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| 1 | 《2013年全球乳房健康共识指南》解读--医院-社区一体化的延续性护理在乳腺癌生存者照护中的重要作用显示文摘乳腺癌发病率在中国呈快速上升趋势,同时其又是可以治愈的疾病,带癌生存者逐年增多;因此,医院-社区一体化的延续性护理势在必行。本文对《2013年全球乳房健康共识指南——中、低等收入国家乳腺癌生存者治疗期后的支持性护理》的内容进行解读,思考医院-社区一体化延续性护理的优势与提供者,介绍指南中专家根据资源分配情况建议相应的护理措施,并且分析我国目前开展医院-社区一体化延续性护理的障碍,旨在为我国护理工作者进行乳腺癌延续性护理提供科学依据。 | 郭奕嫱 李惠平 Soon Lean Keng Azlina Yusuf 雷慧 辛小林 | 2015 | 中国全科医学2015，18，6： | 32 |
| 2 | New advances on glial activation in health and disease显示文摘In addition to being the support cells of the central nervous system(CNS), astrocytes are now recognized as active players in the regulation of synaptic function, neural repair, and CNS immunity. Astrocytes are among the most structurally complex cells in the brain, and activation of these cells has been shown in a wide spectrum of CNS injuries and diseases. Over the past decade, research has begun to elucidate the role of astrocyte activation and changes in astrocyte morphology in the progression of neural pathologies, which has led to glial-specific interventions for drug development. Future therapies for CNS infection, injury,and neurodegenerative disease are now aimed at targeting astrocyte responses to such insults including astrocyte activation, astrogliosis and other morphological changes, and innate and adaptive immune responses. | Kim Mai Lee Andrew G Mac Lean | 2015 | World Journal of Virology2015，4，2： | 13 |
| 3 | Characterization of Air Pollution in Urban Areas of Yangtze River Delta,China显示文摘The hallmark of development in the Yangtze River Delta(YRD) of East China has been sprawling urbanization. However, air pollution is a significant problem in these urban areas. In this paper, we investigated and analyzed the air pollution index(API) in four cities(Shanghai, Nanjing, Hangzhou and Ningbo) in the YRD from 2001 to 2012. We attempted to empirically examine the relationship between meteorological factors and air quality in the urban areas of the YRD. According to the monitoring data, the API in Shanghai, Nanjing, Hangzhou slightly declined and that in Ningbo increased over the study period. We analyzed the inter-annual, seasonal, and monthly variations of API, from which we found that the air quality had different temporal changes in the four cities. It was indicated that air quality was poor in winter and spring and best in summer. Furthermore, different weather conditions affected air quality level. The wind direction was considered as an important and influential factor to air pollution, which has an impact on the accumulating or cleaning processes of pollutants. The air quality was influenced by the different wind directions that varied with seasons and cities. | CHEN Tan DENG Shulin GAO Yu QU Lean LI Manchun CHEN Dong | 2017 | Chinese Geographical Science2017，27，5： | 7 |
| 4 | FORECASTING CHINA'S FOREIGN TRADE VOLUME WITH A KERNEL-BASED HYBRID ECONOMETRIC-AI ENSEMBLE LEARNING APPROACH显示文摘Due to the complexity of economic system and the interactive effects between all kinds of economic variables and foreign trade, it is not easy to predict foreign trade volume. However, the difficulty in predicting foreign trade volume is usually attributed to the limitation of many conventional forecasting models. To improve the prediction performance, the study proposes a novel kernel-based ensemble learning approach hybridizing econometric models and artificial intelligence (AI) models to predict China's foreign trade volume. In the proposed approach, an important econometric model, the co-integration-based error correction vector auto-regression (EC-VAR) model is first used to capture the impacts of all kinds of economic variables on Chinese foreign trade from a multivariate linear anal- ysis perspective. Then an artificial neural network (ANN) based EC-VAR model is used to capture the nonlinear effects of economic variables on foreign trade from the nonlinear viewpoint. Subsequently, for incorporating the effects of irregular events on foreign trade, the text mining and expert's judgmental adjustments are also integrated into the nonlinear ANN-based EC-VAR model. Finally, all kinds of economic variables, the outputs of linear and nonlinear EC-VAR models and judgmental adjustment model are used as input variables of a typical kernel-based support vector regression (SVR) for en- semble prediction purpose. For illustration, the proposed kernel-based ensemble learning methodology hybridizing econometric techniques and AI methods is applied to China's foreign trade volume predic- tion problem. Experimental results reveal that the hybrid econometric-AI ensemble learning approach can significantly improve the prediction performance over other linear and nonlinear models listed in this study. | Lean YU Shouyang WANG Kin Keung LAI | 2008 | Journal of Systems Science & Complexity2008，21，1： | 5 |
| 5 | 转移性乳腺癌生存者应对方式的研究进展显示文摘阐述了应对的概念,介绍了国内外转移性乳腺癌生存者应对方式的特点、影响因素和干预方法,并提出对转移性乳腺癌生存者应对方式实践与研究的思考与展望。 | 郭奕嫱 鞠庆梅 尤渺宁 Azlina Yusuf 辛小林 李惠平 Soon Lean Keng | 2017 | 护理研究(中旬版)2017，31，1： | 5 |
