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| 1 | Effect of intestinal ischemia-reperfusion on expressions of endogenous basic fibroblast growth factor and transforming growth factor β in lung and its relation with lung repair显示文摘AIM To study the changes of endogenoustransforming growth factor β(TGFβ)and basicfibroblast growth factor(bFGF)in lung followingintestinal ischemia and reperfusion injury andtheir effects on lung injury and repair.METHODS Sixty Wistar rats were divided intofive groups,which underwent sham-operation,ischemia(45 minutes),and reperfusion(6,24and 48 hours,respectively)after ischemia(45minutes).Immunohistochemical method wasused to observe the localization and amounts ofboth growth factors.RESULTS Positive signals of both growthfactors could be found in normal lung,mainly inalveolar cells and endothelial cells of vein.Afterischemia and reperfusion insult,expressions ofboth growth factors were increased and theiramounts at 6 hours were larger than those ofnormal control or of 24 and 48 hours after insult.CONCLUSION The endogenous bFGF and TGF βexpression appears to be up-regulated in thelung following intestinal ischemia andreperfusion,suggesting that both growth factorsmay be involved in the process of lung injury andrepair. | Xiao Bing Fu Yin Hui Yang Tong Zhu Sun Xiao Man Gu Li Xian Jiang Xiao Oing Sun Zhi Yong Sheng Research Laboratory,304th Hospital of PLA,Beijing 100037,China | 2000 | World Journal of Gastroenterology2000，6，3： | 21 |
| 2 | Oligomeric Procyanidins Induce Generation of Reactive Oxygen Species and Collapse of Mitochchondrial Membrane Potential in Glioblastoma Cell Lines显示文摘Objective The aim of the present study was to clarify the mechanism underlying glioma cell death upon oligomeric procyanidins (F2) exposure. Methods The cytotoxicity of F2 on U87 (human malignant glioblastoma cell line) and C6 (rat glioma cell line) cancer cells was evaluated, and changes of mitochondrial membrane potential (MMP) and production of reactive oxygen species (ROS) in drug-treated cells were monitored. Moreover, morphological changes associated with F2-induced cells death were examined. Results F2 induced a concentration-dependent increase in ROS production and decrease in MMP. Furthermore, pre-incubation with N-acetylcysteine (NAC) and rotenone (Rt), resulted in partial inhibition of F2-induced ROS generation and marked attenuation of cell death and the cytoplasmic vacuolization induced by F2. In addition, pretreatment with Rt markedly attenuated the MMP loss in F2-treated cells. However, pretreatment with NAC only markedly attenuated the MMP loss in F2-treated C6 cells. Conclusion The increase in ROS level is at least one of mechanisms associated with F2-induced glioma cell death as well as the cytoplasmic vacuolization formation that contribute to the cytotoxicity of F2 in glioma cells. | ZHANG Feng-jiao1, YANG Jing-yu1, MOU Yan-hua1, SUN Bao-shan2, WANG Ji-ming3, WANG Fang1, WU Chun-fu1 1. Department of Pharmacology, Shenyang Pharmaceutical University, Shenyang 110016, China 2. Estaco Vitivinícola Nacional, Instituto National de Investigaco Agrária, Dois Portos 2565-191, Portugal 3. Laboratory of Molecular Immunoregulation, Cancer and Inflammation Program, Center for Cancer Research, National Cancer Institute at Frederick, Frederick Maryland 21702, USA | 2009 | Chinese Herbal Medicines2009，1，1： | 3 |
| 3 | Selenocysteine tRNAs as Central Components of Selenoprotein Biosynthesis in Eukaryotes显示文摘Selenocysteine (Sec) tRNAs serve as carrier molecules for the biosynthesis of Sec from serine and to donate Sec to protein in response to specific UGA codons. In this study, we describe the current status of Sec tRNAs in higher animals and further we exarnine: (i) the Sec tRNA population in Drosophila; (ii) transcription of the Sec tRNA in vivo (in Xenopus oocytes) and in vitro (in Xenopus oocyte extracts); (iii) the effect of selenium on the Sec tRNA population in various rat tissues following replenishment of extremely selenium deficient rats with this element; and (iv) the biosynthesis of the modified bases on Sec tRNA in Xenopus | SANG ICK PARK JIN Mo PARK HAROLD S. CHITTUM EUN SUNG YANG BRADLEY A. CARLSON BYEONG JAE LEE AND DOLPH L. HATFIELD(Laboratory of Experimental Chrcinogenesis, National Cancer Insti tute, National Institutes of Health, Bethesda, MD 20892USA Laboratory o | 1997 | Biomedical and Environmental Sciences1997，10，2： | 2 |
