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1篇 您的检索式：作者名="Larry L.Bellinger"

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		题名	作者	年代	出处	被引量
	1	Effect of Pregnancy on TMJ Nociception in Rats显示文摘Objective:Does TMJ nociception,as measured by a behavioral assay,differ during pregnancy,potentially due to the effect of sex steroids?Methods:Thirty-two Sprague Dawley rats were randomly allocated to either mid-(E11)or late-(E17)pregnancy groups.The animals within each group were further allocated to a saline or CFA treatment.At E11 or E17,the animals were injected bilaterally into TMJ with either saline(15μL)or 1μg/μL CFA(15μL).Nociception was measured with a feeding assay(pellet recording)and analyzed by comparing intra-meal rates using a distance-based permutation method.Results:CFA injection resulted in the animals eating longer in both the mid-pregnant and late-pregnant groups.Plasma estradiol was higher in the late-pregnant group versus the mid-pregnant group.Importantly,the CFA injected late-pregnant group ate for a shorter amount of time(i.e.,shorter meal rate)than the CFA injected rats at mid-pregnancy.Conclusion:The reduced nociceptive response(shorter meal rate)in the CFA injected late-pregnant group may be due to greater estradiol versus the CFA injected mid-pregnancy rats.Thus,one potential reason why women report fewer TMJ symptoms during pregnancy is the higher level of circulating estradiol.	Mikhail Umorin Larry L.Bellinger Phillip R.Kramer	2018	口腔医学研究2018，34，3：	0

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