| 6 | Risk factors and outcomes of delayed graft function in renal transplant recipients receiving a steroid sparing immunosuppression protocol显示文摘AIM To analyse the risk factors and outcomes of delayed graft function(DGF) in patients receiving a steroid sparing protocol. METHODS Four hundred and twenty-seven recipients of deceased donor kidney transplants were studied of which 135(31.6%) experienced DGF. All patients received monoclonal antibody induction with a tacrolimus based, steroid sparing immunosuppression protocol.RESULTS Five year patient survival was 87.2% and 94.9% in the DGF and primary graft function(PGF) group respectively, P = 0.047. Allograft survival was 77.9% and 90.2% in the DGF and PGF group respectively, P < 0.001. Overall rejection free survival was no different between the DGF and PGF groups with a 1 and 5 year rejection free survival in the DGF group of 77.7% and 67.8% compared with 81.3% and 75.3% in the PGF group, P = 0.19. Patients with DGF who received IL2 receptor antibody induction were at significantly higher risk of rejection in the early post-transplant period than the group with DGF who received alemtuzumab induction. On multivariate analysis, risk factors for DGF were male recipients, recipients of black ethnicity, circulatory death donation, preformed DSA, increasing cold ischaemic time, older donor age and dialysis vintage.CONCLUSION Alemtuzumab induction may be of benefit in preventing early rejection episodes associated with DGF. Prospective trials are required to determine optimal immunotherapy protocols for patients at high risk of DGF. | Michelle Willicombe Anna Rizzello Dawn Goodall Vassilios Papalois Adam G Mc Lean David Taube | 2017 | World Journal of Transplantation2017，7，1： | 4 |
| 7 | Blockchain-driven supply chain finance solution for small and medium enterprises显示文摘Blockchain has attracted much attention in recent years with the development of cryptocurrency and digital assets.As the underlying technology of cryptocurrency,blockchain has numerous benefits,such as decentralization,collective maintenance,tamper-resistance,traceability,and anonymity.The potential of the blockchain technology(BT)is widely recognized in the financial field.Although some scholars have proposed the combination of blockchain and supply chain finance(SCF),the details of this combination is rarely mentioned.This study first analyzes the coupling between SCF and blockchain technology.Second,the conceptual framework of blockchain-driven SCF platform(BcSCFP)is presented.Third,the operation process of three SCF models on the BcSCFP is proposed.Finally,a case study combined with actual events is conducted.This paper has a positive practical significance in the operation and management of banks and loan enterprises. | Jian LI Shichao ZHU Wen ZHANG Lean YU | 2020 | Frontiers of Engineering Management2020，7，4： | 3 |
| 8 | Human resource allocation for multiple scientific research projects via improved pigeon-inspired optimization algorithm显示文摘Aiming at the complex and restrictive characteristics of human resource allocation in multiple scientific university research projects, an improved pigeon-inspired optimization(IPIO) algorithm is proposed wherein loss minimization and the shortest project delay time are considered as optimization goals. Firstly, mathematical modelling of the problem is carried out, and the multi-objective optimization problem is transformed into a single-objective optimization problem by means of a weighted solution. In the second step, the traditional pigeon-inspired optimization(PIO) algorithm is discretized, and an adaptive parameter strategy is adopted to improve the shortcomings of the algorithm itself. Finally, by comparing the simulation results with the original algorithm and the genetic algorithm in the optimization of human resource allocation in multiple projects, the feasibility and superiority of the proposed algorithm in the optimization of human resource allocation in multi-scientific research projects is verified. | LIU ChuanBin MA YongHong YIN Hang YU LeAn | 2021 | Science China(Technological Sciences)2021，64，1： | 3 |
| 9 | A Novel Hybrid FA-Based LSSVR Learning Paradigm for Hydropower Consumption Forecasting显示文摘Due to the nonlinearity and nonstationary of hydropower market data, a novel hybrid learning paradigm is proposed to predict hydropower consumption, by incorporating firefly algorithm(FA) into least square support vector regression(LSSVR), i.e., FA-based LSSVR model. In the novel model, the powerful and effective artificial intelligence(AI) technique, i.e., LSSVR, is employed to forecast hydropower consumption. Furthermore, a promising AI optimization tool, i.e., FA, is especially introduced to address the crucial but difficult task of parameters determination in LSSVR(e.g.,hyper and kernel function parameters). With the Chinese hydropower consumption as sample data,the empirical study has statistically confirmed the superiority of the novel FA-based LSSVR model to other benchmark models(including existing popular traditional econometric models, AI models and similar hybrid LSSVRs with other popular parameter searching tools), in terms of level and directional accuracy. The empirical results also imply that the hybrid FA-based LSSVR learning paradigm with powerful forecasting tool and parameters optimization method can be employed as an effective forecasting tool for not only hydropower consumption but also other complex data. | TANG Ling WANG Zishu LI Xinxie YU Lean ZHANG Guoxing | 2015 | Journal of Systems Engineering and Electronics2015，26，5： | 3 |
