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| 1 | The R-and AR-indices:Complementing the h-index显示文摘Based on the foundation laid by the h-index we introduce and study the R- and AR-indices. These new indices eliminate some of the disadvantages of the h-index, especially when they are used in combina-tion with the h-index. The R-index measures the h-core’s citation intensity, while AR goes one step further and takes the age of publications into account. This allows for an index that can actually in-crease and decrease over time. We propose the pair (h, AR) as a meaningful indicator for research evaluation. We further prove a relation characterizing the h-index in the power law model. | JIN BiHui LIANG LiMing Ronald ROUSSEAU Leo EGGHE | 2007 | Chinese Science Bulletin2007，52，6： | 116 |
| 2 | Treatment of coronary in-stent restenosis: a systematic review显示文摘冠的 stent 培植显著地改进了经皮的冠的干预并且启用了平凡汽球 angioplasty 的早复杂并发症的管理。然而,新复杂并发症伴随了这些改进:从 neointimal 增生产生的 in-stent 狭窄(ISR ) 。在冠的 angioplasty 以后的 ISR 当前是这个方法的主要限制之一,导致 exertional 心绞痛或急性冠的症候群的复发。在赤裸金属的 stent (BMS ) 以后的 ISR 的临床的发生培植是近似 20%-35% 。drug-eluting stents (DES ) 的使用在 ISR 的出现导致了进一步的减少到 5%-10% 。源于控制临床的研究的证据建议 DES 和 drug-eluting 汽球导管(初上舞台的人) 提供临床的最好, angiographic 导致 ISR 的处理。我们为 BMS-ISR 和 DES-ISR 拿了 pathophysiology,诊断和处理选择的系统的评论。我们讨论最近的 randomised 研究,比较为新 biovascular scafolds 和 scafold 狭窄的话题的 BMS 或 DES-ISR 处理,以及使用使用的不同 DES 或初上舞台的人。 | Leos Pleva Pavel Kukla Ota Hlinomaz | 2018 | Journal of Geriatric Cardiology2018，15，2： | 39 |
| 3 | Vascular invasion in pancreatic cancer:Imaging modalities,preoperative diagnosis and surgical management显示文摘Pancreatic cancer is associated with a poor prognosis,and surgical resection remains the only chance for curative therapy.In the absence of metastatic disease,which would preclude resection,assessment of vascular invasion is an important parameter for determining resectability of pancreatic cancer.A frequent error is to misdiagnose an involved major vessel.Obviously,surgical exploration with pathological examination remains the'gold standard'in terms of evaluation of resectability,especially from the point of view of vascular involvement.However,current imaging modalities have improved and allow detection of vascular invasion with more accuracy.A venous resection in pancreatic cancer is a feasible technique and relatively reliable.Nevertheless,a survival benefit is not achieved by curative resection in patients with pancreatic cancer and vascular invasion.Although the discovery of an arterial invasion during the operation might require an aggressive management,discovery before the operation should be considered as a contraindication.Detection of vascular invasion remains one of the most important challenges in pancreatic surgery.The aim of this article is to provide a complete review of the different imaging modalities in the detection of vascular invasion in pancreatic cancer. | Nicolas C Buchs Michael Chilcott Pierre-Alexandre Poletti Leo H Buhler Philippe Morel | 2010 | World Journal of Gastroenterology2010，16，7： | 29 |
| 4 | 食用菌主要病原真菌和细菌显示文摘食用菌已成为我国农业产业中的第五大作物。随着食用菌生产规模的扩大,病害日益严重,成为影响食用菌产量和品质的重要因素之一。本文概述了引起食用菌主要病害的病原真菌和细菌的种类、寄主范围、病害发生率以及发病症状,阐明了食用菌病害防治研究现状。同时也总结了一些病害的防治方法,为食用菌栽培、病害防治和抗病育种提供理论依据。 | 刘正慧 李丹 SOSSAH Frederick Leo 沈宏艳 OKORLEY Benjamin Azu 付永平 | 2018 | 菌物研究2018，16，3： | 30 |
