|
|
|
题名
|
作者
|
年代
|
出处
|
被引量
|
| 1 | The functions of breast cancer susceptibility gene 1 ( BRCA1 ) product and its associated proteins显示文摘 | Irminger - Finger I Siegel BD Leung WC | 1999 | Biol Chem1999，380，2： | 1 |
| 2 | In vitro and in vivo anti-tumor effects of Astragalus membranaceus显示文摘 | Cho WC Leung KN | 2007 | Cancer Lett2007，252，： | 1 |
| 3 | Rapid quantification of hepatitis B virus DNA by real-time PCR using fluorescent hybridization probes显示文摘 | Ho SK Yam WC Leung EK | 2003 | J Med Microbiol2003，52，： | 1 |
| 4 | Rapid aneuploidy screening (FISH or QF-PCR ): the changing scene in prenatal diagnosis? 显示文摘 | Leung WC Lau ET Lao T | 2004 | Expert Rev Mol Diagn2004，4，3： | 1 |
| 5 | Proliferation to apoptosis ratio as a prognostic marker in adenocarcinoma of uterine cervix显示文摘 | Leung TW Xue WC Cheung ANY | 2004 | Gynecol Oncol2004，92，3： | 1 |
| 6 | A Chinese adolescent girl with Fechtner-like syndrome显示文摘 | Leung TF Tsoi WC Li CK | 1998 | Acta Paediatr1998，87，： | 1 |
| 7 | Competency based medical training:Review显示文摘 | Leung WC | 2002 | British Medical Journal2002，28，9： | 1 |
| 8 | Application of transcervical hysterofetoscopy and cord blood collection at first trimester termination of pregnancy for fetal abnormalities 显示文摘 | Chan BC Hui PW Leung WC | 2008 | Prenat Diagnosis2008，28，10： | 1 |
| 9 | Systematic investigation of the relationship between high myopia and polymorphisms of the MMP2,TIMP2,and TIMP3 genes by a DNA pooling approach显示文摘 | Leung KH Yiu WC Yap MK | 2011 | Invest Ophthalmol Vis Sci2011，52，6： | 1 |
| 10 | The functions of breast cancer suscep tibility gene 1 (BRCA1)product and its associated proteins 显示文摘 | Irminger-Finger I Siegel BD Leung WC | 1999 | Biol Chem1999，380，2： | 1 |
| 11 | Maternal hepatitis B infection and gestational diabetes mellitus显示文摘 | Lao TT Chan BC Leung WC | 2007 | J Hepatol2007，47，1： | 1 |
| 12 | In vitro and in vivo anti - tumor effects of Astrag - alusmembraneceus 显示文摘 | Cho WC Leung KN | 2007 | Cancer Lett2007，252，1： | 1 |
| 13 | Endoscopic submucosal dissection vs laparoscopic colorectal resection for early colorectal epithelial neoplasia显示文摘AIM: To compare the short term outcome of endoscopic submucosal dissection(ESD) with that of laparoscopic colorectal resection(LC) for the treatment of early colorectal epithelial neoplasms that are not amenable to conventional endoscopic removal. METHODS: This was a retrospective cohort study. The clinical data of all consecutive patients who underwent ESD for endoscopically assessed benign lesions that were larger than 2 cm in diameter from 2009 to 2013 were collected. These patients were compared with a cohort of controls who underwent LC from 2005 to 2013. Lesions that were proven to be malignant by initial endoscopic biopsies were excluded. Mid and lower rectal lesions were not included because total mesorectal excision, which bears a more complicated postoperative course, is not indicated for lesions without histological proof of malignancy. Both ESD and LC were performed by the same surgical unit with a standardized technique. The patients were managed according to a standard protocol, and they were closely monitored for complications after the procedures. All hospital records were reviewed, and the following data were compared between the ESD and LC groups: patient demographics, size and location of the lesions, procedure time, shortterm clinical outcomes and pathology results. RESULTS: From 2005 to 2013, 65 patients who underwent ESD and 55 patients who underwent LC were included in this study. The two groups were similar in terms of sex(P = 0.41) and American Society of Anesthesiologist class(P = 0.58), although patients in the ESD group were slightly older(68.6 ± 9.4 vs 64.6 ± 9.9, P = 0.03). ESD could be accomplished with a shorter procedure time(113 ± 66 min vs 153 ± 43 min, P < 0.01) for lesions of comparable size(3.0 ± 1.2 cm vs 3.4 ± 1.4 cm, P = 0.22) and location(colon/rectum:59/6 vs colon/rectum: 52/3, P = 0.43). ESD appeared to be associated with a lower short-term complication rate, but the difference did not reach statistical significance(10.8% vs 23.6%, P = 0.06). In the LC arm, a total of 22 complications occurred in 13 patients. A total of 7 complications occurred in the ESD arm, including 5 perforations and 2 episodes of bleeding. All perforations were observed during the procedure and were successfully managed by endoscopic clipping without emergency surgical intervention. Patients in the ESD arm had a faster recovery than patients in the LC arm, which included shorter time to resume normal diet(2 d vs 4 d, P = 0.01) and a shorter hospital stay(3 d vs 6 d, P < 0.01). CONCLUSION: ESD showed better short-term clinical outcomes in this study. Further prospective randomized studies will be required to evaluate the efficacy and superiority of colorectal ESD over LC. | Sophie SF Hon Simon SM Ng Tiffany CL Wong Philip WY Chiu Tony WC Mak WW Leung Janet FY Lee | 2015 | World Journal of Gastrointestinal Endoscopy2015，7，17： | 1 |
| 14 | Wilson's disease with chronic active hepatitis: monitoring by in vivo 31-phosphorus MR spectroscopy before and after medical treatment 显示文摘 | Chu WC Leung TF Chan KF | 2004 | AJR Am J Roentgenol2004，183，5： | 1 |
| 15 | Competency-based medical training review 显示文摘 | LEUNG WC | 2002 | BMJ2002，325，7366： | 1 |
| 16 | Serial sonographic findings of four fetuses with homozygous alpha-thalassemia-1 from 21 weeks onwards显示文摘 | Leung WC Oepkes D Seaward G | 2002 | Ultrasound in Obstetrics & Gynecology2002，19，1： | 1 |
| 17 | Ginsenoside Re of Panax ginseng possesses significant antioxidant and antihyperlipidemic efficacies in streptozotocin-induced diabetic rats显示文摘 | Cho WC Chung WS Lee SK Leung AW Cheng CH Yue KK | 2006 | Eur J Pharmacol2006，550，13： | 1 |
| 18 | Can amnio -polymerase chain reaction alone replace conventional cytogenetie study for women with positive biochemical screening for fetal Down syndrome? 显示文摘 | Leung WC Lau ET Lao TF Tang MH | 2003 | Obstet Gynecol2003，101，： | 1 |
| 19 | The functions of breast cancer susceptibility gene 1 (BRCA1) product and its associated proteins显示文摘 | Irminger-Finger I Siegel BD Leung WC | 1999 | Biological Chemistry1999，380，2： | 1 |
| 20 | Re-emergence of fatal human influenza A subtype H5N1 disease显示文摘 | Yu WC Leung CW | 2004 | Lancet2004，363，9409： | 1 |
您所在的机构暂未开通此部分的功能，请联系管理员