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101篇 您的检索式：作者名="Lau JS"

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	题名	作者	年代	出处	被引量
1	Avian influenza virus directly infects human natural killer cells and inhibits cell activity显示文摘Natural killer(NK) cell is a key component of innate immunity and plays an important role in host defense against virus infection by directly destroying infected cells. Influenza is a respiratory disease transmitted in the early phase of virus infection. Evasion of host innate immunity including NK cells is critical for the virus to expand and establish a successful acute infection. Previously,we showed that human influenza H1N1 virus infects NK cells and induces cell apoptosis, as well as inhibits NK cell activity. In this study, we further demonstrated that avian influenza virus also directly targeted NK cells as an immunoevasion strategy. The avian virus infected human NK cells and induced cell apoptosis. In addition, avian influenza virion and HA protein inhibited NK cell cytotoxicity. This novel strategy has obvious advantages for avian influenza virus, allowing the virus sufficient time to expand and subsequent spread before the onset of the specific immune response. Our findings provide an important clue for the immunopathogenesis of avian influenza,and also suggest that direct targeting NK cells may be a common strategy used by both human and avian influenza viruses to evade NK cell immunity.	Huawei Mao Yinping Liu Sin Fun Sia JS Malik Peiris Yu-Lung Lau Wenwei Tu	2017	Virologica Sinica2017，32，2：	4
2	Clusterin plays an important role in hepatocellular carcinoma metastasis 显示文摘	Lau SH Sham JS Xie D	2006	Oncogene2006，25，8：	1
3	Cigarette smoke extract suppresses human dendritic cell function leading to preferential induction of Th - 2 priming 显示文摘	Vassallo R Tamada K Lau JS	2005	J Immunol2005，175，4：	1
4	B7-H3: a costimulatory molecule for T cell activation and IFN-gamma production显示文摘	Chapoval AI Ni J Lau JS	2001	Nat Immunol2001，2，3：	1
5	Characterization of HBV integrants in 14 hepatocellular carcinomas:association of truncated X gene and hepatocellular carcinogenesis显示文摘	Wang Y Lau SH Sham JS		Oncogene0，，：	1
6	B7-H3:a costimulatory molecule for T cell activation and IFN-gamma production显示文摘	Chapoval AI Ni J Lau JS	2001	Nat Immunol2001，2，3：	1
7	B7-H3:a costimulatory molecule for T cell activation and IFN-gamma production显示文摘	Chapoval AI Ni J Lau JS	2001	Nat Immunol2001，2，3：	1
8	Percutaneous transvenous mitral commissurotomy versus surgical commissurotomy in the treatment of mitral stenosis显示文摘	Lau KW Ding ZP Hung JS	1997	Clin Cardiol1997，20，2：	1
9	Early changes of auditory brainstem evoked I CsDonse after radiotherapy for nasopharyn- geal carcinoma: a prospective study显示文摘	Lau SK Wei WI Sham JS	1992	Laryngol Otol1992，106，：	1
10	B7-H3 : a costimulatory mole- cule for T cell activation and IFN-gamma production显示文摘	Chapoval AI Ni J Lau JS	2001	Nat Immuno12001，2，3：	1
11	B7-H3 : a costimulatory molecule for T cell activation and IFN-gamma production 显示文摘	Chapoval AI Ni J Lau JS	2001	Nat Immunol2001，2，3：	1
12	Evaluation of the Chinese ver- sion of the disability of the arm,shoulder and hand (DASH-HKP- WH) : cross -cultural adaptation process,internal consistency and reliability study显示文摘	Lee EW Lau JS Chung MM	2004	J Hand Ther2004，17，4：	1
13	B7-H3: a costimulatory molecule for T cell activation and IFN-:/production显示文摘	Chapoval AI Ni J Lau JS	2001	Nat Immunol2001，2，3：	1
14	B7-143 : a costimulatory molecule for T cell activation and IFN-gamma production 显示文摘	Chapoval AI Ni J Lau JS	2001	Nat Immunol2001，2，3：	1
15	B7-H3:a co-stimulatory moleculefor T cell activation and IFN-gamma production 显示文摘	Chapoval Al Ni J Lau JS	2001	Nat Immunol2001，2，3：	1
16	B7-H3:a costimulatory molecule for T cell activation and IFN-γ production显示文摘	Ni J Lau JS	2001	Nat Immunol2001，2，：	1
17	Atrial fibrillation detection and R wave synchronization by Metrix implantable atrial defibrillator: Implication for long term efficacy and safety显示文摘	Tse HF Lau CP Sra JS	1999	Circulation1999，99，：	1
18	B7-H3:a costimulatory molecule for T cell activation and IFN-γ production显示文摘	Ni J Lau JS	2001	Nat Immunol2001，2，：	1
19	B7-H3: a costimulatory molecule for T cell activation and IFN-/ production 显示文摘	Chapoval AI Ni J Lau JS	2001	Nat Immunol2001，2，3：	1
20	Yoga for secondary prevention of coronary heart disease 显示文摘	Lau HL Kwong JS Yeung F	2012	Cochrane Database Syst Rev2012，12，00：	1

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