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    题名 作者 年代 出处 被引量
1高原泥炭记录揭示的全新世季风快速变化显示文摘利用青藏高原东北缘的泥炭沉积记录,重建了该地区全新世冬、夏季风快速波动历史,清晰地识别出9次可与北大西洋浮冰碎屑事件及低纬海面降温事件相对比的气候干冷事件。总有机碳含量频谱分析揭示的1 428、512、2552、17 a气候准周期,表明中纬度地区百年至千年尺度气候韵律的存在,全新世气候快速变化具有全球性。鲜锋 周卫健 于学峰 卢雪峰 A J T Jull Lars G Franzén 2006海洋地质与第四纪地质2006,26,1:9
2CT diagnosis of recurrence after pancreatic cancer:Is there a pattern?显示文摘AIM:To investigate predilection sites of recurrence of pancreatic cancer by computed tomography(CT)in follow-up after surgery. METHODS:Seventy seven patients with recurrence after pancreatic cancer surgery were retrospectively identified.The operative technique,R-status,T-stage and development of tumor markers were evaluated. Two radiologists analyzed CT scans with consensus readings.Location of local recurrence,lymph node recurrence and organ metastases were noted.Surgery and progression of findings on follow-up CT were con-sidered as reference standard. RESULTS:The mean follow-up interval was 3.9± 1.8 mo,with a mean relapse-free interval of 12.9± 10.4 mo.The predominant site of recurrence was local (65%),followed by lymph node(17%),liver metastasis (11%)and peritoneal carcinosis(7%).Local recurrence emerged at the superior mesenteric artery(n=28),the hepatic artery(n=8),in an area defined by the surrounding vessels:celiac trunk,portal vein,inferior vena cava(n=22),and in a space limited by the mesenteric artery,portal vein and inferior vena cava(n=17). Lymph node recurrence occurred in the mesenteric root and left lateral to the aorta.Recurrence was confirmed by surgery(n=22)and follow-up CT(n=55).Tumor markers[carbohydrate antigen 19-9(CA19-9),carcinoembryonic antigen(CEA)]increased in accordance with signs of recurrence in most cases(86%CA19-9;79.2% CEA). CONCLUSION:Specific changes of local and lymph node recurrence can be found in the course of the cardinal peripancreatic vessels.The superior mesenteric artery is the leading structure for recurrence.Tobias Heye Nicola Zausig Miriam Klauss Reinhard Singer Jens Werner Gtz Martin Richter Hans-Ulrich Kauczor Lars Grenacher 2011World Journal of Gastroenterology2011,17,9:6
3新型PET泡沫AIREX~ T92的性能特点试验研究显示文摘在当前复合材料夹层结构用泡沫芯材领域中,PVC泡沫由于其良好的综合力学性能占据着主导地位,PET泡沫的应用则由于其脆性而受到一定的限制,加铝(Alcan)复合材料集团芯材事业部在其AIREX(T91基础上研制的新型PET泡沫AIREX(T92成功突破了这个弱点。本文对AIREX(T92泡沫的静、动态力学性能,高温下的力学性能以及高温下的尺寸稳定性进行了试验研究。结果表明,AIREX(T92作为一款综合性能优异的结构泡沫芯材,可以用于风能、游艇和轨道交通等各个领域。姚辉 Moritz Pieper Lars Massüger Roman Gtzi 李岩 2009材料工程2009,37,S2:6
4参与式管理解决冲突:遥感和GIS用作瑞典北部驯鹿业土地利用需求信息交流的工具显示文摘在解决复杂的土地管理问题时,对短缺或者有争执的资源进行地理评估有助于不同利益相关者之间沟通认识和增进理解。本文中,我们说明如何使用遥感和GIS收集和汇总瑞典北部驯鹿放牧者和其他土地使用者(林业、采矿业、旅游业等等)的土地使用活动及使用模式的信息。该项目主要基于最终的土地使用者,即驯鹿放牧者们所做的工作,体现了面向土地使用者的新的努力。发展驯鹿业的土地利用规划的基础有以下几个方面:收集并数字化传统的驯鹿栖息地生态学和景观信息;将这些信息与来自野外调查及基于人造卫星观测的植被分类结果整合;绘制其他土地使用者的活动情况图。最终的土地利用规划提供的信息有利于驯鹿放牧者与其他利益相关者之间的磋商,并有助于驯鹿管理实施。该项目可作为一种大众参与和计划编制的模式,从而使本土信息和先进的遥感技术融入一个交互式的过程中。Per Sandstrm Tina Granqvist Pahlén Lars Edenius Hans Tφmmervik Olle Hagner Leif Hemberg Hkan Olsson Karin Baer Thomas Stenlund Lars Gran Brandt Mikael Egberth 周立志 程利群 2003AMBIO-人类环境杂志2003,32,8:4
