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| 1 | Sur la fonction ζ(s) de Riemann et le nombre des nombres premirs inférieurs áune limite donnée显示文摘 | de la Vallée Poussin C J | 1900 | Mem Acad Belgique1900，59，1： | 1 |
| 2 | A 70 - Kilodalton recombinant heat shock protein of Candida albicans is highly immunogenic and enhances systemic murine candidiasis显示文摘 | Bromuro C La Valle R Sandini S | 1998 | Infect Immun1998，66，5： | 1 |
| 3 | Bi2O3 vaporization from ZnO-based varistors 显示文摘 | PEITEADO M de la RUBIA M A VELASCO M J VALLE F J CABALLERO A C | 2005 | J Eur Ceram Soc2005，25，9： | 1 |
| 4 | Quatre leons sur les functions quasi-analytiques de variable显示文摘 | Vallée Poussin C De La | 1924 | Bulletin de la sociétémathématique de France1924，52，： | 1 |
| 5 | Respiratory and cardiovascular function at rest and during exercise testing in a healthy working population:effects of outdoor traffic air pollution显示文摘 | VOLPINO P TOMEI F LA VALLE C | 2004 | Occupational Medicine2004，54，7： | 1 |
| 6 | A 70-kDa recombinant heat shock protein of Candida albicans is highly immunogenic and enhances systemic murine candidiasis显示文摘 | Bromuro C La Valle R Sandini S | 1998 | Infect Immun1998，66，5： | 1 |
| 7 | Bi2O3 vaporization from ZnO-based varistors显示文摘 | PEITEADO M de la RUBIA M A VELASCO M J VALLE F J CABALLERO A C | 2005 | Journal of the European Ceramic Society2005，25，9： | 1 |
| 8 | Water Splitting on Semiconductor Catalysts under Visible Light Irradiation显示文摘 | Navarro Yerga R M Ivarez GalvOu M C Del Valle F Villnria De La Mann J A Fien'n J 1 | 2009 | Chemsuschem2009，2，6： | 1 |
| 9 | Prospective application of a bleeding and ischemic risks-adjusted antithrombotic protocol in elderly patients revascularized with everolimus-eluting stents:EPIC05-Sierra75 study显示文摘OBJECTIVES Elderly patients show a higher incidence of ischemic and bleeding events after percutaneous transluminal coron-ary intervention(PCI).We sought to investigate outcomes in elderly patients treated with antithrombotic strategy guided by bleeding and ischemic risks after revascularization with last generation everolimus-eluting stent(EES).METHODS Prospective multicenter registry including patients over 75 years revascularized with EES and antithrombotic ther-apy guided by clinical presentation,PCI complexity and PRECISE DAPT score.Co-primary safety endpoints were:(1)composite of cardiac death,myocardial infarction and stent thrombosis and;(2)bleeding(BARC 2-5).Primary efficacy endpoint was target lesion revascularization.A matched group of patients revascularized with current drug-eluting stents and no such tailored antith-rombotic therapy was used as control.RESULTS Finally,1064 patients were included in SIERRA-75 cohort,80.8±4.2 years,36.6%women,71%acute coronary syn-dromes(ACS)and 53.6%complex PCI.Co-primary safety endpoint of major adverse cardiovascular events was met in 6.2%,co-primary safety endpoint of bleeding in 7.8%and primary efficacy endpoint of TKLR in 1.5%.The multivariable adjusted model showed no significant association of the prescribed short/long dual antiplatelet therapy(DAPT)durations with any endpoint suggesting a well tailored therapy.No stent thrombosis reported in the subgroup with 1-3 months DAPT duration.As compared to control group,bleeding BARC 2-5 was significantly lower in SIERRA-75 group(7.4%vs.10.2%,P=0.04)as well as the net safety-efficacy endpoint(14.3%vs.18.5%,P=0.02).CONCLUSIONS In elderly population,the application of this risks-adjusted antithrombotic protocol after revascularization with last generation EES seems to be associated with an improved prognosis in terms of ischemic and bleeding outcomes. | Jose M de la Torre Hernandez Ramon Lopez Palop Jesus M Jimenez Mazuecos Pilar Carrillo Sáez Alejandro Gutierez-Barrios Eduardo Pinar Belen Cid Luis Fernandez Tamara Garcia Camarero Cristóbal Urbano-Carrillo Juan F Oteo Dominguez Victor A Jimenez Diaz Antonio EGomez Menchero Eladio Galindo Fernández Juan GCórdoba Soriano Raymundo Ocaranza Eduardo ArroyoÚcar Koldobika Garcia San Roman Silvio Leal Ginés Martínez Cáceres Jose A Linares Vicente Georgina Fuertes Ferre Xavier Carrillo Juan CRama Merchán Catia Costa Juan Sanchis Renato Fernandes Alberto Rodrigues Jose M Vegas Valle Hélder Pereira Armando Perez de Prado | 2022 | Journal of Geriatric Cardiology2022，19，5： | 0 |
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