| 5 | Gastric cancer: Current status of lymph node dissection显示文摘D2 procedure has been accepted in Far East as the standard treatment for both early(EGC) and advanced gastric cancer(AGC) for many decades. Recently EGC has been successfully treated with endoscopy by endoscopic mucosal resection or endoscopic submucosal dissection, when restricted or extended Gotoda's criteria can be applied and D1+ surgery is offered only to patients not fitted for less invasive treatment. Furthermore, two randomised controlled trials(RCTs) have been demonstrating the non inferiority of minimally invasive technique as compared to standard open surgery for the treatment of early cases and recently the feasibility of adequate D1+ dissection has been demonstrated also for the robot assisted technique. In case of AGC the debate on the extent of nodal dissection has been open for many decades. While D2 gastrectomy was performed as the standard procedure in eastern countries, mostly based on observational and retrospective studies, in the west the Medical Research Council(MRC), Dutch and Italian RCTs have been conducted to show a survival benefit of D2 over D1 with evidence based medicine. Unfortunately both the MRC and the Dutch trials failed to show a survival benefit after the D2 procedure, mostly due to the significant increase of postoperative morbidity and mortality, which was referred to splenopancreatectomy. Only 15 years after the conclusion of its accrual, the Dutch trial could report a significant decrease of recur-rence after D2 procedure. Recently the long term survival analysis of the Italian RCT could demonstrate a benefit for patients with positive nodes treated with D2 gastrectomy without splenopancreatectomy. As nowadays also in western countries D2 procedure can be done safely with pancreas preserving technique and without preventive splenectomy, it has been suggested in several national guidelines as the recommended procedure for patients with AGC. | Maurizio Degiuli Giovanni De Manzoni Alberto Di Leo Domenico D'Ugo Erica Galasso Daniele Marrelli Roberto Petrioli Karol Polom Franco Roviello Francesco Santullo Mario Morino | 2016 | World Journal of Gastroenterology2016，22，10： | 29 |
| 6 | Transarterial chemoembolization:Evidences from the literature and applications in hepatocellular carcinoma patients显示文摘Transarterial chemoembolization(TACE) is the current standard of care for patients with large or multinodular hepatocellular carcinoma(HCC), preserved liver function, absence of cancer-related symptoms and no evidence of vascular invasion or extrahepatic spread(i.e., those classified as intermediate stage according to the Barcelona Clinic Liver Cancer staging system). The rationale for TACE is that the intra-arterial injection of a chemotherapeutic drug such as doxorubicin or cisplatin followed by embolization of the blood vessel will result in a strong cytotoxic effect enhanced by ischemia. However, TACE is a very heterogeneous operative technique and varies in terms of chemotherapeutic agents, treatment devices and schedule. In order to overcome the major drawbacks of conventional TACE(c TACE), non-resorbable drug-eluting beads(DEBs) loaded with cytotoxic drugs have been developed. DEBs are able to slowly release the drug upon injection and increase the intensity and duration of ischemia while enhancing the drug delivery to the tumor. Unfortunately, despite the theoretical advantages of this new device and the promising results of the pivotal studies, definitive data in favor of its superiority over c TACE are still lacking. The recommendation for TACE as the standard-of-care for intermediate-stage HCC is based on the demonstration of improved survival compared with best supportive care or suboptimal therapies in a meta-analysis of six randomized controlled trials, but other therapeutic options(namely, surgery and radioembolization) proved competitive in selected subsets of intermediate HCC patients. Other potential fields of application of TACE in hepato-oncology are the pre-transplant setting(as downstaging/bridging treatment) and the early stage(in patients unsuitable to curative therapy). The potential of TACE in selectedadvanced patients with segmental portal vein thrombosis and preserved liver function deserves further reports. | Antonio Facciorusso Raffaele Licinio Nicola Muscatiello Alfredo Di Leo Michele Barone | 2015 | World Journal of Hepatology2015，7，16： | 25 |
