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| 1 | 在材料研制中的连续介质细观力学有限元建模现状评论显示文摘评述了机械载荷下材料力学行为有限元模拟的先进技术.分析了考虑材料微观及细观结构情况下,对材料变形、损伤、断裂进行模拟时各种方法的优缺点及发展前景.阐述了对材料行为模拟方法的发展,包括基本的及先进的方法,如体胞方法、真实结构模拟、粘结区模型等. | Leon L Mishnaevsky Jr Siegfried Schmauder 陈少华 魏悦广 | 2002 | 力学进展2002，32，3： | 9 |
| 2 | Breath test for differential diagnosis between small intestinal bacterial overgrowth and irritable bowel disease:An observation on non-absorbable antibiotics显示文摘AIM: To estimate the prevalence of small intestine bacterial overgrowth (SIBO) among patients with an earlier diagnosis of irritable bowel disease (IBS) in our geographical area, and to collect information on the use of locally acting non-absorbable antibiotics in the management of SIBO. METHODS: A non-interventional study was conducted in 73 consecutive patients with a symptom-based diagnosis.. RESULTS: When the patients underwent a 'breath test', 33 (45.2%) showed the presence of a SIBO. After treatment with rifaximin 1200 mg/d for seven days in 32 patients, 19 (59.4%) showed a negative 'breath test' one week later as well as a significant reduction of symptoms, thus confirming the relationship between SIBO and many of the symptoms claimed by patients. In the other 13 patients, 'breath test' remained positive, and a further cycle of treatment with ciprofloxacin 500 mg/d was given for 7 additional days, resulting in a negative 'breath test' in one patient only. CONCLUSION: (1) about half of the patients with a symptomatic diagnosis of IBS have actually SIBO, which is responsible for most of the symptoms attributed to IBS; (2) only a 'breath test' with lactulose (or with glucose in subjects with an intolerance to lactose) can provide a differential diagnosis between IBS and SIBO, with almost identical symptoms; and (3) the use of non-absorbable antibiotics may be useful to reduce the degree of SIBO and related symptoms; it must be accompanied, however, by the correction of the wrong alimentary habits underlying SIBO. | I Esposito A de Leone G Di Gregorio S Giaquinto L de Magistris A Ferrieri G Riegler | 2007 | World Journal of Gastroenterology2007，13，45： | 8 |
| 3 | 大气二氧化氮与每日总死亡率、心血管和呼吸系统疾病死亡率的短期关联:398个城市的多中心分析显示文摘目的:采用统一的分析方案,评估全球多个国家/地区的二氧化氮(NO_(2))与总死亡率、心血管和呼吸系统疾病死亡率之间的短期关联。研究设计:采用两阶段的时间序列分析方法、过度离散的广义线性模型和多水平meta分析。研究地点:22个低到高收入国家/地区的398个城市。主要结局指标:1973—2018年逐日总死亡人数(6280万人)、心血管疾病死亡人数(1970万人)和呼吸系统疾病死亡人数(550万人)。结果:平均而言,NO_(2)浓度在滞后1天(前1天)每增加10μg/m^(3),会导致总死亡率、心血管和呼吸系统疾病死亡率分别增加0.46%(95%可信区间0.36%~0.57%)、0.37%(0.22%~0.51%)、0.47%(0.21%~0.72%)。在对共污染物(PM_(10)、PM_(2.5)、臭氧、二氧化硫和一氧化碳)进行调整后,这些关联仍然很稳定。所有3种死因的暴露-反应曲线几乎是线性的,没有明显的阈值。在398个城市中,可归因于高过假定零水平的NO_(2)浓度造成的死亡比例为1.23%(95%可信区间0.96%~1.51%)。结论:这项多中心研究提供了关于NO_(2)短期暴露与总死亡率、心血管和呼吸系统死亡风险之间的独立和线性关联的关键证据,说明通过加强NO_(2)的控制和监管限制标准,可获得人群水平的健康收益。 | 孟夏 刘聪(校) 陈仁杰 郑湃(译) 阚海东(校) Francesco Sera Ana Vicedo-Cabrera Ai Milojevic Maria Guo Yuming Tong Shilu Micheline de Sousa Zanotti Stagliorio Coelh Paulo Hilario Nascimento Saldiva Eric Lavigne Patricia Matus Correa Nicolas Valdes Ortega Samuel Osorio Garcia Jan Kysely Ales Urban Hans Orru Marek Maasikmets Jouni J K Jaakkola Niilo Ryti Veronika Huber Alexandra Schneider Klea Katsouyanni Antonis Analitis Masahiro Hashizume Yasushi Honda Chris Fook Sheng Ng Baltazar Nunes João Paulo Teixeira Iulian Horia Holobaca Simona Fratianni Ho Kim Aurelio Tobias Carmeníniguez Bertil Forsberg ChristoferÅström Martina S Ragettli Yue-Liang Leon Guo Shih-Chun Pan Shanshan Li Michelle L Bell Antonella Zanobetti Joel Schwartz Tangchun Wu Antonio Gasparrini | 2021 | 英国医学杂志中文版2021，24，8： | 7 |
