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| 1 | 抑郁症的非药物治疗:系统性综述与证据图显示文摘背景抑郁症非药物治疗的疗效比较目前仍然不清楚。方法我们对一些系统性综述作了概述,回顾了随机对照试验(RCT),比较抑郁症非药物治疗的有效性和认知行为治疗(CBT)。对多个电子数据库在2016年2月之前发表的所有文献进行了检索,不限制语言。成对的评阅人进行资料纳入、数据提炼并评估偏倚的风险。在适用的时候进行了荟萃分析。结果我们收录了367项RCT,纳入了约2000名患者,进行了11种治疗,导出17项独立的头对头比较。通过标准化的量表评估,发现CBT、自然疗法、行为干预与躯体活动干预可以降低抑郁的严重程度。然而,这些非药物干预的相对疗效仍然缺乏。这些干预对临床缓解和复发的效果不清楚。CBT的发生率比抗抑郁药物更低。局限性由于证据缺乏一致性、证据不清或偏倚风险高,导致证据的质量只是低到中等,限制了我们研究结果的可信度。结论抑郁症的非药物治疗能减少抑郁症状,在轻度到重度抑郁症患者中,应当合并抗抑郁药物治疗,一同进行。对于非药物治疗的选择,应当根据患者的价值观、偏好、临床和社会因素来与患者共同作出决定。 | Wigdan H Farah Mouaz Alsawas Maria Mainou Fares Alahdab Magdoleen H Farah Ahmed T Ahmed Essa A Mohamed Jehad Almasri Michael R Gionfriddo Ana Castaneda-Guarderas Khaled Mohammed Zhen Wang Noor Asi Craig N Sawchuk Mark D Williams Larry J Prokop M Hassan Murad Annie LeBlanc | 2017 | 英国医学杂志中文版2017，20，11： | 2 |
| 2 | Evaluation of national and global LAI products derived from optical remote sensing instruments over Canada显示文摘 | Abuelgasim A A Fernandes R A Leblanc S G | 2006 | IEEE Transactions on Geoscience and Remote Sensing2006，44，7： | 1 |
| 3 | Apo2L/TRAIL and its death and decoy recptors显示文摘 | LeBlanc HN Ashkenazi A | 2003 | Cell Death Differ2003，10，： | 1 |
| 4 | Thephytomining and environmental significance of hyperaccumulation of thallium by Iberis intermedia from southern France显示文摘 | LEBLANC M PETIT D DERAM A | 1999 | Economic Geology1999，94，1： | 1 |
| 5 | Proteolysis associ- ated with insulin resistance in cystic fibrosis 显示文摘 | Hardin DS LeBlanc A Lukenbaugh S | 1998 | Pediatrics1998，101，31： | 1 |
| 6 | Active Video Games and Health Indicators in Children and Youth: A Systematic Review 显示文摘 | LeBlanc A Chaput J Tremblay M | 2013 | Plos ONE2013，，6： | 1 |
| 7 | Resistance exercise as a countermeasure to disuse-induced bone loss 显示文摘 | SHACKELFORD L C LEBLANC A D DRISCOLL T B | 2004 | J Appl Physiol2004，97，： | 1 |
| 8 | Polypropylene degra- dation : Theoretical and experimental investigations 显示文摘 | Bertin D Leblanc M Marque S R A | 2010 | Polym Degrad Stab2010，95，5： | 1 |
| 9 | Randomizedphase IH clinical trial designs for targeted agents显示文摘 | Hoering A Leblanc M Crowley JJ | 2008 | Clin Cancer Res2008，14，14： | 1 |
| 10 | Monitoring and maintaining the water clarity of salinity gradient solar ponds显示文摘 | Malik N Date A Leblanc J etal | 2011 | Solar Energy2011，85，11： | 1 |
| 11 | Gener- ation of a restriction fragment length polymorphism linkage map for Toxoplasma gondii 显示文摘 | Sibley L D Leblanc A J Pfefferkorn E R | 1992 | Genetics1992，132，4： | 1 |
| 12 | Systematic review of the health benefits of physical activity and fitness in school-aged children and youth 显示文摘 | JANSSEN I LEBLANC A G | 2010 | Int J Behav Nut Phys Act2010，7，： | 1 |
| 13 | Apo2L/TRAIL and its death and decoy receptors 显示文摘 | LeBlanc HN Ashkenazi A | 2003 | Cell Death Differ2003，10，1： | 1 |
| 14 | Selective and protracted ap- optosis in human primary neurons microinjected with active caspase-3 ,-6,-7, and-8 显示文摘 | Zhang Y Goodyer C LeBlanc A | 2000 | J Neurosci2000，20，22： | 1 |
| 15 | Biotransformation and disposition of testosterone in the eastern mud snail llyanassa obsoleta 显示文摘 | Gooding M P LeBlanc G A 2001 | 2001 | Gen Comp Endocrinol2001，122，： | 1 |
| 16 | Effects of endocrine- active chemicals on the development of sex characteristics of Daphnia magna 显示文摘 | Olmstead A W LeBlanc G A | 2000 | Environmental Toxicology and Chemistry2000，19，8： | 1 |
| 17 | Reduction of non-digestible oligosaccharidcs in soymilk:application of engineered lactic acid bacteria that produce a-galaetosidase显示文摘 | LEBLANC J G SILVESTRONI A CONNKS C | 2004 | Genetics and Molecular Research2004，3，3： | 1 |
| 18 | Effect of endocrine-active chemicals on the development of sex characteristics of Daphnia magna显示文摘 | Olmstead A W LeBlanc G G | 2000 | Environ Toxicol Chem2000，19，： | 1 |
| 19 | Reduction of α -galactooligosaccharides in soyamilk by Lactobacillus fermentum CRL722:in vitro and in vivo evaluation of fermented soyamilk显示文摘 | J G LeBlanc M S Garro A Silvestroni | 2004 | Journal of Applied Microbiology2004，97，： | 1 |
| 20 | Changes in interverte-bral disc cross-sectional area with bed rest and space flight显示文摘 | LeBlanc A D Evans H J Schneider V S | 1994 | Spine(Phila Pa 1976)1994，19，7： | 1 |
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