| 7 | How antibiotic resistances could change Helicobacter pylori treatment:A matter of geography?显示文摘Therapeutic management of Helicobacter pylori(H.pylori)remains an unsolved issue.Indeed,no therapeutic regimen is able to cure the infection in all treated patients,and in many the infection persists despite the administration of several consecutive standard therapies.Although antibiotic resistance reports describe alarming results,the outcome of therapeutic regimens does not seem to parallel this scenario in most cases,since a successful performance is often reached in more than 80%of cases.However,the phenomenon of increasing antibiotic resistance is being closely studied,and the results show controversial aspects even in the same geographic area.For the continents of Europe,America,Asia,Africa,and Oceania,minimal and maximal values of resistance to the main antibiotics(clarithromycin,amoxicillin,metronidazole,and levofloxacin)feature wide ranges in different countries.The real enigma is therefore linked to the several different therapeutic regimens,which show results that often do not parallel the in vitro findings even in the same areas.A first aspect to be emphasized is that some regimens are limited by their use in very small geographic districts.Moreover,not all therapeutic trials have considered bacterial and host factors affecting the therapeutic outcome.The additional use of probiotics may help to reduce adverse events,but their therapeutic impact is doubtful.In conclusion,the'ideal therapy',paradoxically,appears to be a'utopia',despite the unprecedented volume of studies in the field and the real breakthrough in medical practice made by the discovery and treatment of H.pylori.The ample discrepancies observed in the different areas do not encourage the development of therapeutic guidelines that could be valid worldwide.On these bases,one of the main challenges for the future might be identifying a successful solution to overcome antibiotic resistances.In this context,geography must be considered a relevant matter. | Enzo Ierardi Floriana Giorgio Giuseppe Losurdo Alfredo Di Leo Mariabeatrice Principi | 2013 | World Journal of Gastroenterology2013，19，45： | 23 |
| 8 | Epidural anesthesia improves pancreatic perfusion and decreases the severity of acute pancreatitis显示文摘AIM: To study the safety of epidural anesthesia(EA),its effect on pancreatic perfusion and the outcome of patients with acute pancreatitis(AP).METHODS: From 2005 to August 2010,patients with predicted severe AP [Ranson score ≥ 2,C-reactive protein > 100 or necrosis on computed tomography(CT)] were prospectively randomized to either a group receiving EA or a control group treated by patientcontrolled intravenous analgesia. Pain management was evaluated in the two groups every eight hours using the visual analog pain scale(VAS). Parameters for clinical severity such as length of hospital stay,use of antibiotics,admission to the intensive care unit,radiological/clinical complications and the need for surgical necrosectomy including biochemical data were recorded. A CT scan using a perfusion protocol was performed on admission and at 72 h to evaluate pancreatic blood flow. A significant variation in blood flow was defined as a 20% difference in pancreatic perfusion between admission and 72 h and was measured in the head,body and tail of the pancreas.RESULTS: We enrolled 35 patients. Thirteen were randomized to the EA group and 22 to the control group. There were no differences in demographic characteristics between the two groups. The Balthazar radiological severity score on admission was higher in the EA group than in the control group(mean score 4.15 ± 2.54 vs 3.38 ± 1.75,respectively,P = 0.347) and the median Ranson scores were 3.4 and 2.7 respectively(P = NS). The median duration of EA was 5.7 d,and no complications of the epidural procedure were reported. An improvement in perfusion of the pancreas was observed in 13/30(43%) of