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| 1 | 上皮样胶质母细胞瘤和间变性上皮样多形性黄色星形细胞瘤--同一肿瘤或同一谱系?显示文摘上皮样胶质母细胞瘤和伴有局灶间变的多形性黄色星形细胞瘤具有重叠特征。作者回顾性分析了11例上皮样胶质母细胞瘤和5例多形性黄色星形细胞瘤的免疫组化特征,采用荧光原位杂交技术(FISH)检测EGFR扩增、PNET缺失和ODZ3缺失情况,其中5例用还检测了Ilumina450K甲基化。上皮样胶质母细胞瘤平均发病年龄30.9岁(2~79岁),包括5例儿童病例,男女比为4.5:1。多形性黄色星形细胞瘤的男女比为4:1,平均发病年龄21.2岁(10—38岁),包括2例儿童病例。其中6例上皮样胶质母细胞瘤和2例多形性黄色星形细胞瘤复发(平均复发时间分别为12个月和3.3个月)。 | Alexandrescu S Korshunov A Lai S H 李晓玲(摘译) 王行富(审校) | 2016 | 临床与实验病理学杂志2016,32,1: | 14 |
| 2 | Experimental small bowel preservation using Polysol: A new alternative to University of Wisconsin solution, Celsior and histidine-tryptophan-ketoglutarate solution?显示文摘AIM: To evaluate the potential of Polysol, a newly developed preservation solution, in cold storage of small bowel grafts, compared with the current standards, University of Wisconsin solution (UW), Celsior and histidine-tryptophan-ketoglutarate solution (HTK). METHODS: Male Wistar rats were used as donors. Small bowels were retrieved, flushed and then stored in the respective 4 solutions for 18 h at 4℃. Functional integrity of the grafts was evaluated by isolated reperfusion with oxygenated Krebs-Henseleit buffer at 37℃ for 30 min in all 4 groups. RESULTS: Polysol preservation exhibited the highest tissue ATP concentration and the lowest release of LDH. Malondialdehyde, an index for tissue lipid peroxidation, was also the lowest in Polysol. Tissue oxygen consumption was significantly higher in Polysol than in the others. Of interest, UW-storage promoted 10-fold higher apoptosis than in the others. Moreover, electron microscopy revealed that the mucosal villi/micro-villi formation and the cell organelles, including mitochondria, were both significantly better preserved in Polysol, while deleterious alterations were apparent in the others, most notably in UW. Although Celsior and HTK exhibited the better trend of results than UW in some parameters, but could not reach the over-all superiority to UW.CONCLUSION: Cold storage using Polysol resulted in significantly better integrity and function of small bowel grafts than UW. Hence, Polysol may be a novel alternative for the small bowel preservation. | Lai Wei Koichiro Hata Benedict Marie Doorschodt Reinhard Büttner Thomas Minor René H Tolba | 2007 | World Journal of Gastroenterology2007,13,27: | 9 |
| 3 | GENETIC PROGRAMMING TO PREDICT SKI-JUMP BUCKET SPILLWAY SCOUR显示文摘Researchers in the past had noticed that application of Artificial Neural Networks (ANN) in place of conventional statistics on the basis of data mining techniques predicts more accurate results in hydraulic predictions. Mostly these works pertained to applications of ANN. Recently, another tool of soft computing, namely, Genetic Programming (GP) has caught the attention of researchers in civil engineering computing. This article examines the usefulness of the GP based approach to predict the relative scour depth downstream of a common type of ski-jump bucket spillway. Actual field measurements were used to develop the GP model. The GP based estimations were found to be equally and more accurate than the ANN based ones, especially, when the underlying cause-effect relationship became more uncertain to model. | AZAMATHULLA H. MD GHANI A. AB ZAKARIA N. A LAI S. H CHANG C. K LEOW C. S ABUHASAN Z | 2008 | Journal of Hydrodynamics2008,20,4: | 4 |
