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		题名	作者	年代	出处	被引量
	1	低剂量睾酮疗法降低TM3睾丸间质细胞的氧化损伤显示文摘睾酮替代疗法对老年男性及性腺机能减退症的治疗是有意义的。然而,外源性睾酮对睾丸间质细胞的作用尚不清楚,需要进一步阐明。本研究表明睾酮补充疗法能降低睾丸间质细胞的氧化损伤。本文用睾丸间质细胞TM3作为体外细胞模型。研究发现睾酮剂量为100nmol L-1治疗时可以产生细胞保护作用,但睾酮补充剂量≥500nmol L-1时就会产生细胞毒作用。在睾酮剂量为100nmol L-1治疗时能够显著降低ROS的产生,脂质过氧化物含量,缺氧诱导因子(HIF)-1α的稳定性和活性。睾酮剂量为500nmol L-1时产生的活性氧比100nmol L-1时增加了1.72倍。与对照组相比,睾酮剂量为50nmol L-1时类固醇激素合成急性调节蛋白(STAR)的表达增加了1.58倍(P〈0.01).睾酬补充疗法降低了化学性诱导缺氧。低剂量睾酮补充疗法治疗睾丸间质细胞通过降低ROS和脂质过氧化物,增加StAR蛋白表达,减缓缺氧应激即降低HIF-1α测子的稳定性性产生细胞保护作用。研究中发现当睾酮剂量≥500nmol L-1时,氧化损伤增加。为阐明睾酮替代疗法的效果,需进一步阐明睾丸间质细胞中华酮量效关系受哪种机制调控。	Thomas IS Hwang Tien-Ling Liao Ji-Fan Lin Yi-Chia Lin Shu-Yu Lee Yen-Chun Lai Shu-Huei Kao	2011	Asian Journal of Andrology2011，13，3：	2
	2	Curcumin enhances the im- munosuppressive activity of cyclosporine in rat cardiac allografts and in mixed lymphocyte reactions显示文摘	Chueh SC Lai MK Hu IS	2003	Ransplant Proc2003，35，4：	1
	3	Fluoroquinolone resistance in Mycobacterium tuberculosis isolates: associated genetic mutations and relationship to antimierobial exposure显示文摘	Wang JY Lee LN Lai HC Wang SH Jan IS YU CJ Hsueh PR Yang PC	2007	J Antimierob Chemother2007，59，：	1
	4	Curcumin enhances the immunosuppressive activity of cyclosporine in rat cardiac allografts and in mixed lymphocyte reactions显示文摘	Chueh SC Lai MK Liu IS	2003	Ransplant Proc2003，35，4：	1
	5	Vox Populi on Political Restructuring显示文摘A study shows the general public are keen on political reform and aspire to systemic solutions for corruption and the rich-poor gap.	DAI YUANCHU is executive deputy director of the Global Poll Center,Global Times and WEI LAI is a journalist on Global Times	2011	China Today2011，60，1：	1
	6	Curcumin enhances the immunosuppressive activity of cyelosporine in rat cardiac allografts and in mixed lymphocyte reactions 显示文摘	Anuchapreeda S Lai MK Liu IS	2003	Ransplant Proc2003，35，4：	1
	7	Curcumin enhances the immunosuppressive activity of cyclosporine in rat cardiac allografts and in mixed lymphocyte reactions显示文摘	Lai MK Liu IS	2003	Ransplant Proc2003，35，4：	1
	8	Curcumin enhances the immunosuppressive activity of cyclosporine in rat cardiac allografts and in mixed lymphocyte reactions显示文摘	Chueh SC Lai MK Liu IS	2003	Ransplant Proc2003，35，4：	1
	9	Curcumin enhances the immunosuppressive activity of cyclosporine in rat cardiac allografts and in mixed lymphocyte reactions显示文摘	Chueh SC Lai MK Liu IS	2003	Transplant Proc2003，35，4：	1
	10	IgA nephropathy associated with chronic hepatitis B virus infection in adults: the pathogenetic role of HBsAG显示文摘	Lai KN Lai F M M Tam IS	1989	TheJoumal of pathology1989，157，4：	1
	11	In vivo monitoring of vegf-in- duced retinal damage in the kimba mouse model of retinal neovascu- larization 显示文摘	Ali Rahman IS Li CR Lai CM	2011	Curr Eye Res2011，36，7：	1
	12	GENESIS OF THE ALKALI-RICH PORPHYRIES IN YUNNAN显示文摘GENESISOFTHEALKALI-RICHPORPHYRIESINYUNNANLaiJianqingPengShenglin(InstituteofDiwaTheoryandMetalogeny,CentralSouthUniversityof...	Lai Jianqing Peng Shenglin(Institute of Diwa Theory and Metallogeny, Central South University ofTechnology, Changsha 410083, China)The alkalirich porphyries formed in the structural relaxation epoch of the Himalayan Movement. The tectonic setting and crustal structure in which the rocks formed and the compositional regionization feature of the rocks indicate that the magma formed inside the crust, which is further proved by REE, Sr and Pb isotope data. Combined the aforesaid data with the result of REE inversion, it is suggested as a new opinion that the alkalirich porphyries were the remelting product of the mixture of mantle rocks intrusing into the crust with crustal material.	1996	Journal of Central South University1996，8，1：	0

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