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| 1 | Non-alcoholic fatty liver disease and obesity: Biochemical, metabolic and clinical presentations显示文摘Non-alcoholic fatty liver disease(NAFLD)is the most common liver disease in the world.Presentation of the disease ranges from simple steatosis to non-alcoholic steatohepatitis(NASH).NAFLD is a hepatic manifestation of metabolic syndrome that includes central abdominal obesity along with other components.Up to80%of patients with NAFLD are obese,defined as a body mass index(BMI)>30 kg/m2.However,the distribution of fat tissue plays a greater role in insulin resistance than the BMI.The large amount of visceral adipose tissue(VAT)in morbidly obese(BMI>40 kg/m2)individuals contributes to a high prevalence of NAFLD.Free fatty acids derived from VAT tissue,as well as from dietary sources and de novo lipogenesis,are released to the portal venous system.Excess free fatty acids and chronic low-grade inflammation from VAT are considered to be two of the most important factors contributing to liver injury progression in NAFLD.In addition,secretion of adipokines from VAT as well as lipid accumulation in the liver further promotes inflammation through nuclear factor kappa B signaling pathways,which are also activated by free fatty acids,and contribute to insulin resistance.Most NAFLD patients are asymptomatic on clinical presentation,even though some may present with fatigue,dyspepsia,dull pain in the liver and hepatosplenomegaly.Treatment for NAFLD and NASH involves weight reduction through lifestyle modifications,anti-obesity medication and bariatric surgery.This article reviews the available information on the biochemical and metabolic phenotypes associated with obesity and fatty liver disease.The relative contribution of visceral and liver fat to insulin resistance is discussed,and recommendations for clinical evaluation of affected individuals is provided. | Sandra Milic Davorka Lulic Davor Stimac | 2014 | World Journal of Gastroenterology2014,20,28: | 52 |
| 2 | Implant dentistry in undergraduate dental curricula in South-East Asia:forum workshop at the University of Hong Kong,Prince Philip Dental Hospital,19-20 November 2010显示文摘 | Lang NP Bridges SM Lulic M | 2011 | J Investig Clin Dent2011,2,3: | 1 |
| 3 | Cyclosporine-A as a neuroprotective agent against stroke: its translation from laboratory research to clinical application 显示文摘 | Osman MM Lulic D Glover L | 2011 | Neuropeptides2011,45,6: | 1 |
| 4 | Ante's (1926) law revisited:a systematic review on survival rates and complications of fixed dental prostheses (FDPs) on severely reduced periodontal tissue support显示文摘 | Lulic M Bragger U Lang NP | 2007 | Clln Oral Implants Res2007,18,3: | 1 |
| 5 | Mechanisms in experimental venous valve failure and their modification by Daflon 500 mg 显示文摘 | Pascarella L Lulic D Penn AH | 2008 | Eur J Vase Endovasc Surg2008,35,1: | 1 |
| 6 | Ante's (1926) law revisi- ted:a systematic review on survival rates and complications of fixed dental prostheses (FDPs) on severely reduced periodontal tissue support显示文摘 | Lulic M Brfigger U Lang NP | 2007 | Clin Oral Implants Res2007,18,3: | 1 |
| 7 | Cyclosporine-A as a neuroprotective agent against stroke: its translation from laboratory research to clinical application 显示文摘 | Osman MM Lulic D Glover L | 2011 | Neuropeptides2011,45,6: | 1 |
| 8 | Do mucositis lesions around implants differ from gingivitis lesions around teeth显示文摘 | LANG N P BOSSHARDT D D LULIC M | | 0,,11: | 1 |
| 9 | Ante's (1926) law revisited: a systematic review on survival rates and compli- cations of fixed dental prostheses (FDPs) on severely reduced periodontal tissue support 显示文摘 | Lulic M Bragger U Lang NP | 2007 | Clin Oral Implants Res2007,18,3: | 1 |
| 10 | Mobile phone in the chain of survival显示文摘 | Kovic I Lulic I | 2011 | Resuscitation2011,82,77: | 1 |
| 11 | Determination of Cr ( Ⅲ) and Cr(VI) in industrial and nvironmental liquid samples by EDXIRF method 显示文摘 | Visnja Orescanin tipe Lulic Mirta Rubcic | 2004 | Analytica Chimica Acta2004,527,: | 1 |
| 12 | Improved method for the separation of radioactive strontium from various samples by mixed solvent anion exchange 显示文摘 | Grahek Z Kosutic K Lulic S | 1999 | Journal of Radioanalytical and Nuclear Chemistry1999,242,1: | 1 |
| 13 | Do mucositis lesions around implants differ from gingivitis lesions around teeth?显示文摘 | Lang NP Bosshardt DD Lulic M | 2011 | J Clin Periodontol2011,38,11: | 1 |
| 14 | Cyelosporine-A as a neuroprotective agent against stroke: its translation from laboratory research to clinical application 显示文摘 | Osman MM Lulic D Glover L | 2011 | Neuropep- tides2011,45,6: | 1 |
| 15 | implant surface modifications and implant diameter显示文摘 | Han J Lulic M Lang NP Factors influericing resonance frequeency analysis assessed by Osstell mentor during tisue integration: Ⅱ | 2010 | Clin Oral Implants Res2010,21,6: | 1 |
| 16 | Mechanisms in experimental venous valve failure and their modification by Daflon 500 mg显示文摘 | PASCARELLA L LULIC D PENN AH | 2008 | Eur J Vasc Endovasc Surg2008,35,1: | 1 |
| 17 | The optimization ofcrankshaft offset of spark ignition engine显示文摘 | TOMIC R SJERIC M LULIC Z | 2012 | Journal of Trendsin the Development of Machinery and Associated Technology2012,16,1: | 1 |
| 18 | RELIGIOUS MINORITIES IN THE MEDIA SPACE OF THE REPUBLIC OF CROATIA显示文摘 | Mira Lulic Nives Mazur Kumric | 2014 | US-China Law Review2014,11,1: | 0 |