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1Histologic characteristics of gastric polyps in Korea: Emphasis on discrepancy between endoscopic forceps biopsy and endoscopic mucosal resection specimen显示文摘瞄准:在朝鲜人口调查胃的息肉的组织学的特征。方法:我们与胃的息肉考察了内视镜的相片和病人的医药记录通过 2003 年 2 月从 1996 年 4 月经历了内视镜的粘膜切除术。结果:从 74 个病人的 85 胃的息肉的一个总数被考察。Male-to-female 比率是 1:1.96。吝啬的年龄是 59.9 +/- 10.8 年。多重息肉在 10.8% 被观察。胃的息肉最经常发生在窦(58.8%) 。resected 标本上的病理学的结果如下:管状腺瘤 45.9% ,增生的息肉 31.8% ,煽动性的息肉 9.4% ,错构瘤 3.5% ,底的腺息肉 2.4% , tubulovillous 腺瘤 2.4% ,腺癌 2.4% ,发育异常 1.1% ,并且粘膜 pseudolipomatosis 1.1% 。在 resected 标本的内视镜的活体检视和病理之间的差异率是 27.1% 。在息肉和词语索引率的尺寸之间没有关系。结论:在在内视镜的钳活体检视和 resected 标本之间的 histologic 调查结果有可观的差异。全部息肉的组织学的评论的途径应该被执行,特别当一个腺瘤被怀疑时。Won Jae Yoon Dong Ho Lee Yong Jin Jung Ji Bong Jeong Ji Won Kim Byeong Gwan Kim Kook Lae Lee Kwang Hyuck Lee Young Soo Park Jin-Hyeok Hwang Jin-Wook Kim Nayoung Kim Jun Kyu Lee Hyun Chae Jung Yong Bum Yoon In Sung Song 2006World Journal of Gastroenterology2006,12,25:19
2Role of ascites adenosine deaminase in differentiating between tuberculous peritonitis and peritoneal carcinomatosis显示文摘AIM: To investigate the usefulness of tumor markers and adenosine deaminase in differentiating between tuberculous peritonitis (TBP) and peritoneal carcinoma- tosis (PC). METHODS: A retrospective analysis of data was performed on consecutive patients who underwent perito-neoscopic and abdominal computed tomography (CT) evaluations. Among 75 patients at the Seoul National University Hospital from January 2000 to June 2010 who underwent both tests, 27 patients (36.0%) and 25 patients (33.3%) were diagnosed with TBP and PC, respectively. Diagnosis was confirmed by peritoneoscopic biopsy. RESULTS: Serum c-reactive protein (7.88 ± 6.62 mg/ dL vs 3.12 ± 2.69 mg/dL, P = 0.01), ascites adenosine deaminase (66.76 ± 32.09 IU/L vs 13.89 ± 8.95 IU/L, P < 0.01), ascites lymphocyte proportion (67.77 ± 23.41% vs 48.36 ± 18.78%, P < 0.01), and serumascites albumin gradient (0.72 ± 0.49 g/dL vs 1.05 ± 0.50 g/dL, P = 0.03) were significantly different between the two groups. Among tumor markers, serum and ascites carcinoembryonic antigen, serum carbohydrate antigen 19-9 showed significant difference between two groups. Abdominal CT examinations showed that smooth involvement of the parietal peritoneum was more common in the TBP group (77.8% vs 40.7%) whereas nodular involvement was more common in the PC group (14.8% vs 40.7%, P = 0.04). From receiver operating characteristic (ROC) curves ascites adenosines deaminase (ADA) showed better discriminative capability than tumor markers. An ADA cut-off level of 21 IU/L was found to yield the best results of differential diagnosis; sensitivity, specificity, positive predictive value, and negative predictive value were 92.0%, 85.0%, 88.5% and 89.5%, respectively. CONCLUSION: Besides clinical and radiologic findings, ascitic fluid ADA measurement is helpful in the differential diagnosis of TBP and PC.Seung Joo Kang Ji Won Kim Jee Hyun Baek Se Hyung Kim Byeong Gwan Kim Kook Lae Lee Ji Bong Jeong Yong Jin Jung Joo Sung Kim Hyun Chae Jung In Sung Song 2012World Journal of Gastroenterology2012,18,22:15
3Clinical significance of CT-defined minimal ascites in patients with gastric cancer显示文摘AIM: To study the clinical significance of minimal ascites,which was only defined by the CT and whose nature was not determined preoperatively, in the relationship with the peritoneal carcinomatosis.METHODS: The medical records and the dynamic CT films of 118 patients with gastric cancer were reviewed.Factors associated with peritoneal carcinomatosis were analyzed in 40 patients who had CT-defined ascites of which the nature was surgically confirmed.RESULTS: Only 12.5-25% of the CT-defined minimal ascites, whose volume was estimated to be less than 50 mL, were