5Heme oxygenase-1 overexpression increases liver injury after bile duct ligation in rats显示文摘AIM: To investigate the effects of heme oxygenase-1 (HO-1) against oxidant-induced injury caused by bile duct ligation (BDL). METHODS: Either cobalt protoporphyrin (CoPP), a HO-1 inducer, or saline were injected intraperitoneally in male SD-rats. Three days later, BDL or sham-operations were performed. Rats were sacrificed 3 wk after BDL and livers were harvested for histology. Fibrosis was evaluated by sirius red staining and image analysis. Alpha-smooth muscular actin, which indicates activation of stellate cells, was detected by immunohistochemical staining, and cytokine and collagen-Ⅰα (Col-Ⅰα) mRNA expression was detected using RNase protection assays. RESULTS: Serum alanine transaminase increased 8-fold above normal levels one day after BDL. Surprisingly, enzyme release was not reduced in rats receiving CoPP. Liver fibrosis was evaluated 3 wk after BDL and the sirius red-positive area was found to be increased to about 7.8%. However, in CoPP pretreated rats sirius red- positive areas were increased to about 11.7% after BDL. Collagen-Ⅰα and TGF-β mRNA increased significantly by BDL. Again, this effect was increased by HO-1 overexpression.CONCLUSION: Hepatic fibrosis due to BDL is not reduced by the HO-1 inducer CoPP. In contrast, HO-1 overexpression increases liver injury in rats under conditions of experimental chronic cholestasis.Matthias Froh Lars Conzelmann Peter Walbrun Susanne Netter Reiner Wiest Michael D Wheeler Mark Lehnert Takehiko Uesugi Jurgen Scholmerich Ronald G Thurman 2007World Journal of Gastroenterology2007,13,25:4
6Role of HSP-90 for increased nNOS-mediated vasodilation in mesenteric arteries in portal hypertension显示文摘AIM:To explore the role of heat shock protein-90 (HSP-90) for nitrergic vasorelaxation in the splanchnic circulation in rats with and without portal hypertension. METHODS: Neuronal nitric oxide synthase (nNOS) and HSP-90 were analyzed by immunofluorescence, western blotting and co-immunoprecipitation in the mesenteric vasculature and isolated nerves of portal-vein-ligated (PVL) rats and sham operated rats. In vitro perfused de-endothelialized mesenteric arterial vasculature was preconstricted with norepinephrine (EC80) and tested for nNOS-mediated vasorelaxation by periarterial nerve stimulation (PNS, 2-12 Hz, 45V) before and after incubation with geldanamycin (specific inhibitor of HSP-90 signalling, 3 μg/mL) or L-NAME (non-specific NOSblocker, 10-4 mol/L). RESULTS: nNOS and HSP-90 expression was significantly increased in mesenteric nerves from PVL as compared to sham rats. Moreover, nNOS and HSP-90 were visualized in mesenteric nerves by immunofluorescence and immunoprecipitation of nNOS co-immunoprecitated HSP-90 in sham and PVL rats. PNS induced a frequencydependent vasorelaxation which was more pronounced in PVL as compared to sham rats. L-NAME and geldanamycin markedly reduced nNOS-mediated vasorelaxation abrogating differences between the study groups. The effect of L-NAME and geldanamycin on nNOS-mediated vasorelaxation was significantly greater in PVL than in sham animals. However, no difference in magnitude of effect between L-NAME and geldanamycin was noted. CONCLUSION: HSP-90 acts as a signalling mediator of nNOS-dependent nerve mediated vascular responses in mesenteric arteries, and the increased nitrergic vasorelaxation observed in portal hypertension is mediated largely by HSP-90.Lukas Moleda Lars Jurzik Matthias Froh Erwin Gbele Claus Hellerbrand Rainer H Straub Jürgen Schlmerich Reiner Wiest 2010World Journal of Gastroenterology2010,16,15:4
