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	题名	作者	年代	出处	被引量
1	emerging role of the β-catenin-PPARγ axis in the pathogenesis of colorectal cancer显示文摘Multiple lines of evidence indicate that Wnt/β-catenin signaling plays a fundamental role in colorectal cancer(CRC)initiation and progression.Recent genome-wide data have confirmed that in CRC this pathway is one of the most frequently modified by genetic or epigenetic alterations affecting almost 90%of Wnt/β-catenin gene members.A major challenge is thus learning how the corrupted coordination of this pathway is tied to other signalings to enhance cell growth.Peroxisome proliferator activated receptorγ(PPARγ)is emerging as a growth-limiting and differentiation-promoting factor.In tumorigenesis it exerts a tumor suppressor role and is potentially linked with the Wnt/β-catenin pathway.Based on these results,the identification of new selective PPARγmodulators with inhibitory effects on the Wnt/β-catenin pathway is becoming an interesting perspective.Should,in fact,these molecules display such properties,new research avenues would be opened aimed at developing new molecular targeted drugs.Herein,we review the basic principles and present new hypotheses underlying the crosstalk between Wnt/β-catenin and PPARγsignaling.Furthermore,we discuss the advances in our understanding as to how their altered regulation can culminate in colon cancer and the efforts aimed at designing novel PPARγagonists endowed with Wnt/β-catenin inhibitory effects to be used as therapeutic and/or preventive agents.	Lina Sabatino Massimo Pancione Carolina Votino Tommaso Colangelo Angelo Lupo Ettore Novellino Antonio Lavecchia Vittorio Colantuoni	2014	World Journal of Gastroenterology2014，20，23：	8
2	Kinetic study of hydrogen peroxidedecomposition by catalase in a flow- mix microcalorimetricsystem 显示文摘	Fidaleo M Lavecchia R	2003	Thermochimica Acta2003，402，12：	1
3	Combined effect of tobacco and alcohol on laryngeal cancer risk:a case-control study显示文摘	Talamini R Bosetti C Lavecchia C	2002	Cancer Causes Control2002，13，10：	1
4	Oral contraceptives and ovarian cancer: an update, 1998-2004 显示文摘	LaVecchia C	2006	Eur J Cancer Prey2006，15，2：	1
5	Ex- perimental study aiming to enhance the surface finish of fused deposition modeled parts 显示文摘	Galantucci L M Lavecchia F Percoco G	2009	CIRP Annals-Manufacturing Technology2009，58，1：	1
6	1 Right ventricular function predicts transplant- free survival in idiopathic dilat- ed cardiomyopathy 显示文摘	LaVecchia L Varotto L Zanolla L eta	2006	J Cardiovasc Med ( Hagerstown)2006，7，9：	1
7	Fluoride removal from water by adsorption on a high alumina content bauxite 显示文摘	Roberto Lavecchia Franco Medici Luigi Piga	2012	Chemical Engineering Transactions2012，26，：	1
8	Role of HRCT in the identification of atypical pulmonary mycobacteriosis 显示文摘	D'Arienzo P Giampalma E Lavecchia MA	2002	Radiol Med (Torino)2002，103，3：	1
9	Virtual screening strategies in drug discovery: a critical review显示文摘	Lavecchia A Di Giovanni C	2013	Curr Med Ghem2013，20，23：	1
10	Cdc25A and B dual-specificity phosphatase inhibitors: potential agents for cancer therapy 显示文摘	Lavecchia A Di Giovanni C Novellino E	2009	Curt Med Chem2009，16，15：	1
11	Enzyme-assisted extraction of lycopene from tomato processing waste 显示文摘	Antonio Zuorro Marcello Fidaleo Roberto Lavecchia	2011	Enzyme and Microbial Technology2011，49，：	1
12	Oral contraceptives and ovarian cancer; an update,1998-2004显示文摘	LaVecchia C	2006	Eur J Cancer Prew2006，15，2：	1
13	Right ventricular function predicts transplant-free survival in idiopathic dilated cardiomyopathy 显示文摘	LaVecchia L Varotto L Zanolla L	2006	J Cardiovasc Med (Hagerstown)2006，7，9：	1
14	Study of the reducibility of copper in CuO-ZnO catalysts by temperature-programmed reduction显示文摘	FIERRO G LO JACONO M INVERSI M PORTA P CIOCI F LAVECCHIA R	1996	Appl Catal A1996，137，2：	1
15	Risk indicators of organic diseases inuninvestigated dyspepsia: a one - week survey in 246 Italian endoscopyunits 显示文摘	Stanghellini V Anti M Porro GB Corinaldesi R Gasbarrini G Giacosa A Fiocca R LaVecchia C Maconi G Negri E	1999	Eur J Gas- troenterol Hepatol1999，11，：	1
16	Kinetic study of enzymatic urea hydrolysis in the pH range 4-9显示文摘	Fidaleo M Lavecchia R	2003	Chemical and Biochemical Engineering Quarterly2003，17，4：	1
17	The epidemiolo- gy of endometrial carcinoma 显示文摘	Parazzini F Lavecchia C Bocciolone L	2001	J Assoc Physicians India2001，49，3：	1
18	Microbial 16S gene-based composition of a sorghum cropped rhizosphere soil under different fertilization managements显示文摘	Lavecchia A Curci M Jangid K	2015	Biol Fertil Soils2015，51，：	1
19	Improved lycopene extraction from tomato peels using cell-wall degrading enzymes显示文摘	LAVECCHIA R ZUORRO A	2008	Eur Food Res Technol2008，228，1：	1
20	Solubility en- hancement and antibacterial activity of chloramphenicol in-cluded in modified β-cyelodextrins 显示文摘	ZUORRO A FIDALEO M LAVECCHIA R	2010	B Kor Chem Soc2010，31，11：	1

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