associated with peritoneal carcinomatosis.When the estimated CT-defined ascitic volume was 50 mL or more, peritoneal carcinomatosis was identified in 75-100%. When CT-defined lymph node enlargements were not found beyond the regional gastric area,perigastricinvasions were not suspected, and the size of tumor was less than 3 cm, peritoneal carcinomatosis seemed significantly less accompanied at the univariate analysis. However, except for the minimal volume of CTdefined ascites in comparison with the mild or more,other factors were not confirmed multivariately.CONCLUSION: In the patients with gastric cancer, CTdefined minimal ascites alone is rarely associated with peritoneal carcinomatosis, if it does not accompany other signs suggestive of malignant seeding. Therefore,consideration of active curative resection should not be hesitated, if CT-defined minimal ascites is the only delusive sign.Dong Kyung Chang Ji Won Kim Byung Kwan Kim Kook Lae Lee Chi Sung Song Joon Koo Han In Sung Song 2005World Journal of Gastroenterology2005,11,42:14
4Long-term outcome in patients with obscure gastrointestinal bleeding after negative capsule endoscopy显示文摘AIM:To investigate long-term outcome in obscure gastrointestinal bleeding(OGIB) after negative capsule endoscopy(CE) and identify risk factors for rebleeding.METHODS:A total of 113 consecutive patients underwent CE for OGIB from May 2003 to June 2010 at Seoul National University Hospital.Ninety-five patients(84.1%) with a subsequent follow-up after CE of at least 6 mo were enrolled in this study.Follow-up data were obtained from the patients' medical records.The CE images were reviewed by two board-certified gastroenterologists and consensus diagnosis was used in all cases.The primary outcome measure was the detection of rebleeding after CE,and factors associated with rebleeding were evaluated using multivariate analysis.RESULTS:Of the 95 enrolled patients(median age 61 years,range 17-85 years),62 patients(65.3%) were male.The median duration of follow-up was 23.7 mo(range 6.0-89.4 mo).Seventy-three patients(76.8%) underwent CE for obscure-overt bleeding.Complete examination of the small bowel was achieved in 77 cases(81.1%).Significant lesions were found in 38 patients(40.0%).The overall rebleeding rate was 28.4%.The rebleeding rate was higher in patients with positive CE(36.8%) than in those with negative CE(22.8%).However,there was no significant difference in cumulative rebleeding rates between the two groups(log rank test;P = 0.205).Anticoagulation after CE examination was an independent risk factor for rebleeding(hazard ratio,5.019;95%CI,1.560-16.145;P = 0.007),regardless of CE results.CONCLUSION:Patients with OGIB and negative CE have a potential risk of rebleeding.Therefore,close observation is required and alternative modalities should be considered in suspicious cases.Seong-Joon Koh Jong Pil Im Ji Won Kim Byeong Gwan Kim Kook Lae Lee Sang Gyun Kim Joo Sung Kim Hyun Chae Jung 2013World Journal of Gastroenterology2013,19,10:12
5最新标签本体:标签和民俗分类法语义模型显示文摘当前,人们越来越关注协作化标签系统中标签数据的表示和共享。传统的标签(指随意标注的、没有与结构化本体相关联的标签)由于语言和语法的差异以及录入错误等,不适于做协作化处理。而且标签反映的是用户个人的观点,也不对同义词、词形变化或者其他对照映射关系做规范处理。因此笔者认为,标签的常规处理方法对语义协作的贡献非常有限,即便是有,要让计算机实现自动共享也是极其困难的。在语义层面上讨论数种协作标签标注的方法,提出一个标签协作标注和设计民俗分类法的概念模型,同时比较已有的标签本体,提出一个评价标准,并参照该标准讨论这些标签本体的优缺点。Hak Lae Kim SimonScerri JohnG.Breslin StefanDecker HongGeeKim 丁鹏宇(译) 黄田青 刘炜(校) 2009现代图书情报技术2009,,3:11
