9:1
12The predictive value of hemodynamic studies in preclinical ischemic necrosis of bone 显示文摘Zizic TM Lewis CG Marcoux C 1989J Rheumatol1989,16,:1
13Early exposure to infections and antibiotics and the incidence of allergic disease:a birth cohort study with the West Midlands General Practice Research Database显示文摘McKeever TM Lewis SA Smith C 2002J Allergy Clin Immunol2002,109,1:1
14Effect of subtoxic concentrations of metal ions on NFkappaB activation in THP-1 human monocytes显示文摘Lewis JB Randol TM Lockwood PE ct al 2003J Biomcd Mater Res A2003,64,2:1
15Inhibition of tonic contraction--a novel way to approach erectile dysfunction显示文摘Mills TM Lewis RW Wingard CJ 2002J Androl2002,23,5:1
16A comparison of skill acquisition and transfer in single incision and multi-port laparoscopic surgery显示文摘Kwasnicki RM Aggarwal R Lewis TM 0,,02:1
17Nitric oxide inhibits RhoA/Rho-kinase signaling to cause penile erection 显示文摘Mills TM Chitaley K Lewis RW 2002Eur J Pharmacol2002,439,13:1
18Effect of androgens on penile tissue 显示文摘Lewis RW Mills TM 2004Endocrine2004,23,23:1
19Early exposure to infections and antibiotics and the incidence of allergic disease: a birth cohort study with the West Midlands General Practice Research Database 显示文摘McKeever TM Lewis SA Smith C 2002J Allergy Clin Immunol2002,109,1:1
20Mechanisms of toxicity of di (2-ethylhexyl) phthalate on the reproductive health of male zebrafish显示文摘Uren-Webster TM Lewis C Filby AL 0,,03:1
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