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| 1 | The plant hormone zeatin riboside inhibits T lymphocyte activity via adenosine A2A receptor activation显示文摘细胞激动素是在植物生长和开发的多重方面起一个不可分的作用的植物荷尔蒙。然而,在哺乳动物的系统的细胞激动素的生物功能大部分是 uncharacterized。自然地发生的细胞激动素玉米素核糖甙最近被表明了激活2A受体,它是广泛地包括免疫系统房间由各种各样的房间类型表示了的哺乳动物的腺苷,与 A 的激活 2A在房间的规定起一个作用的 R 在天生、适应的免疫包含了。我们第一次证明玉米素核糖甙经由 A 调制哺乳动物的免疫系统活动 2AR 依赖的机制。明确地,玉米素核糖甙处理由 T 淋巴细胞导致周期的腺苷 monophosphate (营地)的生产并且由 CD3 +干扰素( IFN )的 CD4 + T 房间-γ, IL-2 ,肿瘤坏死因素( TNF )-α, IL-4 和 IL-13 ,并且由 CD3 + IFN-γ 的 CD8 + T 房间;, IL-2 和 TNF-α ;。另外,由激活的 T 淋巴细胞的 CD25, CD69 和 CD40L 的 upregulation 被玉米素核糖甙调制。玉米素核糖甙处理 potently 也禁止导致 thioglycollate 的腹白细胞增多。玉米素核糖甙的 immunomodulatory 活动被合作处理与选择 A 堵住 2A R 对手 ZM241385。这些数据建议那玉米素核糖甙作为一个哺乳动物的 immunomodulatory 代理人拥有治疗学的潜力。 | Courtney M Lappas | 2015 | Cellular & Molecular Immunology2015，12，1： | 3 |
| 2 | Phospholipase A2 isozymes in pregnancy and parturition显示文摘 | Lappas M Rice GE | 2004 | Prostaglandins Leukot Essent Fatty Acids2004，70，2： | 1 |
| 3 | Biomass pyrolysis in a circulating fluid bed reactor for the production of fuels and chemicals 显示文摘 | LAPPAS A A SAMOLADA M C IATRIDIS D K | 2002 | Fuel2002，81，： | 1 |
| 4 | In response to oxidative stress, the expression of inflammatory cytokines and antioxidant enzymes are impaired in placenta, but not adipose tissue, of women with gestational diabetes显示文摘 | Lappas M Mittion A Permezel M | 2010 | Endocrinology2010，204，1： | 1 |
| 5 | In response to oxidative stress,the expression of inflammatory cytokines and antioxidant enzymes are impaired in placenta,but not adipose tissue,of women with gestational diabetes显示文摘 | Lappas M Mitton A Permezel M | 2010 | J Endocrinol2010，204，1： | 1 |
| 6 | Biomass pyrolysis in a circulating fluid bed reactor for the production of fuels and chemicals显示文摘 | LAPPAS A A SAMOLADA M C IATRIDIS D K | 2002 | Fuel2002，81，16： | 1 |
| 7 | Leptin and adiponectin stimulate the release of proinflammatory cytokines and prostaglandins from human placenta and maternal adipose tissue via nuclear factorkappa B,peroxisomal proliferator-activated receptor-and extracellularlyregulated kinase1/2显示文摘 | Permezel M Rice GE | 2005 | Endocrinology2005，146，8： | 1 |
| 8 | Leptin and adiponectin stimulate the release of proinflammatory cytokines and prostaglandins from human placenta and maternal adipose tissue via NF-κB,PPAR-γ and ERK 1/2显示文摘 | Lappas M Permezel M Rice GE | 2005 | Endocrinology2005，146，8： | 1 |
| 9 | Nuclear factor kappa B regulation of proinflammatory cytokines in human gestational tissues in vitro显示文摘 | Permezel M Georgiou H M | 2002 | Biol Reprod2002，67，2： | 1 |
| 10 | The role and regulation of the nuclear factor kappa B signalling pathway in human labour 显示文摘 | Lappas M Rice GE | 2007 | Placenta2007，28，： | 1 |
| 11 | N-Acetyl-cysteine inhibits phospho-lipid metabolism,proinflammatory cytokine release,protease activity,and nuclear factor-kappaB deoxyribonucleic acid-binding activity in human fetal membranes in vitro显示文摘 | Lappas M Permezel M Rice GE | 2003 | J Clin Endocrinol Metab2003，88，4： | 1 |
| 12 | KLF5 regulates infection - and inflammation - induced pro - labour mediators in human myometrium 显示文摘 | Lappas M | 2015 | Reproduction2015，149，5： | 1 |
| 13 | Effect of pre-existing maternal obesity,gestational diabetes and adipokines on the expression of genes involved in lipid metabolism in adipose tissue显示文摘 | Lappas M | 2014 | Metabolism2014，63，2： | 1 |
| 14 | Phospholipase A2 isozymes in pregnancy and parturition显示文摘 | Lappas M Rice GE | 2004 | Prostaglandins Leukot Essent Fatty Acids2004，70，2： | 1 |
| 15 | Release and regulation of leptin,resistin and adiponectin from human placenta,fetal membranes,and maternal adipose tissue and skeletal muscle from normal and gestational diabetes mellitus-complicated pregnancies显示文摘 | Lappas M Yee K Permezel M | 2005 | J Endocrinol2005，186，3： | 1 |
| 16 | Nuclear factor kappa B regulation of proinflammatory cytokines in human gestational tissues in vitro.显示文摘 | Lappas M Pernezel M Cmrgiou HM | | 0，，： | 1 |
| 17 | Activation of inflammasomes in adipose tissue of women with gestational diabetes显示文摘 | Lappas M | 2014 | Mol Cell Endocrinol2014，382，1： | 1 |
| 18 | The role of oxidative stress in the pathophysiology of gestational diabetes mellitus 显示文摘 | LAPPAS M HIDEN U DESOYE G | 2011 | Antioxidants & Redox Signaling2011，15，12： | 1 |
| 19 | Leptin and adiponectin stimulate the release of proinflammatory cytokines and prostaglandins from human placenta and maternal adipose tissue via nuclear factor-kappaB,peroxisomal proliferator-activated receptor-gamma and extracellularly regulated kinase 1/2显示文摘 | Permezel M Rice GE | 2005 | Endocrinology2005，146，： | 1 |
| 20 | In response to oxidative stress, the expression of inflammatory eytokines and antioxidant enzymes are impaired in plaeenta~but not adipose tissue,of women with gestational diabetes 显示文摘 | Lappas M Mitton A Permezel M | 2010 | J Endoerinal2010，204，1： | 1 |
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