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| 1 | Functionalization of Single- and Multi-Walled Carbon Nanotubes with Cationic Amphiphiles for Plasmid DNA Complexation and Transfection显示文摘The possibility of delivering DNA effi ciently to cells represents a crucial issue for the treatment of both genetic and acquired diseases.However,even although the effi ciency of non-viral transfection systems has improved in the last decade,none have yet proven to be suffi ciently effective in vivo.We report herein our results on the functionalization of single-walled carbon nanotubes(SWNT)and multi-walled carbon nanotubes(MWNT)by two cationic amphiphiles(lipid RPR120535 and pyrenyl polyamine),their use for the complexation of plasmid DNA,and their efficiency in transfecting cells in vitro.The experiments have shown that the efficiency of transfection is higher when using SWNT instead of MWNT,and that transfection effi ciency is similar or slightly higher when using nanoplexes(SWNT/lipid RPR120535/DNA)instead of lipoplexes(lipid RPR120535/DNA)and several orders of magnitude higher than that of naked DNA.This study therefore shows both that the transfection is better when using SWNTs and that it is dependent on the nature of the amphiphilic molecules adsorbed on the nanotubes. | Cyrille Richard Nathalie Mignet Céline Largeau Virginie Escriou Michel Bessodes Daniel Scherman | 2009 | Nano Research2009，2，8： | 3 |
| 2 | Origin of variations in organic mater abundance and composition in a lithologically homogeneous maar-type oil shale deposit显示文摘 | Derenne S Largeau C Brukner W A | 2000 | Organic Geochemisty2000，31，9： | 1 |
| 3 | A geochemical investigation of carboxylic acids released via sepuential treatments of two surficial sediments from the Changjing delta and East China Sea 显示文摘 | ZEGOUAGH Y DRERENNE S LARGEAU C | 2000 | Organic Geochemistry2000，31，： | 1 |
| 4 | Origin of variations in organic mater abundance and composition in a lithologically homogeneous maar-type oil shale deposit显示文摘 | Derenne S Largeau C Brukner W A | 2000 | Organic Geochemistry2000，31，： | 1 |
| 5 | A review of macromolecular organ- ic compounds that comprise living organisms and their role in kerogen, coal, and petroleum formation 显示文摘 | de Leeuw J W Largeau C | 1993 | Organic geo chemistry: principles and applications1993，，： | 1 |
| 6 | Studies on batch and continuous cultures of Botryococcus braunii hydrocarbon production in relation to physiological state,cell ultrastructure,and phosphate nutrition显示文摘 | Casadevall E Dif D Largeau C | 1985 | Biotechnol Bioeng1985，27，3： | 1 |
| 7 | Immobilization of Botryococcus braunii in alginate: influence on chlorophyll content, photosynthetic activity and degeneration during batch cultures显示文摘 | Bailliez C Largeau C Berkaloff C | 1986 | Appled Microbiological Biotechnology1986，23，5： | 1 |
| 8 | Occurrence and origin of 'ultralarninar' structures in 'armorphous' kerogen of various source rocks and oil shale显示文摘 | Largeau C Dercnne S Casadevall E | 1990 | Organic Geochemistry1990，16，46： | 1 |
| 9 | A reappraisal of kerogen formation 显示文摘 | Tegelaar E W Derenne S Largeau C | 1989 | Geochimica et Cosmochimica Acta1989，531，： | 1 |
| 10 | Botryococcus braunii: a rich source for hydrocarbons and related ether lipids 显示文摘 | Metzger P Largeau C | 2005 | Applied Microbiology and Biotechnology2005，66，5： | 1 |
| 11 | Kerogen origin, evolution and structure显示文摘 | VANDENBROUCKE M LARGEAU C | 2007 | Org Geochem2007，38，： | 1 |
| 12 | Immobilization of Botryococcus Braunnii in Alginate:Influence on Chlorophyll Content,Photosynthetic Activity and Degeneration during Batch Cultures显示文摘 | Bailliez C Largeau C Berkaloff C | 1986 | Appl Microbiol Biotechnol1986，23，5： | 1 |
| 13 | Separation and Characterisation of the C15-Aromatic Fraction of Safaniya Crude Oil显示文摘 | A1 Darouich T Bohar F Largeau C | 2005 | Oil Gas Sei Technol2005，60，4： | 1 |
| 14 | Origin of variations in organic matter abundance and composition in a litholo-gically homogeneous maar-type oil shale deposit显示文摘 | Derenne S Largeau C Brukner-Wein A | 2000 | Organic Geochemistry2000，31，9： | 1 |
| 15 | Sites of accumulation and composition of hydrocarbons in Botryococcus braunii 显示文摘 | Largeau C Casadevall E Berkaloff C | 1980 | Phytochemistry1980，19，6： | 1 |
| 16 | A review of some important families of refractory macromolecules: composition, origin, and fate in soils and sediments显示文摘 | DERENNE S LARGEAU C | 2001 | Soil Science2001，166，： | 1 |
| 17 | Immobilization of boreyococcus braunii in lginate: influence of chlorophll content, photosynthetic activety显示文摘 | Baillies C Largeau C Cberkaloff Casadevall E | 1986 | Appl Microbiol1986，23，： | 1 |
| 18 | Kerogen origin,evolution andstructure显示文摘 | Vandenbroucke M Largeau C | 2007 | Organic Geochemistry2007，38，5： | 1 |
| 19 | Amphiphilic polyether branched molecules to increase the circulalion time of cationic particles 显示文摘 | GAR1NOT M MIGNET N LARGEAU C | 2007 | Bioorg Med Chem2007，15，9： | 1 |
| 20 | A high molecular weight complex lipid,aliphatic polyaldehyde tetraterpenediol polyacetal from Botryococcus braunii (L race) 显示文摘 | BERTHEAS O METZGER P LARGEAU C | 1999 | Phytochemistry1999，50，1： | 1 |
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