measurements in the EA group vs 2/27(7%) in the control group(P = 0.0025). Necrosectomy was performed in 1/13 patients in the EA group vs 4/22 patients in the control group(P = 0.63). The VAS improved during the first ten days in the EA group compared to the control group(0.2 vs 2.33,P = 0.034 at 10 d). Length of stay and mortality were not statistically different between the 2 groups(26 d vs 30 d,P = 0.65,and 0% for both respectively).CONCLUSION: Our study demonstrates that EA increases arterial perfusion of the pancreas and improves the clinical outcome of patients with AP. | Samira M Sadowski Axel Andres Philippe Morel Eduardo Schiffer Jean-Louis Frossard Alexandra Platon Pierre-Alexandre Poletti Leo Bühler | 2015 | World Journal of Gastroenterology2015，21，43： | 21 |
| 9 | Intestinal microbiota: The explosive mixture at the origin of inflammatory bowel disease?显示文摘Inflammatory bowel diseases(IBDs), namely Crohn's disease and ulcerative colitis, are lifelong chronic disorders arising from interactions among genetic, immunological and environmental factors. Although the origin of IBDs is closely linked to immune response alterations, which governs most medical decision-making, recent findings suggest that gut microbiota may be involved in IBD pathogenesis. Epidemiologic evidence and several studies have shown that a dysregulation of gut microbiota(i.e., dysbiosis) may trigger the onset of intestinal disorders such as IBDs. Animal and human investigations focusing on the microbiota-IBD relationship have suggested an altered balance of the intestinal microbial population in the active phase of IBD. Rigorous microbiota typing could, therefore, soon become part of a complete phenotypic analysis of IBD patients. Moreover, individual susceptibility and environmental triggers such as nutrition, medications, age or smoking could modify bacterial strains in the bowel habitat. Pharmacological manipulation of bowel microbiota is somewhat controversial. The employment of antibiotics, probiotics, prebiotics and synbiotics has been widely addressed in theliterature worldwide, with the aim of obtaining positive results in a number of IBD patient settings, and determining the appropriate timing and modality of this intervention. Recently, novel treatments for IBDs, such as fecal microbiota transplantation, when accepted by patients, have shown promising results. Controlled studies are being designed. In the near future, new therapeutic strategies can be expected, with non-pathogenic or modified food organisms that can be genetically modified to exert anti-inflammatory properties. | Roberto Bringiotti Enzo Ierardi Rosa Lovero Giuseppe Losurdo Alfredo Di Leo Mariabeatrice Principi | 2014 | World Journal of Gastrointestinal Pathophysiology2014，5，4： | 20 |
| 10 | 5-Methylcytosine RNA Methylation in Arabidopsis Thaliana显示文摘5-Methylcytosine (m 5 C ) 是描绘得好的 DNA 修正,并且主要也在初核质和优核质在丰富的非编码的 RNA 被报导。然而,分发和 m 5 在植物 mRNAs 的 C 仍然保持大部分未知。这里,我们报导 RNA m 5 在由使用 m 5 C RNA immunoprecipitation 由一条深定序的途径列在后面(m 5 C-RIP-seq ) 。LC-MS/MS 和点污点分析揭示 m 5 在各种各样的纸巾并且在不同发展阶段的 C mRNA 修正。m 5 C-RIP-seq 分析识别了 6045 m 5 在 4465 的 C 山峰在年轻幼苗表示了基因。我们发现那 m 5 C 在编码序列,二座山峰在开始 codons 以后并且在站 codons 前立即定位了被充实,并且随低翻译与 mRNAs 被联系活动。我们进一步表明了那 RNA (cytosine-5 )-methyltransferase,tRNA 特定的 methyltransferase 4B (TRM4B ) ,展览 m 5 C RNA methyltransferase 活动。在 TRM4B 的变化在根开发和减少的 m 5 C 山峰。TRM4B 影响涉及根开发的基因的抄本层次,它断然与他们的 mRNA 稳定性和 m 5 C 层次。我们的结果建议那 m 5 在 mRNA 的 C 是新 epitranscriptome 标记 inArabidopsis,并且这修正的那条规定是基因的不可分的部分规章的网络位于 \O 下面植物开发。 | Xuean Cui Zhe Liang Lisha Shen Qian Zhang Shengjie Bao Yuke Geng Bin Zhang Vonny Leo Leah A. Vardy Tiegang Lu Xiaofeng Gu Hao Yu | 2017 | Molecular Plant2017，10，11： | 19 |
| 11 | 变荷载下饱和软黏土一维大应变固结解析理论显示文摘基于软黏土一维非线性大应变固结基本理论,建立了能考虑荷载变化、土层自重等因素影响的拉格朗日坐标下以超静孔压u为变量的一维大应变固结控制方程,并通过对土体压缩性和渗透性的假定获得了方程的解析解。基于此解,分析了单级等速加荷条件下软黏土一维大应变固结性状。从中可见,大应变固结过程中土体变形的发展要快于超静孔压的消散;荷载增大,超静孔压消散趋慢;加荷速率越大,土体固结越快;考虑土层自重影响时孔隙比的分布更为合理。此外,本文的解析解也可用于验证各种大应变固结数值解法的正确性。 | 谢康和 郑辉 C J Leo | 2003 | 水利学报2003，34，10： | 19 |
