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| 1 | Interactions between hepatic iron and lipid metabolism with possible relevance to steatohepatitis显示文摘The liver is an important site for iron and lipid metabolism and the main site for the interactions between these two metabolic pathways. Although conflicting results have been obtained, most studies support the hypothesis that iron plays a role in hepatic lipogenesis. Iron is an integral part of some enzymes and transporters involved in lipid metabolism and, as such, may exert a direct effect on hepatic lipid load, intrahepatic metabolic pathways and hepatic lipid secretion. On the other hand, iron in its ferrous form may indirectly affect lipid metabolism through its ability to induce oxidative stress and inflammation, a hypothesis which is currently the focus of much research in the field of nonalcoholic fatty liver disease/non-alcoholic steatohepatitis (NAFLD/NASH). The present review will first discuss how iron might directly interact with the metabolism of hepatic lipids and then consider a new perspective on the way in which iron may have a role in the two hit hypothesis for the progression of NAFLD via ferroportinand the iron regulatory molecule hepcidin. The review concludes that iron has important interactions with lipid metabolism in the liver that can impact on the development of NAFLD/NASH. More defined studies are required to improve our understanding of these effects. | Umbreen Ahmed Patricia S Latham Phillip S Oates | 2012 | World Journal of Gastroenterology2012,18,34: | 20 |
| 2 | 铁路、人口流动与城市化——略论美国西部开发模式显示文摘对于落后区域的开发过程 ,由于在其初期阶段必然存在着市场失灵 ,因此政府所承担的基础设施建设 ,是实现其发展的第一推动力。然后 ,一些必需的物质要素 ,如人口 ,才会逐渐流向该区域 ,从而使区域内的城市得到迅速的增长 ,并以此带动整个地区的城市化进程。这个普遍性的规律对于任何国家而言都是适用的。本文以此为线索 ,考察了美国历史上的西部开发过程 ,并与中国的西部开发进行了比较。 | 王磊 伍新木 Michael Latham | 2001 | 城市规划汇刊2001,,6: | 5 |
| 3 | The Virtual Geoscience Workbench, VGW: Open Source tools for discontinuous systems显示文摘In 1989 work began on merging finite and discrete elements. During 1990 algorithmic solutions for the new combined method were developed, together with a C-based implementation known as the Y code. In 2004 these developments and implementations were published as a textbook. Queen Mary University of London (QMUL) and Imperial College are currently engaged in a research project to make Y codes in both 2D and 3D available in Open Source format and with mainly geoscience problems in mind. The result is a set of Open Source tools for Geoscience (VGW), key components of which are summarised in this paper, together with illustrative range of simulation results. | A. Munjiza J. Xiang X. Garcia J.P. Latham G.G. Schiava D'Albano N.W.M. John | 2010 | Particuology2010,8,2: | 4 |
| 4 | Latham法和牙龈——骨膜成形术治疗婴儿唇腭裂的初期评价显示文摘简介了 Latham 法和牙龈-骨膜成型术对唇腭裂婴儿的治疗及意义。观察测定了接受该治疗的44例唇腭裂患儿的咬合关系和牙槽裂区新骨形成的状况。结果发现:44例唇腭裂中,15例前牙反(牙合)。27例咬合片中有63%在齿槽裂区有不同程度的新骨生长。对该结果作了初期的评价,并提出了一些改进意见。 | 徐慧芬 Dr.Ralph Latham Dr.Ralph Millard | 1991 | 华西口腔医学杂志1991,9,4: | 2 |
| 5 | Immunohistochemical detection with quantum dots 显示文摘 | Akhtar RS Latham CB Siniscalco D | 2007 | Methods Mol Biol2007,374,: | 1 |
| 6 | Global malnutrition显示文摘 | Stephenson LS Latham MC Ottesen EA | 2000 | Parasitology2000,121,1: | 1 |
| 7 | Formation of wild-type and chimeric influenza virus-like particles following simultaneous expression of only four structural proteins 显示文摘 | Latham T Galarza J M | 2001 | Virology2001,75,13: | 1 |
| 8 | Work motivation theory and research at the dawn of the twenty-first century显示文摘 | Latham G P Pinder C C | 2005 | Annual Review of Psychology2005,,48: | 1 |
| 9 | Optimal Gabor filters for textile flaw detection 显示文摘 | Bodnarova A Bennamoun M Latham S | 2002 | Pattern Recognition2002,35,12: | 1 |
| 10 | Ductility and the Workability of Metals显示文摘 | Cockcroft M G Latham D J | 1968 | Journal of The Institute of Metals1968,96,: | 1 |
| 11 | The association of diabetes and glucose control with surgical-site infections among cardiothoracic surgery patients显示文摘 | Latham R Lancaster AD Covington JF | 2001 | Infect Confrol Hosp Epidemiol2001,22,: | 1 |
| 12 | Self-regulation through goal setting显示文摘 | Latham GP Locke EA | 1991 | Organizational Behavior and Human Decision Processes1991,50,2: | 1 |
| 13 | Needless complexity in the identification of industrial complexes显示文摘 | LATHAM W R | 1976 | Journal of Regional Science1976,16,1: | 1 |
| 14 | The corporate monitoring Finn显示文摘 | M | 1999 | Corporate Governance-An International Review1999,,1: | 1 |
| 15 | Induction of plant cell division by beet curly top virus gene C4 显示文摘 | Latham J R Saunders K Pinner M S | 1997 | The Plant Journal1997,11,: | 1 |
| 16 | The effects of distal learning, outcome, and proximal goals on a moderately complex task显示文摘 | Seijts G H and Latham G P | 2001 | Journal of Organizational Behavior2001,22,3: | 1 |
| 17 | The signaltonoise ratio for speech intelligibility-an auditorium acoustics design index显示文摘 | LATHAM H G | 1979 | Appl Acoust1979,18,: | 1 |
| 18 | Who uses contrast sensitivity in optometric practice显示文摘 | LATHAM K | 1998 | Ophthal Physiol Opt1998,18,1: | 1 |
| 19 | Paradoxical roles of IFN gamma in models of Th1-mediated autoimmunity显示文摘 | Rosloniec EF Latham K Guedez YB | 2002 | Arthritis Res2002,4,6: | 1 |
| 20 | The intemet will drive corporate monitoring显示文摘 | M | 2000 | Corporate Governance International2000,,6: | 1 |