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| 1 | A light-harvesting siphonax-anthin-chlorophyll a/b-protein complex of marine green alga, Bryopsis corticulans显示文摘A light-harvesting chlorophyll a/b-protein complex (LHCP) was isolated directly from thylakoid mem-branes of marine green alga, Bryopsis corticulans, by two consecutive runs of liquid chromatography. The trimeric form of the light-harvesting complex has been obtained by sucrose gradient ultracentrifugation. The result of SDS- PAGE shows that the light-harvesting complex is composed of at least five apoproteins in which a protein with apparent molecular weight of about 31 kD was never found in the ma-jor light-harvesting complex (LHC Ⅱ) from higher plants. The isolated Bryopsis corticulans light-harvesting complex contains a specific carotenoid, siphonaxanthin, as well as chlorophyll (Chl) a, Chl b, neoxanthin and violaxanthin. Si-phonaxanthin which is present in the light-harvesting sipho-naxanthin-chlorophyll a/b-protein complex of Bryopsis corticulans is responsible for enhanced absorption in the blue-green region (530 nm). Efficient energy transfer from both siphonaxanthin and Chl b to Chl a in Bryopsis corticu-lans LHCP, which has similar absorption and fluorescence emission spectra to those of the lutein-chlorophyll a/b-protein of higher plants, proved that molecular arrangement of the light-harvesting pigments was highly ordered in the Bryopsis corticulans LHCP. The siphonaxanthin-chlorophyll a/b-pro- teins allow enhanced absorption of blue-green light, the pre-dominant light available in deep ocean waters or shaded subtidal marine habitats. | CHENHui SHENShihua HEJunfang LENGJing LILiangbi KUANGTingyun | 2004 | Chinese Science Bulletin2004，49，18： | 2 |
| 2 | The cyclooxygenase 2 inhibitor celecoxib blocks phosphorylation of Akt and induces apoptosis in human cholangiocarcinoma cells 显示文摘 | WuT LengJ HanC | 2004 | Mol Cancer Ther2004，3，： | 1 |
| 3 | Determinationofaflatoxin(AF)G2,B2andB1in72batchesofShujinHuoxuepillsbyHPLCwithpost-columnphotochemicalderivation显示文摘 | XIEJ YANGHL LENGJ etal G1 | 2014 | 药物分析杂志2014，34，3： | 1 |
| 4 | Carcinosarcoma arising from atypical en?dometriosis in a cesarean section scar显示文摘 | LengJ LangJ Guo L | 2006 | IntJ Gynecol Cancer2006，16，： | 1 |
| 5 | Developmentofpharmacologicaleffectsofrheinanditsconjugates显示文摘 | SuH LengJ WangSD etal | 2011 | 中国药业2011，20，15： | 1 |
| 6 | Effect of Arsenic Trioxide with Various Concentrations on Dendritic Cells in the Conducting Airways of Asthmatic Mice显示文摘To investigate the effect of arsenic trioxide (As2O3 )with three different concentration groups on the distribution and recruitment of dendritic cells(DCs) in the conducting airways of asthmatic mice. Methods: Fifty BALB/c mice were divided into 5 groups at random: control group, asthmatic group, therapeutic groups with low dose(1 mg/kg), moderate dose( 5 mg/lqg) and high dose( 10 mg/kg) of As2O3. The immunohistochomistry, scanning electron microscope and computerized image analysis were applied to detect airway DCs, respectively. Results: We demonstrated from the control mice that all intraepithelial NLDC-145 DCs throughout the respiratory tree cotdd be accounted for a network of cells with dendritic cell morphology, and the density of DCs varied from(500±50) cells/ram^2 epithelial surface in the large airways, to(60±10)cells/mm^2 epithelial surface in the small airways(P<0.05).The DCs characteristic of spiny and long processes were impressively observed by the scanning electron microscope. Comtmred with the control mlce,the density,but not the distribution of NLDC-145 DCs was significantly upregulated in the conducing airways of asthmatic mice(P<0.01) .Compared with the asthmatic mice, the densilies, but not the distributions of NLDC-145 DCs were significantly down regulated in the conducting airways of the thempeutic groups with three varying concentrations of As2O3(P<0.01 )while there were no statistical differences between each other(P>0.05).Conchsion : Our findings suggest that it might be an important therapeutic mechanism of As2 03 to downregulate not the distribution but the density of DCs in the conducting airways of asthmatic mice,and low dose of As203 has potential value in treating asthma. | YINKai-sheng ZHOULin-fu JIXiao-hui LENGJing YANGYu | 2004 | Journal of Nanjing Medical University2004，18，3： | 0 |
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