6Proton pump inhibitors as a risk factor for recurrence of Clostridium-difficile-associated diarrhea显示文摘AIM:To investigate the risk factors for Clostridiumdifficile-associated diarrhea(CDAD)recurrence,and its relationship with proton pump inhibitors(PPIs). METHODS:Retrospective data of 125 consecutive hospitalized patients diagnosed with CDAD between January 2006 and December 2007 were collected by medical chart review.Collected data included patient characteristics at baseline,underlying medical disease, antibiotic history before receiving a diagnosis of CDAD, duration of hospital stay,severity of CDAD,concurrenttreatment with PPIs,laboratory parameters,response to CDAD therapy,and recurrence of disease within 90 d of successful treatment.Various clinical and laboratory parameters were compared in patients in whom CDAD did or did not recur. RESULTS:Of the 125 patients(mean age,67.6± 13.9 years)that developed CDAD,98(78.4%)did not experience recurrence(non-recurrent group)and 27 (21.6%)experienced one or more recurrences(recurrent group).Prior to the development of CDAD,96% of the 125 patients were prescribed antibiotics,and 56(44.8%)of the patients received PPIs.Age older than 65 years(P=0.021),feeding via nasogastric tube(NGT)(P=0.045),low serum albumin level(P =0.025),and concurrent use of PPIs(P=0.014) were found to be risk factors for CDAD recurrence by univariate analysis.However,sex,length of hospital stay,duration and type of antibiotics used,severity of disease,leukocyte count and C-reactive protein(CRP) were not associated with risk of CDAD recurrence.On multivariate analysis,the important risk factors were advanced age(>65 years,adjusted OR:1.32,95% CI:1.12-3.87,P=0.031),low serum albumin level(< 2.5 g/dL,adjusted OR:1.85,95%CI:1.35-4.91,P= 0.028),and concurrent use of PPIs(adjusted OR:3.48, 95%CI:1.64-7.69,P=0.016). CONCLUSION:Advanced age,serum albumin level< 2.5 g/dL,and concomitant use of PPIs were found to be significant risk factors for CDAD recurrence.Ji Won Kim Kook Lae Lee Ji Bong Jeong Byeong Gwan Kim Sue Shin Joo Sung Kim Hyun Chae Jung In Sung Song 2010World Journal of Gastroenterology2010,16,28:10
7Application of Cellulose Nanofibril as a Wet-end Additive in Papermaking:A Brief Review显示文摘Recently,cellulose nanofibril(CNF)has emerged as a promising,sustainable reinforcement with outstanding potential in material science.Owing to the properties of CNF,it has been explored in food,cosmetic,and pharmaceutical applications,as well as in industrial applications such as paints,drill muds,packaging,and papermaking.The application of CNF in papermaking is expected to be implemented in the near future to broaden the commercial market of cellulose.Numerous studies and patents have reported on the manufacturing,properties,and applications of nanocellulose.This present paper focuses on the recent progresses in the application of CNF as a wet-end additive in papermaking.Guihua Yang Guangrui Ma Ming He Xinxiang Ji Hye Jung Youn Hak Lae Lee Jiachuan Chen 2020Paper And Biomaterials2020,5,2:9
8Discrepancies between primary physician practice and treatment guidelines for Helicobacterpylori infection in Korea显示文摘瞄准:在 Helicobacter pylori 的诊断和治疗评估主要照顾医生的态度(H。pylori ) 感染。方法:在汉城大城市的区域的主要照顾医生从 1 月回答了自我管理的问询表到 2003 年 3 月。结果:108 位医生对问询表作出回应。为严峻的 H 的最经常的原因。pylori 感染是胃的并且十二指肠溃疡(93.5% 和 88.9% ,分别地) 。为有 H 的病人。pylori 积极消化不良, 28.7% 医生总是试着根除蠕虫并且 34.4% 有选择地对待。主要照顾医生的一个大比例(28.7%) 对待 H。一个病人的请求基础上的 pylori。仅仅, 9.3% 主要照顾医生总是进行了在对待 H 以后测试的后续。pylori 感染。什么时候 H。pylori 没被第一治疗清除, 40.7% 医生再使用一样的政体, 16.7% 改变了到另一三倍的政体并且 25% 到四倍的政体。结论:指南的发行几乎独自没在实践上有很少影响,这很好被记录了。在在连续医药教育形式的主要照顾医生和胃的肠学之间的通讯被要求。Byeong Gwan Kim Ji Won Kim Ji Bong Jeong Young Jin Jung Kook Lae Lee Young Soo Park Jin Huk Hwang Jin Uk Kim Na Young Kim Dong Ho Lee Hyun Chae Jung In Sung Song 2006World Journal of Gastroenterology2006,12,1:8
