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74篇 您的检索式:作者名="LIM CP"
    题名 作者 年代 出处 被引量
1二甲双胍之后的选择--二线降糖药物应如何选择?聚焦磺脲类药物:联合应用与复方制剂显示文摘目的:本综述旨在评估2型糖尿病的二线治疗药物,尤其是磺脲类药物的临床应用问题,对磺脲类药物和二甲双胍联合用药与复方制剂进行比较。方法:从数据库中检索大量的英文论著、临床实践指南以及相关参考文献。结果:磺脲类药物与二甲双胍联用可以同时改善胰岛素抵抗和胰岛素分泌不足。与噻唑烷二酮类药物、二肽基肽酶-4(dipeptidyl peptidase-4,DPP-4)抑制剂、胰高血糖素样肽-1(glucagonlike peptide 1,GLP-1)受体激动剂和胰岛素相比,磺脲类药物更加有效且价格低廉。磺脲类药物主要的不良反应为低血糖,与二甲双胍联用体重增加不明显。低剂量的磺脲类/二甲双胍的复方制剂可以更好地控制血糖,减少不良反应,具有更高的患者依从性,并且复方制剂比联合用药价格更低廉。结论:磺脲类药物作为二线药物与二甲双胍联合治疗可以针对2型糖尿病的两个主要发病环节,即胰岛素抵抗和胰岛素分泌不足,临床使用有效、安全、经济。与联合用药相比,固定剂量的复方制剂可提高患者的依从性,无论是原研药物还是仿制药物的复方制剂,均价格低廉、疗效更佳。杨进(译) 蔡晓凌(校) Lim PC Chong CP 2017药品评价2017,14,3:6
2Co-management in marine fisheries: the Japanese experience显示文摘Lim CP Matsuda Y Shigemi Y 1995Coastal Management1995,23,:1
3Cefepime-associated throm- boeytopenia in a critically ill patient 显示文摘Lim PP Chong CP Aziz NA 2011Int J Clin Pharm2011,33,6:1
4Single-incision mini- slings versus standard midurethral slings in surgical manage- ment of female stress urinary incontinence : an updated sys- tematic review and meta-analysis of effectiveness and com- plications显示文摘Mostafa A Lim CP Hopper L 2014Eur Uro12014,65,2:1
5Over-expression of MAGED4B increases cell migration and growth in oral squamous cell carcinoma and is associated with poor disease outcome显示文摘Chong CE Lim KP Gan CP 2012Cancer Lett2012,321,1:1
6STAT3 regulates microtubules by antagonizing the depolymerizatian activity of stathmin显示文摘 Lin BH Lim CP 2006J Cell Biol2006,172,2:1
7N terminal pro-brain na- triuretic peptide and angiotensinconverting enzyme-2 levels and their association with postoperative cardiac complications after e- mergency orthopedic surgery显示文摘Chong CP Lim WK Velkoska E 2012Am J Cardiol2012,109,9:1
8Characterization of a Helicobacter pylori vaccine candidate by proteome techniques 显示文摘Macatee CP Lim MY Fung K 1998J Chromatography B1998,714,2:1
9Investigation of matrix metalloproteinases,MMP-2 and MMP-9,in plasma reveals a decrease of MMP-2 in Alzheimer's disease显示文摘Lim NK Villemagne VL Soon CP Journal of Alzheimer's Disease0,,:1
10Combination of essentialoils and antibiotics reduce antibiotic resistance in plasmid-con-ferred multidrug resistant bacteria显示文摘YAP PSX LIM SHE HU CP 2013Phytomedicine2013,20,89:1
11Over expression of MAGEIMb increases cell migration and growth in oral squamous cell carcino- ma and is associated with poor disease outcome 显示文摘Chang CE Lim KP Gan CP 2012Cancer Lett2012,321,1:1
12Should a hysterosalpin- gogram be a first-line investigation to diagnose female tubal sub- fertility in the modem subfertility workup? 显示文摘Lim CP Hasafa Z Bhattacharya S 2011Hum Repmd2011,26,5:1
13Structure, function and regulation of STAT proteins 显示文摘Lim CP Cao X 2006Mol Biosyst2006,201,:1
14Use of artificial neural networks to predict drug dissolution profiles and evaluation of network performance using similarity factor 显示文摘Peh KK Lim CP Quek SS 2000Pharm Res2000,17,1:1
15Structure,function,and regulation of STAT proteins显示文摘Lim CP Cao X 2006Mol Biosyst2006,2,11:1
16Peripartum cardiomyopathy : experience in an Asiantertiary centre显示文摘Lim CP Sim DK 2013Singapore Med J2013,54,1:1
17Prophlactic and periopera- tive replacement therapy for acquired factor XIII deficiency 显示文摘Lim W Moffat K Hayward CP 2004J Thmmb Haemost2004,2,6:1
18Identification of potential diagnostic and vaccine candidates of Helicobacter pylori by two- dimensional gel electrophoresis, sequence analysis, and serum profiling显示文摘McAtee CP Lim MY Fung K 1998Clin Diagn Lab Immunol1998,5,:1
19Single-incision minislings versus standard midurethral slings in surgical management of female stress urinary incontinence: A Meta-analysis of effectiveness and eomplications显示文摘Abdel-Fattah M Ford JA Lim CP 2011Eur Urol2011,60,3:1
20Single-incision mini-slings versus standard midurethral slings in surgical man- agement of female stress urinary incontinence: an updated sys- tematic review and meta-analysis of effectiveness and complica- tions显示文摘MOSTAFA A LIM CP HOPPER L 2014EurUrol2014,65,2:1
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