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| 1 | Lean techniques for the improvement of patients' flow in emergency department显示文摘BACKGROUND: Emergency departments(EDs) face problems with overcrowding, access block, cost containment, and increasing demand from patients. In order to resolve these problems, there is rising interest to an approach called 'lean' management. This study aims to(1) evaluate the current patient flow in ED,(2) to identify and eliminate the non-valued added process, and(3) to modify the existing process.METHODS: It was a quantitative, pre- and post-lean design study with a series of lean management work implemented to improve the admission and blood result waiting time. These included structured re-design process, priority admission triage(PAT) program, enhanced communication with medical department, and use of new high sensitivity troponin-T(hsTnT) blood test. Triage waiting time, consultation waiting time, blood result time, admission waiting time, total processing time and ED length of stay were compared.RESULTS: Among all the processes carried out in ED, the most time consuming processes were to wait for an admission bed(38.24 minutes; SD 66.35) and blood testing result(mean 52.73 minutes, SD 24.03). The triage waiting time and end waiting time for consultation were significantly decreased. The admission waiting time of emergency medical ward(EMW) was significantly decreased from 54.76 minutes to 24.45 minutes after implementation of PAT program(P<0.05).CONCLUSION: The application of lean management can improve the patient flow in ED. Acquiescence to the principle of lean is crucial to enhance high quality emergency care and patient satisfaction. | HY Chan SM Lo LLY Lee WYL Lo WC Yu YF Wu ST Ho RSD Yeung JTS Chan | 2014 | World Journal of Emergency Medicine2014，5，1： | 6 |
| 2 | Derivation of hypermethylated pluripotent embryonic stem cells with high potency显示文摘天真的 hypomethylated 胚胎的 pluripotent 干细胞(转换字符) 离胚囊的 preimplantation epiblast 发展地最靠近,与潜力到贡献所有胚胎的纸巾和 germline,除了在妄想的胚胎的胚胎外的纸巾。由对比,类似于 postimplantation epiblast 的 epiblast 干细胞(EpiSCs ) 是相对更多的 methylated 和表演为 chimerism 的一个有限潜力。第一次,这里,我们在 pluripotent 房间以外发展地揭示先进 pluripotent 干细胞(ASC ) ,它是在内部房间团中,但是与更高的力量比 EpiSCs。因此,单个 ASC 在怪物很高效地作出贡献到胎儿, germline,蛋黄囊和胎盘的迷宫。因为他们是,发展地,更多进展了, ASC 不贡献 trophoblast。ASC 在与 Activin A 和基本成纤维细胞生长因素补充的化学上定义的媒介在二个步骤从胚囊被导出,在包含 ActA, BMP4, CHIR99021 和白血病的 ABCL 媒介由 culturing 列在后面禁止的因素。尤其是, ASC 与天真的 pluripotency 基因,以及 mesodermal 的表示展出不同 transcriptome 体的基因;Eomes,时代, Tdgf1, Evx1, hand1, Wnt5a 和不同重复元素。到 ASC 的确定的转换字符的变换也是可完成的。重要地, ASC 作为与 hypomethylated 相比展出稳定的 hypermethylated epigenome 和主要未经触动的印记胚囊和天真的转换字符的内部房间质量。ASC 的性质建议他们以在 pluripotency 的天真、告知的状态之间的一个中间的细胞的状态代表房间。 | Siqin Bao Walfred WC Tang Baojiang Wu Shinseog Kim Jingyun Li Lin Li Toshihiro Kobayashi Caroline Lee Yanglin Chen Mengyi Wei Shudong Li Sabine Dietmann Fuchou Tang Xihe Li | 2018 | Cell Research2018，28，1： | 4 |
| 3 | Vaccination of advanced hepatocellclar carcinoma patients with tumor lysate-pulsed dendritic cells : a clinical trial显示文摘 | Lee WC Wang HC Hung C F | 2006 | J Immunother2006，28，5： | 1 |
| 4 | Initially unrecognized dementia in a young man wihe neurosyphilis 显示文摘 | Lee CH Lin wc Lu CH | 2009 | Neurolodist2009，15，： | 1 |
| 5 | Design of monolimb using finite element modelling and statistics- based Taguchi method显示文摘 | Lee WC Zhang M | 2005 | Clinical biomechanics2005，20，7： | 1 |
| 6 | A transforming KIF5B and RKTgene fusion in lung adenocarcinoma revealed from whole-genome andtranscrip-tome sequencing显示文摘 | Ju YS Lee WC Shin JY | 2012 | Genome Res2012，22，3： | 1 |
| 7 | Fluorinated graphene for promoting neuro-induction of stem cells 显示文摘 | Wang Y Lee WC Mauga KK | 2012 | Adv Mater2012，24，31： | 1 |
| 8 | Lipid peroxidation dysregulaion in ischemic stroke:plasma 4-HNE as a potential biomarker显示文摘 | Lee WC Wong HY Chai YY | 2012 | Biochem Biophys Res Commun2012，425，4： | 1 |
| 9 | Adenosquamous/squamous cell carcinoma of the gallbladder 显示文摘 | Chan KM Yu MC Lee WC | 2007 | J Surg Oncol2007，95，2： | 1 |
| 10 | Extended plasticity of visual cortex in dark-reared animals may result from prolonged expression of cpg15-like genes显示文摘 | Lee WC Nedivi E | 2002 | J Neurosci2002，22，5： | 1 |
| 11 | Spontaneous tumour rupture and prognosis in patients with hepatocellular carcinoma显示文摘 | Yeh CN Lee WC Jeng LB | 2002 | Br J Surg2002，89，9： | 1 |
| 12 | Elevation of plasminogen activators in cerebrospinal fluid of mice with eosinophilic meningitis caused by Angiostrongylus cantonensis 显示文摘 | Roger FH Tu WC Lee HH | 2004 | Int J Parasitol2004，34，： | 1 |
| 13 | Etiologic study of ischemic stroke in young taiwan显示文摘 | Lee TH Hsu WC Chen CJ | 2002 | Stroke2002，，： | 1 |
| 14 | Risk factors for postencephalitic epilepsy in children;a hospital-based study in Taiwan显示文摘 | Lee WT Yu TW Chang WC | 2007 | Eur J Paediatr Neurol2007，11，5： | 1 |
| 15 | Availability of fine needle aspirates for the assessment of HER2 gene amplification in invasive breast cancer patients 显示文摘 | Lee JW Noh WC Kim MS | 2008 | Korean J lab Med2008，28，5： | 1 |
| 16 | Fas-mediated acute lung injury requires Fas expression on nonmyeloid cells of the lung显示文摘 | Matute-Bello G Lee JS Liles WC | | 0，，06： | 1 |
| 17 | Etiologic study of young ischemic stroke in Taiwan显示文摘 | Lee TH Hsu WC Chen CJ | 2002 | Stroke2002，33，： | 1 |
| 18 | A transforming KIF5B and RET gene fusion in lung adenocarcinoma revealed from whole-genome and transcriptome sequencing显示文摘 | Ju YS Lee WC Shin JY | 2012 | Genome Res2012，22，3： | 1 |
| 19 | Antionxiative flavonoids from the leaves ofMorus alba显示文摘 | Kim Sy Gao J J Lee Wc | 1999 | Arch Pharm Res1999，22，1： | 1 |
| 20 | Foodborne illness outbreaks in Korea and Japan studied retrospectively显示文摘 | Lee MJ Kim JS | 2001 | J Food Prot2001，64，6： | 1 |
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