9Clinical and endoscopic characteristics of drug-induced esophagitis显示文摘AIM: To investigate clinical, endoscopic and pathological characteristics of drug-induced esophagitis.METHODS: Data for patients diagnosed with drug-induced esophagitis from April 2002 to May 2013 was reviewed. Patients diagnosed with malignancy, viral or fungal esophagitis were excluded. Clinical, endoscopic and pathological characteristics of patients diagnosed with drug-induced esophagitis were analyzed.RESULTS: Seventy-eight patients were diagnosed with drug-induced esophagitis. Their mean age was 43.9 ± 18.9 years and 35.9% were male. Common symptoms were chest pain(71.8%), odynophagia(38.5%) and dysphagia(29.5%). The endoscopic location was in the middle third of esophagus in 78.2%. Endoscopic findings were ulcer(82.1%), erosion(17.9%), ulcer with bleeding(24.4%), coating with drug material(5.1%), impacted pill fragments(3.8%) and stricture(2.6%). Kissing ulcers were observed in 43.6%. The main causative agents were antibiotics and non-steroidal antiinflammatory drugs. All the patients were treated with proton pump inhibitors(PPIs) or sucralfate, and the causative drugs were discontinued. Nineteen patients with drug-induced esophagitis were followed up with endoscopy and revealed normal findings, scars or healing ulcers.CONCLUSION: Drug-induced esophagitis mainly presents as chest pain, odynophagia and dysphagia, and may be successfully treated with PPIs and discontinuation of the causative drug. Kissing ulcers were observed in 43.6%.Su Hwan Kim Ji Bong Jeong Ji Won Kim Seong-Joon Koh Byeong Gwan Kim Kook Lae Lee Mee Soo Chang Jong Pil Im Hyoun Woo Kang Cheol Min Shin 2014World Journal of Gastroenterology2014,20,31:7
10Restraint stress induces and exacerbates intestinal inflammation in interleukin-10 deficient mice显示文摘AIM:To investigate the effects of restraint stress on chronic colitis in interleukin(IL)-10 deficient(IL-10^(-/-))mice.METHODS:The first experiment compared the effect of restraint stress on the development of intestinal inflammation in wild-type and IL-10^(-/-) mice.Both wildtype and IL-10^(-/-) mice were physically restrained in a well-ventilated,50 cm3 conical polypropylene tube for2 h per day for three consecutive days.The second experiment was performed to assess the effect of restraint stress on exacerbation of colitis induced by piroxicam in IL-10^(-/-) mice.The IL-10^(-/-) mice were exposed to restraint stress for 2 h per day for 3consecutive days,and then treated with piroxicam for4 d at a dose of 200 ppm administered in the rodent chow.RESULTS:In the first experiment,none of the wildtype mice with or without restraint stress showed clinical and histopathological abnormality in the gut.However,IL-10^(-/-) mice exposed to restraint stress exhibited histologically significant intestinal inflammation as compared to those without restraint stress.In the second experiment,restraint stress significantly reduced body weight and increased the severity of intestinal inflammation assessed by histopathologic grading in IL-10^(-/-) mice.Colonic IL12p40 mRNA expression was strongly increased in mice exposed to restraint stress.CONCLUSION:This novel animal model could be useful in future study of psychological stress in the pathogenesis of inflammatory bowel disease.Seong-Joon Koh Ji Won Kim Byeong Gwan Kim Kook Lae Lee Joo Sung Kim 2015World Journal of Gastroenterology2015,21,28:3
11Fatty liver is an independent risk factor for gallbladder polyps显示文摘BACKGROUND Gallbladder polyps(GBPs)are known to be associated with obesity and metabolic diseases.However,to date,the relationship between GBPs and abnormal body fat distribution,such as fatty liver,visceral obesity,or sarcopenia,has not yet been established.AIM To evaluate whether GBPs are associated with fatty liver,visceral obesity,or sarcopenia.METHODS We retrospectively reviewed the medical records of subjects who underwent various laboratory tests,body composition measurement with a non-invasive body composition analyzer,and abdominal ultrasonography during health checkups.A total of 1405 subjects with GBPs were compared with 2810 age-and sex-matched controls.RESULTS The mean