| 12 | Probiotic monotherapy and Helicobacter pylori eradication: A systematic review with pooled-data analysis显示文摘AIM To define probiotic monotherapy effect on Helicobacter pylori(H. pylori) status by performing a systematic review.METHODS Methods of analysis and inclusion criteria were based on PRISMA recommendations. Relevant publications were identified by searching Pub Med, MEDLINE, Science Direct, and EMBASE. The end-point was to estimate eradication rate and urea breath test delta value before and after probiotic monotherapy across all studies and, overall, with a pooled data analysis. Adverse events of probiotic therapy were evaluated. The data were expressed as proportions/percentages, and 95%CIs were calculated. For continuous variables, we evaluated the weighted mean difference. Odd ratios(ORs) were calculated according to the Peto method for the comparison of eradication rates between probiotics and placebo.RESULTS Eleven studies were selected. Probiotics eradicated H. pylori in 50 out of 403 cases. The mean weighted eradication rate was 14%(95%CI: 2%-25%, P =0.02). Lactobacilli eradicated the bacterium in 30 out of 235 patients, with a mean weighted rate of 16%(95%CI: 1%-31%). Saccharomyces boulardii achieved eradication in 6 out of 63 patients, with a pooled eradication rate of 12%(95%CI: 0%-29%). Multistrain combinations were effective in 14 out of 105 patients, with a pooled eradication rate of 14%(95%CI: 0%-43%). In the comparison of probiotics vs placebo, we found an OR of 7.91 in favor of probiotics(95%CI: 2.97-21.05, P < 0.001). Probiotics induced a mean reduction in delta values higher than placebo(8.61% with a 95%CI: 5.88-11.34, vs 0.19% for placebo, P < 0.001). Finally, no significant difference in adverse events was found between probiotics and placebo(OR = 1, 95%CI: 0.06-18.08).CONCLUSION Probiotics alone show a minimal effect on H. pylori clearance, thus suggesting a likely direct role. | Giuseppe Losurdo Rossella Cubisino Michele Barone Mariabeatrice Principi Gioacchino Leandro Enzo Ierardi Alfredo Di Leo | 2018 | World Journal of Gastroenterology2018，24，1： | 18 |
| 13 | 土壤中全氟和多氟烷基化合物的污染现状及环境行为显示文摘全氟和多氟烷基化合物(perfluoroalkyl and polyfluoroalkyl substances,PFASs)是一类新兴持久性有机污染物.土壤中PFASs可以通过淋溶作用进入地下水影响水质安全,或者通过陆生食物链的传递和生物放大作用危害生态系统和人类健康,有关土壤中PFASs的赋存状况、浓度水平与行为机制的研究已经成为环境化学领域的热点之一.目前土壤中可以准确测定的PFASs在含氟化合物总量中的占比不到1%,含量为ng g水平.我国相关研究主要集中在东部及氟化工厂周边地区,其组分以全氟辛烷磺酸(Perfluorooctane sulfonic acid,PFOS)和全氟辛酸(Perfluorooctanoic acid,PFOA)等长链PFASs为主.不同类型土壤中PFASs的赋存特征主要受到物质种类与土壤理化性质及周边人类活动的影响.除了含氟化学品生产和使用过程中的直接释放和大气传输以外,PFASs前体物在土壤环境中的转化也是其重要来源.吸附-解吸是PFASs在土壤中的主要归趋方式,化合物碳链长度及官能团种类、土壤理化性质和生物种类等因素都会影响其在土壤中的迁移转化和富集能力.鉴于目前的研究现状,需要进一步优化土壤中PFASs的提取和分析方法,关注新型PFASs在土壤中的变化趋势及行为机制,开展土壤中PFASs的生物可给性和生物可利用性研究,进一步评估PFASs的生态与人体健康风险. | 陈诗艳 仇雁翎 朱志良 Leo WYYeung | 2021 | 环境科学研究2021，34，2： | 17 |
| 14 | Intraoperative cell salvage with autologous transfusion in liver transplantation显示文摘Liver transplant(LT) is the primary treatment for patients with end-stage liver disease. About 25000 LTs are performed annually in the world. The potential for intraoperative bleeding is quite variable. However, massive bleeding is common and requires blood transfusion. Allogeneic blood transfusion has an immunosuppressive effect and an impact on recipient survival, in addition to the risk of transmission of viral infections and transfusion errors, among others.Techniques to prevent excessive bleeding or to use autologous blood have been proposed to minimize the negative effects of allogeneic blood transfusion.Intraoperative reinfusion of autologous blood is possible through previous selfdonation or blood collected during the operation. However, LT does not normally allow autologous transfusion by prior self-donation. Hence, using autologous blood collected intraoperatively is the