| 10 | How will Earth’s surface temperature change in future decades?显示文摘 | Lean Judith L. Rind David H | 2009 | Geophysical Research Letters2009，，15： | 2 |
| 11 | Option Pricing under the Double Exponential Jump-Diffusion Model with Stochastic Volatility and Interest Rate显示文摘This paper proposes an efficient option pricing model that incorporates stochastic interest rate(SIR),stochastic volatility(SV),and double exponential jump into the jump-diffusion settings.The model comprehensively considers the leptokurtosis and heteroscedasticity of the underlying asset’s returns,rare events,and an SIR.Using the model,we deduce the pricing characteristic function and pricing formula of a European option.Then,we develop the Markov chain Monte Carlo method with latent variable to solve the problem of parameter estimation under the double exponential jump-diffusion model with SIR and SV.For verification purposes,we conduct time efficiency analysis,goodness of fit analysis,and jump/drift term analysis of the proposed model.In addition,we compare the pricing accuracy of the proposed model with those of the Black-Scholes and the Kou(2002)models.The empirical results show that the proposed option pricing model has high time efficiency,and the goodness of fit and pricing accuracy are significantly higher than those of the other two models. | Rongda Chen Zexi Li Liyuan Zeng Lean Yu Qi Lin Jia Liu | 2017 | Journal of Management Science and Engineering2017，2，4： | 2 |
| 12 | Apolipoproteins and amyloid fibril formation in atherosclerosis显示文摘Amyloid fibrils arise from the aggregation of misfolded proteins into highly-ordered structures.The accumulation of these fibrils along with some non-fibrillar constituents within amyloid plaques is associated with the pathogenesis of several human degenerative diseases.A number of plasma apolipoproteins,including apolipoprotein(apo)A-I,apoA-II,apoC-II and apoE are implicated in amyloid formation or influence amyloid formation by other proteins.We review present knowledge of amyloid formation by apolipoproteins in disease,with particular focus on atherosclerosis.Further insights into the molecular mechanisms underlying their amyloidogenic propensity are obtained from in vitro studies which describe factors affecting apolipoprotein amyloid fibril formation and interactions.Additionally,we outline the evidence that amyloid fibril formation by apolipoproteins might play a role in the development and progression of atherosclerosis,and highlight possible molecular mechanisms that could contribute to the pathogenesis of this disease. | Chai Lean Teoh Michael D.W.Griffin Geoffrey J.Howlett | 2011 | Protein & Cell2011，2，2： | 2 |
| 13 | Specificity of choline metabolites for in vivo diagnosis of breast cancer using 1 H MRS at 1.5 T显示文摘 | Peter Stanwell Laurence Gluch David Clark Boguslaw Tomanek Luke Baker Bruno Giuffrè Cynthia Lean Peter Malycha Carolyn Mountford | 2005 | European Radiology2005，，5： | 2 |
| 14 | Increased insulin-like growth factor I mRNA expression in rat osteocytes in response to mechanical stimulation 显示文摘 | Jagger CJ Chambers TJ Chow JM | 1995 | Am J Physiol1995，268，： | 1 |
| 15 | Ovarian cancer in the elderly outcomes with neoadjuvant chemotherapy or primary eytoreduetion显示文摘 | Me Lean KA Shah CA Thompson SA | 2010 | Gynecol Oneol2010，118，1： | 1 |
| 16 | Plasma glucagon and insulin responses depend on the rate of appearance of amino acids after ingestion of different protein solutions in humans显示文摘 | Calbet J A L Mac Lean D A | 2002 | J Nutr2002，132，： | 1 |
| 17 | Quantitative analysis of the flavonoids content of commercial toma- toes, onions,lettues, and celery 显示文摘 | Crozier A Lean M E Medonald M S | 1997 | Journal of Agricul- tural and Food Chemistry1997，45，： | 1 |
| 18 | Associations of body composition with Type 2 diabetes mellitus显示文摘 | Han TS Feskens EJ Lean ME | 1998 | Diabet Med1998，15，： | 1 |
| 19 | International momentum strategies: a stochastic dominance approach显示文摘 | Fong W M Wong W K Lean H H | 2005 | Journal of Financial Markets2005，，8： | 1 |
| 20 | Preparation, X ray structure and properties of a hexabrominated, symmet ric indole trimer and its TCNQ adduet: a new route to func tional molecular systems显示文摘 | Robertson N Parsons S Mac Lean E J | 2000 | J Mat Chem2000，10，9： | 1 |
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