| 4 | Lichtenstein repair of inguinal hernia with Surgisis inguinal hernia matrix soft-tissue graft in immunodepressed patients显示文摘 | Catena F Ansaloni L Leone A | 2005 | Hernia2005，9，1： | 1 |
| 5 | Endocytic pathways and biological effects induced by UVB-dependent or ligand-dependent activation of the keratinocyte growth factor receptor显示文摘 | Belleudi F Leone L Aimati L | 2006 | FASEB J2006，20，2： | 1 |
| 6 | Incidence and susceptibility to therapy- related myeloid neoplasms 显示文摘 | Leone G Fianchi L Pagano L | 2010 | Chem Biol Interact2010，184，12： | 1 |
| 7 | Monitoring systems for steam turbine blade faults 显示文摘 | LEON R L TRAINOR K | 1990 | Sound and vibration1990，，2： | 1 |
| 8 | Nerve growth factor:from neurotrophin to neurokine显示文摘 | Levi-Montalcini R Skaper SD Dal Toso R Petrelli L Leon A | 1996 | Trends Neurosci1996，19，11： | 1 |
| 9 | From ideas to action: Creating a learning organization 显示文摘 | Wick C W Leon L S | 1995 | Human Resource Management1995，34，2： | 1 |
| 10 | Human pancreatic islets produce and secrete MCP-1/CCL2:relevance in human islet transplantation显示文摘 | PIEMONTI L LEONE BE NANO R | 2002 | Diabetes2002，51，1： | 1 |
| 11 | Multibeam backscatter as a tool for seafloor characterization and identification of oil spills in the Galicia Bank显示文摘 | MEDIALDEA T SOMOZA L LEON R | | 0，，01： | 1 |
| 12 | The age of multilevel converters arrives显示文摘 | L G Franquelo J Rodriguez J I Leon S Kouro R Portillo and M A M Prats | | 0，，02： | 1 |
| 13 | Genome-wide atlas of transcription through maize development显示文摘 | Sekhon R S Lin H Childs K L Hirsch C N Buell C R de Leon N Kaeppler S M | 2011 | The Plant Journal2011，66，4： | 1 |
| 14 | Probview: A flexible probabilistic database system 显示文摘 | Lakshmanan L V S Leone N Ross R | 1997 | ACM Transactions on Database Systems1997，22，3： | 1 |
| 15 | The prophylactic use of inferior vena cava filters in patients undergoing high-risk spinal surgery显示文摘 | Leon L Rodriguez H Tawk RG | 2005 | Ann Vasc Surg2005，19，3： | 1 |
| 16 | The dependency of microstructure and properties of nanostructured coatings on plasma spray conditions 显示文摘 | Leon L Shaw Daniel G | 2000 | Surface and Coatings Technology2000，130，： | 1 |
| 17 | Time course of cytokine,corticosterone,and tissue injury responses in mice during heat strain recovery显示文摘 | LEON L R BLAHA M D DUBOSE D A | 2006 | J Appl Physiol2006，100，4： | 1 |
| 18 | Human challenges in polar and space enviroument显示文摘 | SANDAL G M LEON G R PALINKAS L A | 2006 | Reviews in Environmental Science and Bio/technology2006，，5： | 1 |
| 19 | Optimized chemical stability and electrochemical performance of LiFePO4 composite materials obtained by ZnO coating显示文摘 | LEON B VICENTE C P T1RADO J L | 2008 | Journal of The Electrochemical Society2008，155，3： | 1 |
| 20 | Laparoscopic management of small bowel obstruction: indications and outcome显示文摘 | Leon E L Metzger A Tsiotos G G | 1998 | J Gastrointest Surg1998，2，2： | 1 |
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