age of the subjects was 46.8±11.7 years,and 63.8%were male.According to multiple logistic regression analysis,the presence of fatty liver[odds ratio(OR)1.413;95%confidence interval(CI)1.218-1.638;P<0.001]was an independent risk factor for GBP,together with low levels of alanine aminotransferase(OR 0.993;95%CI 0.989-0.996;P<0.001).Additionally,fatty liver showed both independent(OR 1.629;95%CI,1.335-1.988;P<0.001)and dosedependent(moderate to severe fatty liver;OR 2.137;95%CI,1.662-2.749;P<0.001)relationship with large GBPs(≥5 mm).The presence of sarcopenia and high visceral fat area were not significantly associated with GBPs.CONCLUSION Fatty liver was found to be closely associated with GBPs irrespective of sarcopenia and visceral obesity.Dong-Won Ahn Ji Bong Jeong Jinwoo Kang Su Hwan Kim Ji Won Kim Byeong Gwan Kim Kook Lae Lee Sohee Oh Soon Ho Yoon Sang Joon Park Doo Hee Lee 2020World Journal of Gastroenterology2020,26,44:3
12Comparison between uncovered and covered self-expandable metal stent placement in malignant duodenal obstruction显示文摘AIM:To compare the clinical outcomes of uncovered and covered self-expandable metal stent placements in patients with malignant duodenal obstruction.METHODS:A total of 67 patients were retrospectivelyenrolled from January 2003 to June 2013.All patients had symptomatic obstruction characterized by nausea,vomiting,reduced oral intake,and weight loss.The exclusion criteria included asymptomatic duodenal obstruction,perforation or peritonitis,concomitant small bowel obstruction,or duodenal obstruction caused by benign strictures.The technical and clinical success rate,complication rate,and stent patency were compared according to the placement of uncovered(n = 38) or covered(n = 29) stents.RESULTS:The technical and clinical success rates did not differ between the uncovered and covered stent groups(100% vs 96.6% and 89.5% vs 82.8%).There were no differences in the overall complication rates between the uncovered and covered stent groups(31.6% vs 41.4%).However,stent migration occurred more frequently with covered than uncovered stents [20.7%(6/29) vs 0%(0/38),P < 0.05].Moreover,the overall cumulative median duration of stent patency was longer in uncovered than in covered stents [251 d(95%CI:149.8 d-352.2 d) vs 139 d(95%CI:45.5 d-232.5 d),P < 0.05 by log-rank test] The overall cumulative median survival period was not different between the uncovered stent(70 d) and covered stent groups(60 d).CONCLUSION:Uncovered stents may be preferable in malignant duodenal obstruction because of their greater resistance to stent migration and longer stent patency than covered stents.Ji Won Kim Ji Bong Jeong Kook Lae Lee Byeong Gwan Kim Dong Won Ahn Jae Kyung Lee Su Hwan Kim 2015World Journal of Gastroenterology2015,21,5:2
13Effect of gastric acid suppressants and prokinetics on peritoneal dialysis-related peritonitis显示文摘AIM: To investigate the effect of gastric acid suppressants and prokinetics on peritonitis development in peritoneal dialysis(PD) patients.METHODS: This was a single-center, retrospective study. The medical records of 398 PD patients were collected from January 2000 to September 2012 and analyzed to compare patients with at least one episode of peritonitis(peritonitis group, group A) to patients who never had peritonitis(no peritonitis group, group B). All peritonitis episodes were analyzed to compare peritonitis caused by enteric organisms and peritonitis caused by non-enteric organisms.RESULTS: Among the 120 patients who met the inclusion criteria, 61 patients had at least one episode ofperitonitis and 59 patients never experienced peritonitis. Twenty-four of 61 patients(39.3%) in group A and 15 of 59 patients(25.4%) in group B used gastric acid suppressants. Only the use of H2-blocker(H2B) was associated with