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| 1 | 血管紧张素Ⅱ诱导的高血压所引起的T淋巴细胞活化与血管炎症的中枢和外周机制显示文摘研究者先前就发现,T淋巴细胞对血管紧张素Ⅱ(AngiotensinⅡ,AngⅡ)诱导的高血压的发生发展是必需的,但是,高血压发生过程中的T细胞活化机制尚不明确。该文研究者探讨了中枢神经系统和血压升高在AngⅡ导致的T细胞活化与血管炎症中的作用。 | 张玲玉 叶鹏 Marvar PJ Thabet SR Guzik TJ Lob HE McCann LA Weyand C Gordon FJ Harrison DG | 2010 | 中华高血压杂志2010，18，12： | 15 |
| 2 | Genome and metabolic engineering in non-conventional yeasts:Current advances and applications显示文摘Microbial production of chemicals and proteins from biomass-derived andwaste sugar streams is a rapidly growing area of research and development.While the model yeast Saccharomyces cerevisiae is an excellent host for the conversion of glucose to ethanol,production of other chemicals from alternative substrates often requires extensive strain engineering.To avoid complex and intensive engineering of S.cerevisiae,other yeasts are often selected as hosts for bioprocessing based on their natural capacity to produce a desired product:for example,the efficient production and secretion of proteins,lipids,and primary metabolites that have value as commodity chemicals.Even when using yeasts with beneficial native phenotypes,metabolic engineering to increase yield,titer,and production rate is essential.The non-conventional yeasts Kluyveromyces lactis,K.marxianus,Scheffersomyces stipitis,Yarrowia lipolytica,Hansenula polymorpha and Pichia pastoris have been developed as eukaryotic hosts because of their desirable phenotypes,including thermotolerance,assimilation of diverse carbon sources,and high protein secretion.However,advanced metabolic engineering in these yeasts has been limited.This review outlines the challenges of using non-conventional yeasts for strain and pathway engineering,and discusses the developed solutions to these problems and the resulting applications in industrial biotechnology. | Ann-Kathrin Lobs Cory Schwartz Ian Wheeldon | 2017 | Synthetic and Systems Biotechnology2017，2，3： | 3 |
| 3 | Acinetobacterbaurnannii re- spiratory isolates in ventilated patients are associated with prolonged hospital stay 显示文摘 | Lob LC Yii CT Lai KK etal | 2006 | Clin Microbiol Infect2006，12，59： | 1 |
| 4 | C-reactive protein is a risk ind-icator for atrial fibrillation after myocardial revascularization显示文摘 | LOB Fijinheer R N ierich AP | 2005 | Ann Thoral Surg2005，79，： | 1 |
| 5 | Occupational and consumer risk estimates for nanoparticles emitted by laser printers 显示文摘 | Hanninen O Braske H I Lob M | 2010 | Journal of Nanoparticle Research2010，12，1： | 1 |
| 6 | Relationship of high-sensitivity C-reactive protein to prognosis and other prognostic markers in outpatients with heart failure 显示文摘 | Windram JD Lob PH Rigby AS | 2007 | Am Heart J2007，153，6： | 1 |
| 7 | Serotypes of 'Pasteurella' anatipestifer isolates from ducks in Singapore: a proposal of new serotypes显示文摘 | Lob H Teo TP Tan HC | 1992 | Avian Pathology1992，21，3： | 1 |
| 8 | Mixed-frame and stationary- frame repetitive control schemes for compensating typical load and grid harmonics显示文摘 | Lob P C Tang Y Blaabjerg F | 2011 | IET Power Electronics2011，4，2： | 1 |
| 9 | Automatic classification of patent docu- ments fnr TRIZ users显示文摘 | Lob H T He C Shen L | 2006 | World Patent Information2006，28，1： | 1 |
| 10 | Timing of levothyroxine administration affects serum thyrotropin concentration显示文摘 | Bach-Huynh TG Nayak B Lob J | 2009 | J Clin Endocrinol Metab2009，94，： | 1 |
| 11 | Oxidative stress: apoptosis in neuronal injury显示文摘 | Lob KP Huang SH De Silva R et a l | 2006 | Curr Alzheimer Res2006，3，： | 1 |
| 12 | Inflammation,Immunity,and Hypertension显示文摘 | Harrison DG Guzik TJ Lob HE | 2011 | Hypertension2011，57，： | 1 |
| 13 | Pretreatment imaging can be used to select imaging guidance, ultrasound alone versus CT plus ultrasound, for percutaneous renal radiofrequency ablation显示文摘 | Mcgahan JP Lob S Fitzgerald E | 2011 | AJR2011，197，： | 1 |
| 14 | Ionic liquid synthesis in a micro- structured reactor for process intensification 显示文摘 | Renken A Hessel V Lob P | 2007 | Chem Eng Process2007，46，： | 1 |
| 15 | Interleukin 17 pro- motes angiotensin II-induced hypertension and vascular dysfune- tion显示文摘 | Madhur MS Lob HE McCann LA | 2010 | Hypertension2010，55，2： | 1 |
| 16 | Is IDO a key enzyme bridging the gap between tumor escape and tolerance induction显示文摘 | Lob S Konigsrainer A | 2008 | Langenbecks Arch Surg2008，393，6： | 1 |
| 17 | Nuclear factor kappaB signaling in opioid functions and receptor gene expression 显示文摘 | Chert YL Law PY Lob HH | 2006 | J Neuroimmune Pharmaco12006，1，3： | 1 |
| 18 | Optical fiber dissolved oxygen sensor based on Pt(ll) complex and core-shell silica nanoparticles incorporated with sol-gel matrix显示文摘 | 3hua C S Lob Y L | 2010 | Sensors and Actuators B2010，151，1： | 1 |
| 19 | Interleukin 17 Promotes Angiotensin Ⅱ-induced Hypertension and Vascular Dysfunction显示文摘 | Madhur MS Lob HE McCann LA | | 0，，02： | 1 |
| 20 | Inflammation, Immunity and Hypertension 显示文摘 | Harrison DG Guzik TJ Lob H | 2011 | Hypertension2011，57，2： | 1 |
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