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| 1 | The reg4 gene,am-plifled in the early stages of pancreatic cancer development,is apromising therapeutic target显示文摘 | Legoffic A Calvo E Cano C | 2009 | PLoS One2009，4，10： | 1 |
| 2 | Polyaniline layer for iron protection in sulfate medium显示文摘 | BERNARD M C HUGOT- LEGOFF A JOIRET S | 1999 | Synthetic Metals1999，102，1： | 1 |
| 3 | Determination of reduced sulfur compounds by high-performance liquid chromatography in hydrothermal sea water and body fluids from Riftia pachyptila显示文摘 | GIkU C SAR/kADIN PM LEGOFF H | 1998 | Analyst1998，123，6： | 1 |
| 4 | The Threat of Peste des Petits Ruminants:Progress in Vaccine Development for Disease Control显示文摘 | DIALLO A MINET C LEGOFF C | 2007 | Vaccine2007，25，30： | 1 |
| 5 | Development of a dual recombinant vaccine to protect small ruminants against peste des petits ruminants virus and capripoxvims infections显示文摘 | Berhe G Minet C LeGoff C | 2003 | Virol2003，77，2： | 1 |
| 6 | The reg4 gene, amplified in the early stages of pancreatic cancer development, is a promising therapeutic target显示文摘 | Legoffic A Calvo E Cano C | 2009 | PLoS One2009，4，10： | 1 |
| 7 | Evaluation of immunoaffinity chromatography as a replacement for organic solvent clean-up of plant extracts for the determination of triazine herbicides by liquid chromatography显示文摘 | LAWRENCE J F MENARD C HENNION M PICHON V LEGOFFIC F DURAND N | 1996 | J Chromatogr: A1996，752，12： | 1 |
| 8 | Determination of reduced sulfur compounds by high-performance liquid chromatography in hydrothermal seawater and body fluids from Riftia pachyptila显示文摘 | Gru C Sarradin P M Legoff H | 1998 | Analyst1998，123，6： | 1 |
| 9 | Patterns of herpes simplex vi-rus shedding over 1 month and the impact of acyclovir and HIV inHSV-2-seropositive women in Tanzania显示文摘 | Tanton C Weiss H A Legoff J | 2011 | Sex Transm Infect2011，87，5： | 1 |
| 10 | Development of a dual recombinant vaccine to protect small ruminants against peste-des-petits-ruminants virus and capripoxvirus infections显示文摘 | Berhe G Minet C Legoff C | 2003 | J Virol2003，77，2： | 1 |
| 11 | The reg4 gene,amplified in the early stages of pancreatic cancer development,is a promising therapeutic target显示文摘 | Legoffic A Calvo E Cano C | 2009 | PLoS One2009，4，10： | 1 |
| 12 | Influence of storage temperature on the stability of HIV1 RNA and HSV2 DNA in cervicovaginal secretions collect ed by vaginal washing显示文摘 | Legoff J Tanton C Lecerf M | 2006 | Journal of Virological Methods2006，138，12： | 1 |
| 13 | Polyaniline layer for iron protection in sulfate medium 显示文摘 | BERNARD M C HUGOT - LEGOFF A JOIRET S | 1999 | Synthetic Metal1999，，102： | 1 |
| 14 | Evalution of indirect fluo- rescent antibody test(IFAT)for the diagnosis and screening of lumpy skin disease using Bayesian method显示文摘 | Gari G Biteau C F Legoff C | 2008 | Vet Microbiol2008，129，34： | 1 |
| 15 | Early impairment of CD8 + T cells immune response against Epstein - Barr virus (EBV) antigens associated with high level of circulating mononuclear EBV DNA load in HIV infection 显示文摘 | Legoff J Amiel C Calisonni O | 2004 | J Clin Immunol2004，24，2： | 1 |
| 16 | Evaluation of indirect fluorescent antibody test (IFAT) for the diagnosis and screening of lumpy skin disease using Bayesian method 显示文摘 | Gari G Biteau-Coroller F LeGoff C | 2008 | Veterinary Microbiology2008，129，： | 1 |
| 17 | An adaptive microscope for the imaging of biological surfaces显示文摘Scanning fluorescence microscopes are now able to image large biological samples at high spatial and temporal resolution.This comes at the expense of an increased light dose which is detrimental to fluorophore stability and cell physiology.To highly reduce the light dose,we designed an adaptive scanning fluorescence microscope with a scanning scheme optimized for the unsupervised imaging of cell sheets,which underly the shape of many embryos and organs.The surface of the tissue is first delineated from the acquisition of a very small subset(~0.1%)of sample space,using a robust estimation strategy.Two alternative scanning strategies are then proposed to image the tissue with an improved photon budget,without loss in resolution.The first strategy consists in scanning only a thin shell around the estimated surface of interest,allowing high reduction of light dose when the tissue is curved.The second strategy applies when structures of interest lie at the cell periphery(e.g.adherens junctions).An iterative approach is then used to propagate scanning along cell contours.We demonstrate the benefit of our approach imaging live epithelia from Drosophila melanogaster.On the examples shown,both approaches yield more than a 20-fold reduction in light dose-and up to more than 80-fold-compared to a full scan of the volume.These smart-scanning strategies can be easily implemented on most scanning fluorescent imaging modality.The dramatic reduction in light exposure of the sample should allow prolonged imaging of the live processes under investigation. | Faris Abouakil Huicheng Meng Marie-Anne Burcklen Herve Rigneault Frederic Galland Loïc LeGoff | 2021 | Light(Science & Applications)2021，10，11： | 0 |
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