most feasible option. The use of intraoperative blood salvage autotransfusion(IBSA) minimizes the perioperative use of allogeneic blood, preventing negative transfusion effects without negatively impacting other clinical outcomes. The use of IBSA in patients with cancer is still a matter of debate due to the theoretical risk of reinfusion of tumor cells. However, studies have demonstrated the safety of IBSA in several surgical procedures, including LT for hepatocellular carcinoma. Considering the literature available to date, we can state that IBSA should be routinely used in LT, both in patients with cancer and in patients with benign diseases. | Marcelo A Pinto Marcio F Chedid Leo Sekine Andre P Schmidt Rodrigo P Capra Carolina Prediger Jo?o E Prediger Tomaz JM Grezzana-Filho Cleber RP Kruel | 2019 | World Journal of Gastrointestinal Surgery2019，11，1： | 16 |
| 15 | Optimizing proton pump inhibitors in Helicobacter pylori treatment:Old and new tricks to improve effectiveness显示文摘The survival and replication cycle of Helicobacter pylori(H.pylori)is strictly dependant on intragastric pH,since H.pylori enters replicative phase at an almost neutral pH(6-7),while at acid pH(3-6)it turns into its coccoid form,which is resistant to antibiotics.On these bases,it is crucial to increase intragastric pH by proton pump inhibitors(PPIs)when an antibiotic-based eradicating therapy needs to be administered.Therefore,several tricks need to be used to optimize eradication rate of different regimens.The administration of the highest dose as possible of PPI,by doubling or increasing the number of pills/day,has shown to be able to improve therapeutic outcome and has often proposed in rescue therapies,even if specific trials have not been performed.A pre-treatment with PPI before starting antibiotics does not seem to be effective,therefore it is discouraged.However,the choice of PPI molecule could have a certain weight,since second-generation substances(esomeprazole,rabeprazole)are likely more effective than those of first generation(omeprazole,lansoprazole).A possible explanation is due to their metabolism,which has been proven to be less dependent on cytochrome P450(CYP)2C19 genetic variables.Finally,vonoprazan,a competitive inhibitor of H+/K+-ATPase present on luminal membrane of gastric parietal cells has shown the highest efficacy,due to both its highest acid inhibition power and rapid pharmacologic effect.However current data come only from Eastern Asia,therefore its strong power needs to be confirmed outside this geographic area in Western countries as well as related to the local different antibiotic resistance rates. | Enzo Ierardi Giuseppe Losurdo Rosa Federica La Fortezza Mariabeatrice Principi Michele Barone Alfredo Di Leo | 2019 | World Journal of Gastroenterology2019，25，34： | 15 |
| 16 | DIFFUSION COUPLE BETWEEN HIGHSTRENGTH WEAR-RESISTING ALUMINUM BRONZE AND MACHINING TOOLS MATERIALS显示文摘INTRODUCTIONAluminumbronzeisanimportantengineeringmaterial.Itsexcelentphysical,mechanical,anticorosionandwearresistingprop... | Li, Yuanyuan Zhang, Datung Ngai Tungwai, Leo Xia, Wei Long, Yan | 1999 | 中国有色金属学会会刊:英文版1999，9，1： | 14 |
| 17 | Effect of Die Wall Lubrication on Warm Compaction Powder Metallurgy显示文摘Die wall lubrication was applied on warm compaction powder metallurgy in hope to reduce the concentration level of the admixed lubricant since lubricant is harmful to the mechanical property of the sintered materials. Iron-based samples were prepared by die wall lubricated warm compaction at 135 ℃ and 175 ℃, using polytetrafluoroethylene (PTFE) emulsion as die wall lubricant. A compacting pressure of 700 MPa and 550 MPa were used. The admixed lubricant concentration ranging from 0 to 0.6 wt.