2篇
您的检索式：作者名="Lanting Zhao"
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| 1 | Optimization design of multi-gathering mode for the surface system in coalbed methane field显示文摘As a potential resource for emerging clean energy with abundant reserves,coalbed methane(CBM)has risen rapidly in recent years,and the construction of rational and economical CBM gathering system plays a vital role in the development of the oil and gas industry.At present,there is no literature that considers the optimization of the multi-gathering mode of coalbed methane pipe network system.Due to the complexity and high investment,this paper establishes a unified mixed-integer nonlinear programming model to determine the gathering modes(including liquified natural gas,compressed natural gas,and gas gathering station)of gathering system to reduce the cost of coalbed methane collection and export.The objective function is the maximization of total profit during the period of the whole project,and such constraints,like network structure,facility number,location,node flow balance,capacity and variable value,are taken into consideration.The solution strategy and heuristic algorithm is proposed and verified by the field data from Shanxi province(China).The results show that the model can solve the problem for optimization design of the surface system in complicated CBM fields. | Jun Zhou Tiantian Fu Kunyi Wu Yunxiang Zhao Lanting Feng | 2023 | Petroleum2023，9，2： | 0 |
| 2 | Quantitative determination of metaxalone in human plasma by LC-MS and its application in a pharmacokinetic study显示文摘A simple and rapid method using liquid chromatography–mass spectrometry(LC-MS) for the determination of metaxalone in human plasma has been developed and validated.Letrozole was used as the internal standard(IS). The plasma samples were simply treated with acetonitrile which allowed the precipitation of plasma proteins. The chromatographic separation was achieved on a Sapphire C18(2.1 mm × 150 mm, 5 μm, Newark, USA)column using the mobile phase(5 mM ammonium acetate containing 0.01% formic acid:acetonitrile(45:55, v/v)) at a flow rate of 0.3 ml/min. The selected ion monitoring(SIM) in the positive mode was used for the determination of [M + H]+m/z 222.1 and 286.1 for metaxalone and letrozole, respectively. The standard curve obtained was linear(r2≥ 0.99)over the concentration range of 30.24-5040 ng/ml. Meanwhile, no interfering peaks or matrix effect was observed. The method established was simple and successfully applied to a pharmacokinetic study of metaxalone in healthy Chinese volunteers after a single oral dose administration of 800 mg metaxalone. The main pharmacokinetic parameters of metaxalone were as follow: Cmax,(1664 ± 1208) ng/ml and(2063 ± 907) ng/ml;AUC0-36,(13925 ± 6590) ng/ml h and(18620 ± 5717) ng/ml h;t1/2,(13.6 ± 7.7) h and(20.3 ± 7.7) h for the reference and test tablets, respectively. These pharmacokinetic parameters of metaxalone in healthy Chinese volunteers were reported for the first time. | Lanting Zhao Qian Li Chang Shu Keli Wang Li Ding | 2016 | Asian Journal of Pharmaceutical Sciences2016，11，5： | 0 |
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