an increased risk of PD-related peritonitis; the use of proton pump inhibitors, other antacids, and prokinetics was not found to be a significant risk factor for PD-related peritonitis. A total of 81 episodes of peritonitis were divided into enteric peritonitis(EP) or non-enteric peritonitis, depending on the causative organism, and gastric acid suppressants and prokinetics did not increase the risk of EP in PD patients.CONCLUSION: The use of H2B showed a trend for an increased risk of overall PD-related peritonitis, although further studies are required to clarify the effects of drugs on PD-related peritonitis.Ji Eun Kwon Seong-Joon Koh Jaeyoung Chun Ji Won Kim Byeong Gwan Kim Kook Lae Lee Jong Pil Im Joo Sung Kim Hyun Chae Jung 2014World Journal of Gastroenterology2014,20,25:2
14Stress and sleep quality in doctors working on-call shifts are associated with functional gastrointestinal disorders显示文摘AIM To investigate the role of sleep quality and psychosocial problems as predictors of functional gastrointestinal disorders(FGIDs) in doctors that work 24 hour-on-call shifts.METHODS In this cross-sectional observation study, using the Rome Ⅲ Questionnaire and Pittsburgh Sleep Quality Index(PSQI), we analyzed 170 doctors with 24 houron-call shifts. RESULTS Among the participants that had experienced a 24 hour-on-call shift within the last 6 mo, 48(28.2%) had FGIDs. Overall prevalence of irritable bowel syndrome(IBS) and functional dyspepsia(FD) were 16.5% and 17.1%, respectively, with 5.3% exhibiting both. Sleep scores(PSQI)(8.79 ± 2.71 vs 7.30 ± 3.43, P = 0.008), the presence of serious psychosocial alarm(83.3%vs 56.6%, P = 0.004), and the proportion of doctors who experienced over two months of recent on-call work(81.2% vs 68.9%, P = 0.044) were significantly different between individuals with or without FGIDs. Multivariate analysis revealed that presenting serious psychosocial alarm was an independent risk factor for prevalence of FD(OR = 5.47, 95%CI: 1.06-28.15, P = 0.042) and poor sleep quality(PSQI ≥ 6) was a predictor of IBS(OR = 4.17, 95%CI: 1.92-19.02, P = 0.016). CONCLUSION Physicians should recognize the role of sleep impairment and psychological stress in the development of FGIDs and a comprehensive approach should be considered to manage patients with FGIDs.Soo-Kyung Lim Seung Jin Yoo Dae Lim Koo Chae A Park Han Jun Ryu Yong Jin Jung Ji Bong Jeong Byeong Gwan Kim Kook Lae Lee Seong-Joon Koh 2017World Journal of Gastroenterology2017,23,18:2
15The characteristics of compensation on temperature of ultrasonic motor with robot actuator by fuzzy controller显示文摘In - su Hea- Am Park Huyng -lae Back 1996Proceedings of the IEEE International Symposium on Industrial Electronics1996,1,:2
16Surface sizing with cationic starch: its effect on paper quality and the papermaking process显示文摘Hak Lae Lee Jae Young Shin Chang-Heon Koh 2002Tappi Journal2002,1,1:1
17Clusterin expression distinguishes follicular dendritic cell tumors from other dendritic cell neoplasms:report of a novel follicular dendritic cell marker and clinieopathologie data on 12 additional follicular dendritic cell tumors and 6 additional interdigitating dendritic cell tumors显示文摘Grogg KL Lae ME Kurtin PJ 2004Am J Surg Pathol2004,28,8:1
18A proposed diagnosis scheme for people with epileptic seizures and with epilepsy:report of the LAE Task Force on Classification and Terminology显示文摘Engel J Jr International League Against Epilepsy(LAE) 2001Epilepsia2001,42,7:1
19Oxidative stress: relationship with ex- ercise and training显示文摘Finaud J Lae G Filaire E 2006Sports Med2006,36,4:1
20Sense of coherence, well-being, coping and personality factors: further evaluation of the sense of coherence scale显示文摘Pallant JF Lae L 2002Pers Individ Dif2002,33,1:1
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