7In Situ Etching for Total Control Over Axial and Radial Nanowire Growth显示文摘We report a method using in situ etching to decouple the axial from the radial nanowire growth pathway,independent of other growth parameters.Thereby a wide range of growth parameters can be explored to improve the nanowire properties without concern of tapering or excess structural defects formed during radial growth.We demonstrate the method using etching by HCl during InP nanowire growth.The improved crystal quality of etched nanowires is indicated by strongly enhanced photoluminescence as compared to reference nanowires obtained without etching.Magnus T.Borgström Jesper Wallentin Johanna Trägårdh Peter Ramvall Martin Ek LReine Wallenberg Lars Samuelson Knut Deppert 2010Nano Research2010,3,4:4
8Variations in serum myoglobin after a 2-min isokinetic exercise test and the effects of training显示文摘Lars -Eric Roxin Per Venge G?ran Friman 1984European Journal of Applied Physiology and Occupational Physiology1984,,:2
9Fabrication of 45° Mirrors Together with Well-Defined V-Grooves Using Wet Anisotropic Etching of Silicon显示文摘Carola Strandman Lars Rosengren Hakan G A Elderstig 1995Journal of Microelectromechanical Systems1995,4,4:2
10Analysis of heavy metals in road-deposited sediments 显示文摘Lars H Ashantha G Godwin A A 2006Analytica Chimica Acta2006,571,:1
11TAT-apoptin is efficiently delivered and induces apoptosis in cancer cells显示文摘Lars G Hugh P Joop G 0,,05:1
12Measurement of vasoac- tive neuropeptides in biological materials: Problems and pitfalls from 30 years of experience and novel future approa- ches显示文摘LARS E ROLF E PETER J G 2010Cephalalgia2010,30,:1
13Correlation between pectate lyase activity and ability of diazotrophic Klebsiella oxytoca VN 13 to penetrate into plant tissues 显示文摘Kovtunovych G Lar O Kamalova S Kordyum V Kleiner D Kozyrovska N 1999Plant Soil1999,215,1:1
14Highly efficient separation of isomeric epoxy fatty acids by micel|ar elec- trokinetic chromatography 显示文摘Hong Wan Lars G Blomberg 1997Electrophoresis1997,20,:1
15A retrospective study of 50 cas- es prior to the calcimimetics era显示文摘Conzo G Perna AF Impaet of parathyroideetomy on cardiovascu- lar outcomes and survival in chronic hemodialysis patients with secondary hyperparathyroidism 2013BMC Surgery2013,13,2:1
16Nanocrystalline diamond impedimetric aptasensor for the label-free detection of human IgE显示文摘DINH T T VERONIQUE V LARS G 2011Biosenssors&Bioelectronics2011,26,6:1
17Scalability of multiwavelength switching networks: Crosstalk analysis显示文摘 Popp L C Mats G 1999Journal of lightwave technology1999,17,1:1
18Phosphorusretention in filter materials for wastewater treatment and itssubsequent suitability for plant production 显示文摘LARS D H KIETLINSKA A RENNMAN G 2006BiosourceTechnology2006,97,:1
19A Case-study of Mesoscale Spectra of Wind and Temperature,Observed and Simulated显示文摘Larsén X G Larsen S R Badger M 2011Quarterly Journal of the Royal Meteorological Society2011,137,654:1
20Investigation of Grease Flow in a Rectangular Channel Including Wall Slip Effects Using Microparticle Image V eloeimetry 显示文摘Lars G W 2010Tribology Transactions2010,53,4:1
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