% was used in this study. Compared with non-die wall lubricated samples, the die wall lubricated samples have higher green densities. Results show that in addition to the decrease in ejection forces, green density of the compacts increased linearly with the decrease in admixed lubricant content. Mechanical property of the sintered compacts increase sharply when the admixed lubricant concentration reduced to 0.125 wt.% or less. Ejection force data indicated that samples with die wall lubrication show lower ejection forces when compared with samples without die wall lubrication. No scoring was observed in all experiments even for samples contain no admixed lubricant. Our results indicated that under experimental condition used in this study, no matter at which compaction pressure, compaction temperature, graphite and lubricant contents in the powder the die wall lubricated warm compaction would give the highest green density and lowest ejection force. It can be concluded that combination of die wall lubrication and warm compaction can provide P/M products with higher density and better quality. It is a feasible way to produce high performance P/M parts if suitable die wall lubrication system was applied. | LI Yuan-yuan, NGAI Tungwai Leo, ZHANG Da-tong, LONG Yan, XIA Wei (College of Mechanical Engineering, South China University of Technology, Guangzhou 510640, China) | 2002 | 厦门大学学报(自然科学版)2002，41，S1： | 13 |
| 18 | Regulation of the SQUAMOSA PROMOTER-BINDING PROTEIN-LIKE genes/microRNA 156 Module by the Homeodomain Proteins PENNYWISE and POUND-FOOLISH in Arabidopsis显示文摘开花期的形态学被调整花说明的时间、空间的事件部分地调整。在 Arabidopsis,一条内长的 flowering 时间小径由 SQUAMOSA 倡导者绑定的一个子集调停了像蛋白质(系统程序设计语言) 包括 SPL3, SPL4,和 SPL5,抄写因素工作由激活花的分裂组织身份基因指定花。在射击开发期间, SPL3, SPL4,和 SPL5 被 microRNA156 (miR156 ) post-transcriptionally 调整。光周期调整了 florigenic 信号, FLOWERING 地点 T (英尺) ,支持花的正式就职,部分地由激活 SPL3, SPL4,和 SPL5。接着,这些系统程序设计语言与英尺同时工作指定花分裂组织。二相关象 BELL1 一样 homeobox 基因 PENNYWISE (PNY ) 并且省小钱吃大亏(PNF ) 在射击表示了顶端的分裂组织绝对为花的分裂组织的说明被要求。基因研究证明英尺的花的说明功能取决于 PNY 和 PNF;然而,在这些 homeodomain 蛋白质和系统程序设计语言之间的相互影响不被知道。在这张手稿,我们证明 SPL3, SPL4,和 SPL5 的花的正式就职是的 photoperiodic 依赖于 PNY 和 PNF。进一步, PNY 和 PNF 也由否定地调整 miR156 控制 SPL3, SPL4,和 SPL5 表示。最后, SPL4 的宫外的表示部分救 pny pnf non-flower-producing 显型,当在 pny pnf 植物的 SPL3 或 SPL5 的 overexpression 是不能的恢复花说明时。这些结果建议那:(1 ) SPL3, SPL4,和 SPL5 功能依赖于 PNY 和 PNF,或(2 ) 多重系统程序设计语言的表示在 pny pnf 植物为花的说明被要求。 | Shruti Lal Leo Bryan Pacis Harley M.S. Smith | 2011 | Molecular Plant2011，4，6： | 13 |
| 19 | Random Forests显示文摘 | Leo Breiman | 2001 | Machine Learning2001，，1： | 13 |
| 20 | Perfluorooctane sulfonate(PFOS) and related fluorochemicals in chicken egg in China显示文摘The ubiquitous occurrence of perfluorinated compounds(PFCs) in environmental samples has drawn much attention.Recent human exposure studies found relatively high perfluorooctane sulfonate(PFOS) concentrations in blood samples from several cities in China when compared with other countries.The objectives of the present study were:(1) to measure PFC concentrations and compositions in chicken egg samples from local markets in China;and(2) to conduct a preliminary human health risk assessment of egg consumption.Eight pooled egg samples from eight locations were analyzed for 11 PFCs.The results showed that close to 100% of the PFOS in the egg was distributed in egg yolk and PFOS was not detected in egg white(<0.08 ng/g wet weight,w/w).Of the perfluoroalkylsulfonates,only PFOS was detected in all egg samples,while of the perfluoroalkylcarboxylates,perfluoroundecanoic acid(PFUnDA) was detected in all samples,followed by perfluorooctanoate(PFOA)(75% occurrence) and perfluorodecanoic acid(PFDA)(50% occurrence).PFOS concentrations in egg ranged from 45.0 to 86.9 ng/g w/w.The results suggested that current concentrations of PFOS in domestic chicken eggs are unlikely to cause immediate harm to Chinese populations. | WANG Yuan YEUNG Leo Wai Yin YAMASHITA Nobuyoshi TANIYASU Sachi SO Man Ka Margaret B. MURPHY LAM Paul Kwan Sing | 2008 | Chinese Science Bulletin2008，53，4： | 13 |
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