| 4 | Proposed draft revised guideline levels for radionuclides in foods for use in international trade (At step 5 of the procedure ) 显示文摘 | A Joint FAO O/IAEA Division of Nuclear Techniques in Food and Agriculture and FAO/IAEA Agriculture and Biotechnology Laboratory | 2004 | Food and Environmental Protection New sletter2004，6，2： | 1 |
| 5 | Preparation of MCM-41 in Industrial Scale and Its Application in Heavy Oil Processing显示文摘A series of MCM 41 molecular sieves have been prepared on an industrial scale, and the effect of preparation factors such as aging temperature, pH values on the structure and pore distribution of the MCM 41 product have been studied by using X ray diffraction(XRD), thermogravimetric(TG) and electron microscopy(TEM). It is shown that the pH values have a significant effect on the crystallinity of the synthesized product. Under proper conditions, the MCM 41 prepared on an industrial scale has the same performance as the samples prepared on an Lab scale. The prepared MCM 41 was used as a modifier of zeolite Y for fluid catalytic cracking(FCC) of residual oil. It is shown that the addition of the MCM 41 in the zeolite Y catalyst increases the pore size, and surface area of the catalysts, which helps to increase the yield of gasoline and diesel and decrease the production of gaseous product and carbon deposition in the catalyst. The better performance of the MCM 41 modified zeolite Y catalyst is believed to be due to its adjustment on the acidity and increase of the pore size. | Jianwen Da 1,2 , Tiancun Xiao 2, Jianming Su 1, Xingzhong Xu 1 and Malcolm. L. H. Green 2,* 1. Research Institute of Qilu Petrochem. Corp., Zibo 255400, China 2. The Wolfson Catalysis Centre, Inorganic Chemistry Laboratory, University of O | 2002 | Chemical Research in Chinese Universities2002，18，2： | 1 |
| 6 | Magnetic, Geochemical and Mineralogical Charac teristics of Soils in Qiangtang Basin, Tibet, China: Implications for Prospective Oil and Gas Land显示文摘The alteration of iron bearing minerals induced by hydrocarbon microseepage above oil/gas reservoirs has been evaluated using measurements of soil magnetic susceptibility κ , geochemical compositions (gas hydrocarbon and alteration carbonate Δ C ), and composition and concentration of iron bearing minerals. The analyses were performed along two profiles across the Qiangtang basin in Tibet, China: the Nuoermahu Xuehuanhu profile (C) and the Mugari Huochetoushan profile (E). Results show that three strong magnetic anomalies (C 1, E 1 and E 2 anomalies) are related to the distribution of Neogene volcanic rocks on the surface in the Gangmacuo Xiyaergang uplift. Two other anomalies (C 2 and E 4 anomalies), characterized by both moderately amplitude magnetic susceptibility and elevated soil gas hydrocarbons, occur near fault zones in the Cuoni Donghu synclinorium. These latter anomalies display characteristics of hydrocarbon microseepage anomalies commonly associated with oil and gas accumulations. Their presence in the Cuoni Donghu synclinorium suggests that parts of the Qiangtang basin may have significant petroleum potential. | Liu Qingsheng Department of Geophysics, China University of Geosciences, Wuhan 430074 The State Key Laboratory of Oil/Gas Reservoir Geology and Exploitation of China, Institute of Chengdu Technology, Chengdu 610059 Wu Qifan Li Haixia Department o | 2001 | Journal of China University of Geosciences2001，12，2： | 1 |
