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144篇 您的检索式：作者名="LOUKAS A"

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	题名	作者	年代	出处	被引量
1	Schistosoma mansoni proteins attenuate gastrointestinal motility disturbances during experimental colitis in mice显示文摘AIM:To investigate the therapeutic effect of Schistosoma mansoni(S.mansoni) soluble worm proteins on gastrointestinal motility disturbances during experimental colitis in mice. METHODS:Colitis was induced by intrarectal injection of trinitrobenzene sulphate(TNBS) and 6 h later,mice were treated ip with S.mansoni proteins.Experiments were performed 5 d after TNBS injection.Inflammationwas quantified using validated inflammation parameters. Gastric emptying and geometric center were measured to assess in vivo gastrointestinal motility.Peristaltic activity of distal colonic segments was studied in vitro using a modified Trendelenburg set-up.Cytokine profiles of T-lymphocytes isolated from the colon were determined by real time reverse transcriptase-polymerase chain reaction. RESULTS:Intracolonic injection of TNBS caused severe colitis.Treatment with S.mansoni proteins significantly ameliorated colonic inflammation after 5 d.TNBS did not affect gastric emptying but significantly decreased the geometric center and impaired colonic peristaltic activity 5 d after the induction of colitis.Treatment with S.mansoni proteins ameliorated these in vivo and in vitro motility disturbances.In addition,TNBS injection caused a downregulation of effector T cell cytokines after 5 d,whereas a S.mansoni protein effect was no longer observed at this time point. CONCLUSION:Treatment with S.mansoni proteins attenuated intestinal inflammation and ameliorated motility disturbances during murine experimental colitis.	Nathalie E Ruyssers Benedicte Y De Winter Joris G De Man Natacha D Ruyssers Ann J Van Gils Alex Loukas Mark S Pearson Joel V Weinstock Paul A Pelckmans Tom G Moreels	2010	World Journal of Gastroenterology2010，16，6：	11
2	Spatial variability of ref- erence evapotranspiration in Greece显示文摘	Dalezios N R Loukas A Bampzelis D	2002	Physics and Chemistry of the Earth2002，27，：	1
3	Funcational characterization of the D188V mution in neuronal voltage-gated sodium channel causing generalized epilepsy with febrile seizures plus(GEFS^+)显示文摘	Cossette P Loukas A Lafreniere R G	2003	Epilepsy Res2003，53，12：	1
4	Current status of vaccines for schistosomia- sis显示文摘	McManus DP Loukas A	2008	Clin Microbiol Rev2008，21，1：	1
5	HLA in coeliac disease: unravelling the complex genetics of a complex disorder 显示文摘	Louka A S Sollid L M	2003	Tissue Antigens2003，61，2：	1
6	Schistosome membrane proteins as vaccines 显示文摘	Loukas A Tran M Pearson MS	2007	Int J Parasitol2007，37，3：	1
7	Identification of a novel opioid peptide from human α sl casein显示文摘	Kampa M Loukas S Hatzoglou A	1996	J Biochem1996，319，：	1
8	Branches of the petrous and cavernous segments of the internal carotid artery显示文摘	Tubbs RS Hansasuta A Loukas M	2007	Clin Anat2007，20，6：	1
9	Changes in use of ciga- rettes and non-cigarette alternative products among college students 显示文摘	Loukas A Ba/anova M Fernandez A eta	2015	Addict Behav2015，49，：	1
10	Characterization of the antioxidant enzyme,thioredoxin peroxidase,from the carcinogenic human liver fluke,Opisthorchis viverrini显示文摘	Suttiprapa S Loukas A Laha T	2008	Mol Biochem Parasitol2008，160，2：	1
11	Schistosomiasis vaccine discovery using immunomies 显示文摘	Driguez P Doolan DL Loukas A	2010	Parasit Vector2010，3，：	1
12	Chiari's network:review of the literature显示文摘	Loukas M Sullivan A Tubbs RS	2010	Surg Radiol Anat2010，3，：	1
13	Schistosome membrane proteins as vaccines 显示文摘	Loukas A Tran M Pearson MS	2007	Int J Parasitol2007，37，34：	1
14	Schistosome membrane proteins as vaccines显示文摘	Loukas A Tran M Pearson MS	2007	IntJ Parasitol2007，37，34：	1
15	Climate change implications on flood response of a mountainous watershed显示文摘	LOUKAS A VASILIADES L DALEZIOS N	2004	Water Air & Soil Pollution Focus2004，4，45：	1
16	Identification of greater occipital nerve landmarks for the treatment of occipital neuralgia 显示文摘	Loukas M El-Sedfy A Tubbs RS	2006	Folia Morphol(Warsz)2006，65，4：	1
17	A modeling system of the evaluation of water resources management strategies in Thessaly, Greece 显示文摘	LOUKAS A MYLOPOULOS N VASILIADES L	2007	Water Resources Management2007，21，：	1
18	Current status of vaccines forschistosomiasis显示文摘	McManus D P Loukas A	2008	Clin Microbiol Rev2008，21，：	1
19	Saposin-like proteins are expressed in the gastrodermis of Schistosoma mansoni and are immunogenic in natural infections显示文摘	Don TA Bethony JM Loukas A	2008	Int J Infect Dis2008，12，6：	1
20	Probabilistic analysis of drought spatiotemporal characteristics in Thessaly region,Greece显示文摘	Loukas A Vasiliades L	2004	Natural Hazards and Earth System Science2004，4，：	1

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