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| 1 | Review of 10 years of research on breast cancer patients:Focus on indoleamine 2,3-dioxygenase显示文摘Therapeutic manipulation of the immune system in cancer has been an extensive area of research in the field of oncoimmunology.Immunosuppression regulates antitumour immune responses.An immunosuppressive enzyme,indoleamine 2,3-dioxygenase(IDO)mediates tumour immune escape in various malignancies including breast cancer.IDO upregulation in breast cancer cells may lead to the recruitment of regulatory T(T-regs)cells into the tumour microenvironment,thus inhibiting local immune responses and promoting metastasis.Immunosuppression induced by myeloid derived suppressor cells activated in an IDOdependent manner may enhance the possibility of immune evasion in breast cancer.IDO overexpression has independent prognostic significance in a subtype of breast cancer of emerging interest,basal-like breast carcinoma.IDO inhibitors as adjuvant therapeutic agents may have clinical implications in breast cancer.This review proposes future prospects of IDO not only as a therapeutic target but also as a valuable prognostic marker for breast cancer. | Kashif Asghar Asim Farooq Bilal Zulfiqar Asif Loya | 2021 | World Journal of Clinical Oncology2021，12，6： | 2 |
| 2 | Mode of inhibition of HIV-1 reverse transcriptase by polyacetylenetriol,a novel inhibitor of RNA-and DNA-directed DNA polymerases显示文摘 | Loya S Rudi A Kashman Y | 2002 | Biochem J2002，362，3： | 1 |
| 3 | Beetle pollination and floral thermogenicity in Magnolia tamaulipana ( Magnoli- aceae) 显示文摘 | DIERINGER G LARA M LOYA L | 1999 | International Journal of Plant Sciences1999，160，1： | 1 |
| 4 | Soil respiration in northern forests exposed to elevated atmospheric carbon dioxide and ozone显示文摘 | PREGITZER K LOYA W KUBISKE M | 2006 | Oecologia2006，148，3： | 1 |
| 5 | Bidirectional sex change in mushroom stony corals显示文摘 | Loya Y Sakai K | 2008 | Proceedings of the Royal Society of London B2008，275，1649： | 1 |
| 6 | Illimaquinone, a selec- tive inhibitor of the RNase H activity of human irnmunode- fieiency virus type 1 reverse transeriptase显示文摘 | Loya S Tal R Kashman Y | 1990 | Antimicrob Agents Chemother1990，34，10： | 1 |
| 7 | Speciation ver?sus phenotipic plasticity in coral inhabiting barnacles: Darwin's observation in a phylogenetic context显示文摘 | Mokady 0 Y Loya Y Achituv E et a1 | 1999 | Mol Evol1999，49，： | 1 |
| 8 | Soil carbon and nitrogen across a chronsequence of woody plant expansion in North Dakota显示文摘 | Springsten A Loya W Liebig M | 2010 | Plant Soil2010，，328： | 1 |
| 9 | Profile of submitral left ventricular aneurysms in Indian patients 显示文摘 | Sharma S Daxini BV Loya YS | 1990 | Indian Heart J1990，42，： | 1 |
| 10 | Micro-RNA-221 overexpression accelerates hepatocyte prolife-ration during liver regeneration 显示文摘 | Yuan Q Loya K Rani B | 2013 | Hepatology2013，57，1： | 1 |
| 11 | Clathsterol, a novel anti-HIV-1 RT sulfated sterol from the sponge Clathria species显示文摘 | Rudi A Yosief T Loya S | 2001 | J Nat Prod2001，64，11： | 1 |
| 12 | Vibration characteristics of functionally graded cylindrical shells under various boundary conditions 显示文摘 | Pradhana S C Loya C T Lama K Y | 2000 | Applied Acoustics2000，61，： | 1 |
| 13 | MicroRNA-221 overexpression accelerates hepatocyte proliferation during liver regeneration显示文摘 | Yuan Q Loya K Rani B | 2013 | Hepatology2013，57，1： | 1 |
| 14 | ABA promotes quiescence of the quiescent centre and suppresses stem cell differentiation in the Arabidopsis primary root meristem 显示文摘 | Zhang H Han W De Smet I Talboys P Loya R Hassan A Rong H Jürgens G Paul Knox J Wang M H | 2010 | The Plant Journal2010，64，5： | 1 |
| 15 | Mode of inhibition of HIV reverse transcriptase by 2-hexaprenyl-hydroquinone, a novel general inhibitor of RNA- and DNA-directed DNA polymerases显示文摘 | Loya S Rudi A Kashman Y | 1997 | Biochem J1997，324，： | 1 |
| 16 | Effects of water turbidity and sedimentation on the community structure of Puerto Rican reefs 显示文摘 | Loya Y | 1976 | Bull Mar Sci1976，26，： | 1 |
| 17 | Soil respiration in northern forests exposed to elevated atmospheric carbon dioxide and ozone显示文摘 | Pregitzer K Loya W Kubiske M | 2006 | Oeeologia2006，148，3： | 1 |
| 18 | Corneal topographic changes after retinal and vitreous surgery显示文摘 | Weinberger D Lichter H Loya N | 1999 | Ophthalmology1999，106，8： | 1 |
| 19 | Peyssonols A and B, two novel inhibitors of the reverse transcriptases of human immunodeficiency virus types 1 and 2显示文摘 | Loya S Bakhanashvili M Kashman Y | 1995 | Arch Biochem Biophys1995，316，2： | 1 |
| 20 | Natural frequencies for bending vibrations of Timoshenko cracked beams显示文摘 | Loya J A Rubio L Fernandez-Saez J | 2006 | Journal of Sound and Vibration2006，290，35： | 1 |
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