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| 1 | Chronic hepatitis B infection in pregnancy显示文摘There are no standard guidelines to follow when a patient with chronic hepatitis B infection becomes pregnant or desires pregnancy. Topics to consider include which patients to treat, when to start treatment, what treatment to use and when to stop treatment. Without any prophylaxis or antiviral therapy, a hepatitis B surface antigen and E antigen positive mother has up to a 90% likelihood of vertical transmission of hepatitis B virus(HBV) to child. Standard of care in the United States to prevent perinatal transmission consists of administration of hepatitis B immune globulin and HBV vaccination to the infant. The two strongest risk factors of mother to child transmission(MTCT) of HBV infection despite immunoprophylaxis are high maternal HBV viral load and high activity of viral replication. The goal is to prevent transmission of HBV at birth by decreasing viral load and/or decreasing activity of the virus. Although it is still somewhat controversial, most evidence shows that starting antivirals in the third trimester is effective in decreasing MTCT without affecting fetal development. There is a growing body of literature supporting the safety and efficacy of antiviral therapies to reduce MTCT of hepatitis B. There are no formal recommendations regarding which agent to choose. Tenofovir, lamivudine and telbivudine have all been proven efficacious in decreasing viral load at birth without known birth defects, but final decision of which antiviral medication to use will have to be determined by physician and patient. The antivirals may be discontinued immediately if patient is breastfeeding, or within first four weeks if infant is being formula fed. | Jennifer R Lamberth Sheila C Reddy Jen-Jung Pan Kevin J Dasher | 2015 | World Journal of Hepatology2015，7，9： | 32 |
| 2 | Multicomponent Reactions in Fungicide Research: The Discovery of Mandipropamid Clemens显示文摘 | LAMBERTH C JEANGUENAT A CEDREBAUM F | 2008 | Bioorganic & Medicinal Chemistry2008，16，： | 1 |
| 3 | An integrative approach to CTL epitope prediction:a combined algorithm integrating MHC class I binding,TAP transport efficiency,and proteasomal cleavage predictions显示文摘 | LARSEN M V LUNDEGAARD C LAMBERTH K | 2005 | Eur J Immumol2005，35，8： | 1 |
| 4 | An integrative approach to CTL epitope prediction:a combined algorithm integrating MHC class I binding,TAP transport efficiency,and proteasomal cleavage predictions显示文摘 | Larson MV Lundegaard C Lamberth K | 2005 | Eur J Immunol2005，35，8： | 1 |
| 5 | Synthesis of 4-substituted imidazoqui noxalines显示文摘 | Lamberth C | 1999 | J Prakt Chem1999，341，5： | 1 |
| 6 | Synthesis and acaricidal activity of 4-pyrimidinyloxy- and 4- pyrimidinylaminoethylphenyl dioxolanes and oxime e- thers 显示文摘 | Lamberth C Hillesheim E Bassand D | 2000 | Pest Management Science2000，56，1： | 1 |
| 7 | Pyrazole Chemistry in Crop Protection 显示文摘 | Lamberth C | 2007 | Heterocycles2007，71，7： | 1 |
| 8 | PAGET' s disease of the vulva prevalence of associated vulvar ad enocarincma invasive paget' s disease and recurrence after surgical excision 显示文摘 | Fanning J LambertH C Hale TM | 1999 | Am J Obstet Gynecol1999，180，1： | 1 |
| 9 | Large-Scale validation of methods for cytotoxic T-lymphocyte epitope prediction显示文摘 | Larsen M V Lundegaard C Lamberth K | 2007 | BMC Bioinformatics2007，8，1： | 1 |
| 10 | An integralive approach to CTL epitope prediction: a combined algorithm integrating MHC class I binding, TAP transport efficiency, and proteasomal cleavage predictions 显示文摘 | Larsen MV Lundegaard C Lamberth K | 2005 | Eur J Immumol2005，35，8： | 1 |
| 11 | An integrative approach to CTL epitope prediction: a combined algorithm integrating MHC class I binding, TAP transport efficiency, and proteasomal cleavage predictions显示文摘 | Larsen M V Lundegaard C Lamberth K | 2005 | Eur J Immunol2005，35，8： | 1 |
| 12 | Synthesis of substituted man- delic acid derivatives via enantioseleetive hydrogenation:Homoge- neous versus heterogeneous catalysis显示文摘 | CEDERBAUM F LAMBERTH C | 2004 | Advanced Synthesis 8 Catalysis2004，346，7： | 1 |
| 13 | An inte grative approach to CTL epitope prediction: a combined algorithm integrating MHC class I binding, TAP transport efficiency, and proteasomal cleavage predictions 显示文摘 | LARSEN MV LUNDEGAARD C LAMBERTH K et ol | 2005 | Eur J Immu?mol2005，35，8： | 1 |
| 14 | One-Pot, Mix-and-Read Peptide-MHC Tetramers显示文摘 | Leisner C Loeth N Lamberth K | 2008 | PLoS ONE2008，3，2： | 1 |
| 15 | Amino acid chemistry in crop protection 显示文摘 | Lamberth C | 2010 | Tetrahedron2010，66，36： | 1 |
| 16 | Concise Approach to 1- Thiahydantocidin 显示文摘 | LAMBERTH C BLARER S | 1996 | Synthetic Communications1996，26，： | 1 |
| 17 | An integrative ap- proach to CTL epitope prediction: a combined algorithm integrating MHC class Ⅰ binding, TAP transport efficiency, and proteasornal cleav- age predictions 显示文摘 | Larsen MV Lundegaard C Lamberth K | 2005 | Eur J Immumol2005，35，8： | 1 |
| 18 | Mulficomponent reactions in fungicide research: the discovery of rnandipropamid显示文摘 | LAMBERTH C JEANGUENAT A CEDREBAUM F | 2008 | Bioorg &Med Chem2008，16，3： | 1 |
| 19 | Pyrimidine chemistry in crop protection显示文摘 | LAMBERTH C | 2006 | Heteroeyeles2006，68，3： | 1 |
| 20 | An integrative approach to CTL epitope prediction:A combined algorithm integrating MHC class Ⅰ binding,TAP transport efficiency,and proteasomal cleavage predictions显示文摘 | Larsen MV Lundegaard C Lamberth K | 2005 | Eur J Immunol2005，35，8： | 1 |
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