| 7 | Almandine megacrysts from Yingfengling Cenozoic basalt in Leizhou Peninsula and their parental magma origin显示文摘The garnet megacrysts from Yingfengling basalts are characterlzed by high FeO (>20%), CaO (7.02% -8.16%) and low MgO (5.88%-10.87%). Significant composition variations are observed in these megacrysts, of which Ni, V, Sc, Co, and HREE are positively correlated with their Mg# and Zr, Hf, Ga, Y, Sr, Nb, Zn and LREE-MREE are negatively correlated with Mg#. Megacryst parent magma is a highly evolved residual melt with strongl depletion in Ti, Sr, Hf, Nb and HREE. This parental magma was generated by more than 60% of crystallization fractionation of clinopyroxene, garnet, plagioclase and ilmenite from quartz tholeiitic magma. It has not erupted to the surface, but stayed at the upper mantle and formed the megacrystic cumulate. Megacrysts and their host basalt are in disequilibrium. | YU Jinhai & S. Y. O’Reilly1. National Key Laboratory of Metallogenic Mechanism of Endogenetic Deposits, Department of Earth Sciences, Nanjing University, Nanjing 210093, China 2. National Key Center of GEMOC, Department of Earth and Planetary Sciences, Macquarie University, North Ryde, NSW 2109, Australia | 2001 | Chinese Science Bulletin2001，46，14： | 1 |
| 8 | Synthcsis, Structure and Magnetochemistry of a New Hexanuclear Manganese Oxide Complex of the Formula [Mn_6O_2 (O_2CPh)_(10)(CH_3CN)_4]显示文摘The reported X-ray structure and magnetochemical properties of [Mn6O2 (OCPh)10, (CH3CN)4], effectively derived from [NBu4][Mn4O2(O2CPh)9 (H2O)] with equivalent of tren in CH3CN is shown. | Jin AN Zhi Da CHEN Jiang BIAN Shi Xi WANG Guang Xian XU (Department of Chemistry, Peking University, Beijing 100871)(State Key Laboratory of Rare Earth Materials Chemistry and Applications, Rare Earth Materials and Bio-inorganic Chemistry Laboratory o | 1999 | Chinese Chemical Letters1999，10，8： | 0 |
| 9 | Studies on Free Radical EPR, Superoxide Dismutase Water-soluble Lipidperoxide in Tears显示文摘StudiesonFreeRadicalEPR,SuperoxideDismutaseWater┐solubleLipidperoxideinTearsYUANYi*,ZHAOShi-hong,YANGShou,CUIYa-nanandZHAN... | YUAN Yi*, ZHAO Shihong, YANG Shou, CUI Yanan and ZHANG Reixue(Ophthalmic Department, Center Laboratory of the Third Clinical Hospital, Norman Bethune University of Medical Sciences, 130021 Surveying and Determining o | 1998 | Chemical Research in Chinese Universities1998，14，2： | 0 |
| 10 | Synthesis and Structure of Ru (pap)_2Cl_2 · 4EtOH显示文摘SynthesisandStructureofRu(pap)_2Cl_2·4EtOH￥ZhaoWei-Jun;ZhangShu-Ji;DengYi;ZhangZheng-Zhi;MaYan-Feng;HuangWei-Ping;WangHong-Gen... | Zhao Wei-Jun Zhang Shu-Ji Deng Yi Zhang Zheng-Zhi Ma Yan-Feng Huang Wei-Ping Wang Hong-Gen(Department of Chemistry, Institute of Elemento-Organic Chemisty,and Central Laboratory,Nankai University, Tianjin 300071, China) Liu Qiu-Tian(State Key Laboratory o | 1996 | Chinese Journal of Structural Chemistry1996，15，1： | 0 |
| 11 | Dilepton production in baryon-rich quark-gluon matter显示文摘From the full stopping scenario and considered the Drell-Yang background, the rapidity dependence of the dilepton production from the central collision 197Au + 197Au has been studied in the baryon-rich quark-gluon matter by using a relativistic hydrodynamic model.It can be found that the dilepton yield is strongly suppressed as increasing the rapidity. Such a characteristic signaling the formation of the baryon-rich quark-gluon matter can be tested in future experiments at CERN and Brookhaven. | He Ze-Jun Zhang Jia-Ju Jiang Wei-Zhou and Liu Bo (CCAST World Laboratory P. O. Box 8730, Beijing 100080)(Shanghai Institute of Nuclear Research, the Chinese Academy of Sciences, Shanghai 201800)(Computing Center of Shanghai Branch, the Chinese Academy o | 1998 | Nuclear Science and Techniques1998，9，2： | 0 |
| 12 | SYNTHESIS OF 2,2''-BIFLAVANONES显示文摘A new approach to the synthesis of 2,2″-biflavanones by the reductivedimerization of flavones is reported.The racemate and meso compounds of eachbitlavanone have been separated and their structures have been determined on the basis oftheir spectral data. | Yu Lin LI Fang Jie ZHANG Laboratory of Applied Organic Chemistry,Institute o f Organic Chemistry,Lanzhou University,Lanzhou,730060 | 1991 | Chinese Chemical Letters1991，2，4： | 0 |
| 13 | Screening of Anti-SIV Drugs from Chinese Medicinal Herbs显示文摘ScreeningofAnti-SIVDrugsfromChineseMedicinalHerbsGuanChong-fen(关崇芬);WangYi-zhe(王忆浙);(InstituteofBasicTheory,ChinaAcademyofTra... | Guan Chong-fen(关崇芬) Wang Yi-zhe(王忆浙) (Institute of Basic Theory, China Academy of Traiditional Chinese Medicine, Beijing)(100700)Wu Xiao-xian (吴小闲) He Fu-qiu(何伏秋) Tu Xin-ming(涂新明) (Institute of Laboratory Animal Science, Chinese Academy o | 1995 | Chinese Journal of Integrative Medicine1995，1，1： | 0 |
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