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10篇 您的检索式：作者名="Larusso N"

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		题名	作者	年代	出处	被引量
	1	Aquaporins in the hepatobiliary system显示文摘	Masyuk AI LaRusso N	2006	Hepatology2006，43，251：	1
	2	MicroRNAs in cholangiociliopathies显示文摘	Masyuk T Masyuk A LaRusso N	2009	Cell Cycle2009，8，9：	1
	3	The value of serum CA 19-9 in predicting cholangiocarcinomas in patients with primary sclerosing cholangitis显示文摘	Levy C Lymp J Angulo P Gores G J Larusso N Lindor K D	2005	Dig Dis Sci2005，50，：	1
	4	Cholangiocyte primary cilia in liver health and disease 显示文摘	Masyuk A I Masyuk T V LaRusso N F	2008	Developmental Dynamics2008，237，8：	1
	5	Biliary tract cancers显示文摘	De Groen P C Gores G J LaRusso N F	1999	N Engl J Med1999，341，：	1
	6	The utility of CA 19-9 in the diagnoses ofcholangiocarcinoma in patients without primary scleros-ing cholangitis显示文摘	Patel A H Harnois D M Klee G G LaRusso N F Gores G J	2000	Am J Gastroenterol >2000，95，：	1
	7	Nitric oxide in gastrointestinal epi- thelial cell earcinogenesisdinking inflammation to oncogenesis显示文摘	Jaiswal M Larusso N F Gores G J	2001	Am J Physiol Gastrointest Liver Physiol2001，281，3：	1
	8	Aquaporins in the hepatobiliary system显示文摘	Masyuk A I LaRusso N F	2006	Hepatology2006，43，2：	1
	9	Biliary tract cancers显示文摘	De Groen P Gores G LaRusso N	1999	NEJM1999，341，：	1
	10	Cloning and expression of SLC10A4,a putative organic anion transport protein显示文摘AIM: To determine if novel bile acid transporters may be expressed in human tissues. METHODS: SLC10A1 (NTCP) was used as a probe to search the NCBI database for homology to previously uncharacterized ESTs. The homology search identified an EST (termed SLC10A4) that shares sequence identity with SLC10A1 and SLC10A2 (ASBT). We performed Northern blot analysis and RT-PCR to determine the tissue distribution of SLC10A4. SLC10A4 was cloned in frame with an epitope tag and overexpressed in CHO cells to determine cellular localization and functional analysis of bile acid uptake. RESULTS: Northern analysis revealed that SLC10A4 mRNA is ubiquitously expressed in human tissues with the highest levels of mRNA expression in brain, placenta, and liver. In SLC10A4-transfected CHO cells, immunoblotting analysis and immunofluorescence staining demonstrated a 49-kDa protein that is expressed at the plasma membrane and intracellular compartments. Functional analysis of SLC10A4 showed no significant taurocholate uptake in the presence of sodium when compared to untransfected CHO cells. CONCLUSION: To date, we have shown that this protein has no capacity to transport taurocholate relative to SLC10A1; however, given its ubiquitous tissue distribution, it may play a more active role in transporting other endogenous organic anions.	Patrick L Splinter Konstantinos N Lazaridis Paul A Dawson Nicholas F LaRusso	2006	World Journal of Gastroenterology2006，12，42：	0

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