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13篇 您的检索式：作者名="Leaver N"

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		题名	作者	年代	出处	被引量
	1	Functional genomics reveals increases in cholesterol biosynthetic genes and highly unsaturated fatty acid biosynthesis after dietary substitution of fish oil with vegetable oils in Atlantic salmon (Salmo salar) 显示文摘	Leaver M J Villeneuve L A N Tocher D R	2008	BMC Genom2008，9，：	1
	2	Functional genomics reveals increases in cholesterol biosynthetic genes and highly unsaturated fatty acid biosynthesis after dietary substitution of fish oil with vegetable oils in Atlantic salmon(Salmo salar)显示文摘	Leaver M J Villeneuve L A N Tocher D R	2008	BMC Genomics2008，9，：	1
	3	Dual role of a hydroxyphenyl-benzotriazole UV absorber in the photo oxidation of wool显示文摘	Leaver I H Waters P J Evans N A	1979	Journal of Polymer Science:Polymer Chemistry Edition1979，17，：	1
	4	Fixed bimonthly aflibercept in nave and switched neovascular age-related macular degeneration patients:one year outcomes显示文摘AIM: To determine real life clinical outcomes in poorly responsive and treatment-nave neovascular age-related macular degeneration(nv AMD) patients using bimonthly fixed dosing aflibercept regimen.METHODS: This was a retrospective study of 165 eyes with nv AMD started on aflibercept at Southampton Eye Unit between June 2013 and June 2014. Patients were either switched from pro re nata(PRN) ranibizumab/bevacizumab due to poor response(107 eyes), or treatment- nave( 58 eyes). Patients initially received 3-monthly intravitreal aflibercept injections followed by 2-monthly fixed doses. Clinic visits were scheduled at month 0, 4, 10 and 12. Mean change in best-corrected visual acuity(BCVA) and central retinal thickness(CRT)from baseline were assessed using the Wilcoxon signedrank test. The proportion of patients maintaining BCVA(<15 letters loss) at 12 mo was also evaluated.RESULTS: Mean BCVA change at month 12 was +3.29 and +4.67 letters in the switched and nave aflibercept groups respectively(P <0.01). BCVA was maintained in 95.3% of switched and 96.6% of nave patients. CRT at month 12 showed a decrease of -6.16 μm in the switched group and -35.36 μm in the nave group(P <0.01).Patients previously treated with ranibizumab/bevacizumab had on average received 7.4 ranibizumab/bevacizumab injections over 12.6 mo, attending 10 clinic visits. The fixed dosing aflibercept regimen required an average of 7.1 injections(nave group), 7.5 injections(switched group) and 4 clinic visits per year.CONCLUSION: Fixed bimonthly aflibercept is effective in both treatment-nave and poorly responsive nv AMD patients. Adopting a fixed dosing regimen can reduce patient burden without compromising on outcomes.	Alasdair N Warwick Hannah H Leaver Andrew J Lotery Srini V Goverdhan	2016	International Journal of Ophthalmology(English edition)2016，9，8：	1
	5	Milrinone in ad- vanced heart failure: dose and therapeutic monitor out- side intensive care unit显示文摘	Charisopoulou D Leaver N Banner NR	2014	Angiology2014，65，4：	1
	6	Oral pre:treatment with epigallocatechin gallate in 6-OHDA lesioned rats produces subtle symptomatic relief but neuroprotection 显示文摘	Leaver KR Allbutt HN Creber N J	2009	Brain Res Bull2009，80，6：	1
	7	Coadministration of Itracanazole and Tacrolimus After Thoracic Organ Transplantation 显示文摘	Banerjee R Leaver N Lyster H	2001	Transplant Proc2001，33，：	1
	8	Relationship between quantitative sensory testing and pain or disability in people with spinal pain-a systematic review and meta-analysis显示文摘	Hübscher M Moloney N Leaver A	2013	Pain2013，154，9：	1
	9	Functional genomics reveals increases in cholesterol biosynthetic genes and highly unsaturated fatty acid bi- osynthesis after dietary substitution of fish oil with vegetable oils in Atlantic salmon (Salmo salar) 显示文摘	LEAVER M J VILLENEUVE L A N OBACH A	2008	BMC Genomics2008，9，1：	1
	10	Is monitoring milrinone therapy useful in advanced heart failure显示文摘	Vazir A Leaver N Lyster H	2011	Int J Cardiol2011，149，3：	1
	11	In- creased plasma thioredoxin levels in patients with sepsis: posi tive association with macrophage migration inhibitory factor 显示文摘	LEAVER S K MACCALLUM N S PINGLE V	2010	Intensive Care Med2010，36，2：	1
	12	Is monitoring milrinone therapy useful in advanced heart failure? 显示文摘	Vazir A Leaver N Lyster H	2011	International Journal of Cardiology2011，149，3：	1
	13	Is monitoring milrinone therapy useful in advanced heart faiIure显示文摘	Vazir A Leaver N Lyster H	2011	Int J Cardiol2011，149，3：	1

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