| 4 | Design optimization of a slotless PM brushless motor with helical edge wound laminations for rim driven thrusters显示文摘 | Sharkh S M Lai S H | 2010 | High Technology Letters2010,16,1: | 3 |
| 5 | An ordinal optimization based bidding strategy for electric power suppliers in the daily energy market显示文摘 | Guan X H HoYC(Larry) Lai F | 2001 | IEEE Trans on Power Svstems2001,16,4: | 2 |
| 6 | On the dexterity of robotics manilulators-service angle显示文摘 | Yang D C H Lai Z C | 1985 | ASME Journal of Mechanisms Transmissions and Automation in Design1985,107,3: | 2 |
| 7 | A molecular roadmap for induced multi-lineage transdifferentiation of fibroblasts by chemical combinations显示文摘 | Xiaoping Han Hao Yu Daosheng Huang Yang Xu Assieh Saadatpour Xia Li Lengmei Wang Jie Yu Luca Pinello Shujing Lai Mengmeng Jiang Xueying Tian Fen Zhang Yanhong Cen Yuko Fujiwara Wei Zhu Bin Zhou Tianhua Zhou Hongwei Ouyang Jianan Wang Guo-Cheng Yuan Shumin Duan Smart H Orkin Guoji Guo | 2017 | Cell Research2017,27,3: | 2 |
| 8 | Mathematical modelling of elliptic helicoid screw transmission systems显示文摘 | Wu D S Lai H Y Chen C K | 2002 | Proceedings of the Institution of Mechanical Engineers Part B: Journal of Engineering Manufacture2002,216,2: | 1 |
| 9 | Management of recurrent cervical cancer显示文摘 | Lai C H | 2004 | Chang Gung Med J2004,27,10: | 1 |
| 10 | Matrix profile and wavefront reduction based on the graph theory and wavefront minimization显示文摘 | Lai Y C Weingarten V I Eshraghi H | 1996 | International Journal for Numerical Methods in Engineering1996,39,7: | 1 |
| 11 | Using single family in reforestation: gene diversity concerns 显示文摘 | Kang K S Lai H L Lindgren D | 2002 | Silvae Genetica2002,51,23: | 1 |
| 12 | Neural network models for product image design显示文摘 | Lin Y C Lai H H Yeh C H | 2004 | Knowledge-Based Intelligent Information and Engineering Systems2004,,3215: | 1 |
| 13 | Chin Tradit Pat Med 显示文摘 | Liu Z Q Lai X P Wu Y H | 2001 | 23(8): 550-5522001,23,8: | 1 |
| 14 | Elevated C-reactive protein levels are associated with endothelial dysfunction in chronic cocaine users 显示文摘 | Meng QY Lima JA Lai H | 2003 | lnt J Cardiol2003,88,23: | 1 |
| 15 | 显示文摘 | Wu J M Lai C H | 1991 | J Am Ceram Soc1991,74,2: | 1 |
| 16 | In vitro neutralization by monoclonal antibodies against yellow grouper nervous necrosis virus(YGNNV) and immunolocalization of viru infection in yellow grouper,Epinephelus awoara (Temminck & Schlegel)显示文摘 | Lai Y S Chiu H C Murali S | 2001 | J Fish Dis2001,24,: | 1 |
| 17 | Precision modeling of form errors for cylindricity evaluation using genetic algorithms显示文摘 | Lai H Y Jywe W Y Chen C K and Liu C H | 2000 | Precision Engineering2000,24,4: | 1 |
| 18 | Effects of temperature and salinity on oxygen consumption and ammonia-N excretion of juvenile Penaeus japonicus Bate显示文摘 | CHEN J C LAI S H | 1993 | Journal of Experimental Marine Biology and Ecology1993,165,: | 1 |
| 19 | Nitrogen loss in a nitrifying rotating contactor treating ammonium-rich leachate without organic carbon显示文摘 | Siegrist H Reithaar S Lais P | 1998 | Water Sci Technol1998,37,45: | 1 |
| 20 | Antitumor activity of 3,5,4'-trimethoxystilbene in COLO 205 cells and xeno- grafts in SCID mice 显示文摘 | Pan M H Gao J H Lai C S | 2008 | Molecular Carcinog2008,47,3: | 1 |